Xinghuo Wu

发表

Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Mesenchymal Stem Cell-Derived Exosomes as a Novel Strategy for the Treatment of Intervertebral Disc Degeneration

Xinghuo Wu, Cao Yang, Lin Lu, 2022, Frontiers in Cell and Developmental Biology.

Lactylation driven by lactate metabolism in the disc accelerates intervertebral disc degeneration: A hypothesis

Xinghuo Wu, Cao Yang, Chuan Cheng, 2022, Medical Hypotheses.

G-CSF/SCF exert beneficial effects via anti-apoptosis in rabbits with steroid-associated osteonecrosis.

Hong Wang, Xinghuo Wu, Xianzhe Liu, 2013, Experimental and molecular pathology.

Palliative Surgery in Treating Painful Metastases of the Upper Cervical Spine

Xinghuo Wu, Z. Shao, Cao Yang, 2016, Medicine.

Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration.

Xinghuo Wu, Wenbin Hua, Yu Song, 2021, Biomaterials.

Remodeling phenotype of macrophages in steroid-induced osteonecrosis: switching from M1 to M2 polarization

Xinghuo Wu, Z. Shao, Cao Yang, 2015 .

Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Oxidative medicine and cellular longevity.

HtrA1 is upregulated during RANKL‐induced osteoclastogenesis, and negatively regulates osteoblast differentiation and BMP2‐induced Smad1/5/8, ERK and p38 phosphorylation

V. Rosen, Xinghuo Wu, Jinmin Zhao, 2014, FEBS letters.

Impairment of two types of circulating endothelial progenitor cells in patients with glucocorticoid-induced avascular osteonecrosis of the femoral head.

Xiaohong Wang, Xinghuo Wu, Shuhua Yang, 2013, Joint, bone, spine : revue du rhumatisme.

Effects of granulocyte colony-stimulating factor and stem cell factor, alone and in combination, on the biological behaviours of bone marrow mesenchymal stem cells

Xinghuo Wu, Shuhua Yang, Weihua Xu, 2009 .

Spinal intradural extra-arachnoid inflammatory myofibroblastic tumor (IMT): Case report and review of the literature

Xinghuo Wu, Kun Wang, Cao Yang, 2021, Journal of Clinical Images and Medical Case Reports.

Fibronectin induced ITGβ1/FAK‐dependent apoptotic pathways determines the fate of degenerative NP cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Inflammation.

Anti-apoptotic effect of insulin in the control of cell death and neurologic deficit after acute spinal cord injury in rats.

Xinghuo Wu, Yukun Zhang, De-Yu Duan, 2007, Journal of neurotrauma.

Regulation of differentiation in trabecular bone‑derived mesenchymal stem cells by T cell activation and inflammation.

Hong Wang, Xinghuo Wu, Xianzhe Liu, 2013, Oncology reports.

Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Frontiers in Cell and Developmental Biology.

Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Oxidative medicine and cellular longevity.

Amyloid protein aggregation in diabetes mellitus accelerate intervertebral disc degeneration.

Xinghuo Wu, Cao Yang, Ping Liu, 2020, Medical hypotheses.

Early and Intermediate Follow-up Results After Treatment of Degenerative Disc Disease With the Bryan Cervical Disc Prosthesis: Single- and Multiple-Level

Xinghuo Wu, Cao Yang, Shuhua Yang, 2008, Spine.

Expression and methylation levels of suppressor of cytokine signaling 3 in rheumatic arthritis synovial fibroblasts.

Xinghuo Wu, Chun-qing Meng, Hong Wang, 2019, Experimental and molecular pathology.

Functional outcome of limb‐salvage surgery with shoulder abduction brace for bone tumors around the shoulders

Hong Wang, Xinghuo Wu, Xianzhe Liu, 2014, Journal of surgical oncology.

Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Experimental & Molecular Medicine.

Biomaterial‐loaded allograft threaded cage for the treatment of femoral head osteonecrosis in a goat model

Xinghuo Wu, Cao Yang, Shuhua Yang, 2008, Biotechnology and bioengineering.

