P. Hake

发表

Age‐Dependent Changes in AMPK Metabolic Pathways in the Lung in a Mouse Model of Hemorrhagic Shock

Lindsey R. Klingbeil, P. Kim, G. Piraino, 2017, American journal of respiratory cell and molecular biology.

Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis*

H. Wong, P. Hake, B. Zingarelli, 2003, Critical care medicine.

Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation.

S. Cuzzocrea, P. Hake, B. Zingarelli, 1998, Free radical biology & medicine.

Proinsulin c-peptide exerts beneficial effects in endotoxic shock in mice

G. Piraino, M. O’connor, P. Hake, 2007, Critical care medicine.

Epigallocatechin, a Green Tea Polyphenol, Attenuates Myocardial Ischemia Reperfusion Injury in Rats

Timothy J. Burroughs, H. Wong, P. Hake, 2004, Molecular medicine.

Immunopathology and Infectious Diseases Peroxisome Proliferator-Activated Receptor Regulates Inflammation via NF-B Signaling in Polymicrobial Sepsis

G. Piraino, M. O’connor, P. Hake, 2010 .

Phosphorylation of Extracellular Signal-Regulated Kinase (ERK)-1/2 Is Associated with the Downregulation of Peroxisome Proliferator-Activated Receptor (PPAR)-γ during Polymicrobial Sepsis

G. Piraino, P. Hake, B. Zingarelli, 2010, Molecular medicine.

Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation.

S. Cuzzocrea, P. Hake, B. Zingarelli, 1998, European journal of pharmacology.

Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.

S. Cuzzocrea, E. Kun, M. O’connor, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Protective effect of melatonin in carrageenan‐induced models of local inflammation: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity

S. Cuzzocrea, P. Hake, B. Zingarelli, 1997, Journal of pineal research.

Sesquiterpene Lactone Parthenolide, an Inhibitor of I&kgr;B Kinase Complex and Nuclear Factor-&kgr;B, Exerts Beneficial Effects in Myocardial Reperfusion Injury

H. Wong, P. Hake, B. Zingarelli, 2002, Shock.

Inhibitors of poly (ADP-ribose) polymerase modulate signal transduction pathways in colitis.

M. O’connor, P. Hake, B. Zingarelli, 2003, European journal of pharmacology.

Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor &ggr;*

Timothy J. Burroughs, H. Wong, J. Solomkin, 2009, Critical care medicine.

Ciglitazone ameliorates lung inflammation by modulating the inhibitor &kgr;B protein kinase/nuclear factor-&kgr;B pathway after hemorrhagic shock

Ranjit S. Chima, G. Piraino, P. Hake, 2008, Critical care medicine.

Beneficial effects of mercaptoethylguanidine, an inhibitor of the inducible isoform of nitric oxide synthase and a scavenger of peroxynitrite, in a porcine model of delayed hemorrhagic shock.

P. Hake, C. Szabó, A. Salzman, 1999, Critical care medicine.

Therapeutic effect of epigallocatechin-3-gallate in a mouse model of colitis.

Timothy J. Burroughs, H. Wong, M. O’connor, 2008, European journal of pharmacology.

Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.

V. Malhotra, H. Wong, M. O’connor, 2002, Molecular pharmacology.

Suppression of experimental allergic encephalomyelitis by administration of 5-IODO-6-Amino-1,2,benzopyrone. A novel inhibitor of poly (ADP-ribose) synthetase

P. Hake, C. Szabó, A. Salzman, 1998 .

Reply to Angé et al.

G. Piraino, M. O’connor, P. Hake, 2019, American journal of physiology. Heart and circulatory physiology.

Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1.

B. Aronow, H. Wong, M. O’connor, 2004, American journal of physiology. Heart and circulatory physiology.

15-DEOXY-Δ12,14-PROSTAGLANDIN J2 (15D-PGJ2), A PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR γ LIGAND, REDUCES TISSUE LEUKOSEQUESTRATION AND MORTALITY IN ENDOTOXIC SHOCK

Timothy J. Burroughs, M. O’connor, P. Hake, 2005 .

