G. Sweeney

发表

Regulation of fatty acid uptake and metabolism in L6 skeletal muscle cells by resistin

R. Palanivel, G. Sweeney, 2005, FEBS letters.

Stimulation of glucose and amino acid transport and activation of the insulin signaling pathways by insulin lispro in L6 skeletal muscle cells.

R. Somwar, A. Klip, G. Sweeney, 1998, Clinical therapeutics.

Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers

J. Grigull, J. Zhao, G. Sweeney, 2017, Scientific Reports.

Adiponectin is expressed by skeletal muscle fibers and influences muscle phenotype and function.

Y. Liu, A. Xu, G. Sweeney, 2008, American journal of physiology. Cell physiology.

Hyperglycemia- and hyperinsulinemia-induced alteration of adiponectin receptor expression and adiponectin effects in L6 myoblasts.

R. Palanivel, G. Sweeney, Y. Liu, 2005, Journal of molecular endocrinology.

Adiponectin increases LPL activity via RhoA/ROCK-mediated actin remodelling in adult rat cardiomyocytes.

F. Thong, B. Rodrigues, G. Sweeney, 2011, Endocrinology.

Total and high molecular weight but not trimeric or hexameric forms of adiponectin correlate with markers of the metabolic syndrome and liver injury in Thai subjects.

Y. Liu, A. Hanley, G. Sweeney, 2007, The Journal of clinical endocrinology and metabolism.

Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatment.

Y. Liu, A. Marette, A. Xu, 2009, American journal of physiology. Endocrinology and metabolism.

Effects of moderate electrical stimulation on reactive species production by primary rat skeletal muscle cells: Cross talk between superoxide and nitric oxide production

R. Curi, S. Hirabara, T. Pithon-Curi, 2012, Journal of cellular physiology.

Regulatory Connections between Iron and Glucose Metabolism

G. Sweeney, C. Fillebeen, K. Pantopoulos, 2020, International journal of molecular sciences.

Equilibrative nucleoside transporter 1 plays an essential role in cardioprotection.

M. Eguchi, G. Sweeney, D. Choi, 2010, American journal of physiology. Heart and circulatory physiology.

Transport characteristics of HL-1 cells: a new model for the study of adenosine physiology in cardiomyocytes.

G. Sweeney, I. Coe, T. Liron, 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice

A. Xu, Yu Wang, Donghai Wu, 2012, Proceedings of the National Academy of Sciences.

Leptin prevents the metabolic effects of adiponectin in L6 myotubes

G. Sweeney, K. Dadson, X. Fang, 2009, Diabetologia.

Analysis of paradoxical observations on the association between leptin and insulin resistance

H. Koistinen, J. Zierath, G. Sweeney, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The molecular basis of the antidiabetic action of quercetin in cultured skeletal muscle cells and hepatocytes

F. Thong, G. Sweeney, P. Haddad, 2015, Pharmacognosy magazine.

APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice.

E. Kraegen, A. Xu, Yu Wang, 2009, Cell metabolism.

An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heart.

F. Thong, A. Xu, R. Palanivel, 2010, American journal of physiology. Endocrinology and metabolism.

APPL1 Counteracts Obesity-Induced Vascular Insulin Resistance and Endothelial Dysfunction by Modulating the Endothelial Production of Nitric Oxide and Endothelin-1 in Mice

A. Xu, Yu Wang, Donghai Wu, 2011, Diabetes.

Adiponectin Synthesis, Secretion and Extravasation from Circulation to Interstitial Space.

G. Sweeney, Meilian Liu, S. C. da Silva Rosa, 2021, Physiology.

Globular Adiponectin, Acting via AdipoR1/APPL1, Protects H9c2 Cells from Hypoxia/Reoxygenation-Induced Apoptosis

A. Xu, Donghai Wu, G. Sweeney, 2011, PloS one.

Title Globular adiponectin , acting via AdipoR 1 / APPL 1 , protects H 9 c 2 cells from hypoxia / reoxygenation-induced apoptosis

A. Xu, Donghai Wu, G. Sweeney, 2011 .

Empagliflozin Blunts Worsening Cardiac Dysfunction Associated With Reduced NLRP3 (Nucleotide-Binding Domain-Like Receptor Protein 3) Inflammasome Activation in Heart Failure