Molecular structure and the role of high‐temperature requirement protein 1 in skeletal disorders and cancers

Huazi Xu, Xinghuo Wu, Jiake Xu, 2019, Cell proliferation.

Biomechanical Evaluation of Different Surgical Approaches for the Treatment of Adjacent Segment Diseases After Primary Anterior Cervical Discectomy and Fusion: A Finite Element Analysis

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Frontiers in Bioengineering and Biotechnology.

Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

Xinghuo Wu, Wenbin Hua, Yu Song, 2019, Theranostics.

Deviation analysis for C1/2 pedicle screw placement using a three-dimensional printed drilling guide

Lin Lu, Rong Liu, Cao Yang, 2017, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

Structural augmentation with biomaterial-loaded allograft threaded cage for the treatment of femoral head osteonecrosis.

Xinghuo Wu, Xianzhe Liu, Shuhua Yang, 2010, The Journal of arthroplasty.

Wearable Health Devices in Health Care: Narrative Systematic Review

Lin Lu, Yi Xie, Jiayao Zhang, 2020, JMIR mHealth and uHealth.

Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Biochimica et biophysica acta. Molecular basis of disease.

TNF-a mediated inflammatory macrophage polarization contributes to the pathogenesis of steroid-induced osteonecrosis in mice

Xinghuo Wu, Xianzhe Liu, Z. Shao, 2015, International journal of immunopathology and pharmacology.

Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/β-catenin pathway

Xinghuo Wu, Kun Wang, Shuai Li, 2019, Arthritis Research & Therapy.

Icariin Attenuates Interleukin-1β-Induced Inflammatory Response in Human Nucleus Pulposus Cells.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Current pharmaceutical design.

Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Inflammation.

WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2022, Nature Communications.

Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, Experimental & Molecular Medicine.

Pramlintide regulation of extracellular matrix (ECM) and apoptosis through mitochondrial-dependent pathways in human nucleus pulposus cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, International journal of immunopathology and pharmacology.

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells

Xinghuo Wu, Kun Wang, Shuai Li, 2017, Journal of cellular and molecular medicine.

Full-Endoscopic Visualized Foraminoplasty and Discectomy Under General Anesthesia in the Treatment of L4-L5 and L5-S1 Disc Herniation.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Spine.

3-D Printing Technique to Aid Surgical Planning in Treatment of Floating Shoulder Injury: A Case Report

Xinghuo Wu, Cao Yang, Z. Ye, 2015 .

Clinical outcome and surgical strategies for late post-traumatic kyphosis after failed thoracolumbar fracture operation

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Medicine.

Allicin Attenuated Advanced Oxidation Protein Product-Induced Oxidative Stress and Mitochondrial Apoptosis in Human Nucleus Pulposus Cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2020, Oxidative medicine and cellular longevity.

Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits.

Xinghuo Wu, Yukun Zhang, Shuhua Yang, 2008, Joint, bone, spine : revue du rhumatisme.

Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

W. Liu, Xinghuo Wu, Kun Wang, 2018, Redox biology.

IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells

Xinghuo Wu, Kun Wang, Shuai Li, 2017, Cell Death Discovery.

Halofuginone attenuates intervertebral discs degeneration by suppressing collagen I production and inactivating TGFβ and NF-кB pathway.

Xinghuo Wu, Shuai Li, Z. Shao, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Oncotarget.

TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Inflammation.

Autophagy attenuates compression‐induced apoptosis of human nucleus pulposus cells via MEK/ERK/NRF1/Atg7 signaling pathways during intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Experimental cell research.

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy

Xinghuo Wu, Kun Wang, Shuai Li, 2020, Cell Death & Disease.

The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Clinical science.

Association between interleukin 8 -251 A/T and +781 C/T polymorphisms and osteoarthritis risk.

Bin Wu, Xinghuo Wu, Shuhua Yang, 2014, Immunology letters.

Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Oxidative medicine and cellular longevity.

Analysis of Sagittal Parameters in Patients Undergoing One- or Two-Level Closing Wedge Osteotomy for Correcting Thoracolumbar Kyphosis Secondary to Ankylosing Spondylitis

Xinghuo Wu, Wenbin Hua, Xianzhe Liu, 2017, Spine.

