A. Woods

发表

Activation of AMP-activated Protein Kinase by Vascular Endothelial Growth Factor Mediates Endothelial Angiogenesis Independently of Nitric-oxide Synthase*

B. Viollet, D. Carling, Nadine Stahmann, 2010, The Journal of Biological Chemistry.

Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

David Carling, Theo Wallimann, Uwe Schlattner, 2003 .

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

David Carling, Seung-Pyo Hong, M. Carlson, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo.

J. Scott, M. Carlson, Xiaolu Yang, 1994, The Journal of biological chemistry.

Chronic Activation of γ 2 AMPK Induces Obesity and Reduces Beta Cell Function

Robin J. W. Willows, Jonathan, Parvathy E. Harikumar, 2016 .

To the Editor

D. Carling, A. Woods, J. Leiper, 2012, Nature Genetics.

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli.

D. Carling, T. Wallimann, D. Neumann, 2003, Protein expression and purification.

Explorer LKB 1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis

Fiona C. Denison, Lee B. Smith, P. Muckett, 2017 .

LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis

Fiona C. Denison, Lee B. Smith, P. Muckett, 2011, PloS one.

Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis*

D. Vertommen, D. Carling, T. Wallimann, 2003, Journal of Biological Chemistry.

Characterization of an Alternative Splice Variant of LKB1*

Fiona C. Denison, D. Carling, A. Woods, 2009, Journal of Biological Chemistry.

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

M. Duchen, A. Bornot, Maryam Clausen, 2019, Nature Metabolism.

Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice

Mark A. Smith, D. Carling, D. Withers, 2015, Cell reports.

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495.

D. Carling, A. Woods, K. Spengler, 2020, The Biochemical journal.

Characterization of AMP-activated Protein Kinase and Subunits

D. Carling, A. Woods, F. Smith, 1996, The Journal of Biological Chemistry.

The α1 and α2 isoforms of the AMP‐activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro

D. Hardie, D. Carling, A. Woods, 1996 .

The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro.

J. Scott, D. Carling, A. Woods, 1996, FEBS letters.

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

P. Muckett, M. Bohlooly-y, D. Carling, 2017, Cell reports.

Thrombin Activates AMP-Activated Protein Kinase in Endothelial Cells via a Pathway Involving Ca 2 (cid:1) /Calmodulin-Dependent Protein Kinase Kinase (cid:2)

D. Carling, Nadine Stahmann, A. Woods, 2006 .

The Nuclear Receptor Cofactor RIP140 is Required for the Regulation of Hepatic Lipid and Glucose Metabolism by LXR

A. Woods, A. Seth, B. Herzog, 2007 .

University of Birmingham Mammalian 2 AMPK regulates intrinsic heart rate

D. Paterson, O. Wolkenhauer, E. Lakatta, 2017 .

Bypassing the glucose/fatty acid cycle: AMP-activated protein kinase.

D. Carling, A. Woods, L. Fryer, 2003, Biochemical Society transactions.

AMP-activated protein kinase : greater AMP dependence , and preferential nuclear localization , of complexes containing the α 2 isoform

A. Prescott, D. Hardie, S. Hawley, 1998 .

Chronic Activation of g 2 AMPK Induces Obesity and Reduces b Cell Function

Robin J. W. Willows, Parvathy E. Harikumar, Nathan R. Qi, 2016 .

The regulation of AMP-activated protein kinase by phosphorylation.

D. Carling, A. Woods, M. Davison, 2000, The Biochemical journal.

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells.

S. Baldwin, D. Carling, A. Woods, 2002, The Biochemical journal.

Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro.

J. Scott, D. Carling, A. Woods, 1996, The Journal of biological chemistry.

Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

R. Heath, M. Carlson, D. Carling, 2005, Cell metabolism.

Thrombin Activates AMP-Activated Protein Kinase in Endothelial Cells via a Pathway Involving Ca2+/Calmodulin-Dependent Protein Kinase Kinase β

D. Carling, Nadine Stahmann, A. Woods, 2006, Molecular and Cellular Biology.

Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491*

D. Vertommen, R. Heath, D. Carling, 2006, Journal of Biological Chemistry.

Thrombin Activates AMP-Activated Protein Kinase in Endothelial Cells via a Pathway Involving Ca 2 /Calmodulin-Dependent

D. Carling, Nadine Stahmann, A. Woods, 2006 .

CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis.

