P. Nathanielsz

发表

Upregulation of growth signaling and nutrient transporters in cotyledons of early to mid-gestational nutrient restricted ewes.

Y. Ma, M. Zhu, A. B. Uthlaut, 2011, Placenta.

Local paracrine effects of estradiol are central to parturition in the rhesus monkey

P. Nathanielsz, S. Jenkins, J. D. Tame, 1998, Nature Medicine.

Maternal nutrient restriction affects properties of skeletal muscle in offspring

Mei J. Zhu, M. Du, P. Nathanielsz, 2006, The Journal of physiology.

Primate parturition and the role of the maternal circadian system.

P. Nathanielsz, M. Honnebier, P. W. Nathanielsz, 1994, European journal of obstetrics, gynecology, and reproductive biology.

Placental fatty acid transport across late gestation in a baboon model of intrauterine growth restriction

P. Nathanielsz, T. Powell, T. Jansson, 2020, The Journal of physiology.

Development of a 96-well based assay for kinetic determination of catalase enzymatic-activity in biological samples.

P. Oliveira, P. Nathanielsz, L. Grilo, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

The Physiological development of the fetus and newborn

P. Nathanielsz, Colin T. Jones, C. Jones, 1985 .

A novel Brucella isolate in association with two cases of stillbirth in non‐human primates – first report

P. Nathanielsz, J. Ebersole, G. Hubbard, 2009, Journal of medical primatology.

Premature Brain Aging in Baboons Resulting from Moderate Fetal Undernutrition

Christian Gaser, Katja Franke, Robert Dahnke, 2017, Front. Aging Neurosci..

Maternal nutrient restriction during pregnancy and lactation leads to impaired right ventricular function in young adult baboons

P. Nathanielsz, M. Schwab, A. Kuo, 2017, The Journal of physiology.

Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation

O. Witte, C. Rosenfeld, P. Nathanielsz, 2017, Journal of Vascular Research.

REVIEW ARTICLE Why Primate Models Matter

J. Rogers, P. W. Czoty, M. Nader, 2014 .

Why primate models matter

William D Hopkins, Kimberley A Phillips, Shiu-Lok Hu, 2014, American journal of primatology.

Effect of maternal baboon (Papio sp.) dietary mismatch in pregnancy and lactation on post‐natal offspring early life phenotype

P. Nathanielsz, S. Jenkins, Cun Li, 2019, Journal of medical primatology.

Baboons as a model to study genetics and epigenetics of human disease.

D. Nicolella, L. Havill, A. Comuzzie, 2013, ILAR journal.

Sugared water consumption by adult offspring of mothers fed a protein-restricted diet during pregnancy results in increased offspring adiposity: the second hit effect

P. Nathanielsz, M. Martínez-Gómez, E. Zambrano, 2013, British Journal of Nutrition.

Maternal nutrient restriction predisposes ventricular remodeling in adult sheep offspring.

Jun Ren, P. Nathanielsz, S. Ford, 2013, The Journal of nutritional biochemistry.

Sexually Dimorphic Effects of Maternal Nutrient Reduction on Expression of Genes Regulating Cortisol Metabolism in Fetal Baboon Adipose and Liver Tissues

P. Nathanielsz, L. Myatt, Cun Li, 2013, Diabetes.

Maternal obesity accelerates fetal pancreatic beta-cell but not alpha-cell development in sheep: prenatal consequences.

M. Nijland, P. Nathanielsz, B. Hess, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Maternal obesity accelerates fetal pancreatic beta-cell but not alpha-cell development in sheep: prenatal consequences.

M. Nijland, P. Nathanielsz, B. Hess, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Developmental programming of the metabolic syndrome by maternal nutritional imbalance: how strong is the evidence from experimental models in mammals?

Imran Y. Khan, P. Taylor, L. Poston, 2004, The Journal of physiology.

Maternal Undernutrition from Early- to Mid-Gestation Leads to Growth Retardation, Cardiac Ventricular Hypertrophy, and Increased Liver Weight in the Fetal Sheep

T. R. Hansen, M. Nijland, P. Nathanielsz, 2003, Biology of reproduction.

Accelerated aging of reproductive capacity in male rat offspring of protein-restricted mothers is associated with increased testicular and sperm oxidative stress

P. Nathanielsz, F. Larrea, L. Reyes-Castro, 2014, AGE.

Electromyographic activity of the nonpregnant and pregnant sheep uterus.

P. Nathanielsz, R. Harding, E. Poore, 1982, American journal of obstetrics and gynecology.

Initiation of growth of baboon primordial follicles in vitro.

P. Nathanielsz, J. E. Fortune, J. Eppig, 1997, Human reproduction.

Insulin-like growth factors and placental function

P. Nathanielsz, N. Schlabritz-Loutsevitch, Cun Li, 2007 .

The effect of acute maternal hemorrhage on the release of catecholamines in the pregnant ewe and the fetus.

C. Hobel, P. Nathanielsz, R. Artal, 1979, American journal of obstetrics and gynecology.

Enhanced transforming growth factor-beta signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation.

Xu Yan, Mei J. Zhu, M. Du, 2010, American journal of physiology. Endocrinology and metabolism.

Effects of early gestational undernutrition on fetal growth, organ development, and placentomal composition in the bovine.

P. Nathanielsz, B. Hess, S. Ford, 2009, Journal of animal science.

High Branched-Chain Amino Acid Concentrations Are Found in Preterm Baboons Receiving Intravenous Amino Acid Solutions and Mimic Alterations Found in Preterm Infants.

P. Nathanielsz, C. Blanco, Lisa L. McGill-Vargas, 2019, JPEN. Journal of parenteral and enteral nutrition.

Antenatal Synthetic Glucocorticoid Exposure at Human Therapeutic Equivalent Doses Predisposes Middle-Age Male Offspring Baboons to an Obese Phenotype That Emerges With Aging

K. Gerow, P. Nathanielsz, S. Jenkins, 2018, Reproductive Sciences.

Brain Docosahexaenoate Accretion in Fetal Baboons: Bioequivalence of Dietary α-Linolenic and Docosahexaenoic Acids

P. Nathanielsz, J. Winter, J. Brenna, 1997, Pediatric Research.

Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study.

M. C. Huang, P. Nathanielsz, J. Brenna, 2001, Journal of lipid research.

Regulation of prostaglandin endoperoxide H synthase 1 and 2 by estradiol and progesterone in nonpregnant ovine myometrium and endometrium in vivo.

Xiao Hong Ma, P. Nathanielsz, L. Buchwalder, 1997, Endocrinology.

The Influence of Maternal Early to Mid-Gestation Nutrient Restriction on Long Chain Polyunsaturated Fatty Acids in Fetal Sheep

M. Nijland, P. Nathanielsz, S. Ford, 2008, Lipids.

Fetal programming of sexual development and reproductive function

P. Nathanielsz, C. Guzman, E. Zambrano, 2014, Molecular and Cellular Endocrinology.

Maternal undernutrition during early to mid-gestation in the ewe results in altered growth, adiposity, and glucose tolerance in male offspring.

M. Nijland, P. Nathanielsz, B. Hess, 2007, Journal of animal science.

A low maternal protein diet during pregnancy and lactation has sex‐ and window of exposure‐specific effects on offspring growth and food intake, glucose metabolism and serum leptin in the rat

P. Nathanielsz, F. Larrea, E. Zambrano, 2006, The Journal of physiology.

Baggs ewes adapt to maternal undernutrition and maintain conceptus growth by maintaining fetal plasma concentrations of amino acids.

G. Wu, P. Nathanielsz, B. Hess, 2008, Journal of animal science.

Flock differences in the impact of maternal dietary restriction on offspring growth and glucose tolerance in female offspring.

P. Nathanielsz, B. Hess, S. Ford, 2019, Society of Reproduction and Fertility supplement.

Developmental origin of health and disease

P. Nathanielsz, V. Padmanabhan, 2006, The Journal of physiology.

Protein restriction during fetal and neonatal development in the rat alters reproductive function and accelerates reproductive ageing in female progeny

P. Nathanielsz, F. Larrea, C. Guzman, 2006, The Journal of physiology.

Placentomal differentiation may compensate for maternal nutrient restriction in ewes adapted to harsh range conditions.

M. Nijland, P. Nathanielsz, B. Hess, 2006, Journal of animal science.

A maternal low protein diet during pregnancy and lactation in the rat impairs male reproductive development

P. Nathanielsz, R. García-Becerra, F. Larrea, 2005, The Journal of physiology.

Baboon Model for the Study of Nutritional Influences on Pregnancy

M. Nijland, P. Nathanielsz, T. McDonald, 2009 .

Animal models that elucidate basic principles of the developmental origins of adult diseases.

P. Nathanielsz, 2006, ILAR journal.

Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1β

P. Nathanielsz, A. Roman, J. Schreher, 2006 .

Diet reduction to requirements in obese/overfed ewes from early gestation prevents glucose/insulin dysregulation and returns fetal adiposity and organ development to control levels.

P. Nathanielsz, S. Ford, N. Long, 2013, American journal of physiology. Endocrinology and metabolism.

Short Title: Maternal obesity alters cotyledonary vascularity

Mei J. Zhu, P. Nathanielsz, S. Ford, 2010 .

Sexual dimorphism in the fetal cardiac response to maternal nutrient restriction.

Cameron P. Casey, T. Metz, P. Nathanielsz, 2017, Journal of molecular and cellular cardiology.

Z‐band and M‐band titin splicing and regulation by RNA binding motif 20 in striated muscles

W. Guo, P. Mozdziak, P. Nathanielsz, 2018, Journal of cellular biochemistry.

Initiation of parturition in the rabbit by maternal and foetal administration of cortisol: effect of rate and duration of administration: suppression of delivery by progesterone.

P. Nathanielsz, M. Abel, 1973, The Journal of endocrinology.

Lack of effect of antenatal glucocorticoid therapy in the fetal baboon on cerebral cortical glucose transporter proteins

O. Witte, P. Nathanielsz, M. Schwab, 2007, Journal of medical primatology.

Lung Epithelial Cells 1 Secretion β Transforming Growth Factor Protein A 1 and C Variants Induce Latent Lung Fibrosis-associated Surfactant Molecular Bases of Disease :

P. Nathanielsz, C. Garcia, W. Yuan, 2013 .

Lung Fibrosis-associated Surfactant Protein A1 and C Variants Induce Latent Transforming Growth Factor β1 Secretion in Lung Epithelial Cells*

P. Nathanielsz, C. Garcia, W. Yuan, 2013, The Journal of Biological Chemistry.

Poor perinatal growth impairs baboon aortic windkessel function

P. Nathanielsz, A. Kuo, C. Li, 2017, Journal of Developmental Origins of Health and Disease.

Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient restricted baboons and may be a mechanism underlying IUGR.

P. Nathanielsz, Madhulika B. Gupta, T. Jansson, 2020, American journal of physiology. Endocrinology and metabolism.

Betamethasone in the Last Week of Pregnancy Causes Fetal Growth Rtardation but Not Adult Hypertension in Rats

M. Nijland, P. Nathanielsz, T. McDonald, 2003, The Journal of the Society for Gynecologic Investigation: JSGI.

Nonhuman primate breath volatile organic compounds associate with developmental programming and cardio-metabolic status

M. Olivier, M. Nijland, P. Nathanielsz, 2018, Journal of breath research.

Emergence of insulin resistance in juvenile baboon offspring of mothers exposed to moderate maternal nutrient reduction.

A. Comuzzie, P. Nathanielsz, T. McDonald, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

nutrient reduction offspring of mothers exposed to moderate maternal Emergence of insulin resistance in juvenile baboon

A. Comuzzie, P. Nathanielsz, T. McDonald, 2011 .

Antenatal corticosteroids alter insulin signaling pathways in fetal baboon skeletal muscle.

P. Nathanielsz, N. Musi, Alvaro G Moreira, 2014, The Journal of endocrinology.

Overnutrition and maternal obesity in sheep pregnancy alter the JNK‐IRS‐1 signaling cascades and cardiac function in the fetal heart

Jun Ren, Mengwei Zang, Ji Li, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The fetal dilemma: spare the brain and spoil the liver.

M. Hanson, P. Nathanielsz, 2003, The Journal of physiology.

Down-Regulation of Placental Transport of Amino Acids Precedes the Development of Intrauterine Growth Restriction in Maternal Nutrient Restricted Baboons

S. Weintraub, P. Nathanielsz, F. Rosario, 2016, Biology of reproduction.

Perinatal maternal undernutrition does not result in offspring capillary rarefaction in the middle-aged male baboon at rest

P. Nathanielsz, A. Kuo, Cun Li, 2020, Journal of Developmental Origins of Health and Disease.

Intergenerational impact of maternal overnutrition and obesity throughout pregnancy in sheep on metabolic syndrome in grandsons and granddaughters.

P. Nathanielsz, S. Ford, Stephen P. Ford, 2017, Domestic animal endocrinology.

Effect of maternal obesity on fetal and postnatal baboon (Papio species) early life phenotype

K. Gerow, P. Nathanielsz, S. Jenkins, 2018, Journal of medical primatology.

The impact of maternal overnutrition and obesity on hypothalamic-pituitary-adrenal axis response of offspring to stress.

P. Nathanielsz, S. Ford, N. Long, 2012, Domestic animal endocrinology.

Reproductive cycling in adult baboons (Papio species) that were intrauterine growth restricted at birth implies normal fertility but increased psychosocial stress

P. Nathanielsz, S. Jenkins, Cun Li, 2018, Journal of medical primatology.

Influence of moderate maternal nutrition restriction on the fetal baboon metabolome at 0.5 and 0.9 gestation.

B. Koletzko, O. Uhl, P. Nathanielsz, 2016, Nutrition, metabolism, and cardiovascular diseases : NMCD.

From Mice to Men: research models of developmental programming.

P. Nathanielsz, C. Rabadan-Diehl, C. Rabadán-Diehl, 2013, Journal of developmental origins of health and disease.

Maternal nutrient restriction alters gene expression in the ovine fetal heart

T. R. Hansen, M. Nijland, P. Nathanielsz, 2004, The Journal of physiology.

Interventions to prevent adverse fetal programming due to maternal obesity during pregnancy.

P. Nathanielsz, S. Ford, L. Reyes-Castro, 2013, Nutrition reviews.

RAPID REPORT: Dietary intervention prior to pregnancy reverses metabolic programming in male offspring of obese rats

P. Nathanielsz, E. Zambrano, G. L. Rodríguez-González, 2010, The Journal of physiology.

Dietary 18:3n-3 and 22:6n-3 as sources of 22:6n-3 accretion in neonatal baboon brain and associated organs

Xiao Hong Ma, M. Mirmiran, P. Nathanielsz, 2007, Lipids.

