Yukun Zhang

发表

Down-regulation of islet amyloid polypeptide expression induces death of human annulus fibrosus cells via mitochondrial and death receptor pathways.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Biochimica et biophysica acta. Molecular basis of disease.

The efficacy of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis

Wenbin Hua, Yukun Zhang, Cao Yang, 2020, BMC Surgery.

MicroRNA-23a-3p promotes the development of osteoarthritis by directly targeting SMAD3 in chondrocytes.

Kun Wang, Shuai Li, Wei Liu, 2016, Biochemical and biophysical research communications.

Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration.

Xinghuo Wu, Wenbin Hua, Yu Song, 2021, Biomaterials.

Establishment and characterization of a novel osteosarcoma cell line: CHOS

Xianzhe Liu, Yukun Zhang, Cao Yang, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Co-culture of mesenchymal stem cells with umbilical vein endothelial cells under hypoxic condition

Yukun Zhang, B. Zhang, Shuhua Yang, 2012, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Therapeutic perspectives of exosomes in glucocorticoid-induced osteoarthrosis

Shuai Li, Yukun Zhang, Cao Yang, 2022, Frontiers in Surgery.

Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Oxidative medicine and cellular longevity.

Sirtuin 6 prevents matrix degradation through inhibition of the NF‐&kgr;B pathway in intervertebral disc degeneration

Jia Hu, Yukun Zhang, Liang Kang, 2017, Experimental cell research.

Short-term effects of minimally invasive dynamic neutralization system for the treatment of lumbar spinal stenosis

Kun Wang, Wenbin Hua, Shuai Li, 2018, Medicine.

Fibronectin induced ITGβ1/FAK‐dependent apoptotic pathways determines the fate of degenerative NP cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Inflammation.

Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Frontiers in Cell and Developmental Biology.

Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Xinghuo Wu, Kun Wang, Shuai Li, 2021, Oxidative medicine and cellular longevity.

Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Experimental & Molecular Medicine.

Aberrant CpG Islands’ Hypermethylation of ABCB1 in Mesenchymal Stem Cells of Patients with Steroid-associated Osteonecrosis

Wenbin Hua, Xianzhe Liu, Yukun Zhang, 2013, The Journal of Rheumatology.

Cells of Patients with Steroid-associated Osteonecrosis Aberrant CpG Islands ' Hypermethylation of ABCB 1 in Mesenchymal Stem

Wenbin Hua, Xianzhe Liu, Yukun Zhang, 2013 .

Biomechanical Evaluation of Different Surgical Approaches for the Treatment of Adjacent Segment Diseases After Primary Anterior Cervical Discectomy and Fusion: A Finite Element Analysis

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Frontiers in Bioengineering and Biotechnology.

Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

Xinghuo Wu, Wenbin Hua, Yu Song, 2019, Theranostics.

Minimally Invasive Surgery Oblique Lumbar Interbody Debridement and Fusion for the Treatment of Lumbar Spondylodiscitis

Wenbin Hua, Yukun Zhang, Cao Yang, 2020, Orthopaedic surgery.

Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Long non-coding RNA HOTAIR modulates intervertebral disc degenerative changes via Wnt/β-catenin pathway

Xinghuo Wu, Kun Wang, Shuai Li, 2019, Arthritis Research & Therapy.

Icariin Attenuates Interleukin-1β-Induced Inflammatory Response in Human Nucleus Pulposus Cells.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Current pharmaceutical design.

Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Inflammation.

WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2022, Nature Communications.

MicroRNA-15b silencing inhibits IL-1β-induced extracellular matrix degradation by targeting SMAD3 in human nucleus pulposus cells

Kun Wang, Wenbin Hua, Shuai Li, 2017, Biotechnology Letters.

Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, Experimental & Molecular Medicine.

lncRNA HOTAIR upregulates autophagy to promote apoptosis and senescence of nucleus pulposus cells

Kun Wang, Shuai Li, Yu Song, 2020, Journal of cellular physiology.