S. Verma, P. Light, J. Dyck, 2020, Circulation. Heart failure.

Biomarkers of insulin sensitivity and insulin resistance: Past, present and future

S. E. Park, G. Sweeney, Cheol-Young Park, 2015, Critical reviews in clinical laboratory sciences.

Adiponectin Mediated APPL1‐AMPK Signaling Induces Cell Migration, MMP Activation, and Collagen Remodeling in Cardiac Fibroblasts

A. Xu, G. Sweeney, K. Dadson, 2014, Journal of cellular biochemistry.

Lipocalin-2 deficiency attenuates insulin resistance associated with ageing and obesity Running title : Lipocalin-2 and insulin resistance

T. Mak, Yu Wang, G. Sweeney, 2010 .

Temporal activation of p70 S6 kinase and Akt1 by insulin: PI 3-kinase-dependent and -independent mechanisms.

R. Somwar, A. Klip, G. Sweeney, 1998, The American journal of physiology.

Skeletal muscle glucose metabolism and inflammation in the development of the metabolic syndrome

Y. Liu, A. Marette, G. Sweeney, 2014, Reviews in Endocrine and Metabolic Disorders.

Adiponectin Action: A Combination of Endocrine and Autocrine/Paracrine Effects

Y. Liu, G. Sweeney, K. Dadson, 2011, Front. Endocrin..

Mechanisms regulating energy metabolism by adiponectin in obesity and diabetes.

G. Sweeney, X. Fang, 2006, Biochemical Society transactions.

Participation of PI3K and atypical PKC in Na+-K+-pump stimulation by IGF-I in VSMC.

A. Klip, G. Sweeney, D. Li, 1999, The American journal of physiology.

Participation of PI3K and atypical PKC in Na+-K+-pump stimulation by IGF-I in VSMC.

Dailin Li, A. Klip, Qinghua Wang, 1999, American journal of physiology. Heart and circulatory physiology.

Emerging clinical and experimental evidence for the role of lipocalin‐2 in metabolic syndrome

J. H. Lee, Y. Jang, G. Sweeney, 2012, Clinical and experimental pharmacology & physiology.

Importance of Autophagy in Mediating Cellular Responses to Iron Overload in Cardiomyocytes

G. Sweeney, S. Cho, E. Tam, 2022, Reviews in Cardiovascular Medicine.

Title Lipocalin-2 induces NLRP 3 inflammasome activation via HMGB 1 induced TLR 4 signaling in heart tissue of mice under pressure overload challenge

B. Hinz, T. Mak, A. Xu, 2017 .

Lipocalin-2 induces NLRP3 inflammasome activation via HMGB1 induced TLR4 signaling in heart tissue of mice under pressure overload challenge.

B. Hinz, T. Mak, A. Xu, 2017, American journal of translational research.

Lipocalin‐2 (NGAL) Attenuates Autophagy to Exacerbate Cardiac Apoptosis Induced by Myocardial Ischemia

Eric W. Danielson, T. Mak, G. Sweeney, 2017, Journal of cellular physiology.

Lipocalin-2 inhibits autophagy and induces insulin resistance in H9c2 cells

G. Sweeney, Meng-Hsuan Han, Y. Chan, 2016, Molecular and Cellular Endocrinology.

Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency.

Ren-Ke Li, G. Sweeney, S. Turdi, 2015, Endocrinology.

Crosstalk between the heart and peripheral organs in heart failure

G. Sweeney, Erfei Song, James Won Suk Jahng, 2016, Experimental & Molecular Medicine.

Distinct metabolic and vascular effects of dietary triglycerides and cholesterol in atherosclerotic and diabetic mouse models.