Mechanisms by which maternal obesity programs offspring for obesity: evidence from animal studies.

P. Nathanielsz, E. Zambrano, 2013, Nutrition reviews.

Effects of maternal global nutrient restriction on fetal baboon hepatic insulin-like growth factor system genes and gene products.

P. Nathanielsz, V. Han, T. McDonald, 2009, Endocrinology.

Three weekly courses of betamethasone administered to pregnant baboons at 0.6, 0.65, and 0.7 of gestation alter fetal and maternal lymphocyte populations at 0.95 of gestation.

P. Nathanielsz, D. Dudley, S. Jenkins, 2006, Journal of reproductive immunology.

Changes in heat shock protein-90 and -70 messenger ribonucleic acid in uterine tissues of the ewe in relation to parturition and regulation by estradiol and progesterone.

P. Nathanielsz, J. Derks, W. Wu, 1996, Endocrinology.

Optimization of Imputation Strategies for High-Resolution Gas Chromatography–Mass Spectrometry (HR GC–MS) Metabolomics Data

M. Olivier, P. Nathanielsz, Kip D. Zimmerman, 2022, Metabolites.

Influence of gestational overfeeding on myocardial proinflammatory mediators in fetal sheep heart.

Jun Ren, P. Nathanielsz, S. Ford, 2013, The Journal of nutritional biochemistry.

Maternal obesity induces sustained inflammation in both fetal and offspring large intestine of sheep

Xu Yan, Mei J. Zhu, M. Du, 2011, Inflammatory bowel diseases.

Maternal obesity downregulates myogenesis and beta-catenin signaling in fetal skeletal muscle.

J. Tong, Xu Yan, Mei J. Zhu, 2009, American journal of physiology. Endocrinology and metabolism.

Postnatal persistence of sex-dependent renal developmentally programmed structural and molecular changes in nonhuman primates

M. Nijland, P. Nathanielsz, R. Shade, 2020, bioRxiv.

A decline in female baboon hypothalamo-pituitary-adrenal axis activity anticipates aging

K. Gerow, A. Comuzzie, P. Nathanielsz, 2017, Aging.

Effects of maternal stress and nutrient restriction during gestation on offspring neuroanatomy in humans

O. Witte, K. Franke, P. Nathanielsz, 2020, Neuroscience & Biobehavioral Reviews.

Production of premature delivery in pregnant rhesus monkeys by androstenedione infusion

P. Nathanielsz, C. Lockwood, S. Jenkins, 1996, Nature Medicine.

Reduction of In Vivo Placental Amino Acid Transport Precedes the Development of Intrauterine Growth Restriction in the Non-Human Primate

P. Nathanielsz, F. Rosario, T. Powell, 2021, Nutrients.

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Guoyao Wu, Y. Kanai, M. Nijland, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Maternal obesity, lipotoxicity and cardiovascular diseases in offspring.

Jun Ren, P. Nathanielsz, S. Ford, 2013, Journal of molecular and cellular cardiology.

Strengths and validity of three methods for assessing rat body fat across the life course

K. Gerow, P. Nathanielsz, M. Menjivar, 2020, International Journal of Obesity.

Levels of corticotropin-releasing hormone messenger ribonucleic acid (mRNA) in the hypothalamic paraventricular nucleus and proopiomelanocortin mRNA in the anterior pituitary during late gestation in fetal sheep.

P. Nathanielsz, M. Grober, D. Myers, 1993, Endocrinology.

Validation of thermal techniques for measurement of pelvic organ blood flows in the nonpregnant sheep: comparison with transit-time ultrasonic and microsphere measurements of blood flow.

P. Nathanielsz, C. Drost, N. J. Randall, 1988, American journal of obstetrics and gynecology.

A heretical view: rather than a solely placental protective function, placental 11β hydroxysteroid dehydrogenase 2 also provides substrate for fetal peripheral cortisol synthesis in obese pregnant ewes

P. Nathanielsz, S. Ford, J. F. Odhiambo, 2020, Journal of Developmental Origins of Health and Disease.

Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta.

Mingyuan Du, M. Du, M. Zhu, 2010, Placenta.

‘Stiffening the sinews of the heart’

P. Nathanielsz, G. Clarke, 2018, The Journal of physiology.

Flock differences in the impact of maternal dietary restriction on offspring growth and glucose tolerance in female offspring.

P. Nathanielsz, B. Hess, S. Ford, 2019, Society of Reproduction and Fertility supplement.

Plasma norepinephrine, epinephrine, and dopamine concentrations in maternal and fetal sheep during spontaneous parturition and in premature sheep during cortisol-induced parturition.

P. Nathanielsz, D. Fisher, T. Glatz, 1981, Endocrinology.

Changes in milk composition in obese rats consuming a high-fat diet

P. Nathanielsz, N. Bobadilla, E. Zambrano, 2015, British Journal of Nutrition.

Multi-generational Impact of Maternal Overnutrition/Obesity in the Sheep on the Neonatal Leptin Surge in Granddaughters

P. Nathanielsz, S. Ford, N. Long, 2014, International Journal of Obesity.

Strength of nonhuman primate studies of developmental programming: review of sample sizes, challenges, and steps for future work.

P. Nathanielsz, S. Jenkins, Cun Li, 2019, Journal of developmental origins of health and disease.

The role of basic science in preventing low birth weight.

P. Nathanielsz, 1995, The Future of children.

Foetal and Neonatal Physiology

K. W. Cross, P. Nathanielsz, K. S. Comline, 1973 .

Role of foetal adrenocorticotrophin during parturition in sheep

P. Nathanielsz, P. Nathanielsz, L. Rees, 1975, Nature.

Responsiveness and maximum secretory capacity of isolated fetal lamb adrenocortical cells throughout the last third of gestation.

P. Nathanielsz, J. Buster, D. Magyar, 1980, Endocrinology.

Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon.

P. Nathanielsz, P. Jeyasuria, E. Albrecht, 2013, Endocrinology.

Pre- and/or postnatal protein restriction developmentally programs affect and risk assessment behaviors in adult male rats

P. Nathanielsz, T. McDonald, L. Reyes-Castro, 2012, Behavioural Brain Research.

Epigenetic modification of fetal baboon hepatic phosphoenolpyruvate carboxykinase following exposure to moderately reduced nutrient availability

M. Nijland, P. Nathanielsz, S. Ford, 2010, The Journal of physiology.

Development of a system for individual feeding of baboons maintained in an outdoor group social environment

P. Nathanielsz, T. McDonald, S. Jenkins, 2004, Journal of medical primatology.

Increased myometrial contracture frequency at 96-140 days accelerates fetal cardiovascular maturation.

N. Shinozuka, P. Nathanielsz, A. Yen, 2000, American journal of physiology. Heart and circulatory physiology.

Effects of antenatal glucocorticoids on cerebral substrate metabolism in the preterm ovine fetus.

P. Nathanielsz, B. Richardson, M. Schwab, 2008, American journal of obstetrics and gynecology.

Effects of maternal nutrient restriction, intrauterine growth restriction, and glucocorticoid exposure on phosphoenolpyruvate carboxykinase‐1 expression in fetal baboon hepatocytes in vitro

P. Nathanielsz, Madhulika B. Gupta, T. Jansson, 2013, Journal of medical primatology.

Elevated glucocorticoids during ovine pregnancy increase appetite and produce glucose dysregulation and adiposity in their granddaughters in response to ad libitum feeding at 1 year of age.

P. Nathanielsz, S. Ford, N. Long, 2013, American journal of obstetrics and gynecology.

Effect of 30 % nutrient restriction in the first half of gestation on maternal and fetal baboon serum amino acid concentrations

Guoyao Wu, M. Nijland, P. Nathanielsz, 2012, British Journal of Nutrition.

Developmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation.

M. G. Ortiz-López, P. Nathanielsz, M. Menjivar, 2012, American journal of physiology. Endocrinology and metabolism.

Emergence of ageing-related changes in insulin secretion by pancreatic islets of male rat offspring of mothers fed a low-protein diet

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2011, British Journal of Nutrition.

Fetal growth in the baboon during the second half of pregnancy

P. Nathanielsz, S. Jenkins, J. D. Tame, 1998, Journal of medical primatology.

Exercise in obese female rats has beneficial effects on maternal and male and female offspring metabolism

P. Nathanielsz, F. Larrea, L. Reyes-Castro, 2013, International Journal of Obesity.

Maternally Administered Dexamethasone at 0.7 of Gestation Suppresses Maternal and Fetal Pituitary and Adrenal Responses to Hypoxemia in Sheep

P. Nathanielsz, T. Coksaygan, M. Kutzler, 2004, Pediatric Research.

2D:4D digit ratio is not a biomarker of developmental programming in baboons (Papio hamadryas species)

P. Nathanielsz, Cun Li, H. Huber, 2018, Journal of medical primatology.

results in altered growth, adiposity, and glucose tolerance in adult offspring Maternal obesity and high nutrient intake before and during gestation in the ewe

A. B. Uthlaut, M. Nijland, P. Nathanielsz, 2013 .

Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring.

A. B. Uthlaut, M. Nijland, P. Nathanielsz, 2010, Journal of animal science.

Evidence for microvascular dysfunction after prenatal dexamethasone at 0.7, 0.75, and 0.8 gestation in sheep.

M. Nijland, P. Nathanielsz, D. Howe, 2002, American journal of physiology. Regulatory, integrative and comparative physiology.

Development of fetal vascular responses to endothelin-1 and acetylcholine in the sheep.

P. Nathanielsz, C. Docherty, J. Kalmar-Nagy, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1.

A. Davenport, M. Nijland, P. Nathanielsz, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

Regional variations in contractile responses to prostaglandins and prostanoid receptor messenger ribonucleic acid in pregnant baboon uterus.

P. Nathanielsz, M. Baguma-Nibasheka, G. C. Smith, 1998, American journal of obstetrics and gynecology.

Paternal line multigenerational passage of altered risk assessment behavior in female but not male rat offspring of mothers fed a low protein diet

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2015, Physiology & Behavior.

Does the umbilical artery systolic/diastolic ratio reflect flow or acidosis? An umbilical artery Doppler study of fetal sheep.

J. Hobbins, P. Nathanielsz, J. Copel, 1990, American journal of obstetrics and gynecology.

Xiao Hong Ma, P. Nathanielsz, W. Wu, 2003, American journal of obstetrics and gynecology.

Intravenous infusion of magnesium sulfate and regional redistribution of fetal blood flow during maternal hemorrhage in late-gestation gravid ewes.

P. Nathanielsz, M. Ramsay, P. Moon, 1999, American journal of obstetrics and gynecology.

Intrauterine asphyxia and the breakdown of physiologic circulatory compensation in fetal sheep.

B. Block, P. Nathanielsz, D. Schlafer, 1990, American journal of obstetrics and gynecology.

Intrauterine growth restriction alters term fetal baboon hypothalamic appetitive peptide balance.

Guoyao Wu, M. Nijland, P. Nathanielsz, 2013, The Journal of endocrinology.

Developmental programming and ageing of male reproductive function

P. Nathanielsz, E. Zambrano, G. L. Rodríguez-González, 2021, European journal of clinical investigation.

Fetal baboon sex specific outcomes in adipocyte differentiation at 0.9 gestation in response to moderate maternal nutrient reduction

R. Krishnapuram, Ursula A White, M. Nijland, 2013, International Journal of Obesity.

Rodent studies of developmental programming and ageing mechanisms

P. Nathanielsz, E. Zambrano, Consuelo Lomas Soria, 2021, European journal of clinical investigation.

Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term.

Y. Ma, P. Nathanielsz, S. Ford, 2011, Domestic animal endocrinology.

Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions

P. Nathanielsz, A. Salmon, Cun Li, 2018, GeroScience.

Multigenerational effects of fetal dexamethasone exposure on the hypothalamic-pituitary-adrenal axis of first- and second-generation female offspring.

P. Nathanielsz, S. Ford, N. Long, 2013, American journal of obstetrics and gynecology.

Growth and insulin dynamics in two generations of female offspring of mothers receiving a single course of synthetic glucocorticoids.

P. Nathanielsz, S. Ford, N. Long, 2012, American journal of obstetrics and gynecology.

Prenatal dexamethasone leads to both endothelial dysfunction and vasodilatory compensation in sheep.

M. Nijland, P. Nathanielsz, D. Howe, 2003, The Journal of physiology.

Prenatal dexamethasone leads to both endothelial dysfunction and vasodilatory compensation in sheep

M. Nijland, P. Nathanielsz, D. Howe, 2003 .

Effect of betamethasone administration to the pregnant baboon at 0.75 gestation on placental eNOS distribution and activity.

J. Wang, X. L. Wang, P. Nathanielsz, 2004, Placenta.

Metformin mitigates the impaired development of skeletal muscle in the offspring of obese mice

J. Tong, M. Du, M. Zhu, 2011, Nutrition & Diabetes.

Area/Moment and Compartmental Modeling of Pharmacokinetics During Pregnancy: Applications to Maternal/Fetal Exposures to Corticosteroids in Sheep and Rats

W. Jusko, P. Nathanielsz, M. Schwab, 2004, Pharmaceutical Research.

Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers

P. Nathanielsz, P. Kievit, E. Sullivan, 2022, Journal of Developmental Origins of Health and Disease.

Bilateral destruction of the fetal paraventricular nuclei prolongs gestation in sheep.

P. Nathanielsz, T. McDonald, P. W. Nathanielsz, 1991, American journal of obstetrics and gynecology.

Corticotropin-releasing hormone-like axons in the adrenal glands of fetal and postnatal sheep.

P. Nathanielsz, T. McDonald, C. Li, 1996, Journal of the autonomic nervous system.

Effects of a Maternal Low Protein Isocaloric Diet on Milk Leptin and Progeny Serum Leptin Concentration and Appetitive Behavior in the First 21 Days of Neonatal Life in the Rat

P. Nathanielsz, F. Larrea, E. Zambrano, 2008, Pediatric Research.

Prenatal Steroid Administration Leads to Adult Pericardial and Hepatic Steatosis in Male Baboons

P. Nathanielsz, M. Schwab, A. Kuo, 2017, International Journal of Obesity.

Postnatal persistence of nonhuman primate sex‐dependent renal structural and molecular changes programmed by intrauterine growth restriction

M. Nijland, P. Nathanielsz, R. Shade, 2022, Journal of medical primatology.

Reply to KN Litwak and S Levin.

