Gi-Wook Hwang

发表

siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells.

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2010, The Journal of toxicological sciences.

Immature Core protein of hepatitis C virus induces an unfolded protein response through inhibition of ERAD‐L in a yeast model system

S. Kuge, A. Naganuma, M. Kohara, 2017, Genes to cells : devoted to molecular & cellular mechanisms.

Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2010, The Journal of toxicological sciences.

Effects of long-term cadmium exposure on urinary metabolite profiles in mice.

Gi-Wook Hwang, S. Sarma, A. Saleem, 2018, The Journal of toxicological sciences.

Combined effect of circadian dysfunction and cadmium on immune suppression

N. Miura, Gi-Wook Hwang, M. Ikeda, 2016 .

Identification of substrates of F‐box protein involved in methylmercury toxicity in yeast cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2015, FEBS letters.

Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2011, The Journal of toxicological sciences.

Identification of F‐box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae

A. Naganuma, Gi-Wook Hwang, Yosuke Ishida, 2006, FEBS letters.

Deletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradation.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2013, The Journal of toxicological sciences.

Adverse health effects of humidifier disinfectants in Korea: lung toxicity of polyhexamethylene guanidine phosphate.

A. Naganuma, Gi-Wook Hwang, K. Chung, 2016, The Journal of toxicological sciences.

Comprehensive analyses of the cysteine thiol oxidation of PKM2 reveals the effects of multiple oxidation on cellular oxidative stress response

S. Kuge, Gi-Wook Hwang, T. Toyama, 2020, bioRxiv.

Elaidic Acid Potentiates Extracellular ATP-Induced Apoptosis via the P2X7-ROS-ASK1-p38 Axis in Microglial Cell Lines.

K. Fukunaga, Gi-Wook Hwang, A. Matsuzawa, 2020, Biological & pharmaceutical bulletin.

Hepatitis C virus inhibitor synergism suggests multistep interactions between heat-shock protein 90 and hepatitis C virus replication.

S. Kuge, A. Naganuma, M. Kohara, 2016, World journal of hepatology.

Evaluation of M1-microglial activation by neurotoxic metals using optimized organotypic cerebral slice cultures.

A. Naganuma, S. Koizumi, Gi-Wook Hwang, 2019, The Journal of toxicological sciences.

Ubiquitin‐proteasome system is responsible for the protection of yeast and human cells against methylmercury

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Methylmercury causes neuronal cell death via M1-microglial activation in organotypic slices prepared from mouse cerebral cortex

A. Naganuma, Gi-Wook Hwang, T. Toyama, 2019, Fundamental Toxicological Sciences.

Induction of chemokine CCL3 by NF-κB reduces methylmercury toxicity in C17.2 mouse neural stem cells.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2019, Environmental toxicology and pharmacology.

Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2011, The Journal of toxicological sciences.

Transport of pyruvate into mitochondria is involved in methylmercury toxicity

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2016, Scientific Reports.

Overexpression of RPN8, SKP1, MIA40 or MES1 increases resistance to cadmium in Saccharomyces cerevisiae

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2014 .

Role of the Ubiquitin-proteasome System in Methylmercury Toxicity in Saccharomyces cerevisiae

Gi-Wook Hwang, 2011 .

Methylmercury Induces Cytotoxicity through Inhibition of PTEN Activity by a Decrease in Its Solubility

N. Miura, S. Kuge, A. Naganuma, 2018 .

Lethal chronotoxicity induced by seven metal compounds in mice.

N. Miura, M. Suzui, Gi-Wook Hwang, 2018, The Journal of toxicological sciences.

Role of intracellular defense factors against methylmercury toxicity.

Gi-Wook Hwang, 2012, Biological & pharmaceutical bulletin.

Akr1 attenuates methylmercury toxicity through the palmitoylation of Meh1 as a subunit of the yeast EGO complex.