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells

Xinghuo Wu, Kun Wang, Shuai Li, 2017, Journal of cellular and molecular medicine.

Elevated expression of microRNA-30b in osteoarthritis and its role in ERG regulation of chondrocyte.

Xianzhe Liu, Yukun Zhang, Cao Yang, 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Growth differentiation factor 5 modulation of chondrogenesis of self‐assembled constructs involves gap junction‐mediated intercellular communication

Yukun Zhang, Shuhua Yang, Shunan Ye, 2012, Development, growth & differentiation.

In vitro osteogenesis of human adipose-derived stem cells by coculture with human umbilical vein endothelial cells.

Yukun Zhang, Jian Wang, Shuhua Yang, 2011, Biochemical and biophysical research communications.

Full-Endoscopic Visualized Foraminoplasty and Discectomy Under General Anesthesia in the Treatment of L4-L5 and L5-S1 Disc Herniation.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Spine.

Allicin Attenuated Advanced Oxidation Protein Product-Induced Oxidative Stress and Mitochondrial Apoptosis in Human Nucleus Pulposus Cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2020, Oxidative medicine and cellular longevity.

Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits.

Xinghuo Wu, Yukun Zhang, Shuhua Yang, 2008, Joint, bone, spine : revue du rhumatisme.

Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

W. Liu, Xinghuo Wu, Kun Wang, 2018, Redox biology.

The outcome of eosinophilic granuloma involving unilateral atlantoaxial joint

T. Guo, Kun Wang, Shuai Li, 2017, Medicine.

Methylation of microRNA-129-5P modulates nucleus pulposus cell autophagy by targeting Beclin-1 in intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Oncotarget.

TNF-α Regulates ITGβ1 and SYND4 Expression in Nucleus Pulposus Cells: Activation of FAK/PI3K Signaling

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Inflammation.

Autophagy attenuates compression‐induced apoptosis of human nucleus pulposus cells via MEK/ERK/NRF1/Atg7 signaling pathways during intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Experimental cell research.

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy

Xinghuo Wu, Kun Wang, Shuai Li, 2020, Cell Death & Disease.

The noncoding RNA linc-ADAMTS5 cooperates with RREB1 to protect from intervertebral disc degeneration through inhibiting ADAMTS5 expression.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Clinical science.

Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Oxidative medicine and cellular longevity.

Incidence and risk factors of neurological complications during posterior vertebral column resection to correct severe post-tubercular kyphosis with late-onset neurological deficits: case series and review of the literature

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Journal of Orthopaedic Surgery and Research.

Transpedicular Wedge Resection Osteotomy of the Apical Vertebrae for the Treatment of Severe and Rigid Thoracic Kyphoscoliosis: A Retrospective Study of 26 Cases

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019, Spine deformity.

Total spondylectomy of recurrent giant cell tumors in the cervical spine

Wenbin Hua, Shuai Li, Yukun Zhang, 2018, Medicine.

The efficacy of allograft bone using titanium mesh in the posterior-only surgical treatment of thoracic and thoracolumbar spinal tuberculosis

Wenbin Hua, Yukun Zhang, Cao Yang, 2020, BMC Surgery.

Full-endoscopic discectomy via the interlaminar approach for disc herniation at L4-L5 and L5-S1

Xinghuo Wu, Wenbin Hua, Shuai Li, 2018, Medicine.

Sequential correction using satellite rod for the treatment of severe rigid spinal deformity: a retrospective study of 19 cases

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, European Journal of Medical Research.

Surgical approach and management outcomes for junction tuberculous spondylitis: a retrospective study of 77 patients

Kun Wang, Shuai Li, Wei Liu, 2018, Journal of Orthopaedic Surgery and Research.

Distal adding-on after surgery in Lenke 5C adolescent idiopathic scoliosis: clinical and radiological outcomes

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, BMC Musculoskeletal Disorders.