T. Q. Bartlett, M. Nijland, P. Nathanielsz, 2014, The American journal of clinical nutrition.

Increased placental XIAP and caspase 3 is associated with increased placental apoptosis in a baboon model of maternal nutrient reduction.

P. Nathanielsz, H. Galan, N. Schlabritz-Loutsevitch, 2010, American journal of obstetrics and gynecology.

Regional blood flow distribution in fetal sheep with intrauterine growth retardation produced by decreased umbilical placental perfusion.

B. Block, P. Nathanielsz, D. Schlafer, 1990, Journal of developmental physiology.

Up-regulation of the fetal baboon hypothalamo-pituitary-adrenal axis in intrauterine growth restriction: coincidence with hypothalamic glucocorticoid receptor insensitivity and leptin receptor down-regulation.

M. Nijland, P. Nathanielsz, T. McDonald, 2013, Endocrinology.

Maternal obesity upregulates fatty acid and glucose transporters and increases expression of enzymes mediating fatty acid biosynthesis in fetal adipose tissue depots.

Mei J. Zhu, M. Zhu, P. Nathanielsz, 2012, Journal of animal science.

Blood pressure and heart rate in the ovine fetus: ontogenic changes and effects of fetal adrenalectomy.

W. P. Smotherman, P. Nathanielsz, N. Unno, 1999, The American journal of physiology.

Regulation of Myometrial Function throughout Gestation and Labor: Effect on Fetal Development

P. Nathanielsz, C. Jansen, T. Cabalum, 1984 .

Effect of abolition of fetal movement on fetal intravascular PO2 and incidence of tonic myometrial contractures in the pregnant ewe at 114 to 134 days' gestation.

P. Nathanielsz, T. Cabalum, H. K. Yu, 1982, American journal of obstetrics and gynecology.

Continuous variability of fetal PO2 in the chronically catheterized fetal sheep.

K. Lowe, P. Nathanielsz, E. Krane, 1979, American journal of obstetrics and gynecology.

Endocrine mechanisms of parturition.

P. Nathanielsz, 1978, Annual review of physiology.

Barbiturate euthanasia solution‐induced tissue artifact in nonhuman primates

S. D. Butler, P. Nathanielsz, G. Hubbard, 2008, Journal of medical primatology.

Differential regulation of prostaglandin EP and FP receptors in pregnant sheep myometrium and endometrium during spontaneous term labor.

P. Nathanielsz, X. Ma, W. Wu, 1999, Biology of reproduction.

Effects of antenatal glucocorticoids on cerebral protein synthesis in the preterm ovine fetus.

P. Nathanielsz, B. Richardson, M. Schwab, 2008, American journal of obstetrics and gynecology.

Inhibition of prostaglandin production by nimesulide is accompanied by changes in expression of the cassette of uterine labor-related genes in pregnant sheep.

Xiao Hong Ma, P. Nathanielsz, N. Unno, 1998, Endocrinology.

Prostaglandin regulation of fetal plasma adrenocorticotropin and cortisol concentrations in late-gestation sheep.

N. Shinozuka, P. Nathanielsz, N. Unno, 1998, Biology of reproduction.

Effect of Maternal Nutrient Restriction in Sheep on the Development of Fetal Skeletal Muscle1

Mei J. Zhu, M. Du, P. Nathanielsz, 2004, Biology of reproduction.

Maternal obesity and overnutrition increase oxidative stress in male rat offspring reproductive system and decrease fertility

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2014, International Journal of Obesity.

Universal DNA Methylation Age Across Mammalian Tissues

Robert W. Williams, S. Horvath, A. Lu, 2021, bioRxiv.

Glucocorticoid exposure of sheep at 0.7 to 0.75 gestation augments late-gestation fetal stress responses.

P. Nathanielsz, M. Schwab, T. Coksaygan, 2012, American journal of obstetrics and gynecology.

Developmental Programming of the Kidney

M. Nijland, P. Nathanielsz, 2009 .

Sexual dimorphism in liver cell cycle and senescence signalling pathways in young and old rats

P. Nathanielsz, E. Zambrano, L. Cox, 2021, The Journal of physiology.

Characterization of decorin mRNA in pregnant intrauterine tissues of the ewe and regulation by steroids.

P. Nathanielsz, J. Derks, N. Unno, 2000, American journal of physiology. Cell physiology.

Effects of betamethasone administration to the fetal sheep in late gestation on fetal cerebral blood flow

P. Nathanielsz, M. Schwab, T. Müller, 2000, The Journal of physiology.

Normal concentrations of essential and toxic elements in pregnant baboons and fetuses (Papio species)

P. Nathanielsz, T. McDonald, S. Jenkins, 2004, Journal of medical primatology.

Age and sex modify cellular proliferation responses to oxidative stress and glucocorticoid challenges in baboon cells

P. Nathanielsz, A. Salmon, Cun Li, 2021, GeroScience.

The nonhuman primate hypothalamo-pituitary-adrenal axis is an orchestrator of programming-aging interactions: role of nutrition.

P. Nathanielsz, E. Zambrano, A. Kuo, 2020, Nutrition reviews.

White monkey syndrome in infant baboons (Papio species)

P. Nathanielsz, T. McDonald, M. Mahaney, 2004, Journal of medical primatology.

Effects of gestational age and cortisol treatment on ovine fetal heart function in a novel biventricular Langendorff preparation

P. Nathanielsz, A. Fowden, D. Giussani, 2005, The Journal of physiology.

Differential Expression of Myometrial Oxytocin Receptor and Prostaglandin H Synthase 2, But Not Estrogen Receptor α and Heat Shock Protein 90 Messenger Ribonucleic Acid in the Gravid Horn and Nongravid Horn in Sheep during Betamethasone-Induced Labor1.

Xiao Hong Ma, N. Shinozuka, T. Yoshizato, 1999, Endocrinology.

Differential expression of myometrial oxytocin receptor and prostaglandin H synthase 2, but not estrogen receptor alpha and heat shock protein 90 messenger ribonucleic acid in the gravid horn and nongravid horn in sheep during betamethasone-induced labor.

N. Shinozuka, T. Yoshizato, P. Nathanielsz, 1999, Endocrinology.

Ductus venosus shunting in marmoset and baboon fetuses

P. Nathanielsz, N. Beindorff, N. Schlabritz-Loutsevitch, 2005, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

Structural evidence for mechanisms to redistribute hepatic and ductus venosus blood flows in nonhuman primate fetuses.

P. Nathanielsz, G. Hubbard, N. Schlabritz-Loutsevitch, 2005, American journal of obstetrics and gynecology.

Resveratrol Supplementation in Obese Pregnant Rats Improves Maternal Metabolism and Prevents Increased Placental Oxidative Stress

P. Taylor, P. Nathanielsz, L. Reyes-Castro, 2022, Antioxidants.

Neonatal adrenocortical function and its possible relation to the uptake of macromolecules by the small intestine of the guinea-pig and rabbit.

R. N. Hardy, P. Nathanielsz, K. Malinowska, 1972, The Journal of endocrinology.

Localization and steroid regulation of prostaglandin E2 receptor protein expression in ovine cervix.

T. Schmitz, P. Nathanielsz, B. Levine, 2006, Reproduction.

Effect of Gestational Age, Corticosteroids, and Birth on Expression of Prostanoid EP Receptor Genes in Lamb and Baboon Ductus Arteriosus

M. Nijland, P. Nathanielsz, W. Wu, 2001, Journal of cardiovascular pharmacology.

Expression of prostanoid receptor genes in baboon chorion and decidua during pregnancy and parturition.

P. Nathanielsz, G. C. Smith, W. Wu, 2001, The Journal of endocrinology.

Changes in Oxytocin Receptor Messenger RNA in the Endometrium, Myometrium, Mesometrium, and Cervix of Sheep in Late Gestation and During Spontaneous and Cortisol-Induced Labor

P. Nathanielsz, W. Wu, W. Wu, 1994, The Journal of the Society for Gynecologic Investigation: JSGI.

Biphasic effect of a prostacyclin methyl ester analog on uterine contractility in the chronically catheterized pregnant rhesus monkey in late gestation.

P. Nathanielsz, M. Honnebier, G. Massmann, 1990, Journal of developmental physiology.

THe relationship between myometrial activity and sleep state and breathing in fetal sheep throughout the last third of gestation.

P. Nathanielsz, R. Harding, E. Poore, 1980, American journal of obstetrics and gynecology.

Behavioral responses of the chronically instrumented sheep fetus to chemosensory stimuli presented in utero.

S. R. Robinson, W. P. Smotherman, P. Nathanielsz, 1995, Behavioral neuroscience.

Temporal structuring of delivery in the absence of a photoperiod: preparturient myometrial activity of the rhesus monkey is related to maternal body temperature and depends on the maternal circadian system.

P. Nathanielsz, S. Jenkins, R. Wentworth, 1991, Biology of reproduction.

Maintaining fetal normoglycemia prevents the increase in myometrial activity and uterine 13,14-dihydro-15-keto-prostaglandin F2 alpha production during food withdrawal in late pregnancy in the ewe.

M. Mitchell, E. Rosen, P. Nathanielsz, 1990, Endocrinology.

Power spectrum analysis of myometrial electromyogram and intrauterine pressure changes in the pregnant rhesus monkey in late gestation.

P. Nathanielsz, R. Wentworth, M. Honnebier, 1989, American journal of obstetrics and gynecology.

Effect of food withdrawal on arterial blood glucose and plasma 13,14-dihydro-15-keto-prostaglandin F2α concentrations and nocturnal myometrial electromyographic activity in the pregnant rhesus monkey in the last third of gestation: A model for preterm labor?

M. Mitchell, P. Nathanielsz, Z. Binienda, 1989 .

The fetus determines circadian oscillation of myometrial electromyographic activity in the pregnant rhesus monkey.

P. Nathanielsz, M. Seron-Ferre, N. Taylor, 1983, American journal of obstetrics and gynecology.

Characterization of the concentration gradient of prostaglandin H synthase 2 mRNA throughout the pregnant baboon uterus.

P. Nathanielsz, G. C. Smith, J. Rose, 2004, The Journal of endocrinology.

A new concept of the significance of regional distribution of prostaglandin H synthase 2 throughout the uterus during late pregnancy: investigations in a baboon model.

P. Nathanielsz, G. C. Smith, S. V. Koenen, 2000, American journal of obstetrics and gynecology.

Prostaglandin dehydrogenase mRNA in baboon intrauterine tissues in late gestation and spontaneous labor.

P. Nathanielsz, G. C. Smith, C. Mecenas, 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

VIP innervation: sharp contrast in fetal sheep and baboon adrenal glands suggests differences in developmental regulation

P. Nathanielsz, T. McDonald, Cun Li, 2000, Brain Research.

Pulmonary phospholipid saturation increases with glucocorticoid receptor mRNAs in late gestation but not due to labor in the fetal rhesus monkey.

P. Nathanielsz, W. Wu, Q. Zhang, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

Topographical specialization of prostaglandin function in late pregnancy and at parturition in the baboon.

P. Nathanielsz, W. Wu, Gordon C.S. Smith, 2004, Prostaglandins, leukotrienes, and essential fatty acids.

Mechanisms linking hypoxia to phosphorylation of insulin‐like growth factor binding protein‐1 in baboon fetuses with intrauterine growth restriction and in cell culture

P. Nathanielsz, Madhulika B. Gupta, T. Jansson, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of pregnancy and obesity on vitamin D status, transport, and metabolism in baboons.

P. Nathanielsz, Cun Li, H. Huber, 2019, American journal of physiology. Endocrinology and metabolism.

Liver mTOR controls IGF-I bioavailability by regulation of protein kinase CK2 and IGFBP-1 phosphorylation in fetal growth restriction.

M. Nijland, P. Nathanielsz, Majida Abu Shehab, 2014, Endocrinology.

DHA Supplementation of Obese Rats throughout Pregnancy and Lactation Modifies Milk Composition and Anxiety Behavior of Offspring

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2021, Nutrients.

Protein restriction in the rat negatively impacts long-chain polyunsaturated fatty acid composition and mammary gland development at the end of gestation.

P. Nathanielsz, M. Rodríguez-Cruz, N. Torres, 2013, Archives of medical research.

Effects of Late Gestational Fetal Exposure to Dexamethasone Administration on the Postnatal Hypothalamus-Pituitary-Adrenal Axis Response to Hypoglycemia in Pigs

P. Nathanielsz, T. Lehmann, M. Schwab, 2017, International journal of molecular sciences.

Neonatal Ovine Adrenal Cortical and Medullary Cell H+ Responses to ACTH and Prostaglandin E2

P. Nathanielsz, T. McDonald, E. Zambrano, 2002, Neonatology.

Prenatal and Postnatal Ovine Adrenal Cell responses to Prostaglandin E2

P. Nathanielsz, T. McDonald, E. Zambrano, 2001, The Journal of the Society for Gynecologic Investigation: JSGI.

Prostaglandin synthase activity of fetal sheep cotyledons at 122 days of gestation and term: expression of prostaglandin synthetic capacity in fetal cotyledonary tissue near labor is location-dependent.

P. Nathanielsz, D. Myers, J. Wimsatt, 1995, Biology of reproduction.

Fetal programming: from gene to functional systems ‐ an overview

P. Nathanielsz, K. Thornburg, 2003 .

Changes in the fetal thyroid axis after induction of premature parturition by low dose continuous intravascular cortisol infusion to the fetal sheep at 130 days of gestation.

P. Nathanielsz, E. Krane, A. L. Thomas, 1978, Endocrinology.

Maternal programming by hypoxia alters the molecular composition of the oviduct of her offspring, the first pathway her grandchildren will transit: a potential novel pathway for intergenerational programming?

P. Nathanielsz, 2019, The Journal of physiology.

A comparative study of vascular responsiveness of myometrial and omental small resistance arteries in late-gestation sheep.

L. Poston, P. Nathanielsz, M. Anwar, 1999, American journal of obstetrics and gynecology.

Docosahexaenoic and arachidonic acid influence on preterm baboon retinal composition and function.

P. Nathanielsz, E. Sarkadi-Nagy, E. Loew, 2003, Investigative ophthalmology & visual science.

Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity

T. Cunha-Oliveira, Cláudia M. Deus, P. Oliveira, 2020, European journal of clinical investigation.

How far upstream or downstream is corticotropin-releasing hormone in the overall process of parturition in rhesus monkeys?