M. Laakso, J. Després, Y. Deshaies, 2013, American journal of physiology. Endocrinology and metabolism.

Leptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis

G. Sweeney, D. Orlov, M. P. Lee, 2005, International Journal of Obesity.

Leptin Increases Expression and Activity of Matrix Metalloproteinase-2 and Does Not Alter Collagen Production in Rat Glomerular Mesangial Cells

G. Sweeney, S. Madani, Marian Pit-Siu Lee, 2005, Endocrine research.

Membrane-permeant Esters of Phosphatidylinositol 3,4,5-Trisphosphate*

R. Tsien, A. Klip, G. Sweeney, 1998, The Journal of Biological Chemistry.

Printed in U.S.A. Copyright © 2001 by The Endocrine Society High Leptin Levels Acutely Inhibit Insulin-Stimulated Glucose Uptake without Affecting Glucose Transporter 4 Translocation in L6 Rat Skeletal Muscle Cells

R. Somwar, R. Garg, A. Klip, 2022 .

Differential Effects of Phosphatidylinositol 3-Kinase Inhibition on Intracellular Signals Regulating GLUT4 Translocation and Glucose Transport*

R. Somwar, V. Randhawa, A. Klip, 2001, The Journal of Biological Chemistry.

Improved functional recovery to I/R injury in hearts from lipocalin-2 deficiency mice: restoration of mitochondrial function and phospholipids remodeling.

T. Mak, H. Tse, A. Xu, 2012, American journal of translational research.

Iron overload reduces adiponectin receptor expression via a ROS/FOXO1‐dependent mechanism leading to adiponectin resistance in skeletal muscle cells

Sean M. Gross, G. Sweeney, J. B. Kim, 2021, Journal of cellular physiology.

Regulation of SOCS-3 expression by leptin and its co-localization with insulin receptor in rat skeletal muscle cells

M. Eguchi, G. Sweeney, J. C. McDermott, 2007, Molecular and Cellular Endocrinology.

Models of type 2 diabetes

R. Somwar, G. Sweeney, X. Fang, 2005 .

Acute and chronic leptin treatment mediate contrasting effects on signaling, glucose uptake, and GLUT4 translocation in L6‐GLUT4myc myotubes

G. Sweeney, J. Kwan, Panteha Tajmir, 2003, Journal of cellular physiology.

Ischemia-Reperfusion Injury Leads to Distinct Temporal Cardiac Remodeling in Normal versus Diabetic Mice

M. Eguchi, K. Kang, Y. Jang, 2012, PloS one.

Iron induces insulin resistance in cardiomyocytes via regulation of oxidative stress

G. Sweeney, K. Pantopoulos, Erfei Song, 2019, Scientific Reports.

Adiponectin-induced ERK and Akt Phosphorylation Protects against Pancreatic Beta Cell Apoptosis and Increases Insulin Gene Expression and Secretion*

Aamir Suhail, M. Wheeler, G. Sweeney, 2010, The Journal of Biological Chemistry.

Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

A. Lin, A. Xu, G. Sweeney, 2011, Diabetes.

Correlation of circulating full‐length visfatin (PBEF/NAMPT) with metabolic parameters in subjects with and without diabetes: a cross‐sectional study

Y. Liu, A. Hanley, G. Sweeney, 2008, Clinical endocrinology.

Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases

G. Sweeney, Y. Liu, V. Vu, 2019, Front. Endocrinol..

Adiponectin is required for cardiac MEF2 activation during pressure overload induced hypertrophy.

G. Sweeney, S. Turdi, J. C. McDermott, 2015, Journal of molecular and cellular cardiology.

Temporal and Molecular Analyses of Cardiac Extracellular Matrix Remodeling following Pressure Overload in Adiponectin Deficient Mice

B. Hinz, G. Sweeney, S. Turdi, 2015, PloS one.

Differential impact of adipokines derived from primary adipocytes of wild-type versus streptozotocin-induced diabetic rats on glucose and fatty acid metabolism in cardiomyocytes.

R. Palanivel, G. Sweeney, V. Vu, 2008, The Journal of endocrinology.

Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes.

M. Eguchi, A. Xu, Yu Wang, 2007, Cardiovascular research.

Distinct effects of short- and long-term leptin treatment on glucose and fatty acid uptake and metabolism in HL-1 cardiomyocytes.

M. Eguchi, R. Palanivel, G. Sweeney, 2006, Metabolism: clinical and experimental.

Temporal analysis of mechanisms leading to stimulation of glucose uptake in skeletal muscle cells by an adipokine mixture derived from primary rat adipocytes

F. Thong, G. Sweeney, T. Odisho, 2011, International Journal of Obesity.

Coculture with primary visceral rat adipocytes from control but not streptozotocin-induced diabetic animals increases glucose uptake in rat skeletal muscle cells: role of adiponectin.

