D. Neumann

发表

Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2010, American journal of physiology. Renal physiology.

AMP-activated Kinase Inhibits the Epithelial Na+ Channel through Functional Regulation of the Ubiquitin Ligase Nedd4-2*

K. Hallows, D. Pearce, D. Neumann, 2006, Journal of Biological Chemistry.

Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

David Carling, Theo Wallimann, Uwe Schlattner, 2003 .

Phosphocreatine Interacts with Phospholipids, Affects Membrane Properties and Exerts Membrane-Protective Effects

B. Meier, R. Epand, R. Epand, 2012, PloS one.

The endocannabinoid system: Overview of an emerging multi-faceted therapeutic target.

D. Neumann, D. Chanda, J. Glatz, 2019, Prostaglandins, leukotrienes, and essential fatty acids.

Putative Role of Protein Palmitoylation in Cardiac Lipid-Induced Insulin Resistance

D. Neumann, J. Glatz, J. Luiken, 2020, International journal of molecular sciences.

Fluorescent labelling of membrane fatty acid transporter CD36 (SR-B2) in the extracellular loop

D. Neumann, J. Broers, R. Rodríguez-Calvo, 2019, PloS one.

In Vitro Methods to Study AMPK.

J. Voncken, D. Neumann, Xiaoqin Zhu, 2016, Experientia supplementum.

Epithelial Sodium Channel Inhibition by AMP-activated Protein Kinase in Oocytes and Polarized Renal Epithelial Cells*

John P. Johnson, K. Hallows, D. Neumann, 2005, Journal of Biological Chemistry.

Human embryonic stem cell-derived cardiomyocytes as an in vitro model to study cardiac insulin resistance.

R. Kamps, D. Neumann, D. Chanda, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli.

D. Carling, T. Wallimann, D. Neumann, 2003, Protein expression and purification.

Palmitate-Induced Vacuolar-Type H+-ATPase Inhibition Feeds Forward Into Insulin Resistance and Contractile Dysfunction

P. J. Simons, M. V. van Zandvoort, D. Neumann, 2017, Diabetes.

Cardiac contraction-induced GLUT4 translocation requires dual signaling input

D. Neumann, J. Glatz, J. Luiken, 2015, Trends in Endocrinology & Metabolism.

Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis*

D. Vertommen, D. Carling, T. Wallimann, 2003, Journal of Biological Chemistry.

Dual Mechanisms Regulating AMPK Kinase Action in the Ischemic Heart

L. Witters, T. Wallimann, D. Neumann, 2005, Circulation research.

2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes

D. Neumann, D. Chanda, W. Coumans, 2017, The Journal of Biological Chemistry.

The Phosphocreatine Circuit: Molecular and Cellular Physiology of Creatine Kinases, Sensitivity to Free Radicals, and Enhancement by Creatine Supplementation

T. Hornemann, R. Epand, R. Epand, 2007 .

Vacuolar H (cid:1) -ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase

Hui Li, K. Hallows, N. Pastor-Soler, 2010 .

Vacuolar H+-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase.

Hui Li, K. Hallows, N. Pastor-Soler, 2010, American journal of physiology. Renal physiology.

A molecular approach to the concerted action of kinases involved in energy homoeostasis.

T. Wallimann, D. Neumann, U. Schlattner, 2001, Biochemical Society transactions.

Tracking and quantification of 32P-labeled phosphopeptides in liquid chromatography matrix-assisted laser desorption/ionization mass spectrometry.

Ramon F. Thali, T. Wallimann, R. Scholz, 2009, Analytical biochemistry.

2 Tracking and quantification of 32 P-labeled phosphopeptides in liquid 3 chromatography matrix-assisted laser desorption/ionization mass spectrometry

Ramon F. Thali, T. Wallimann, R. Scholz, 2009 .

Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR–v-ATPase axis

M. Zeegers, D. Neumann, F. V. van Nieuwenhoven, 2021, Molecular metabolism.

Molecular mechanism of lipid-induced cardiac insulin resistance and contractile dysfunction.

D. Neumann, J. Glatz, J. Luiken, 2016, Prostaglandins, leukotrienes, and essential fatty acids.

Structural Properties of AMP-activated Protein Kinase

A. Rufer, D. Svergun, S. Müller, 2008, Journal of Biological Chemistry.

Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake.