P. Nathanielsz, 1999, American journal of obstetrics and gynecology.

Maternal obesity eliminates the neonatal lamb plasma leptin peak

P. Nathanielsz, S. Ford, N. Long, 2011, The Journal of physiology.

Plasma aldosterone, cortisol and corticosterone concentrations in the new‐born guinea‐pig

P. Nathanielsz, K. Malinowska, 1974, The Journal of physiology.

Androstenedione, testosterone, and estradiol concentrations in fetal and maternal plasma in late pregnancy in the sheep.

P. Nathanielsz, J. Buster, C. Jansen, 1983, Endocrinology.

Regulation of the estrogen receptor and its messenger ribonucleic acid in the ovariectomized sheep myometrium and endometrium: the role of estradiol and progesterone.

P. Nathanielsz, X. Ma, W. Wu, 1996, Biology of reproduction.

Changes in adrenocorticotropin and cortisol responsiveness after repeated partial umbilical cord occlusions in the late gestation ovine fetus.

P. Nathanielsz, N. Unno, D. Giussani, 1997, Endocrinology.

Changes in Adrenocorticotropin and Cortisol Responsiveness after Repeated Partial Umbilical Cord Occlusions in the Late Gestation Ovine Fetus1.

P. Nathanielsz, N. Unno, D. Giussani, 1997, Endocrinology.

Plasma growth hormone concentration in the chronically catheterized ovine fetus during spontaneous term delivery and premature delivery induced by continuous intravascular infusion of low doses of adrenocorticotropin or cortisol to the fetus.

P. Gluckman, K. Lowe, P. Nathanielsz, 1986, American journal of obstetrics and gynecology.

Effect of maternal high-fat diet on key components of the placental and hepatic endocannabinoid system.

P. Nathanielsz, N. Schlabritz-Loutsevitch, G. Ventolini, 2018, American journal of physiology. Endocrinology and metabolism.

Betamethasone-related acute alterations of microtubule-associated proteins in the fetal sheep brain are reversible and independent of age during the last one-third of gestation.

O. Witte, P. Nathanielsz, M. Schwab, 2007, American journal of obstetrics and gynecology.

Effect of fetal and maternal intravascular antipyrine infusion on maternal plasma prostaglandin concentrations in the pregnant sheep at 104 to 127 days' gestation.

M. Mitchell, P. Nathanielsz, J. Figueroa, 1986, American journal of obstetrics and gynecology.

Establishing a Baseline Fetal Ovine Plasma ACTH Value Does Not Require Frequent Sampling: Absence of Significant Peaks of Fetal ACTH Concentration in Plasma in Late Gestation

C. McCulloch, P. Nathanielsz, D. Sadowsky, 1993 .

Stress-induced decrease of uterine blood flow in sheep is mediated by alpha 1-adrenergic receptors

O. Witte, P. Nathanielsz, M. Kiehntopf, 2016, Stress.

Time-trend analysis of plasma cortisol concentrations in the fetal sheep in relation to parturition.

K. Lowe, P. Nathanielsz, J. Buster, 1980, Endocrinology.

The IGF axis in baboon pregnancy: placental and systemic responses to feeding 70% global ad libitum diet.

P. Nathanielsz, V. Han, T. McDonald, 2007, Placenta.

Rapid Communication: Reduced maternal nutrition during early- to mid-gestation elevates newborn lamb plasma cortisol concentrations and eliminates the neonatal leptin surge.

P. Nathanielsz, S. Ford, J. F. Odhiambo, 2018, Journal of animal science.

Opposing Effects of Androgen and Estrogen on Pituitary-Adrenal Function in Nonpregnant Primates1

P. Nathanielsz, S. Jenkins, J. D. Tame, 2000, Biology of reproduction.

Betamethasone effects on fetal sheep cerebral blood flow are not dependent on maturation of cerebrovascular system and pituitary–adrenal axis

O. Witte, P. Nathanielsz, M. Löhle, 2005, The Journal of physiology.

Developmental changes in cerebral autoregulatory capacity in the fetal sheep parietal cortex

P. Nathanielsz, M. Löhle, M. Schwab, 2002, The Journal of physiology.

Fetal exposure to magnesium chloride-adenosine triphosphate (MgCl2-ATP) results in alterations in cerebral blood flow and a metabolic acidosis

P. Nathanielsz, P. Fecci, M. Ramsay, 2001, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Fetal sheep adrenal blood flow responses to hypoxemia after splanchnicotomy using fluorescent microspheres.

P. Nathanielsz, T. McDonald, L. Buchwalder, 1998, Journal of applied physiology.

Bidirectional Placental Transfer of Glucose and Its Turnover in Fetal and Maternal Sheep

P. Nathanielsz, M. Sperling, S. Ganguli, 1979, Pediatric Research.

Formula feeding potentiates docosahexaenoic and arachidonic acid biosynthesis in term and preterm baboon neonates Published, JLR Papers in Press, October 1, 2003. DOI 10.1194/jlr.M300106-JLR200

P. Nathanielsz, E. Sarkadi-Nagy, A. Turpeinen, 2004, Journal of Lipid Research.

Linoleate, alpha-linolenate, and docosahexaenoate recycling into saturated and monounsaturated fatty acids is a major pathway in pregnant or lactating adults and fetal or infant rhesus monkeys.

P. Nathanielsz, D. Giussani, Q. Zhang, 1996, Journal of lipid research.

Integrated Multi-Omics Analysis of Brain Aging in Female Nonhuman Primates Reveals Altered Signaling Pathways Relevant to Age-Related Disorders

C. Shively, S. Puppala, Zeeshan Hamid, 2022, bioRxiv.

Differential effects of natural and synthetic glucocorticoids on cytochrome 17α-hydroxylase (P-45017α) and cytochrome P-450 side-chain cleavage (P-450scc) messenger ribonucleic acid in the sheep placenta

Xiao Hong Ma, P. Nathanielsz, W. Wu, 1999 .

Plasma adrenocorticosteroid concentrations immediately after birth in the rat, rabbit and guineapig

R. N. Hardy, P. Nathanielsz, K. Malinowska, 1972, Experientia.

Endocrine changes during 48 hours of food withdrawal in the pregnant rhesus monkey in the last third of gestation.

P. Nathanielsz, T. Reimers, M. Honnebier, 1989, The Journal of clinical endocrinology and metabolism.

Maternal obesity alters offspring liver and skeletal muscle metabolism in early post‐puberty despite maintaining a normal post‐weaning dietary lifestyle

P. Nathanielsz, Kip D. Zimmerman, H. Huber, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The influence of exogenous steroids on macromolecule uptake by the small intestine of the new‐born rat

R. N. Hardy, P. Nathanielsz, K. Malinowska, 1973, The Journal of physiology.

Effect of the oxytocin antagonist atosiban (1-deamino-2-D-tyr(OET)-4-thr-8-orn-vasotocin/oxytocin) on nocturanl myometrial contractions, maternal cardiovascular function, transplacental passage, and fetal oxygenation in the pregnant baboon during the last third of gestation.

P. Nathanielsz, M. Holland, S. Jenkins, 1997, Biology of reproduction.

The baboon: a model for the study of primate growth hormone receptor gene expression during development.

P. Nathanielsz, G. Hendy, C. Goodyer, 1999, Journal of molecular endocrinology.

Betamethasone effects on ovine uterine and umbilical placental perfusion at the dose used to enhance fetal lung maturation.

P. Nathanielsz, M. Schwab, T. Coksaygan, 2006, American journal of obstetrics and gynecology.

The Influence of Moderate and High Dietary Long Chain Polyunsaturated Fatty Acids (LCPUFA) on Baboon Neonate Tissue Fatty Acids

P. Nathanielsz, J. Brenna, Cun Li, 2007, Pediatric Research.

Activation of cFos in ovine fetal corticotropin-releasing hormone neurons at the time of parturition.

P. Nathanielsz, T. McDonald, G. Hoffman, 1991, Endocrinology.

Failure of bilateral paraventricular nuclear lesions to cause hypothalamic hypothyroidism in fetal sheep.

P. Nathanielsz, T. McDonald, G. Hoffman, 1993, Endocrinology.

Kinetics of Betamethasone and Fetal Cardiovascular Adverse Effects in Pregnant Sheep After Different Doses

W. Jusko, P. Nathanielsz, M. Schwab, 2006, Obstetrics and gynecology.

The effects of betamethasone (BM) on endothelial nitric oxide synthase (eNOS) expression in adult baboon femoral arterial endothelial cells

P. Nathanielsz, J. VandeBerg, Xing-li Wang, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

The effect of prostaglandin E2 infusion in the fetal lamb on fetal plasma ACTH, prolactin and cortisol concentrations.

K. Lowe, P. Nathanielsz, J. Landon, 1979, Prostaglandins.

Sex-Dimorphic Acceleration of Pericardial, Subcutaneous, and Plasma Lipid Increase in Offspring of Poorly Nourished Baboons

A. Comuzzie, P. Nathanielsz, M. Schwab, 2017, International Journal of Obesity.

Maternal protein restriction in pregnancy and/or lactation affects seminiferous tubule organization in male rat offspring

P. Nathanielsz, F. Larrea, E. Zambrano, 2012, Journal of Developmental Origins of Health and Disease.

Growth, Neurobehavioral and Circadian Rhythm Development in Newborn Baboons

Xiao Hong Ma, M. Mirmiran, P. Nathanielsz, 2001, Pediatric Research.

General review of contents by Peter Nathanielsz

P. Nathanielsz, 2021, European journal of clinical investigation.

Life Before Birth: The Challenges of Fetal Development

P. Nathanielsz, 1996 .

A time to be born: implications of animal studies in maternal-fetal medicine.

P. Nathanielsz, 1994, Birth.

Aging endocrine and metabolic phenotypes are programmed by mother's age at conception in a sex dependent fashion in the rat.

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Effect of a 48-hour intravenous delta 4-androstenedione infusion on the pregnant rhesus monkey in the last third of gestation: changes in maternal plasma estradiol concentrations and myometrial contractility.

P. Nathanielsz, M. Honnebier, Z. Binienda, 1989, American journal of obstetrics and gynecology.

Comparative studies on the initiation of labor.

P. Nathanielsz, P. W. Nathanielsz, 1998, European journal of obstetrics, gynecology, and reproductive biology.

Circadian timekeeping during pregnancy: endogenous phase relationships between maternal plasma hormones and the maternal body temperature rhythm in pregnant rhesus monkeys.

P. Nathanielsz, S. Jenkins, M. Honnebier, 1992, Endocrinology.

Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and ventricular size in fetal sheep.

Jun Ren, M. Nijland, P. Nathanielsz, 2008, The Journal of nutritional biochemistry.

Osteochondrosis in fetuses of ewes overfed calcium

P. Nathanielsz, L. Krook, F. Kallfelz, 2007, Calcified Tissue International.

Protein restriction during pregnancy affects maternal liver lipid metabolism and fetal brain lipid composition in the rat.

P. Nathanielsz, F. Larrea, M. Rodríguez-Cruz, 2010, American journal of physiology. Endocrinology and metabolism.

The effects of xylazine on uterine activity, fetal and maternal oxygenation, cardiovascular function, and fetal breathing.

K. Lowe, P. Nathanielsz, C. Jansen, 1984, American journal of obstetrics and gynecology.

The effect of diet and acute starvation on the deiodination of thyroxine and triiodothyronine in the thyroidectomized rat

P. Nathanielsz, 1970, The Journal of physiology.

Variations in plasma thyrotrophin concentration in the neonatal calf and its relationship to circadian periodicity.

P. Nathanielsz, M. Abel, A. L. Thomas, 1974, The Journal of endocrinology.

Plasma thyroxine levels in the young lamb from birth to 61 days.

P. Nathanielsz, 1969, The Journal of endocrinology.

Role of the sympathetic innervation on uterine electromyographic activity in nonpregnant ovariectomized sheep under estrogen supplementation.

P. Nathanielsz, G. Hoffman, G. Massmann, 1992, Biology of reproduction.

Characterization of oxytocin receptor expression and distribution in the pregnant sheep uterus.

P. Nathanielsz, J. Derks, G. Hoffman, 1996, Endocrinology.

Thyroid function in the foetal lamb during the last third of gestation.

P. Nathanielsz, R. Comline, A. L. Thomas, 1973, The Journal of endocrinology.

Cortisol metabolism in the fetal and neonatal sheep.

P. Nathanielsz, R. Comline, M. Silver, 1972, Journal of reproduction and fertility. Supplement.

Fetal body weight and the development of the control of the cardiovascular system in fetal sheep

Martin G. Frasch, O W Witte, O. Witte, 2007, The Journal of physiology.

Plasma adrenocorticotrophin concentration during induction of parturition by the intravascular infusion of physiological amounts of cortisol into the sheep foetus.

P. Nathanielsz, L. Rees, A. L. Thomas, 1975, The Journal of physiology.

Plasma cortisol levels in the newborn lamb from birth to 30 days.

P. Nathanielsz, R. Paisey, 1971, The Journal of endocrinology.

The legacy of the Barcroft Symposium 1972

P. Nathanielsz, 2016, The Journal of physiology.

Adrenocortical function in the fetal and newborn alpaca

P. Nathanielsz, J. Sumar, G. W. Smith, 1978 .

Parturition in the cow: endocrine changes in animals with chronically implanted catheters in the foetal and maternal circulations.

P. Nathanielsz, L. Hall, R. Comline, 1974, The Journal of endocrinology.

Abdominal pregnancy in a baboon: a first case report

P. Nathanielsz, T. McDonald, G. Hubbard, 2004, Journal of medical primatology.

Transcriptomal changes and functional annotation of the developing non-human primate choroid plexus

P. Nathanielsz, C. Mallard, C. J. Ek, 2015, Front. Neurosci..

Time-trend analysis of plasma 11-desoxycorticosterone, corticosterone, cortisol, and aldosterone in fetal and maternal sheep during the last 18 days of gestation.

K. Lowe, P. Nathanielsz, J. Buster, 1981, Journal of steroid biochemistry.

BETAMETHASONE PHARMACOKINETICS AFTER TWO PRODRUG FORMULATIONS IN SHEEP: IMPLICATIONS FOR ANTENATAL CORTICOSTEROID USE

W. Jusko, P. Nathanielsz, M. Samtani, 2005, Drug Metabolism and Disposition.

Maternal intravenous administration of long chain n-3 polyunsaturates to the pregnant ewe in late gestation results in specific inhibition of prostaglandin h synthase (PGHS) 2, but not PGHS1 and oxytocin receptor mRNA in myometrium during betamethasone-induced labor.

Xiao Hong Ma, P. Nathanielsz, W. Wu, 2000 .