Inducible Nitric Oxide Synthase Is Not Required in the Development of Endotoxin Tolerance in Mice

P. Hake, B. Zingarelli, J. Cook, 2002, Shock.

Protective effects of isohelenin, an inhibitor of nuclear factor κB, in endotoxic shock in rats

H. Wong, P. Hake, B. Zingarelli, 2002 .

INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE AMELIORATE MYOCARDIAL REPERFUSION INJURY BY MODULATION OF ACTIVATOR PROTEIN-1 AND NEUTROPHIL INFILTRATION

M. O’connor, P. Hake, B. Zingarelli, 2005, Shock.

Liver X Receptor &agr; Activation with the Synthetic Ligand T0901317 Reduces Lung Injury and Inflammation After Hemorrhage and Resuscitation Via Inhibition of the Nuclear Factor &kgr;B Pathway

A. Lentsch, G. Piraino, M. O’connor, 2011, Shock.

THE GREEN TEA POLYPHENOL EPIGALLOCATECHIN-3-GALLATE IMPROVES SYSTEMIC HEMODYNAMICS AND SURVIVAL IN RODENT MODELS OF POLYMICROBIAL SEPSIS

H. Wong, J. Catravas, P. Hake, 2007, Shock.

Poly(ADP-Ribose) Polymerase-1 Regulates Activation of Activator Protein-1 in Murine Fibroblasts1

M. O’connor, P. Hake, B. Zingarelli, 2003, The Journal of Immunology.

Fibroblasts Activation of Activator Protein-1 in Murine Poly ( ADP-Ribose ) Polymerase-1 Regulates

M. O’connor, P. Hake, B. Zingarelli, 2003 .

Protection against hypoxia-reoxygenation in the absence of poly (ADP-ribose) synthetase in isolated working hearts.

G. Grupp, I. Grupp, P. Hake, 1999, Journal of molecular and cellular cardiology.

The AMPK Activator Aicar Ameliorates Age-Dependent Myocardial Injury in Murine Hemorrhagic Shock

Lindsey R. Klingbeil, G. Piraino, M. O’connor, 2017, Shock.

Protective effects of isohelenin, an inhibitor of nuclear factor κB, in endotoxic shock in rats

H. Wong, P. Hake, B. Zingarelli, 2002 .

Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis

P. Hake, L. Virág, C. Szabó, 2001, Journal of Neuroimmunology.

Ciglitazone, a novel inhibitor of lung apoptosis following hemorrhagic shock.

G. Piraino, M. O’connor, P. Hake, 2010, International journal of clinical and experimental medicine.

Liver apoptosis is age dependent and is reduced by activation of peroxisome proliferator-activated receptor-gamma in hemorrhagic shock.

G. Piraino, M. O’connor, P. Hake, 2010, American journal of physiology. Gastrointestinal and liver physiology.

3‐AMINOBENZAMIDE, AN INHIBITOR OF POLY (ADP‐RIBOSE) SYNTHETASE, IMPROVES HEMODYNAMICS AND PROLONGS SURVIVAL IN A PORCINE MODEL OF HEMORRHAGIC SHOCK

P. Hake, C. Szabó, A. Salzman, 1998, Shock.

Absence of inducible nitric oxide synthase modulates early reperfusion‐induced NF‐κB and AP‐1 activation and enhances myocardial damage

H. Wong, M. O’connor, P. Hake, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activator protein‐1 signalling pathway and apoptosis are modulated by poly(ADP‐ribose) polymerase‐1 in experimental colitis

Timothy J. Burroughs, G. Piraino, M. O’connor, 2004, Immunology.

Absence of Poly(ADP-ribose) Polymerase-1 Alters Nuclear Factor-κB Activation and Gene Expression of Apoptosis Regulators after Reperfusion Injury

B. Aronow, M. O’connor, P. Hake, 2003, Molecular medicine.

Age-dependent cardiac function during experimental sepsis: effect of pharmacological activation of AMP-activated protein kinase by AICAR.

G. Piraino, M. O’connor, P. Hake, 2018, American journal of physiology. Heart and circulatory physiology.

Role of matrix metalloproteinase‐8 as a mediator of injury in intestinal ischemia and reperfusion

H. Wong, Lindsey R. Klingbeil, G. Piraino, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Conditional Deletion of Cardiomyocyte Peroxisome Proliferator-Activated Receptor &ggr; Enhances Myocardial Ischemia-Reperfusion Injury in Mice

G. Piraino, M. O’connor, P. Hake, 2014, Shock.

C-peptide, a novel inhibitor of lung inflammation following hemorrhagic shock.