Transpedicular Wedge Resection Osteotomy of the Apical Vertebrae for the Treatment of Severe and Rigid Thoracic Kyphoscoliosis: A Retrospective Study of 26 Cases.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2019 .

Comparison of Clinical Outcomes Following Lumbar Endoscopic Unilateral Laminotomy Bilateral Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for One-Level Lumbar Spinal Stenosis With Degenerative Spondylolisthesis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2021, Frontiers in Surgery.

Clinical and Radiographic Outcomes of Modified Unilateral Open-door Laminoplasty with Posterior Muscle-Ligament Complex Preservation for Cervical Spondylotic Myelopathy.

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2019, Spine.

Comparison of lumbar endoscopic unilateral laminotomy bilateral decompression and minimally invasive surgery transforaminal lumbar interbody fusion for one-level lumbar spinal stenosis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2020, BMC Musculoskeletal Disorders.

Outcomes of discectomy by using full-endoscopic visualization technique via the interlaminar and transforaminal approaches in the treatment of L5-S1 disc herniation

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Medicine.

Comparison of the Clinical Outcomes of Full‐Endoscopic Visualized Foraminoplasty and Discectomy Versus Microdiscectomy for Lumbar Disc Herniation

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Orthopaedic surgery.

Clinical outcomes of uniportal and biportal lumbar endoscopic unilateral laminotomy for bilateral decompression in patients with lumbar spinal stenosis: A retrospective pair-matched case-control study.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2022, World neurosurgery.

m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency

Xinghuo Wu, Kun Wang, Yu Song, 2022, Clinical and translational medicine.

FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

Kun Wang, Shuai Li, Yu Song, 2021, Oxidative medicine and cellular longevity.

Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Wenbin Hua, 2020, Cell proliferation.

Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

Kun Wang, Shuai Li, Yu Song, 2019, Oxidative medicine and cellular longevity.

Inhibition of microRNA-34a prevents IL-1β-induced extracellular matrix degradation in nucleus pulposus by increasing GDF5 expression

Kun Wang, Shuai Li, Wei Liu, 2016, Experimental biology and medicine.

CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis

Kun Wang, Yu Song, Yukun Zhang, 2020, EBioMedicine.

Human mesenchymal stem cells induced by growth differentiation factor 5: an improved self-assembly tissue engineering method for cartilage repair.

Yukun Zhang, Shuhua Yang, Weihua Xu, 2011, Tissue engineering. Part C, Methods.

A Combination of Granulocyte Colony-Stimulating Factor and Stem Cell Factor Ameliorates Steroid- Associated Osteonecrosis in Rabbits

Xinghuo Wu, Xianzhe Liu, Yukun Zhang, 2008, The Journal of Rheumatology.

Active targeting schemes for nano-drug delivery systems in osteosarcoma therapeutics

Yukun Zhang, Zhangrong Cheng, K. Zhao, 2023, Journal of Nanobiotechnology.

The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration.

Yingle Liu, Xinghuo Wu, Kun Wang, 2017, Laboratory investigation; a journal of technical methods and pathology.

Impaired calcium homeostasis via advanced glycation end products promotes apoptosis through endoplasmic reticulum stress in human nucleus pulposus cells and exacerbates intervertebral disc degeneration in rats

Kun Wang, Shuai Li, Yu Song, 2019, The FEBS journal.

Berberine ameliorates oxidative stress-induced apoptosis by modulating ER stress and autophagy in human nucleus pulposus cells.

Kun Wang, Shuai Li, Yu Song, 2019, Life sciences.

The distinct roles of myosin IIA and IIB under compression stress in nucleus pulposus cells

Xinghuo Wu, Kun Wang, Wenbin Hua, 2021, Cell proliferation.

Comparison of Full-Endoscopic Visualized Unilateral Laminotomy Bilateral Decompression and Minimally Invasive Transforaminal Lumbar Interbody Fusion for One-Level Lumbar Spinal Stenosis

Xinghuo Wu, Wenbin Hua, Shuai Li, 2020 .

Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in human intervertebral disc degeneration.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Gene.

MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells

Kun Wang, Wenbin Hua, Shuai Li, 2017, Oncotarget.

Angiopoietin-2 promotes extracellular matrix degradation in human degenerative nucleus pulposus cells.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, International journal of molecular medicine.

Dysregulated miR-127-5p contributes to type II collagen degradation by targeting matrix metalloproteinase-13 in human intervertebral disc degeneration.

Xinghuo Wu, Kun Wang, Wenbin Hua, 2017, Biochimie.

MicroRNA-7 regulates IL-1β-induced extracellular matrix degeneration by targeting GDF5 in human nucleus pulposus cells.

Kun Wang, Shuai Li, Wei Liu, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Angiopoietin‐like protein 8 expression and association with extracellular matrix metabolism and inflammation during intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Shuai Li, 2019, Journal of cellular and molecular medicine.

Author Correction: WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2022, Nature Communications.

G3BP1 coordinates lysophagy activity to protect against compression‐induced cell ferroptosis during intervertebral disc degeneration

Xinghuo Wu, Wenbin Hua, Shuai Li, 2022, Cell proliferation.

CircCOG8 Downregulation Contributes to the Compression-Induced Intervertebral Disk Degeneration by Targeting miR-182-5p and FOXO3

Kun Wang, Wenbin Hua, Yu Song, 2020, Frontiers in Cell and Developmental Biology.

MicroRNA-16-5p Controls Development of Osteoarthritis by Targeting SMAD3 in Chondrocytes.

Xianzhe Liu, Yukun Zhang, Shuhua Yang, 2015, Current pharmaceutical design.

MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes

Xianzhe Liu, Yukun Zhang, Shuhua Yang, 2014, Experimental & Molecular Medicine.

Emerging tissue engineering strategies for annulus fibrosus therapy.

Yukun Zhang, Zhangrong Cheng, Yuhang Chen, 2023, Acta biomaterialia.

基于二维Nb2C的纳米平台增强声动力抗菌治疗并促进骨修复

Yukun Zhang, Liang Ma, Xiaobo Feng, 2023, Science China Materials.

Two-dimensional Nb2C-based nanoplatform augmented sonodynamic antibacterial therapy and bone regeneration

Yukun Zhang, Liang Ma, Xiaobo Feng, 2023, Science China Materials.

The involvement of regulated in development and DNA damage response 1 (REDD1) in the pathogenesis of intervertebral disc degeneration

Xinghuo Wu, Kun Wang, Yu Song, 2018, Experimental cell research.

Chondrogenic differentiation of mouse bone marrow mesenchymal stem cells induced by cartilage-derived morphogenetic protein-2 in vitro

Yukun Zhang, Shuhua Yang, Weihua Xu, 2007, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Effect of the gap junction blocker 1-heptanol on chondrogenic differentiation of mouse bone marrow mesenchymal stem cells in vitro

Yukun Zhang, Shuhua Yang, Weihua Xu, 2009 .

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy

Xinghuo Wu, Kun Wang, Shuai Li, 2020, Cell Death & Disease.

Spinal surgery and related management on patients with COVID-19: experience of a regional medical centre in Wuhan

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2020, Bone & joint open.

Clinical effect of modified open-door laminoplasty with preservation of the unilateral paraspinal muscle ligament com-plex in treating ossification of posterior longitudinal ligament of the cervical spine

Xinghuo Wu, Wenbin Hua, Yukun Zhang, 2018 .

Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy

Xinghuo Wu, Kun Wang, Wenbin Hua, 2018, Cellular Physiology and Biochemistry.

Experimental osteonecrosis induced by a combination of low-dose lipopolysaccharide and high-dose methylprednisolone in rabbits.

Xinghuo Wu, Yukun Zhang, Shuhua Yang, 2008, Joint, bone, spine : revue du rhumatisme.