Maternal Intravenous Administration of Long Chain N-3 Polyunsaturates to the Pregnant Ewe in Late Gestation Results in Specific Inhibition of Prostaglandin H Synthase (PGHS) 2, but not PGHS1 and Oxytocin Receptor mRNA in Myometrium During Betamethasone-Induced Labor

Xiao Hong Ma, P. Nathanielsz, W. Wu, 2000, The Journal of the Society for Gynecologic Investigation: JSGI.

Delay of preterm delivery in sheep by omega-3 long-chain polyunsaturates.

P. Nathanielsz, M. Baguma-Nibasheka, J. Brenna, 1999, Biology of reproduction.

Effect of bilateral lesions of the ovine fetal hypothalamic paraventricular nuclei at 118-122 days of gestation on subsequent adrenocortical steroidogenic enzyme gene expression.

P. Nathanielsz, T. McDonald, D. Myers, 1992, Endocrinology.

Adrenocorticotrophin-related peptides in adult and foetal sheep pituitary glands.

T. Chard, J. Hope, P. Nathanielsz, 1979, The Journal of endocrinology.

The Fetal Thyroid

P. Nathanielsz, A. L. Thomas, 1983 .

The development of adrenocorticotrophin-sensitive adenylate cyclase activity in the foetal rabbit adrenal: a correlated biochemical and morphological study.

B. Brown, P. Nathanielsz, R. Gould, 1976, The Journal of endocrinology.

Induction of parturition in sheep by low dose intrafetal infusion of synthetic adrenocorticotropin-(1-24) at 120-130 days gestation.

P. Nathanielsz, J. Buster, C. Jansen, 1982, Endocrinology.

Cell Type-Specific Regulation of Fetal Fibronectin Expression in Amnion: Conservation of Glucocorticoid Responsiveness in Human and Nonhuman Primates1

P. Nathanielsz, C. Lockwood, S. Guller, 2000, Biology of reproduction.

A first case of hepatocellular carcinoma in the baboon (Papio spp.) placenta

P. Nathanielsz, G. Hubbard, E. Dick, 2018, Journal of medical primatology.

Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon.

P. Nathanielsz, H. Su, T. Corso, 1999, Journal of lipid research.

Bioequivalence of Dietary α-Linolenic and Docosahexaenoic Acids as Sources of Docosahexaenoate Accretion in Brain and Associated Organs of Neonatal Baboons

Xiao Hong Ma, M. Mirmiran, P. Nathanielsz, 1999, Pediatric Research.

Accelerated aging of reproductive capacity in male rat offspring of protein-restricted mothers is associated with increased testicular and sperm oxidative stress

P. Nathanielsz, F. Larrea, L. Reyes-Castro, 2014, AGE.

glucocorticoid: implications for energy homeostasis Regulation of hypothalamic gene expression by

A. Comuzzie, Y. Nishida, P. Nathanielsz, 2015 .

Biochemical and white blood cell profiles of baboon neonates consuming formulas with moderate and high dietary long‐chain polyunsaturated fatty acids

P. Nathanielsz, J. Anthony, J. Thomas Brenna, 2008, Journal of medical primatology.

Ontogeny of hematological cell and biochemical profiles in maternal and fetal baboons (Papio species)

L. Havill, P. Nathanielsz, T. McDonald, 2005, Journal of medical primatology.

Maternal obesity accelerates rat offspring metabolic ageing in a sex‐dependent manner

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2019, The Journal of physiology.

The influence of moderate and high levels of long chain polyunsaturated fatty acid (LCPUFA) supplementation on 12 week old baboon neonate tissue fatty acids

P. Nathanielsz, J. Anthony, D. Diersen-Schade, 2006 .

The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system

P. Nathanielsz, E. Sarkadi-Nagy, J. Brenna, 2015 .

The Influence of Prematurity and Long Chain Polyunsaturate Supplementation in 4-Week Adjusted Age Baboon Neonate Brain and Related Tissues

P. Nathanielsz, E. Sarkadi-Nagy, A. Turpeinen, 2003, Pediatric Research.

Feto-placental adaptations to maternal obesity in the baboon.

P. Higgins, A. Comuzzie, P. Nathanielsz, 2009, Placenta.

The Prolonged Effect of Repeated Maternal Glucocorticoid Exposure on the Maternal and Fetal Leptin/Insulin-like Growth Factor Axis in Papio species

A. Comuzzie, P. Nathanielsz, S. Ford, 2009, Reproductive Sciences.

Glucocorticoid exposure at the dose used clinically alters cytoskeletal proteins and presynaptic terminals in the fetal baboon brain

Matthias Schwab, Peter W Nathanielsz, P. Nathanielsz, 2003, The Journal of physiology.

Phenotypic changes associated with advancing gestation in maternal and fetal baboon lymphocytes.

P. Nathanielsz, T. McDonald, D. Dudley, 2004, Journal of reproductive immunology.

Maternal obesity impairs fetal cardiomyocyte contractile function in sheep

Jun Ren, W. Guo, P. Nathanielsz, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Fetal programming of skeletal muscle development in ruminant animals.

J. Tong, M. Du, M. Zhu, 2010, Journal of animal science.

Placental amino acid transport and placental leptin resistance in pregnancies complicated by maternal obesity.

P. Nathanielsz, D. Dudley, S. Jenkins, 2010, Placenta.

and Hypertension Report of the National Heart, Lung, and Blood Institute Working Group on Epigenetics

A. Baccarelli, J. Nadeau, D. Harrison, 2012 .

Growth hormone-related genes from baboon (Papio hamadryas): Characterization, placental expression and evolutionary aspects.

S. Cole, A. Comuzzie, P. Nathanielsz, 2010, Gene.

Prenatal origins of adult disease

M. Nijland, P. Nathanielsz, S. Ford, 2008, Current opinion in obstetrics & gynecology.

Organ and gestational age effects of maternal nutrient restriction on global methylation in fetal baboons

M. Szyf, P. Nathanielsz, L. Cox, 2009, Journal of medical primatology.

Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation

P. Nathanielsz, F. Larrea, C. Guzman, 2005, The Journal of physiology.

Hypothalamic paraventricular nuclear lesions delay corticotroph maturation in the fetal sheep anterior pituitary.

P. Nathanielsz, T. McDonald, G. Hoffman, 1992, Endocrinology.

Effect of placement of dexamethasone adjacent to the ovine fetal paraventricular nucleus on adrenocortical steroid hydroxylase messenger ribonucleic acid.

P. Nathanielsz, T. McDonald, D. Myers, 1992, Endocrinology.

Hypothalamic glucocorticoid implants prevent fetal ovine adrenocorticotropin secretion in response to stress.

P. Nathanielsz, T. McDonald, D. Myers, 1990, Endocrinology.

The effect of hypothalamic paraventricular nuclear lesions placed at 108-110 days gestational age on plasma ACTH concentrations in the fetal sheep.

P. Gluckman, P. Nathanielsz, T. McDonald, 1988, Journal of developmental physiology.

Periconceptional nutrient restriction in the ewe alters MAPK/ERK1/2 and PI3K/Akt growth signaling pathways and vascularity in the placentome.

M. Du, M. Zhu, P. Nathanielsz, 2007, Placenta.

Imprinted lncRNA Dio3os preprograms intergenerational brown fat development and obesity resistance

P. Nathanielsz, Mei-Jun Zhu, Qiyuan Yang, 2021, Nature Communications.

Maternal Obesity Enhances Collagen Accumulation and Cross-Linking in Skeletal Muscle of Ovine Offspring

Xu Yan, M. Du, P. Nathanielsz, 2012, PloS one.

Maternal Obesity-Impaired Insulin Signaling in Sheep and Induced Lipid Accumulation and Fibrosis in Skeletal Muscle of Offspring1

Xu Yan, Mei J. Zhu, M. Du, 2011, Biology of reproduction.

Maternal nutrient restriction in the ewe from early to midgestation programs reduced steroidogenic enzyme expression and tended to reduce progesterone content of corpora lutea, as well as circulating progesterone in nonpregnant aged female offspring

P. Nathanielsz, S. Ford, W. Murdoch, 2013, Reproductive Biology and Endocrinology.

Erythrocyte enzymes in sheep: comparison of activity in fetal, newborn, maternal and nonpregnant ewe erythrocytes.

P. Nathanielsz, N. Noble, K. Tanaka, 1982, Biology of the neonate.

AMP‐activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over‐nourished sheep

J. Tong, Mei J. Zhu, M. Du, 2008, The Journal of physiology.

Report on the IASO Stock Conference 2006: early and lifelong environmental epigenomic programming of metabolic syndrome, obesity and type II diabetes

C. Junien, P. Nathanielsz, 2007, Obesity reviews : an official journal of the International Association for the Study of Obesity.

Ontogeny of Angiotensin II Type 1 Receptor and Cytochrome P450c11 in the Sheep Adrenal Gland1

P. Nathanielsz, I. Bird, D. Myers, 2000, Biology of reproduction.

Effect of implantation of dexamethasone adjacent to the paraventricular nucleus on messenger ribonucleic acid for corticotropin-releasing hormone and proopiomelanocortin during late gestation in fetal sheep.

P. Nathanielsz, T. McDonald, D. Myers, 1992, Endocrinology.

Effect of fetal adrenalectomy on messenger ribonucleic acid for proopiomelanocortin in the anterior pituitary and for corticotropin-releasing hormone in the paraventricular nucleus of the ovine fetus.

P. Nathanielsz, D. Myers, X. Y. Ding, 1991, Endocrinology.

Differential Effects of Betamethasone and Dexamethasone Fetal Administration of Parturition in Sheep

P. Nathanielsz, G. Hammond, J. Derks, 1996, The Journal of the Society for Gynecologic Investigation: JSGI.

Effect of Pulsatile Oxytocin Administration to the Pregnant Ewe in the Last Third of Gestation on Fetal ACTH and Cortisol Response to Acute Hypoxemia

P. Nathanielsz, S. Jenkins, D. Sadowsky, 1995, The Journal of the Society for Gynecologic Investigation: JSGI.

Immunocytochemical distribution of androgen receptors in the hypothalamus and pituitary of the fetal baboon in late gestation.

P. Nathanielsz, T. McDonald, S. S. Wu, 1995, Brain research. Developmental brain research.

Effect of Pulsatile Intravenous Oxytocin Administration to Pregnant Sheep Over the Last Third of Gestation on Fetal ACTH and Cortisol Responses to Hypotension

P. Nathanielsz, D. Sadowsky, J. Owiny, 1995, The Journal of the Society for Gynecologic Investigation: JSGI.

Neuropeptide cells and fibers in the hypothalamus and pituitary of the fetal sheep: comparison of oxytocin and arginine vasopressin.

P. Nathanielsz, T. McDonald, G. Hoffman, 1989, Neuroendocrinology.

Antenatal glucocorticoids reset the level of baseline and hypoxemia-induced pituitary-adrenal activity in the sheep fetus during late gestation.

Xiao Hong Ma, P. Nathanielsz, A. Fowden, 2004, American journal of physiology. Endocrinology and metabolism.

Maternal Obesity in Sheep Increases Fatty Acid Synthesis, Upregulates Nutrient Transporters, and Increases Adiposity in Adult Male Offspring after a Feeding Challenge

P. Nathanielsz, S. Ford, N. Long, 2015, PloS one.

A genome resource to address mechanisms of developmental programming: determination of the fetal sheep heart transcriptome

Laura A Cox, Peter W Nathanielsz, M. Nijland, 2012, The Journal of physiology.

Maternal nutrient restriction upregulates growth signaling pathways in the cotyledonary artery of cow placentomes.

M. Du, M. Zhu, P. Nathanielsz, 2007, Placenta.

Early maternal undernutrition programs increased feed intake, altered glucose metabolism and insulin secretion, and liver function in aged female offspring.

A. B. Uthlaut, P. Nathanielsz, S. Ford, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Maternal nutrient restriction during early to mid gestation up-regulates cardiac insulin-like growth factor (IGF) receptors associated with enlarged ventricular size in fetal sheep.

C. Fang, Jun Ren, M. Nijland, 2005, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Maternal Nutrient Restriction Reduces Concentrations of Amino Acids and Polyamines in Ovine Maternal and Fetal Plasma and Fetal Fluids1

Guoyao Wu, T. Spencer, M. Nijland, 2004, Biology of reproduction.

Ultrastructural changes in the placenta of the ewe after fetal pituitary stalk section.

D. H. Steven, P. Nathanielsz, E. Krane, 1978, Quarterly journal of experimental physiology and cognate medical sciences.

Contractile activity of the uterus prior to labor alters the temporal organization of spontaneous motor activity in the fetal sheep.

W. P. Smotherman, P. Nathanielsz, S. Robertson, 1996, Developmental psychobiology.

Methods of Recording Myometrial Activity In Vivo

P. Nathanielsz, M. Honnebier, 1992 .

Thyroid function in the fetus and newborn mammal.

P. Nathanielsz, 1975, British medical bulletin.

Distribution of arachidonic, eicosapentaenoic, docosahexaenoic and related fatty acids in ovine endometrial phospholipids in late gestation and labor.

P. Nathanielsz, W. Wu, Q. Zhang, 1995, Prostaglandins, leukotrienes, and essential fatty acids.

Ultrastructural observations on the placenta of the alpaca (Lama pacos).

D. H. Steven, G. Burton, P. Nathanielsz, 1980, Placenta.

Nutrient Restriction Impairs Nephrogenesis in a Gender-Specific Manner in the Ovine Fetus

M. Nijland, P. Nathanielsz, S. Ford, 2007, Pediatric Research.

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

P. Nathanielsz, F. Rosario, T. Powell, 2017, Scientific Reports.

obesityinvolved in the fetal response to maternal Identification and comparative analyses of myocardial

M. Nijland, P. Nathanielsz, K. Grove, 2015 .

Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity.

M. Nijland, P. Nathanielsz, L. Myatt, 2013, Physiological genomics.

Significant utilization of dietary arachidonic acid is for brain adrenic acid in baboon neonates.

P. Nathanielsz, J. Brenna, P. Lawrence, 2002, Journal of lipid research.

A circadian rhythm in the disappearance of thyroxine from the blood in the calf and the thyroidectomized rat

P. Nathanielsz, 1969, The Journal of physiology.

Plasma tri-iodothyronine concentration in the foetal and newborn lamb.

P. Nathanielsz, R. Comline, M. Silver, 1973, The Journal of endocrinology.

Ultrastructural studies of the rabbit placenta in the last third of gestation.