A. Xu, G. Sweeney, V. Vu, 2007, Endocrinology.

Adiponectin stimulates Rho-mediated actin cytoskeleton remodeling and glucose uptake via APPL1 in primary cardiomyocytes.

A. Xu, R. Palanivel, G. Sweeney, 2014, Metabolism: clinical and experimental.

Lipocalin-2 Induces Cardiomyocyte Apoptosis by Increasing Intracellular Iron Accumulation*

M. Eguchi, A. Xu, Yu Wang, 2011, The Journal of Biological Chemistry.

The Adaptor Protein APPL2 Inhibits Insulin-Stimulated Glucose Uptake by Interacting With TBC1D1 in Skeletal Muscle

A. Xu, Yu Wang, Donghai Wu, 2014, Diabetes.

Control of fatty acid metabolism by leptin in L6 rat myoblasts is regulated by hyperinsulinemia

M. Eguchi, R. Palanivel, G. Sweeney, 2007, Journal of endocrinological investigation.

Insulin stimulation of K+ uptake in 3T3-L1 fibroblasts involves phosphatidylinositol 3-kinase and protein kinase C-zeta

R. Somwar, A. Klip, G. Sweeney, 1998, Diabetologia.

Regulation of insulin signalling, glucose uptake and metabolism in rat skeletal muscle cells upon prolonged exposure to resistin

R. Palanivel, G. Sweeney, A. Maida, 2005, Diabetologia.

Transendothelial movement of adiponectin is restricted by glucocorticoids.

G. Sweeney, M. Riddell, Pingnian He, 2017, The Journal of endocrinology.

Adiponectin action in skeletal muscle.

Y. Liu, G. Sweeney, 2014, Best practice & research. Clinical endocrinology & metabolism.

Implications of myocardial matrix remodeling by adipokines in obesity-related heart failure.

G. Sweeney, K. Schram, 2008, Trends in cardiovascular medicine.

Effects of the adiponectin mimetic compound ALY688 on glucose and fat metabolism in visceral and subcutaneous rat adipocytes

G. Sweeney, R. Ceddia, H. Sung, 2020, Adipocyte.

Unraveling the mechanisms linking obesity and heart failure: the role of adipokines

G. Sweeney, 2009, Expert review of endocrinology & metabolism.

Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice.

A. Xu, Yu Wang, Donghai Wu, 2009, Endocrinology.

Early Development of Calcific Aortic Valve Disease and Left Ventricular Hypertrophy in a Mouse Model of Combined Dyslipidemia and Type 2 Diabetes Mellitus

Y. Deshaies, P. Pibarot, A. Marette, 2014, Arteriosclerosis, thrombosis, and vascular biology.

An adiponectin-S1P axis protects against lipid induced insulin resistance and cardiomyocyte cell death via reduction of oxidative stress

G. Sweeney, K. Dadson, Amy Botta, 2019, Nutrition & Metabolism.

Globular adiponectin induces LKB1/AMPK-dependent glucose uptake via actin cytoskeleton remodeling.

M. Eguchi, A. Xu, G. Sweeney, 2013, Journal of molecular endocrinology.

Regulation of the Na+/K+-ATPase by insulin: Why and how?

A. Klip, G. Sweeney, 1998, Molecular and Cellular Biochemistry.

Adiponectin Stimulates Autophagy and Reduces Oxidative Stress to Enhance Insulin Sensitivity During High-Fat Diet Feeding in Mice

A. Xu, Timothy V Gabor, M. Scheid, 2014, Diabetes.

Creatine supplementation increases glucose oxidation and AMPK phosphorylation and reduces lactate production in L6 rat skeletal muscle cells

G. Sweeney, R. Ceddia, 2004, The Journal of physiology.

Understanding Mechanisms of Insulin Resistance in Diabetes and Obesity

G. Sweeney, 2022 .

Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes.

Ren-Ke Li, G. Sweeney, S. Madani, 2006, Cardiovascular research.

Altered Transendothelial Transport of Hormones as a Contributor to Diabetes

G. Sweeney, S. Kelly, Helen Chasiotis, 2014, Diabetes & metabolism journal.

Mechanisms and consequences of Na+,K+-pump regulation by insulin and leptin.