D. Neumann, D. Chanda, J. Glatz, 2016, Biochimica et biophysica acta.

Assessment of AMPK-Stimulated Cellular Long-Chain Fatty Acid and Glucose Uptake.

D. Neumann, D. Chanda, W. Coumans, 2018, Methods in molecular biology.

Phosphatidylinositol 4-kinase IIIβ mediates contraction-induced GLUT4 translocation and shows its anti-diabetic action in cardiomyocytes

D. Neumann, J. Glatz, J. Luiken, 2020, Cellular and Molecular Life Sciences.

Calcium signaling recruits substrate transporters GLUT4 and CD36 to the sarcolemma without increasing cardiac substrate uptake.

M. V. van Zandvoort, R. Schwenk, D. Neumann, 2014, American journal of physiology. Endocrinology and metabolism.

Dual Mechanisms Regulating AMP-Activated Protein Kinase Action in the Ischemic Heart

L. Witters, D. Neumann, E. Miller, 2005 .

Activation of the metabolic sensor AMP-activated protein kinase inhibits aquaporin-2 function in kidney principal cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2016, American journal of physiology. Renal physiology.

Pharmacological Targeting of AMP-Activated Protein Kinase and Opportunities for Computer-Aided Drug Design.

G. Nicolaes, D. Neumann, M. Miglianico, 2016, Journal of medicinal chemistry.

MSP is a negative regulator of inflammation and lipogenesis in ex vivo models of non-alcoholic steatohepatitis

D. Neumann, D. Chanda, R. Shiri-Sverdlov, 2016, Experimental & Molecular Medicine.

The PP1‐R6 protein phosphatase holoenzyme is involved in the glucose‐induced dephosphorylation and inactivation of AMP‐activated protein kinase, a key regulator of insulin secretion, in MIN6 β cells

M. Bollen, D. Neumann, M. Beullens, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The PP 1R 6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase , a key regulator of insulin secretion , in MIN 6 cells

M. Bollen, D. Neumann, M. Beullens, 2010 .

PKA Regulates Vacuolar H+-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells*

Hui Li, K. Hallows, N. Pastor-Soler, 2010, The Journal of Biological Chemistry.

AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.

Hui Li, K. Hallows, N. Pastor-Soler, 2009, American journal of physiology. Cell physiology.

Endosomal v-ATPase as a Sensor Determining Myocardial Substrate Preference

D. Neumann, J. Glatz, J. Luiken, 2022, Metabolites.

Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes

D. Neumann, M. Rider, S. Horman, 2009, FEBS letters.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model

D. Neumann, D. Chanda, P. J. V. van Gorp, 2016, PloS one.

Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance.

D. Neumann, J. Glatz, J. Luiken, 2020, Biochimica et biophysica acta. Molecular basis of disease.

The interaction between AMPKβ2 and the PP1-targeting subunit R6 is dynamically regulated by intracellular glycogen content.

J. Voncken, D. Neumann, D. Chanda, 2016, The Biochemical journal.

WITHDRAWN: The Endocannabinoid System: Overview of an Emerging Multi-faceted Therapeutic Target

D. Neumann, D. Chanda, J. Glatz, 2018, Prostaglandins, Leukotrienes and Essential Fatty Acids.

AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney.

Hui Li, K. Hallows, N. Pastor-Soler, 2013, American journal of physiology. Renal physiology.

AMP-activated protein kinase undergoes nucleotide-dependent conformational changes

Zhi-Xin Wang, L. Chen, Jia-wei Wu, 2012, Nature Structural &Molecular Biology.

MSP: an emerging player in metabolic syndrome.

D. Neumann, D. Chanda, R. Shiri-Sverdlov, 2015, Cytokine & growth factor reviews.

GSK-3 Inhibitors: Anti-Diabetic Treatment Associated with Cardiac Risk?

D. Neumann, M. Nabben, 2016, Cardiovascular Drugs and Therapy.

Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance.

R. Schwenk, D. Neumann, B. Janssen, 2014, Journal of molecular and cellular cardiology.

AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding.

Jong-Tae Park, D. Neumann, D. Stapleton, 2012, Biophysical journal.

AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase*♦

B. Viollet, D. Vertommen, D. Neumann, 2008, Journal of Biological Chemistry.

Conserved regulatory elements in AMPK

Zhi-Xin Wang, P. Li, D. Neumann, 2013, Nature.

Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491*

D. Vertommen, R. Heath, D. Carling, 2006, Journal of Biological Chemistry.

AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits

B. Viollet, A. Deshmukh, J. Zierath, 2006, Diabetes.

Activation of the AMP-activated Protein Kinase by the Anti-diabetic Drug Metformin in Vivo

W. G. Wiles, J. Nelson, M. Freeman, 2004, Journal of Biological Chemistry.

Is TAK1 a Direct Upstream Kinase of AMPK?

D. Neumann, 2018, International journal of molecular sciences.

Homo-oligomerization and Activation of AMP-activated Protein Kinase Are Mediated by the Kinase Domain αG-Helix*

B. Viollet, P. Konarev, C. Polge, 2009, The Journal of Biological Chemistry.

Co-expression of LKB1, MO25α and STRADα in bacteria yield the functional and active heterotrimeric complex

T. Wallimann, D. Neumann, M. Suter, 2007 .

Activation of Protein Kinase Cζ by Peroxynitrite Regulates LKB1-dependent AMP-activated Protein Kinase in Cultured Endothelial Cells*

Miao Zhang, M. Zou, D. Neumann, 2006, Journal of Biological Chemistry.

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

S. Geley, D. Neumann, D. Chanda, 2020, Nature Communications.

Identification of the Serine 307 of LKB1 as a Novel Phosphorylation Site Essential for Its Nucleocytoplasmic Transport and Endothelial Cell Angiogenesis

M. Zou, R. Scholz, D. Neumann, 2009, Molecular and Cellular Biology.

AMPK β subunits display isoform specific affinities for carbohydrates

S. Ralph, M. Bailey, Jong-Tae Park, 2010, FEBS letters.

Dissecting the Role of 5′-AMP for Allosteric Stimulation, Activation, and Deactivation of AMP-activated Protein Kinase*

Uwe Riek, Theo Wallimann, Uwe Schlattner, 2006, Journal of Biological Chemistry.

MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points

J. Voncken, E. Speel, B. Wouters, 2015, PloS one.

PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

B. Viollet, T. Mäkelä, Kari Vaahtomeri, 2010, The EMBO journal.

Phosphorylation of LKB1 at Serine 428 by Protein Kinase C-&zgr; Is Required for Metformin-Enhanced Activation of the AMP-Activated Protein Kinase in Endothelial Cells

M. Zou, R. Scholz, D. Neumann, 2008, Circulation.

Dietary Phytoestrogens Activate AMP-Activated Protein Kinase With Improvement in Lipid and Glucose Metabolism

M. Vinciguerra, P. Meda, M. Foti, 2008, Diabetes.

New candidate targets of AMP-activated protein kinase in murine brain revealed by a novel multidimensional substrate-screen for protein kinases.

Ramon F. Thali, T. Wallimann, D. Neumann, 2007, Journal of proteome research.

beta1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells

Hui Li, K. Hallows, D. Neumann, 2019 .

β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells

Hui Li, K. Hallows, D. Neumann, 2018, The Journal of Biological Chemistry.

Ketone Body Exposure of Cardiomyocytes Impairs Insulin Sensitivity and Contractile Function through Vacuolar-Type H+-ATPase Disassembly—Rescue by Specific Amino Acid Supplementation

D. Neumann, B. Westenbrink, J. Glatz, 2022, International journal of molecular sciences.

Novel candidate substrates of AMP-activated protein kinase identified in red blood cell lysates.

Ramon F. Thali, R. Scholz, D. Neumann, 2010, Biochemical and biophysical research communications.

The Recruitment of AMP-activated Protein Kinase to Glycogen Is Regulated by Autophosphorylation

Ramon F. Thali, R. Scholz, D. Neumann, 2015, The Journal of Biological Chemistry.

Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process*

Ramon F. Thali, R. Scholz, D. Neumann, 2010, The Journal of Biological Chemistry.

AMPK activation by long chain fatty acyl analogs.