P. Nathanielsz, P. M. Jack, C. Samuel, 1975, Journal of reproduction and fertility.

Leukocytic Invasion of the Ovine Cervix at Parturition

P. Nathanielsz, R. Gilbert, J. Owiny, 1995, The Journal of the Society for Gynecologic Investigation: JSGI.

Role of catecholamines in maternal-fetal stress transfer in sheep.

Otto W. Witte, Michael Kiehntopf, Sven Rupprecht, 2015, American journal of obstetrics and gynecology.

Effect of long-term bromocriptine infusion on plasma prolactin and ovine chorionic somatomammotropin in the pregnant ewe and fetal sheep.

P. Gluckman, K. Lowe, P. Nathanielsz, 1979, American journal of obstetrics and gynecology.

Effects of Maternally Administered Dexamethasone and Acute Hypoxemia at 0.7 Gestation on Blood Pressure and Placental Perfusion in Sheep

P. Nathanielsz, T. Coksaygan, M. Kutzler, 2004, Hypertension in pregnancy.

Effect of Salmonella endotoxin administered to the pregnant sheep at 133-142 days gestation on fetal oxygenation, maternal and fetal adrenocorticotropic hormone and cortisol, and maternal plasma tumor necrosis factor alpha concentrations.

P. Nathanielsz, G. Foley, D. Schlafer, 1994, Biology of reproduction.

Modification of maternal and fetal oxygenation with the use of tracheal gas infusion.

P. Nathanielsz, J. Figueroa, E. Poore, 1986, American journal of obstetrics and gynecology.

Level of postoperative analgesia is a critical factor in regulation of myometrial contractility after laparotomy in the pregnant baboon: implications for human fetal surgery.

P. Nathanielsz, J. D. Tame, D. Giussani, 1999, American journal of obstetrics and gynecology.

Fetal Oxygen Content is Restored After Maternal Hemorrhage and Fluid Replacement with Polymerized Bovine Hemoglobin, but Not with Hetastarch, in Pregnant Sheep

H. Erb, P. Nathanielsz, S. Bliss, 2001, Anesthesia and analgesia.

Characterization of mammary epithelial stem/progenitor cells and their changes with aging in common marmosets

Luzhe Sun, S. Tardif, P. Nathanielsz, 2016, Scientific Reports.

Effect of 48-hour infusion of the synthetic oxytocin antagonist, [1-beta-mercapto(beta-(CH2)5)1(OMe)Tyr2,Orn8]-oxytocin, on myometrial activity of pregnant sheep at 139-140 days of gestation.

M. Mitchell, P. Nathanielsz, J. Owiny, 1992, Biology of reproduction.

Thyroxine utilization in the new‐born lamb

P. Nathanielsz, 1970, Journal of Physiology.

Effect of synthetic thyrotrophin releasing hormone on thyrotrophin and prolactin concentractions in the peripheral plasma of the pregnant ewe, lamb fetus and neonatal lamb.

P. Nathanielsz, J. Manns, A. L. Thomas, 1975, Biology of the neonate.

Plasma adrenocorticosteroid changes during thyroxine-induced accelerated maturation of the neonatal rat intestine

R. N. Hardy, P. Nathanielsz, K. Malinowska, 2005, Experientia.

Cortisol turnover in the sheep foetus immediately prior to parturition.

P. Nathanielsz, R. Comline, M. Silver, 1970, The Journal of physiology.

Passage of thyroxine across the placenta in the foetal sheep.

P. Nathanielsz, R. Comline, M. Silver, 1970, The Journal of physiology.

Peripheral utilization of thyroxine by the young growing calf.

P. Nathanielsz, 1969, The Journal of physiology.

Parturition in Small Mammals

P. Nathanielsz, J. Challis, 1979 .

Animal models in fetal medicine

P. Nathanielsz, 1980 .

Initiation of parturition in the rabbit by intra-aortic infusion of prostaglandin F 2 .

P. Nathanielsz, M. Abel, G. W. Smith, 1972, The Journal of endocrinology.

A comparison of the luteolytic effect of PGF2alpha and cortisol in the pregnant rabbit.

P. Nathanielsz, J. Taurog, M. Abel, 1973, Prostaglandins.

Pan-primate DNA methylation clocks

S. Horvath, A. Lu, M. Pellegrini, 2020, bioRxiv.

The expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase in ovine maternal uterine and fetal tissues during late gestation and labor.

P. Nathanielsz, W. Wu, Q. Zhang, 1996, Endocrinology.

Myometrial activity and plasma progesterone and oxytocin concentrations in cycling and early-pregnant ewes.

P. Nathanielsz, L. Rhodes, 1990, Biology of reproduction.

Variation in myometrial response to intravenous oxytocin administration at different times of the day in the pregnant rhesus monkey.

P. Nathanielsz, M. Honnebier, J. Figueroa, 1989, Endocrinology.

Characteristics and analysis of uterine electromyographic activity in the pregnant sheep.

P. Nathanielsz, J. Figueroa, E. Poore, 1985, American journal of obstetrics and gynecology.

Validation of a specific radioimmunoassay to measure plasma cortisol in the fetal sheep

P. Nathanielsz, J. Buster, G. Abraham, 1979, Steroids.

Influence of dietary long-chain PUFA on premature baboon lung FA and dipalmitoyl PC composition

P. Nathanielsz, E. Sarkadi-Nagy, J. Brenna, 2003, Lipids.

Efficacy and safety of antenatal steroids.

M. Kemp, A. Jobe, P. Nathanielsz, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

The labeling of pulmonary surfactant phosphatidylcholine in newborn and adult sheep.

A. Jobe, P. Nathanielsz, M. Ikegami, 1981, Experimental lung research.

Proceedings: A dual catheter system for the simultaneous infusion and sampling of the vascular system of the unrestrained rat.

P. Nathanielsz, J. Buckle, 1974, The Journal of physiology.

Characterization of topology-, gestation- and labor-related changes of a cassette of myometrial contraction-associated protein mRNA in the pregnant baboon myometrium.

P. Nathanielsz, X. Ma, W. Wu, 2001, The Journal of endocrinology.

Studies on fetal, neonatal and maternal cortisol metabolism in the mare.

P. Nathanielsz, R. Comline, P. Rossdale, 1975, Journal of reproduction and fertility. Supplement.

Fetal Physiology and Medicine: The Basis of Perinatology

P. Nathanielsz, R. Beard, 1976 .

Intravenous administration of cocaine stimulates gravid baboon myometrium in the last third of gestation

M. Morgan, P. Nathanielsz, S. Jenkins, 1994 .

Maternal obesity disrupts the methionine cycle in baboon pregnancy

Guoyao Wu, M. Nijland, P. Nathanielsz, 2015, Physiological reports.

Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas).

P. Nathanielsz, C. Mallard, C. Ek, 2015, Reproductive toxicology.

Trisomy of chromosome 18 in the baboon (Papio hamadryas anubis)

J. Rogers, P. Nathanielsz, G. Hubbard, 2005, Cytogenetic and Genome Research.

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

P. Nathanielsz, F. Rosario, T. Powell, 2017, Scientific Reports.

Betamethasone-mediated vascular dysfunction and changes in hematological profile in the ovine fetus.

L. Poston, P. Nathanielsz, M. Schwab, 1999, American journal of physiology. Heart and circulatory physiology.

Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring

Daiwen Chen, M. Du, P. Nathanielsz, 2017, The Journal of physiology.

Resveratrol partially prevents oxidative stress and metabolic dysfunction in pregnant rats fed a low protein diet and their offspring

G. Chamorro-Cevallos, P. Nathanielsz, F. Larrea, 2016, The Journal of physiology.

Running title : Maternal resveratrol promotes beige adipogenesis in offspring Resveratrol supplementation to high fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring

Daiwen Chen, Mei J. Zhu, M. Du, 2016 .

Differential Cerebral Cortex Transcriptomes of Baboon Neonates Consuming Moderate and High Docosahexaenoic Acid Formulas

Peter W. Nathanielsz, Joshua C. Anthony, P. Nathanielsz, 2007, PloS one.

Meeting Report on the 3rd International Congress on Developmental Origins of Health and Disease (DOHaD)

Peter Gluckman, David Barker, Diana Kuh, 2007, Pediatric Research.

The non‐human primate kidney transcriptome in fetal development

M. Nijland, P. Nathanielsz, Cun Li, 2018, Journal of medical primatology.

Different Statistical Approaches to Characterization of Adipocyte Size in Offspring of Obese Rats: Effects of Maternal or Offspring Exercise Intervention

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2018, Front. Physiol..

Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation.

P. Oliveira, M. Nijland, P. Nathanielsz, 2015, American journal of physiology. Renal physiology.

Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation

S. Puppala, P. Nathanielsz, S. Gawrieh, 2018, The Journal of physiology.

The insulin-like growth factor system and the fetal brain: Effects of poor maternal nutrition

M. Nijland, P. Nathanielsz, T. McDonald, 2007, Reviews in Endocrine and Metabolic Disorders.

Ontogeny of angiotensin II type 1 receptor (AT1R) in the sheep adrenal gland.

P. Nathanielsz, I. Bird, D. Myers, 1998, Endocrine research.

Increased aggressive and affiliative display behavior in intrauterine growth restricted baboons

T. Q. Bartlett, P. Nathanielsz, S. M. Ford, 2015, Journal of medical primatology.

Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension.

Marcelo Bento Soares, Mingyu Liang, Joseph H Nadeau, 2012, Hypertension.

Down-regulation of growth signaling pathways linked to a reduced cotyledonary vascularity in placentomes of over-nourished, obese pregnant ewes.

M. Du, M. Zhu, M. Nijland, 2009, Placenta.

Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon.

M. Nijland, P. Nathanielsz, F. Rosario, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

Maternal obesity in the ewe increases cardiac ventricular expression of glucocorticoid receptors, proinflammatory cytokines and fibrosis in adult male offspring

P. Nathanielsz, S. Ford, R. McCormick, 2017, PloS one.

Differential distribution of ERalpha and ERbeta mRNA in intrauterine tissues of the pregnant rhesus monkey.

P. Nathanielsz, G. C. Smith, X. Ma, 2000, American journal of physiology. Cell physiology.

Plasma prolactin concentrations in the foetal sheep: normal concentrations before delivery and the effect of cortisol induced delivery

P. Nathanielsz, E. Krane, M. Abel, 1977 .

Intrauterine growth restriction results in persistent vascular mismatch in adulthood

P. Nathanielsz, A. Kuo, Cun Li, 2017, The Journal of physiology.

Vulnerability of the fetal primate brain to moderate reduction in maternal global nutrient availability

Thomas J McDonald, Laura A Cox, Otto W Witte, 2011, Proceedings of the National Academy of Sciences.

Differential distribution of ERα and ERβ mRNA in intrauterine tissues of the pregnant rhesus monkey

Xiao Hong Ma, P. Nathanielsz, W. Wu, 2000 .

Plasma cortisol in the foal during the late fetal and early neonatal period.

P. Nathanielsz, L. Hall, P. Rossdale, 1973, Research in veterinary science.

Fetal endocrinology : an experimental approach

P. Nathanielsz, 1976 .

Effects of glucocorticoids on estrogen receptor messenger ribonucleic acid in the pregnant ovine myometrium in vivo and in vitro.

P. Nathanielsz, J. Derks, W. Wu, 1996, Biology of reproduction.

Changes in estrogen receptor messenger ribonucleic acid in sheep fetal and maternal tissues during late gestation and labor.

P. Nathanielsz, D. Myers, W. Wu, 1995, American journal of obstetrics and gynecology.

Ovine maternal and fetal plasma oxytocin concentrations before and during parturition.

P. Nathanielsz, R. Weitzman, D. Fisher, 1981, Endocrinology.

Metabolic clearance rate and transplacental passage of oxytocin in the pregnant ewe and fetus.

P. Nathanielsz, R. Weitzman, D. Fisher, 1980, Endocrinology.

Plasma Oxytocin Concentrations in the Foetal Sheep

P. Nathanielsz, M. Forsling, B. Kałużewski, 1975 .

Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts.

P. Nathanielsz, K. Kothapalli, J. Brenna, 2013, Prostaglandins, leukotrienes, and essential fatty acids.

Maternal obesity induces fibrosis in fetal myocardium of sheep.

Jun Ren, Xu Yan, Mei J. Zhu, 2010, American journal of physiology. Endocrinology and metabolism.

Life in the Womb: The Origin of Health and Disease

P. Nathanielsz, 1999 .

Electrocortical activity in fetal sheep in the last seven days of gestation

N. Shinozuka, P. Nathanielsz, Norio Shinozuka, 1998, The Journal of physiology.

Thyroid hormone relationships in the fetal and newborn lamb.

B. Brown, P. Nathanielsz, E. Krane, 1980, Biology of the Neonate.

Comparison of a controlled internal drug release device containing progesterone with intravaginal medroxyprogesterone sponges for estrus synchronization in ewes.

P. Nathanielsz, L. Rhodes, 1988, Theriogenology.

In utero exposure to maternal obesity and diabetes: animal models that identify and characterize implications for future health.

P. Taylor, L. Poston, P. Nathanielsz, 2007, Obstetrics and gynecology clinics of North America.

In utero exposure to maternal obesity and diabetes: animal models that identify and characterize implications for future health.

P. Taylor, L. Poston, P. Nathanielsz, 2007, Clinics in perinatology.

Maternal dexamethasone increases endothelin-1 sensitivity and endothelin a receptor expression in ovine foetal placental arteries.

A. Davenport, P. Nathanielsz, R. Kuc, 2003, Placenta.

Effect of moderate, 30 percent global maternal nutrient reduction on fetal and postnatal baboon phenotype

A. Comuzzie, P. Nathanielsz, S. Jenkins, 2017, Journal of medical primatology.

Prostaglandin mediates premature delivery in pregnant sheep induced by estradiol at 121 days of gestational age.

Xiao Hong Ma, P. Nathanielsz, T. Coksaygan, 2004, Endocrinology.

Effects of Gestational Age and Labor on Expression of Prostanoid Receptor Genes in Baboon Uterus1

P. Nathanielsz, W. Wu, Gordon C.S. Smith, 2001, Biology of reproduction.

The role and regulation of corticotropin in the fetal sheep.

P. Nathanielsz, E. Krane, L. Rees, 1977, Ciba Foundation symposium.

The effect of mild hypoxemia maintained for twenty-four hours on maternal and fetal glucose, lactate, cortisol, and arginine vasopressin in pregnant sheep at 122 to 139 days' gestation.