A. Klip, G. Sweeney, 2001, Cellular and molecular biology.

Identification of Circulating Endocan-1 and Ether Phospholipids as Biomarkers for Complications in Thalassemia Patients

N. Chattipakorn, S. Chattipakorn, G. Sweeney, 2021, Metabolites.

A Dominant-negative p38 MAPK Mutant and Novel Selective Inhibitors of p38 MAPK Reduce Insulin-stimulated Glucose Uptake in 3T3-L1 Adipocytes without Affecting GLUT4 Translocation*

R. Somwar, A. Klip, C. Rondinone, 2002, The Journal of Biological Chemistry.

Activation of p 38 Mitogen-Activated Protein Kinase and by Insulin and Contraction in Rat Skeletal Muscle Potential Role in the Stimulation of Glucose Transport

R. Somwar, A. Marette, A. Klip, 2000 .

GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase.

R. Somwar, A. Klip, G. Sweeney, 2001, The Biochemical journal.

Need for GLUT 4 Activation to Reach Maximum Effect of Insulin-Mediated Glucose Uptake in Brown Adipocytes Isolated From GLUT 4 myc-Expressing Mice

Z. Nawaz, A. Rudich, A. Klip, 2002 .

Cellular, structural and functional cardiac remodelling following pressure overload and unloading.

B. Hinz, Ren-Ke Li, G. Sweeney, 2016, International journal of cardiology.

The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation.

R. Somwar, A. Klip, G. Sweeney, 2001, Diabetes.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Circulating and PBMC Lp-PLA2 Associate Differently with Oxidative Stress and Subclinical Inflammation in Nonobese Women (Menopausal Status)

J. H. Lee, Y. Jang, Yonghee Lee, 2012, PloS one.

Holo-lipocalin-2–derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes

Derek J. Wilson, T. Mak, M. Wheeler, 2018, Proceedings of the National Academy of Sciences.

ALY688 elicits adiponectin-mimetic signaling and improves insulin action in skeletal muscle cells.

Sean M. Gross, A. Marette, G. Sweeney, 2021, American journal of physiology. Cell physiology.

Iron overload inhibits late stage autophagic flux leading to insulin resistance

R. Palanivel, G. Sweeney, R. Botelho, 2019, EMBO reports.

Association of Lp-PLA(2) activity and LDL size with interleukin-6, an inflammatory cytokine and oxidized LDL, a marker of oxidative stress, in women with metabolic syndrome.

J. H. Lee, J. Chae, G. Sweeney, 2011, Atherosclerosis.

Temporal activation of p 70 S 6 kinase and Akt 1 by insulin : PI 3-kinase-dependent and-independent mechanisms

R. Somwar, A. Klip, G. Sweeney, 1998 .

Adiponectin improves insulin sensitivity via activation of autophagic flux.

G. Sweeney, Suharto Chakma, Esther Rai, 2017, Journal of molecular endocrinology.

Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells

G. Sweeney, A. Hilliker, R. Ceddia, 2004, Cell proliferation.

Modulation of the cardiovascular system by leptin.

G. Sweeney, E. Abel, E. Abel, 2012, Biochimie.

Insulin mimetics in Urtica dioica: structural and computational analyses of Urtica dioica extracts

G. Sweeney, V. Vu, Michael B. Wheeler, 2010, Phytotherapy research : PTR.

Leptin signalling.

G. Sweeney, 2002, Cellular signalling.

Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration.

F. Thong, G. Sweeney, X. Fang, 2011, Endocrinology.

Leptin protects H9c2 rat cardiomyocytes from H2O2‐induced apoptosis

M. Eguchi, G. Sweeney, Eyun-Jung Shin, 2008, The FEBS journal.

Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts.

I. Dixon, R. Palanivel, G. Sweeney, 2008, Journal of molecular and cellular cardiology.

Insulin increases gelatinase activity in rat glomerular mesangial cells via ERK‐ and PI‐3 kinase‐dependent signalling

G. Sweeney, M. P. Lee, 2006, Diabetes, obesity & metabolism.

Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes

F. Thong, G. Sweeney, K. Schram, 2010, Cellular & Molecular Biology Letters.

FGF21–Sirtuin 3 Axis Confers the Protective Effects of Exercise Against Diabetic Cardiomyopathy by Governing Mitochondrial Integrity

Fuyu Duan, Z. Xia, A. Xu, 2022, Circulation.