A. Nikitin, Alice E. Pollard, Lucy Penfold, 2018, Cancer research.

Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase*

S. Hawley, D. Carling, A. Woods, 1996, The Journal of Biological Chemistry.

AMP-activated protein kinase: new regulation, new roles?

C. Thornton, D. Carling, A. Woods, 2012, The Biochemical journal.

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Janet M. Thornton, David Carling, Linda Partridge, 2009, Science.

Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

D. Carling, M. Foretz, D. Azzout-Marniche, 2000, Molecular and Cellular Biology.

AMP-activated Protein Kinase Plays a Role in the Control of Food Intake*

D. Carling, A. Woods, S. Bloom, 2004, Journal of Biological Chemistry.

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice

A. Ashworth, R. Goldin, P. Muckett, 2010, The Biochemical journal.

Mammalian γ2 AMPK regulates intrinsic heart rate

D. Paterson, O. Wolkenhauer, E. Lakatta, 2017, Nature Communications.

The AMP‐Activated Protein Kinase Is Involved in the Regulation of Ketone Body Production by Astrocytes

M. L. de Ceballos, D. Carling, A. Woods, 1999, Journal of neurochemistry.

Purification of the AMP-activated protein kinase on ATP-gamma-sepharose and analysis of its subunit structure.

T. Haystead, S. Hawley, D. Carling, 1994, European journal of biochemistry.

Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

Julian J. Emmanuel, A. Ashworth, Mark A. Smith, 2011, Diabetes.

The regulation of AMP-activated protein kinase by upstream kinases

D. Carling, A. Woods, M. Sanders, 2008, International Journal of Obesity.

The AMP‐activated Protein Kinase Gene is Highly Expressed in Rat Skeletal Muscle

D. Hardie, S. Hawley, D. Carling, 1995 .

The AMP-activated protein kinase gene is highly expressed in rat skeletal muscle. Alternative splicing and tissue distribution of the mRNA.

J. Scott, S. Hawley, D. Carling, 1995, European journal of biochemistry.

Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity

H. Watkins, B. Beutler, D. Carling, 2016, Proceedings of the National Academy of Sciences.

Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism.

J. Scott, K. Aguan, C. Sidebottom, 1994, The Journal of biological chemistry.

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

Ming‐Fei Hsu, B. Viollet, D. Vertommen, 2016, Nature Communications.

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Robin J. W. Willows, Parvathy E. Harikumar, Nathan R. Qi, 2016, Cell Metabolism.

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Robin J. W. Willows, Parvathy E. Harikumar, Nathan R. Qi, 2016, Cell Metabolism.

AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform.

A. Prescott, S. Hawley, D. Carling, 1998, The Biochemical journal.

The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor.

A. Woods, M. Parker, Roger White, 2007, Molecular endocrinology.

Molecular characterization of the AMP-activated protein kinase and its role in cellular metabolism.

C. Thornton, D. Carling, A. Woods, 1997, Biochemical Society transactions.

AMPK activation protects against prostate cancer by inducing a catabolic cellular state.

D. Leach, A. Nikitin, Alice E. Pollard, 2023, Cell reports.

The role of ATM in response to metformin treatment and activation of AMPK.

D. Carling, A. Woods, J. Leiper, 2012, Nature genetics.

Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies.

K. Gull, A. Woods, A. Woods, 1989, Journal of cell science.

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Robin J. W. Willows, Parvathy E. Harikumar, Nathan R. Qi, 2016, Cell metabolism.

AMPK activation protects against diet induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose 2

M. Duchen, Maryam Clausen, A. Sardini, 2018 .

Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade

M. Carlson, D. Carling, T. Wallimann, 2003 .