P. Nathanielsz, M. E. Towell, J. Figueroa, 1987, American journal of obstetrics and gynecology.

Maternal Obesity: Influences of maternal obesity on the health of the offspring: a review of animal models

P. Taylor, L. Poston, P. Nathanielsz, 2012 .

Changing patterns of steroid production in the fetus and placenta and their effects on development.

K. Lowe, P. Nathanielsz, J. Buster, 1981, Ciba Foundation symposium.

Comparison of two rapid cortisol radioimmunoassays for use in the fetal sheep

K. Lowe, P. Nathanielsz, J. Buster, 1979, Steroids.

Erythrocyte enzymes in Ovis aries. Effect of cell age.

P. Nathanielsz, N. Noble, K. Tanaka, 1982, Comparative biochemistry and physiology. B, Comparative biochemistry.

Cardiac magnetic resonance imaging: insights into developmental programming and its consequences for aging

P. Nathanielsz, A. Moody, A. Kuo, 2020, Journal of Developmental Origins of Health and Disease.

Metabolic adjustments to moderate maternal nutrient restriction

T. Q. Bartlett, M. Nijland, P. Nathanielsz, 2007, British Journal of Nutrition.

Gene expression profile differences in left and right liver lobes from mid‐gestation fetal baboons: a cautionary tale

M. Nijland, P. Nathanielsz, G. Hubbard, 2006, The Journal of physiology.

Efficacy of Dietary Arachidonic Acid Provided as Triglyceride or Phospholipid as Substrates for Brain Arachidonic Acid Accretion in Baboon Neonates

P. Nathanielsz, Meng-Chuan Huang, J. Brenna, 2002, Pediatric Research.

Maternal obesity has sex‐dependent effects on insulin, glucose and lipid metabolism and the liver transcriptome in young adult rat offspring

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2018, The Journal of physiology.

Up-regulation of Toll-like receptor 4/nuclear factor-kappaB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese sheep at late gestation.

J. Tong, Xu Yan, Mei J. Zhu, 2010, Endocrinology.

Walking speed declines with age in male and female baboons (Papio sp.): Confirmation of findings with sex as a biological variable

K. Gerow, P. Nathanielsz, Cun Li, 2021, Journal of medical primatology.

Sex-Dependent Cognitive Performance in Baboon Offspring Following Maternal Caloric Restriction in Pregnancy and Lactation

Jesse S. Rodriguez, T. Q. Bartlett, M. Nijland, 2012, Reproductive Sciences.

Pregnancy and Lactation Sex-Dependent Cognitive Performance in Baboon Offspring Following Maternal Caloric Restriction in

Peter W. Nathanielsz, Jesse S. Rodriguez, T. Q. Bartlett, 2012 .

Pre- and/or postnatal protein restriction in rats impairs learning and motivation in male offspring

P. Nathanielsz, R. D. Wimmer, F. Larrea, 2011, International Journal of Developmental Neuroscience.

In Vivo Administration of Nimesulide, a Selective PGHS-2 Inhibitor, Increases In Vitro Myometrial Sensitivity to Prostaglandins While Lowering Sensitivity to Oxytocin

P. Nathanielsz, M. Baguma‐Nibasheka, 1998, The Journal of the Society for Gynecologic Investigation: JSGI.

Increased Colocalization and Interaction Between Decidual Protein Kinase A and Insulin-like Growth Factor–Binding Protein-1 in Intrauterine Growth Restriction

P. Nathanielsz, Madhulika B. Gupta, T. Jansson, 2022, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Effects of three courses of maternally administered dexamethasone at 0.7, 0.75, and 0.8 of gestation on prenatal and postnatal growth in sheep.

P. Nathanielsz, T. Coksaygan, M. Kutzler, 2004, Pediatrics.

Modification of myometrial activity in vivo by administration of cyclic nucleotides and theophylline to the pregnant rat.

P. Nathanielsz, J. Buckle, 1975, The Journal of endocrinology.

Characteristics of the electromyogram recorded from the mesometrium of the pregnant ewe from 106 days' gestation to delivery: similarities with and differences from the electromyogram obtained from the myometrium.

P. Nathanielsz, J. Figueroa, A. Massmann, 1987, American journal of obstetrics and gynecology.

Integrated multi-omics analysis of brain aging in female nonhuman primates reveals altered signaling pathways relevant to age-related disorders

C. Shively, M. Baxter, S. Puppala, 2023, Neurobiology of Aging.

Increase in Prostaglandin H Synthase 2, but Not Prostaglandin F2α Synthase mRNA in Intrauterine Tissues During Betamethasone-Induced Premature Labor and Spontaneous Term Labor in Sheep

N. Shinozuka, T. Yoshizato, P. Nathanielsz, 2001, Journal of the Society for Gynecologic Investigation.

Maternal obesity programs reduced leptin signaling in the pituitary and altered GH/IGF1 axis function leading to increased adiposity in adult sheep offspring

P. Nathanielsz, S. Ford, J. F. Odhiambo, 2017, PloS one.

The reduced contraction of baboon Lower Uterine Segment (LUS) to prostaglandin (PG)E is paralleled by increased EP and decreased EP receptor mRNA compared with the fundus

P. Nathanielsz, W. Wu, Gordon C.S. Smith, 1998 .

Alteration of 24-hour rhythms in myometrial activity in the chronically catheterized pregnant rhesus monkey after a 6-hour shift in the light-dark cycle.

P. Nathanielsz, S. Jenkins, M. Honnebier, 1990, American journal of obstetrics and gynecology.

Biologic basis of term and preterm labor.

P. Nathanielsz, D. Myers, 1993, Clinics in perinatology.

Adverse Effects of Antenatal Glucocorticoids on Cerebral Myelination in Sheep

O. Witte, P. Nathanielsz, M. Schwab, 2009, Obstetrics and gynecology.

Importance of the lactation period in developmental programming in rodents.

P. Nathanielsz, E. Zambrano, G. L. Rodríguez-González, 2020, Nutrition reviews.

Maternal activity, anxiety, and protectiveness during moderate nutrient restriction in captive baboons (Papio sp.)

T. Q. Bartlett, M. Nijland, P. Nathanielsz, 2018, Journal of medical primatology.

Sex dependent Vulnerability of Fetal Nonhuman Primate Cardiac Mitochondria to Moderate Maternal Nutrient Reduction.

Antonio Vallecillo, P. Oliveira, M. Nijland, 2021, Clinical science.

Dose-response effects of betamethasone on maturation of the fetal sheep lung.

M. Nijland, P. Nathanielsz, S. Ford, 2010, American journal of obstetrics and gynecology.

Prostaglandin E2 Receptor Expression in Fetal Baboon Lung at 0.7 Gestation After Betamethasone Exposure

T. Schmitz, P. Nathanielsz, S. Ford, 2007, Pediatric Research.

Hippocampal mechanisms in impaired spatial learning and memory in male offspring of rats fed a low‐protein isocaloric diet in pregnancy and/or lactation

P. Nathanielsz, G. Quirarte, L. Reyes-Castro, 2018, Hippocampus.

Non‐human primate fetal kidney transcriptome analysis indicates mammalian target of rapamycin (mTOR) is a central nutrient‐responsive pathway

M. Nijland, P. Nathanielsz, G. Hubbard, 2007, The Journal of physiology.

Fetal serum folate concentrations and placental folate transport in obese women.

P. Nathanielsz, T. Powell, T. Jansson, 2011, American journal of obstetrics and gynecology.

Decreased placental amino acid transport and intrauterine growth restriction: which is the chicken and which is the egg?

P. Nathanielsz, 2006, Journal of Physiology.

Moderate Global Reduction in Maternal Nutrition Has Differential Stage of Gestation Specific Effects on β1- and β2-Adrenergic Receptors in the Fetal Baboon Liver

M. Nijland, P. Nathanielsz, T. McDonald, 2011, Reproductive Sciences.

Regional variation in adipogenesis and IGF regulatory proteins in the fetal baboon.

E. Ravussin, C. Conover, P. Nathanielsz, 2009, Biochemical and biophysical research communications.

Influence of gestational overfeeding on cardiac morphometry and hypertrophic protein markers in fetal sheep.

Jun Ren, M. Nijland, P. Nathanielsz, 2011, The Journal of nutritional biochemistry.

Different levels of overnutrition and weight gain during pregnancy have differential effects on fetal growth and organ development

A. B. Uthlaut, P. Nathanielsz, S. Ford, 2010, Reproductive biology and endocrinology : RB&E.

Prenatal betamethasone exposure has sex specific effects in reversal learning and attention in juvenile baboons.

Nicole R. Zürcher, Jesse S. Rodriguez, T. Q. Bartlett, 2011, American journal of obstetrics and gynecology.

CANTAB delayed matching to sample task performance in juvenile baboons

Jesse S. Rodriguez, T. Q. Bartlett, M. Nijland, 2011, Journal of Neuroscience Methods.

Performance of juvenile baboons on neuropsychological tests assessing associative learning, motivation and attention

Nicole R. Zürcher, Kate Keenan, Peter W. Nathanielsz, 2010, Journal of Neuroscience Methods.

Effect of prolactin infusion into the chronically catheterized ovine foetus [proceedings].

K. Lowe, P. Nathanielsz, C. Jansen, 1977, The Journal of endocrinology.

Effect of bilateral splanchnic nerve section on adrenal function in the ovine fetus.

P. Nathanielsz, D. Robertshaw, D. Myers, 1990, Endocrinology.

Maternal obesity and overnutrition alter fetal growth rate and cotyledonary vascularity and angiogenic factor expression in the ewe.

Mei J. Zhu, P. Nathanielsz, S. Ford, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

The frontal cortex IGF system is down regulated in the term, intrauterine growth restricted fetal baboon.

P. Nathanielsz, T. McDonald, M. Schwab, 2013, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Poor nutrition during pregnancy and lactation negatively affects neurodevelopment of the offspring: evidence from a translational primate model.

Kate Keenan, Peter W Nathanielsz, Jesse S. Rodriguez, 2013, The American journal of clinical nutrition.

Expression of the placental transcriptome in maternal nutrient reduction in baboons is dependent on fetal sex.

P. Nathanielsz, T. Jansson, Cun Li, 2013, The Journal of nutrition.

Maternal obesity epigenetically alters visceral fat progenitor cell properties in male offspring mice

M. Du, P. Nathanielsz, Mei-Jun Zhu, 2016, The Journal of physiology.

Blood pressure and heart rate in the ovine fetus: ontogenic changes and effects of fetal adrenalectomy.

W. P. Smotherman, P. Nathanielsz, N. Unno, 1999, American journal of physiology. Heart and circulatory physiology.

Pan-primate DNA methylation clocks

S. Horvath, A. Lu, M. Pellegrini, 2021 .

Maternal obesity downregulates microRNA let-7g expression, a possible mechanism for enhanced adipogenesis during ovine fetal skeletal muscle development

Xu Yan, Mei J. Zhu, M. Du, 2013, International Journal of Obesity.

IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Cα (PKCα)

P. Nathanielsz, Madhulika B. Gupta, T. Jansson, 2021, Molecular and Cellular Endocrinology.

Induction of premature delivery in sheep following infusion of cortisol to the fetus. I. The effect of maternal administration of progestagens.

P. Nathanielsz, J. Buster, G. Jenkin, 1985, Canadian journal of physiology and pharmacology.

fetal baboon kidney gene expression Effect of 30 per cent maternal nutrient restriction from 0.16 to 0.5 gestation on

M. Nijland, P. Nathanielsz, R. Shade, 2007 .

Plasma progestagens and oestrogens in fetus and mother in late pregnancy.

P. Nathanielsz, R. Comline, P. Rossdale, 1975, Journal of reproduction and fertility. Supplement.

Development of responsiveness of dispersed rabbit adrenocortical cells to synthetic adrenocorticotropic hormone [ACTH-(1-24)] and alpha melanocyte-stimulating hormone.

P. Nathanielsz, J. Buster, D. Magyar, 1980, Endocrinology.

Further characterization of the electromyographic activity of the myometrium and mesometrium in nonpregnant sheep under estrogen supplementation.

P. Nathanielsz, G. Massmann, J. Figueroa, 1991, Biology of Reproduction.

Fetal Programming: How the Quality of Fetal Life Alters Biology for a Lifetime

P. Nathanielsz, 2000 .

Adrenocortical hormones and absorption of macromolecules by the small intestine of the young rat.

R. N. Hardy, P. Nathanielsz, K. Malinowska, 1972, The Journal of endocrinology.

Adrenocorticotropin and glucocorticoid concentrations in fetal and maternal plasma of rabbit does continuously infused with cortisol from day 21 to day 24 of gestation.

P. Nathanielsz, J. Buster, D. Magyar, 1979, American journal of obstetrics and gynecology.

Histological observations of the adrenal glands of newborn alpacas (Lama pacos)

P. Nathanielsz, C. Samuel, J. Sumar, 1979 .

Corticotropin-releasing hormone and its receptor distribution in fetal membranes and placenta of the rhesus monkey in late gestation and labor.

P. Nathanielsz, T. McDonald, D. Giussani, 1995, Endocrinology.

Cocaine in pregnancy: the effect of maternal administration of cocaine on the maternal and fetal pituitary-adrenal axes.

P. Nathanielsz, M. Jones, D. Sadowsky, 1991, American Journal of Obstetrics and Gynecology.

In the rhesus monkey placental retention after fetectomy at 121 to 130 days' gestation outlasts the normal duration of pregnancy.

P. Nathanielsz, M. Honnebier, J. Figueroa, 1992, American journal of obstetrics and gynecology.

Effects of repeated administration of cocaine to the fetal sheep in the last days of pregnancy.

P. Nathanielsz, J. Derks, R. Wentworth, 1993, American journal of obstetrics and gynecology.

Research in perinatal medicine

J. Parer, P. Nathanielsz, 1984 .

Intrauterine growth retardation and the circulatory responses to acute hypoxemia in fetal sheep.

B. Block, P. Nathanielsz, D. Schlafer, 1989, American journal of obstetrics and gynecology.

Molecular aspects of placental and fetal membrane autocoids: Rice, G. E. and Brennecke, S. P. (Eds) CRC Press. 1993. 462 pp, £152.00. ISBN 0-8493-6239-3

P. Nathanielsz, 1994 .

Hypothalamic expression of genes for appetite regulators and estrogen α, estrogen β and leptin receptors in obese dams and their fetuses.

P. Nathanielsz, B. Hess, S. Ford, 2011, Animal.

Lipoxygenase gene expression in baboon intrauterine tissues in late pregnancy and parturition.