Incidence and risk factors of neurological complications during posterior vertebral column resection to correct severe post-tubercular kyphosis with late-onset neurological deficits: case series and review of the literature

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Journal of Orthopaedic Surgery and Research.

Adjacent segment degeneration and spinal cord compression in rigid angular kyphosis of spinal tuberculosis and its intraoperative management strategy

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, The journal of spinal cord medicine.

Transpedicular Wedge Resection Osteotomy of the Apical Vertebrae for the Treatment of Severe and Rigid Thoracic Kyphoscoliosis: A Retrospective Study of 26 Cases

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Spine deformity.

Comparative Intermediate and Long-term Results of Pedicle Screw and Hook Instrumentation in Posterior Correction and Fusion of Idiopathic Thoracic Scoliosis

Xinghuo Wu, Xianzhe Liu, Cao Yang, 2010, Journal of spinal disorders & techniques.

Full-endoscopic discectomy via the interlaminar approach for disc herniation at L4-L5 and L5-S1

Xinghuo Wu, Wenbin Hua, Shuai Li, 2018, Medicine.

Feasibility of mixed reality–based intraoperative three-dimensional image-guided navigation for atlanto-axial pedicle screw placement

Song Xu, Shuhua Yang, Cao Yang, 2019, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

Sequential correction using satellite rod for the treatment of severe rigid spinal deformity: a retrospective study of 19 cases

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, European Journal of Medical Research.

Hemivertebra excision with short-segment spinal fusion through combined anterior and posterior approaches for congenital spinal deformities in children

Xinghuo Wu, Shuhua Yang, Weihua Xu, 2010, Journal of pediatric orthopedics. Part B.

Distal adding-on after surgery in Lenke 5C adolescent idiopathic scoliosis: clinical and radiological outcomes

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, BMC Musculoskeletal Disorders.

Transpedicular Wedge Resection Osteotomy of the Apical Vertebrae for the Treatment of Severe and Rigid Thoracic Kyphoscoliosis: A Retrospective Study of 26 Cases.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019 .

Comparison of Clinical Outcomes Following Lumbar Endoscopic Unilateral Laminotomy Bilateral Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for One-Level Lumbar Spinal Stenosis With Degenerative Spondylolisthesis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2021, Frontiers in Surgery.

Clinical and Radiographic Outcomes of Modified Unilateral Open-door Laminoplasty with Posterior Muscle-Ligament Complex Preservation for Cervical Spondylotic Myelopathy.

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2019, Spine.

Comparison of lumbar endoscopic unilateral laminotomy bilateral decompression and minimally invasive surgery transforaminal lumbar interbody fusion for one-level lumbar spinal stenosis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2020, BMC Musculoskeletal Disorders.

Outcomes of discectomy by using full-endoscopic visualization technique via the interlaminar and transforaminal approaches in the treatment of L5-S1 disc herniation

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Medicine.

Comparison of the Clinical Outcomes of Full‐Endoscopic Visualized Foraminoplasty and Discectomy Versus Microdiscectomy for Lumbar Disc Herniation

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Orthopaedic surgery.

Clinical outcomes of uniportal and biportal lumbar endoscopic unilateral laminotomy for bilateral decompression in patients with lumbar spinal stenosis: A retrospective pair-matched case-control study.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, World neurosurgery.

m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency

Xinghuo Wu, Kun Wang, Yu Song, 2022, Clinical and translational medicine.

Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2020, Cell proliferation.

The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2016, Scientific Reports.

A Combination of Granulocyte Colony-Stimulating Factor and Stem Cell Factor Ameliorates Steroid- Associated Osteonecrosis in Rabbits

Xinghuo Wu, Xianzhe Liu, Yukun Zhang, 2008, The Journal of Rheumatology.

Augmenting Intracellular Cargo Delivery of Extracellular Vesicles in Hypoxic Tissues through Inhibiting Hypoxia-Induced Endocytic Recycling.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2023, ACS nano.