G. Piraino, P. Hake, B. Zingarelli, 2011, American journal of physiology. Lung cellular and molecular physiology.

Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPK&agr;1-Independent Manner

P. Kim, G. Piraino, M. O’connor, 2017, Shock.

Autophagy and mitochondrial biogenesis impairment contribute to age‐dependent liver injury in experimental sepsis: dysregulation of AMP‐activated protein kinase pathway

John R. Ledford, G. Piraino, M. O’connor, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile sepsis Model

H. Wong, Lindsey R. Klingbeil, G. Piraino, 2016, Molecular medicine.

Short-Term High Fat Feeding Increases Organ Injury and Mortality After Polymicrobial Sepsis

M. O’connor, P. Hake, B. Zingarelli, 2012, Obesity.

following hemorrhagic shock C-peptide, a novel inhibitor of lung inflammation

P. Hake, B. Zingarelli, R. Chima, 2016 .

Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock.

G. Piraino, M. O’connor, P. Hake, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Absence of endogenous interleukin 10 enhances early stress response during post-ischaemic injury in mice intestine

H. Wong, Z. Yang, P. Hake, 2001, Gut.

Combined Zinc Supplementation With Proinsulin C-Peptide Treatment Decreases the Inflammatory Response and Mortality in Murine Polymicrobial Sepsis

John R. Ledford, H. Wong, G. Piraino, 2014, Shock.

Activation of AMP-Activated Protein Kinase by A769662 Ameliorates Sepsis-Induced Acute Lung Injury in Adult Mice.

John R. Ledford, G. Piraino, M. O’connor, 2019, Shock.

Peroxisome Proliferator Activator Receptor-γ Ligands, 15-Deoxy-Δ12,14-Prostaglandin J2 and Ciglitazone, Reduce Systemic Inflammation in Polymicrobial Sepsis by Modulation of Signal Transduction Pathways 1

M. O’connor, P. Hake, B. Zingarelli, 2003, The Journal of Immunology.

Age-dependent therapeutic effects of liver X receptor-α activation in murine polymicrobial sepsis

John R. Ledford, G. Piraino, M. O’connor, 2015, Innate immunity.

SYNERGISTIC EFFECT OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-&ggr; AND LIVER X RECEPTOR-&agr; IN THE REGULATION OF INFLAMMATION IN MACROPHAGES

Timothy J. Burroughs, G. Piraino, M. O’connor, 2006, Shock.

Modulation of Signal Transduction Pathways Inflammation in Polymicrobial Sepsis by and Ciglitazone, Reduce Systemic 2 -Prostaglandin J 12,14 D Ligands, 15-Deoxy-g Peroxisome Proliferator Activator Receptor-O'Connor,

P. Hake, B. Zingarelli, J. Cook, 2003 .

Modulation of Signal Transduction Pathways Inflammation in Polymicrobial Sepsis by and Ciglitazone, Reduce Systemic 2 -Prostaglandin J 12,14 D Ligands, 15-Deoxy-g Peroxisome Proliferator Activator Receptor-O'Connor,

P. Hake, B. Zingarelli, J. Cook, 2003 .

DIVERSE CARDIOPROTECTIVE SIGNALING MECHANISMS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ LIGANDS, 15-DEOXY-Δ12,14-PROSTAGLANDIN J2 AND CIGLITAZONE, IN REPERFUSION INJURY: ROLE OF NUCLEAR FACTOR-κB, HEAT SHOCK FACTOR 1, AND AKT

Timothy J. Burroughs, H. Wong, G. Piraino, 2007, Shock.

Parthenolide, an Inhibitor of the Nuclear Factor- (cid:1) B Pathway, Ameliorates Cardiovascular Derangement and Outcome in Endotoxic Shock in Rodents

V. Malhotra, H. Wong, M. O’connor, 2002 .

Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways.

M. O’connor, P. Hake, B. Zingarelli, 2003, Journal of immunology.

Lung injury after hemorrhage is age dependent: Role of peroxisome proliferator-activated receptor &ggr;*

Timothy J. Burroughs, H. Wong, J. Solomkin, 2009, Critical care medicine.