N. Miura, S. Kuge, A. Naganuma, 2017, Biochimica et biophysica acta. General subjects.

Activation of ornithine decarboxylase protects against methylmercury toxicity by increasing putrescine

N. Miura, A. Naganuma, Gi-Wook Hwang, 2018, Toxicology and applied pharmacology.

Effect of Metallothionein-III on Mercury-Induced Chemokine Gene Expression

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2018, Toxics.

Putrescine selectively alleviates methylmercury toxicity in C17.2 mouse neural stem cells

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2018 .

Methylmercury induces the expression of TNF-α selectively in the brain of mice

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2016, Scientific Reports.

Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains

N. Miura, A. Naganuma, Gi-Wook Hwang, 2015 .

Hydrogen Peroxide Causes Cell Death via Increased Transcription of HOXB13 in Human Lung Epithelial A549 Cells

A. Naganuma, Yoshiro Saito, Gi-Wook Hwang, 2020, Toxics.

A screening method for growth-dependent genes involved in the cytotoxicity of chemicals in Saccharomyces cerevisiae

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2014 .

siRNA-mediated silencing of the gene for heat shock transcription factor 1 causes hypersensitivity to methylmercury in HEK293 cells.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2011, The Journal of toxicological sciences.

Deubiquitinase USP54 attenuates methylmercury toxicity in human embryonic kidney 293 cells

A. Naganuma, Gi-Wook Hwang, A. Matsuzawa, 2022, Fundamental Toxicological Sciences.

Increased expression of TCF3, transcription factor 3, is a defense response against methylmercury toxicity in mouse neuronal C17.2 cells

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2021, Toxicological Research.

Methylmercury toxic mechanism related to protein degradation and chemokine transcription

A. Naganuma, Gi-Wook Hwang, M. Satoh, 2020, Environmental Health and Preventive Medicine.

Increased putrescine levels due to ODC1 overexpression prevents mitochondrial dysfunction-related apoptosis induced by methylmercury.

N. Miura, A. Naganuma, Gi-Wook Hwang, 2020, Life Science.

Chemokine CCL4 Induced in Mouse Brain Has a Protective Role against Methylmercury Toxicity

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2018, Toxics.

Small interfering RNA-mediated knockdown of the transcription factor TCF3 enhances sensitivity to methylmercury in mouse neural stem cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2017 .

Small interfering RNA-mediated knockdown of the transcription factor TCF 3 enhances sensitivity to methylmercury in mouse neural stem cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2017 .

Citrulline enhances methylmercury toxicity in HEK293 and C17.2 cells

A. Naganuma, Gi-Wook Hwang, T. Toyama, 2015 .

Metabolomic analysis of low molecular weight substances released into medium from HEK293 cells treated with methylmercury

A. Naganuma, Gi-Wook Hwang, T. Toyama, 2015 .

Methylmercury induces release of a cytotoxic factor from HEK293 cells into medium

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2015 .

Identification of transcription factors activated by methylmercury in mouse brain

N. Miura, A. Naganuma, Gi-Wook Hwang, 2017 .

Effect of heat shock protein gene expression on cadmium toxicity in human proximal tubular cells

Gi-Wook Hwang, M. Satoh, Jin‐Yong Lee, 2018, Fundamental Toxicological Sciences.

Effect of chronic cadmium exposure on the gene expression of Birc family in the mouse kidney and liver

Gi-Wook Hwang, M. Satoh, Jin‐Yong Lee, 2017 .

Overexpression of palmitoyl transferase HIP14 confers resistance to methylmercury in SH-SY5Y human neuroblastoma cells

N. Miura, S. Kuge, A. Naganuma, 2016 .

Urinary proteome profile of renal papillary necrosis in experimental model rats

A. Naganuma, A. Unami, Gi-Wook Hwang, 2017 .

A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2011, The Journal of toxicological sciences.

FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation.

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2014, The Journal of toxicological sciences.

BPB Reports

Gi-Wook Hwang, Jin‐Yong Lee, 2020 .