P. Nathanielsz, G. C. Smith, W. Wu, 2001, Molecular human reproduction.

Sufficient Progesterone-Priming Prior to Estradiol Stimulation Is Required for Optimal Induction of the Cervical Prostaglandin System in Pregnant Sheep at 0.7 Gestations1

P. Nathanielsz, T. Coksaygan, J. Rose, 2005, Biology of reproduction.

Evidence for the Presence of AH 13205-Sensitive EP2-Prostanoid Receptors in the Pregnant Baboon But Not in the Pregnant Sheep Myometrium Near Term

P. Nathanielsz, S. Jenkins, R. A. Coleman, 1995, The Journal of the Society for Gynecologic Investigation: JSGI.

Dynamics of cardiovascular responses to repeated partial umbilical cord compression in late-gestation sheep fetus.

P. Nathanielsz, J. Derks, N. Unno, 1997, American journal of physiology. Heart and circulatory physiology.

Developmental programming of aging of isolated pancreatic islet glucose-stimulated insulin secretion in female offspring of mothers fed low-protein diets in pregnancy and/or lactation

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2012, Journal of Developmental Origins of Health and Disease.

Epigenetic predictors of maximum lifespan and other life history traits in mammals

S. Horvath, J. Gaillard, D. Blumstein, 2021, bioRxiv.

Cardiac remodelling in a baboon model of intrauterine growth restriction mimics accelerated ageing

P. Nathanielsz, Jinqi Li, A. Kuo, 2017, The Journal of physiology.

Changes in prostacyclin synthase in pregnant sheep myometrium, endometrium, and placenta at spontaneous term labor and regulation by estradiol and progesterone.

P. Nathanielsz, X. Ma, W. Wu, 1999, American journal of obstetrics and gynecology.

Ageing changes in biventricular cardiac function in male and female baboons (Papio spp.)

P. Nathanielsz, A. Kuo, Cun Li, 2018, The Journal of physiology.

Cocaine's effect on plasma oxytocin concentrations in the baboon during late pregnancy.

M. Morgan, P. Nathanielsz, C. Mecenas, 1996, American journal of obstetrics and gynecology.

Proteinuric hypertension in a pregnant baboon: Was this pre‐eclampsia?

P. Nathanielsz, J. D. Tame, J. Winter, 1997, Journal of medical primatology.

Variability of Continuously Measured Arterial pH and Blood Gas Values in the Near Term Fetal Lamb

W. Zijlstra, J. Aarnoudse, P. Nathanielsz, 1995, Pediatric Research.

Effect of fetal intravascular 4-aminoantipyrine infusions on myometrial activity (contractures) at 125 to 143 days' gestation in the pregnant sheep.

M. Mitchell, P. Nathanielsz, S. Sunderji, 1984, American journal of obstetrics and gynecology.

Inhibition of arachidonic acid metabolism by antipyrine and 4-aminoantipyrine.

M. Mitchell, P. Nathanielsz, J. Figueroa, 1985, American journal of obstetrics and gynecology.

Effects of Prenatal Stress on Structural Brain Development and Aging in Humans

Otto W. Witte, Katja Franke, Matthias Schwab, 2017, bioRxiv.

Betamethasone in the last week of pregnancy causes fetal growth retardation but not adult hypertension in rats.

M. Nijland, P. Nathanielsz, T. McDonald, 2003, Journal of the Society for Gynecologic Investigation.

Antenatal betamethasone treatment reduces synaptophysin immunoreactivity in presynaptic terminals in the fetal sheep brain

P. Nathanielsz, M. Schwab, U. Sliwka, 2001, Neuroscience Letters.

MRI based biomarker for brain aging in rodents and non-human primates

Matthias Schwab, Christian Gaser, Cun Li, 2016, 2016 International Workshop on Pattern Recognition in Neuroimaging (PRNI).

Blood-Based miRNA Biomarkers as Correlates of Brain-Based miRNA Expression

M. Carless, S. Puppala, P. Nathanielsz, 2022, Frontiers in Molecular Neuroscience.

Alteration of fetal oxygenation and responses to acute hypoxemia by increased myometrial contracture frequency produced by pulse administration of oxytocin to the pregnant ewe from 96 to 131 days' gestation.

N. Shinozuka, P. Nathanielsz, A. Yen, 1999, American journal of obstetrics and gynecology.

The effect of myometrial contractures on uterine blood flow in the pregnant sheep at 114 to 140 days' gestation measured by the 4-aminoantipyrine equilibrium diffusion technique.

P. Nathanielsz, S. Sunderji, J. Figueroa, 1984, American journal of obstetrics and gynecology.

Moderate maternal nutrient reduction in pregnancy alters fatty acid oxidation and RNA splicing in the nonhuman primate fetal liver

P. Nathanielsz, Kip D. Zimmerman, Jeannie Chan, 2023, Journal of Developmental Origins of Health and Disease.

Maternal Under-Nutrition During Pregnancy Alters the Molecular Response to Over-Nutrition in Multiple Organs and Tissues in Juvenile Offspring

S. Puppala, A. Comuzzie, M. Nijland, 2023, bioRxiv.

Printed in U.S.A. Copyright © 1999 by The Endocrine Society Suppression Subtractive Hybridization Identified a Marked Increase in Thrombospondin-1 Associated with Parturition in Pregnant Sheep Myometrium*

P. Nathanielsz, N. Unno, X. Ma, 2022 .

Noninvasive cerebral hemoglobin oxygenation quantification of fetal sheep under hypoxic stress in utero using frequency-domain diffuse optical two-layer model

Britton Chance, Arjun G. Yodh, Regine Choe, 2003, SPIE BiOS.

Induction of premature delivery in sheep following infusion of cortisol to the fetus: the effect of maternal progestagen treatment on the C21-steroid-17 alpha-hydroxylase, C-17,20 lyase and aromatase pathways.

P. Nathanielsz, J. Buster, G. Jenkin, 1988, Journal of developmental physiology.

Time, Tide and the Living Clocks of Marine Organisms

P. Nathanielsz, 1996 .

The Involvement of Innervation in the Regulation of Fetal Adrenal Steroidogenesis

P. Nathanielsz, T. McDonald, 1998, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Comparison of continuous transcutaneous and continuous intravascular PO2 measurement in fetal sheep.

K. Lowe, P. Nathanielsz, C. Jansen, 1980, American journal of obstetrics and gynecology.

A male baboon (Papio hamadryas) with a mosaic 43,XXY/42,XY karyotype

J. Rogers, P. Nathanielsz, J. McCarrey, 2006, American journal of medical genetics. Part A.

Effect of maternal fatness on fetal steroids and semi-quantitative real-time PCR expression of receptor genes in sheep.

P. Nathanielsz, B. Hess, S. Ford, 2009, Animal reproduction science.

Maternal nutrient restriction in baboon programs later-life cellular growth and respiration of cultured skin fibroblasts: a potential model for the study of aging-programming interactions

P. Nathanielsz, A. Salmon, Cun Li, 2018, GeroScience.

Comparison of changes in ovine plasma chorionic somatomammotropin concentrations in the fetus and mother before spontaneous vaginal delivery at term and adrenocorticotropin-induced premature delivery.

P. Gluckman, K. Lowe, P. Nathanielsz, 1984, American journal of obstetrics and gynecology.

Humeral skeletal development and plasma constituent changes in fetuses of ewes maintained on a low calcium diet from 60 days of gestation

P. Nathanielsz, L. Krook, F. Kallfelz, 1993, Calcified Tissue International.

Developmental Programming-Aging Interactions Have Sex-Specific and Developmental Stage of Exposure Outcomes on Life Course Circulating Corticosterone and Dehydroepiandrosterone (DHEA) Concentrations in Rats Exposed to Maternal Protein-Restricted Diets

K. Gerow, P. Nathanielsz, L. Reyes-Castro, 2023, Nutrients.

Transcutaneous scalp PO2 measurements in the fetal sheep: the influence of external pressure on the electrode or on the skin.

P. Nathanielsz, C. Jansen, 1983, American journal of obstetrics and gynecology.

Stimulation of the switch in myometrial activity from contractures to contractions in the pregnant sheep and nonhuman primate.

P. Nathanielsz, D. Giussani, W. Wu, 2010, Equine veterinary journal. Supplement.

DNA methylation networks underlying mammalian traits

Joseph A. Cook, S. Horvath, A. Lu, 2023, Science.

Universal DNA methylation age across mammalian tissues

R. Williams, J. Gaillard, D. Blumstein, 2023, Nature Aging.

Time-trend analysis of plasma C-21 steroids in fetal and maternal sheep during the last 18 days of gestation.

P. Nathanielsz, J. Buster, D. Magyar, 1980, Endocrinology.

Ultrastructural changes in the placenta of the ewe following foetal infusion of cortisol.

D. H. Steven, P. Nathanielsz, A. L. Thomas, 1975, Quarterly journal of experimental physiology and cognate medical sciences.

Effects of gestational age and labor on the expression of prostanoid receptor genes in pregnant baboon cervix.

P. Nathanielsz, G. C. Smith, W. Wu, 2001, Prostaglandins & other lipid mediators.

Ontogeny and programming of the fetal temporal cortical endocannabinoid system by moderate maternal nutrient reduction in baboons (Papio spp.)

P. Nathanielsz, S. Jenkins, N. Schlabritz-Loutsevitch, 2019, Physiological reports.

Cortical responsive neurostimulation in a baboon with genetic generalized epilepsy

A. Papanastassiou, P. Nathanielsz, R. Shade, 2021, Epilepsy & Behavior.

[An indwelling PO2 electrode used to monitor foetal vascular PO2 in the chronically catheterized foetal sheep [proceedings].

P. Nathanielsz, E. Krane, C. Jansen, 1977, The Journal of physiology.

A method for the quantitative assessment of uterine activity in the pregnant sheep [proceedings].

M. Carter, P. Nathanielsz, P. Steer, 1977, The Journal of physiology.

Baboon fetal arterial endothelial cells are more responsive to challenge by tumor necrosis factor α (TNF-α) than baboon fetal umbilical vein endothelial cells.

P. Nathanielsz, R. D. Wimmer, S. Jenkins, 2010, Atherosclerosis.

Maternal Obesity Programs the Premature Aging of Rat Offspring Liver Mitochondrial Electron Transport Chain Genes in a Sex-Dependent Manner

P. Nathanielsz, L. Reyes-Castro, E. Zambrano, 2023, Biology.

Assessment of label-free quantification and missing value imputation for proteomics in non-human primates

M. Olivier, Zeeshan Hamid, P. Nathanielsz, 2021, bioRxiv.

Maternal obesity programs reduced leptin signaling in the pituitary and altered GH/IGF1 axis function leading to increased adiposity in adult sheep offspring

P. Nathanielsz, S. Ford, J. F. Odhiambo, 2017, PloS one.

The effect of low doses of prostaglandin F2alpha infused into the aorta of unrestrained pregnant rats: observations on induction of parturition and effect on plasma progesterone concentration.

P. Nathanielsz, J. Buckle, 1973, Prostaglandins.

Impaired development of fetal serotonergic neurons in intrauterine growth restricted baboons

P. Nathanielsz, Brent J. Thompson, Cun Li, 2014, Journal of medical primatology.

Betamethasone-mediated vascular dysfunction and changes in hematological profile in the ovine fetus

L. Poston, P. Nathanielsz, M. Schwab, 1999 .

Effect of antenatal betamethasone treatment on microtubule‐associated proteins MAP1B and MAP2 in fetal sheep

P. Nathanielsz, M. Schwab, U. Sliwka, 2001, The Journal of physiology.

Up-regulation of oxytocin receptor messenger ribonucleic acid and protein by estradiol in the cervix of ovariectomized rat.

C. Umscheid, P. Nathanielsz, W. Wu, 1998, Biology of reproduction.

Relative contributions of maternal Western‐type high fat, high sugar diets and maternal obesity to altered metabolic function in pregnancy

P. Nathanielsz, E. Zambrano, 2017, The Journal of physiology.

Why primate models matter

J. Rogers, M. Nader, C. Shively, 2014, American journal of primatology.

Parathyroid hormone-related peptide (1 to 34) inhibits in vitro oxytocin-stimulated activity of pregnant baboon myometrium.

P. Nathanielsz, G. C. Smith, R. Wentworth, 1998, American journal of obstetrics and gynecology.

Daily and hourly temporal association between delta4-androstenedione-induced preterm myometrial contractions and maternal plasma estradiol and oxytocin concentrations in the 0.8 gestation rhesus monkey.

P. Nathanielsz, S. Jenkins, J. Winter, 1996, American journal of obstetrics and gynecology.

The effect of early to mid-gestational nutrient restriction on female offspring fertility and hypothalamic-pituitary-adrenal axis response to stress.

M. Nijland, P. Nathanielsz, S. Ford, 2010, Journal of animal science.

Sugared water consumption by adult offspring of mothers fed a protein-restricted diet during pregnancy results in increased offspring adiposity: the second hit effect

P. Nathanielsz, M. Martínez-Gómez, E. Zambrano, 2013, British Journal of Nutrition.

Maternal nutrient restriction predisposes ventricular remodeling in adult sheep offspring.

Jun Ren, P. Nathanielsz, S. Ford, 2013, The Journal of nutritional biochemistry.

Tissue-specific ontogenic expression of prostaglandin H synthase 2 in the ovine myometrium, endometrium, and placenta during late gestation and at spontaneous term labor.

P. Nathanielsz, X. Ma, W. Wu, 1999, American journal of obstetrics and gynecology.

The importance of altered gene promoter methylation and transcription factor binding in developmental programming of central appetitive drive

P. Nathanielsz, L. Cox, 2009, The Journal of physiology.

Up-regulation of Toll-like receptor 4/nuclear factor-kappaB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obese sheep at late gestation.

J. Tong, Xu Yan, Mei J. Zhu, 2010, Endocrinology.

Dynamics of cardiovascular responses to repeated partial umbilical cord compression in late-gestation sheep fetus.

P. Nathanielsz, J. Derks, N. Unno, 1997, American journal of physiology. Heart and circulatory physiology.

Cross-species withdrawal of MCL1 facilitates postpartum uterine involution in both the mouse and baboon.

P. Nathanielsz, P. Jeyasuria, E. Albrecht, 2013, Endocrinology.

Lung Fibrosis-associated Surfactant Protein A1 and C Variants Induce Latent Transforming Growth Factor β1 Secretion in Lung Epithelial Cells*

P. Nathanielsz, C. Garcia, W. Yuan, 2013, The Journal of Biological Chemistry.