B. Kalderon, J. Bar-Tana, D. Neumann, 2008, Biochemical pharmacology.

AMP-Activated Protein Kinase Signalling

B. Viollet, D. Neumann, 2019, International journal of molecular sciences.

Glucose‐dependent regulation of AMP‐activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway

M. Bollen, D. Neumann, M. Beullens, 2012, FEBS letters.

C-terminal Lysines Determine Phospholipid Interaction of Sarcomeric Mitochondrial Creatine Kinase*

Theo Wallimann, Uwe Schlattner, Florian Gehring, 2004, Journal of Biological Chemistry.

AMP-activated Protein Kinase Up-regulates Mitogen-activated Protein (MAP) Kinase-interacting Serine/Threonine Kinase 1a-dependent Phosphorylation of Eukaryotic Translation Initiation Factor 4E*

B. Viollet, J. Voncken, Ramon F. Thali, 2016, The Journal of Biological Chemistry.

Cross-talk between Two Essential Nutrient-sensitive Enzymes

J. Shabanowitz, D. Hunt, G. Hart, 2014, The Journal of Biological Chemistry.

Withdrawal: Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo : Role of mitochondrial reactive nitrogen species.

J. Nelson, M. Freeman, M. Zou, 2019, The Journal of Biological Chemistry.

Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-activated Protein Kinase*

A. Mehta, K. Hallows, J. King, 2012, The Journal of Biological Chemistry.

AICAR Protects against High Palmitate/High Insulin-Induced Intramyocellular Lipid Accumulation and Insulin Resistance in HL-1 Cardiac Cells by Inducing PPAR-Target Gene Expression

D. Neumann, L. Masana, M. Vázquez-Carrera, 2015, PPAR research.

Augmenting Vacuolar H+-ATPase Function Prevents Cardiomyocytes from Lipid-Overload Induced Dysfunction

D. Neumann, J. Glatz, J. Luiken, 2020, International journal of molecular sciences.

Regulation of brain-type creatine kinase by AMP-activated protein kinase: interaction, phosphorylation and ER localization.

Ramon F. Thali, D. Neumann, U. Schlattner, 2014, Biochimica et biophysica acta.

Letter by Neumann et al regarding article, "Myostatin regulates energy homeostasis in the heart and prevents heart failure".

D. Neumann, J. Glatz, J. Luiken, 2015, Circulation research.

The CCNY (cyclin Y)-CDK16 kinase complex: a new regulator of autophagy downstream of AMPK

D. Neumann, B. Lüscher, J. Vervoorts, 2020, Autophagy.

Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.

D. Neumann, D. Chanda, E. Barroso, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Signaling by AMP‐activated Protein Kinase

D. Hardie, T. Wallimann, D. Neumann, 2007 .

Is TAK1 a Direct Upstream Kinase of AMPK?

D. Neumann, 2018, International journal of molecular sciences.

Novel factors and mechanisms in control of CD36-mediated cardiac fatty acid transport

Y. Angin, D. Neumann, E. Blaak, 2013 .

Nutrient-sensitive Enzymes : O-GlcNAc Cross-talk between Two Essential Glycobiology and Extracellular Matrices :

J. Shabanowitz, D. Hunt, G. Hart, 2014 .

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

S. Geley, D. Neumann, D. Chanda, 2020, Nature Communications.

PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

B. Viollet, T. Mäkelä, Kari Vaahtomeri, 2010, The EMBO journal.

Glucose‐dependent regulation of AMP‐activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway

M. Bollen, D. Neumann, M. Beullens, 2012, FEBS letters.

Co-expression of LKB1, MO25alpha and STRADalpha in bacteria yield the functional and active heterotrimeric complex.

T. Wallimann, D. Neumann, M. Suter, 2007, Molecular biotechnology.

Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

M. Carlson, D. Carling, T. Wallimann, 2003 .

Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis

D. Neumann, J. Luiken, M. Nabben, 2024, Circulation research.

Homo-oligomerization and Activation of AMP-activated Protein Kinase Are Mediated by the Kinase

Ramon F. Thali, D. Neumann, U. Schlattner, 2009 .

The endocannabinoid system: Overview of an emerging multi-faceted therapeutic target.

D. Neumann, J. Glatz, Dipanjan Chandaa, 2019, Prostaglandins, Leukotrienes and Essential Fatty Acids.

Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes.

D. Neumann, M. Vázquez-Carrera, M. Tajes, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.