Effect of GATA Transcription Factors on Cadmium Toxicity in Human Proximal Tubular Cells

Gi-Wook Hwang, M. Satoh, Jin‐Yong Lee, 2019, BPB Reports.

Overexpression of CLN1, CLN2, or ERG13 increases resistance to adriamycin in Saccharomyces cerevisiae.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2011, The Journal of toxicological sciences.

The Journal of Toxicological Sciences

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2004 .

Fundamental Toxicological Sciences

A. Naganuma, Gi-Wook Hwang, T. Kumagai, 2020 .

Characterization of Surface Properties, Osteoblast Cell Culture in Vitro and Processing with Flow-Viscosity of Ni-Free Ti-Based Bulk Metallic Glass for Biomaterials

A. Inoue, Gi-Wook Hwang, J. Oak, 2009 .

Identification of ARNT-regulated BIRC3 as the target factor in cadmium renal toxicity

Moo-Yeol Lee, Gi-Wook Hwang, M. Satoh, 2017, Scientific Reports.

Methylmercury induces the expression of chemokine CCL4 via SRF activation in C17.2 mouse neural stem cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2019, Scientific Reports.

Chronotoxicity of Streptomycin-Induced Renal Injury in Mice.

N. Miura, Gi-Wook Hwang, Tohru Maeda, 2020, Biological & pharmaceutical bulletin.

Chronotoxicity of bromobenzene-induced hepatic injury in mice.

N. Miura, Gi-Wook Hwang, K. Ohtani, 2017, The Journal of toxicological sciences.

Multidirectional analyses of hepatic chronotoxicity induced by cadmium in mice.

N. Miura, Gi-Wook Hwang, M. Ikeda, 2017, The Journal of toxicological sciences.

Gefitinib initiates sterile inflammation by promoting IL-1β and HMGB1 release via two distinct mechanisms

Gi-Wook Hwang, A. Matsuzawa, T. Noguchi, 2021, Cell death & disease.

Methylmercury induces CCL2 expression through activation of NF-κB in human 1321N1 astrocytes.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2012, The Journal of toxicological sciences.

Methylmercury induces CCL 2 expression through activation of NF-κB in human 1321 N 1 astrocytes

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2012 .

The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages

Gi-Wook Hwang, A. Matsuzawa, T. Noguchi, 2021, The Journal of Antibiotics.

Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae.

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2002, Molecular pharmacology.

Overexpression of Rad23 Confers Resistance to Methylmercury in Saccharomyces cerevisiae via Inhibition of the Degradation of Ubiquitinated Proteins

A. Naganuma, Gi-Wook Hwang, D. Sasaki, 2005, Molecular Pharmacology.

The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2016, PloS one.

The protein transportation pathway from Golgi to vacuoles via endosomes plays a role in enhancement of methylmercury toxicity

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2014, Scientific Reports.

Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2.

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2005, Biochemical and biophysical research communications.

Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos

Gi-Wook Hwang, J. Aoki, A. Matsuzawa, 2018, Cell Death & Disease.

Investigation of intracellular factors involved in methylmercury toxicity.

T. Furuchi, N. Miura, S. Kuge, 2002, The Tohoku journal of experimental medicine.

The polypeptide antibiotic polymyxin B acts as a pro-inflammatory irritant by preferentially targeting macrophages

Gi-Wook Hwang, A. Matsuzawa, T. Noguchi, 2021, The Journal of Antibiotics.

Identification of growth-dependent genes involved in paraquat toxicity in Saccharomyces cerevisiae

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2014 .

The Antibiotic Cefotaxime Works as Both an Activator of Nrf2 and an Inducer of HSP70 in Mammalian Cells

Gi-Wook Hwang, A. Matsuzawa, T. Noguchi, 2020, BPB reports.

Methylmercury induces a brain-specific increase in chemokine CCL4 expression in mice.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2012, The Journal of toxicological sciences.

Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

A. Naganuma, Yoshiro Saito, Gi-Wook Hwang, 2021, Scientific Reports.

Global chemokine expression in methylmercury-treated mice: methylmercury induces brain-specific expression of CCL3 and CCL4.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2013, The Journal of toxicological sciences.

The Nuclear Protein HOXB13 Enhances Methylmercury Toxicity by Inducing Oncostatin M and Promoting Its Binding to TNFR3 in Cultured Cells

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2019, Cells.

siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2010, The Journal of toxicological sciences.

Blood vessel remodeling in the cerebral cortex induced by binge alcohol intake in mice

Gi-Wook Hwang, M. Kondo, K. Nakayama, 2022, Toxicological Research.

High sensitivity of testicular function to titanium nanoparticles.

N. Miura, Gi-Wook Hwang, K. Ohtani, 2017, The Journal of toxicological sciences.

Biphasic adverse effect of titanium nanoparticles on testicular function in mice

N. Miura, Gi-Wook Hwang, K. Ohtani, 2019, Scientific Reports.

Impairment of fertilization efficiency in mice following nano-sized titanium exposure

N. Miura, Gi-Wook Hwang, K. Ohtani, 2019, Fundamental Toxicological Sciences.

Perinatal Exposure to Arsenic in Drinking Water Alters Glutamatergic Neurotransmission in the Striatum of C57BL/6 Mice

Kisok Kim, Gi-Wook Hwang, Kyunghwa Sung, 2018, Biological Trace Element Research.

Silencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cells.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2010, The Journal of toxicological sciences.

Sensitivity of MT-III null mice upon chronic exposure to cadmium

Moo-Yeol Lee, Gi-Wook Hwang, M. Satoh, 2016 .

Knockdown of Acyl-CoA thioesterase 9 gene expression by siRNA confers resistance to arsenite in HEK293 cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2015 .

Brain-specific induction of secretoglobin 3A1 expression in mice treated with methylmercury.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2013, The Journal of toxicological sciences.

Brain-specific expression of chemokines by methylmercury in mice

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2012 .

Overexpression of the novel F-box protein Ymr258c confers resistance to methylmercury in Saccharomyces cerevisiae.

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2009, The Journal of toxicological sciences.

Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2009, The Journal of toxicological sciences.

The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2008, Life sciences.

Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4.

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2007, Biochemical and biophysical research communications.

Whi2 enhances methylmercury toxicity in yeast via inhibition of Akr1 palmitoyltransferase activity.

N. Miura, S. Kuge, A. Naganuma, 2016, Biochimica et biophysica acta.

Ubiquitin-proteasome system as a factor that determine the sensitivity to methylmercury.

Gi-Wook Hwang, 2007, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos

Gi-Wook Hwang, J. Aoki, A. Matsuzawa, 2018, Cell Death & Disease.

Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth

A. Naganuma, Gi-Wook Hwang, A. Matsuzawa, 2023, Archives of Toxicology.

Methylmercury induces the expression of chemokine CCL4 via SRF activation in C17.2 mouse neural stem cells

S. Kuge, A. Naganuma, Gi-Wook Hwang, 2019, Scientific Reports.

BPB Reports

Gi-Wook Hwang, A. Matsuzawa, T. Noguchi, 2020 .

The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.

T. Furuchi, A. Naganuma, Gi-Wook Hwang, 2008, Life sciences.

Perinatal Exposure to Arsenic in Drinking Water Alters Glutamatergic Neurotransmission in the Striatum of C57BL/6 Mice

Kisok Kim, Gi-Wook Hwang, Kyunghwa Sung, 2018, Biological Trace Element Research.

Ubiquitin-conjugating enzyme Cdc34 mediates methylmercury resistance in Saccharomyces cerevisiae by increasing Whi2 degradation.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2012, The Journal of toxicological sciences.

Changes in the levels of low molecular weight metabolites in the mouse cerebellum following treatment with methylmercury.

A. Naganuma, Gi-Wook Hwang, Tsutomu Takahashi, 2013, The Journal of toxicological sciences.