The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration.

Yingle Liu, Xinghuo Wu, Kun Wang, 2017, Laboratory investigation; a journal of technical methods and pathology.

The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Cell proliferation.

Outcomes of arthroscopic arthrolysis for the post-traumatic elbow stiffness

Hong Wang, Xinghuo Wu, Xianzhe Liu, 2015, Knee Surgery, Sports Traumatology, Arthroscopy.

The involvement of DDX3X in compression-induced nucleus pulposus pyroptosis.

Xinghuo Wu, Yu Song, Cao Yang, 2023, Biochemical and biophysical research communications.

Comparison of Full-Endoscopic Visualized Unilateral Laminotomy Bilateral Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for One-Level Lumbar Spinal Stenosis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2020 .

An in vivo study of the effect of c-Jun on intervertebral disc degeneration in rats

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Bioengineered.

Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Gene.

Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cells.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, International journal of molecular medicine.

Dysregulated miR-127-5p contributes to type II collagen degradation by targeting matrix metalloproteinase-13 in human intervertebral disc degeneration.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Biochimie.

Angiopoietin‐like protein 8 expression and association with extracellular matrix metabolism and inflammation during intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2019, Journal of cellular and molecular medicine.

Mixed Reality Technology Launches in Orthopedic Surgery for Comprehensive Preoperative Management of Complicated Cervical Fractures

Shuhua Yang, Xinghuo Wu, Zhewei Ye, 2018, Surgical innovation.

Author Correction: WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2022, Nature Communications.

G3BP1 coordinates lysophagy activity to protect against compression‐induced cell ferroptosis during intervertebral disc degeneration

Xinghuo Wu, Wenbin Hua, Shuai Li, 2022, Cell proliferation.

MicroRNA‐132 upregulation promotes matrix degradation in intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2017, Experimental cell research.

Diagnosis and management of intraspinal tuberculoma with giant paraspinal abscesses.

Xinghuo Wu, Xiaodan Zheng, 2019, World neurosurgery.

Clinical result of structural augmentation with cannulated bone screws for the treatment of osteonecrosis of the femoral head

Xinghuo Wu, Xianzhe Liu, Cao Yang, 2009, Orthopaedic Surgery.

The involvement of regulated in development and DNA damage response 1 (REDD1) in the pathogenesis of intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2018, Experimental cell research.

Surgical strategies for the treatment of os odontoideum with atlantoaxial dislocation.

K. Wood, Xinghuo Wu, Shuai Li, 2017, Journal of neurosurgery. Spine.

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy

Xinghuo Wu, Kun Wang, Shuai Li, 2020, Cell Death & Disease.

Spinal surgery and related management on patients with COVID-19: experience of a regional medical centre in Wuhan

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2020, Bone & joint open.

Clinical effect of modified open-door laminoplasty with preservation of the unilateral paraspinal muscle ligament com-plex in treating ossification of posterior longitudinal ligament of the cervical spine

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2018 .

Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Cellular Physiology and Biochemistry.

Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits.

Xinghuo Wu, Yukun Zhang, Shuhua Yang, 2008, Joint, bone, spine : revue du rhumatisme.

TNF-a mediated inflammatory macrophage polarization contributes to the pathogenesis of steroid-induced osteonecrosis in mice

Xinghuo Wu, Xianzhe Liu, Cao Yang, 2015, International journal of immunopathology and pharmacology.

IL-4 administration exerts preventive effects via suppression of underlying inflammation and TNF-α-induced apoptosis in steroid-induced osteonecrosis

Xinghuo Wu, Z. Ye, C. Yang, 2016, Osteoporosis International.

Mixed Reality Technology–Assisted Orthopedics Surgery Navigation

Shuhua Yang, Xinghuo Wu, Zhewei Ye, 2018, Surgical innovation.

The NLRX1-SLC39A7 complex orchestrates mitochondrial dynamics and mitophagy to rejuvenate intervertebral disc by modulating mitochondrial Zn2+ trafficking.

Xinghuo Wu, Kun Wang, Shuai Li, 2023, Autophagy.