Cardiac remodeling in obesity.

G. Sweeney, E. Abel, S. Litwin, 2008, Physiological reviews.

Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge.

J. Klawitter, G. Sweeney, D. Choi, 2011, Life sciences.

Healthy and sustainable diets for future generations

A. Drewnowski, P. Broun, G. Sweeney, 2018, Journal of the science of food and agriculture.

Use of 2-dimensional cell monolayers and 3-dimensional microvascular networks on microfluidic devices shows that iron increases transendothelial adiponectin flux via inducing ROS production.

G. Sweeney, J. Jeon, Seunggyu Kim, 2020, Biochimica et biophysica acta. General subjects.

GUT MICROBIOME AND METABOLIC HEALTH

G. Sweeney, J. Schertzer, K. Pantopoulos, 2021 .

dipyridamoleHL-1 by cardioprotective drugs dilazep and Inhibition of glucose uptake in murine cardiomyocyte cell

G. Sweeney, P. Bilan, I. Coe, 2016 .

Inhibition of glucose uptake in murine cardiomyocyte cell line HL-1 by cardioprotective drugs dilazep and dipyridamole.

G. Sweeney, P. Bilan, I. Coe, 2004, American journal of physiology. Heart and circulatory physiology.

The association between PGC-1α and Alzheimer's disease

Juhyun Song, G. Sweeney, 2016, Anatomy & cell biology.

Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptake

G. Sweeney, A. Xu, Z. Wang, 2009, Diabetologia.

Direct effects of adipokines on the heart: focus on adiponectin

G. Sweeney, Min Park, 2013, Heart Failure Reviews.

Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans.

E. Kraegen, A. Xu, Yu Wang, 2007, Clinical chemistry.

Insulin increases plasma membrane content and reduces phosphorylation of Na(+)-K(+) pump alpha(1)-subunit in HEK-293 cells.

A. Klip, G. Sweeney, V. Canfield, 2001, American journal of physiology. Cell physiology.

Tracking adiponectin biodistribution via fluorescence molecular tomography indicates increased vascular permeability after streptozotocin-induced diabetes.

B. Hinz, J. Peterson, G. Sweeney, 2019, American Journal of Physiology. Endocrinology and Metabolism.

The role of adiponectin signaling in metabolic syndrome and cancer

M. Scheid, G. Sweeney, 2014, Reviews in Endocrine and Metabolic Disorders.

Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia

C. Borchers, G. Sweeney, T. Hawke, 2023, International journal of molecular sciences.

Metabolomic profiling as a useful tool for diagnosis and treatment of chronic disease: focus on obesity, diabetes and cardiovascular diseases

J. H. Lee, G. Sweeney, O. Y. Kim, 2013, Expert review of cardiovascular therapy.

An Inhibitor of p38 Mitogen-activated Protein Kinase Prevents Insulin-stimulated Glucose Transport but Not Glucose Transporter Translocation in 3T3-L1 Adipocytes and L6 Myotubes*

R. Somwar, A. Klip, G. Sweeney, 1999, The Journal of Biological Chemistry.

Obesity and Cardiac Dysfunction

G. Sweeney, E. Abel, S. Litwin, 2011 .

Changing Prevalence of Obesity and Link to Cardiovascular Disease

G. Sweeney, S. Litwin, E. Abel, 2008 .

Palmitate Induces ER Stress and Autophagy in H9c2 Cells: Implications for Apoptosis and Adiponectin Resistance

G. Sweeney, S. Turdi, Min Park, 2015, Journal of cellular physiology.

Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality.

J. Freedman, M. Al-Omran, S. Verma, 2008, American journal of physiology. Endocrinology and metabolism.

Activation of the glucose transporter GLUT4 by insulin.

R. Somwar, A. Klip, G. Sweeney, 2002, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise

G. Sweeney, M. Riddell, V. Vu, 2007, Diabetes/metabolism research and reviews.

Resistin inhibits glucose uptake in L6 cells independently of changes in insulin signaling and GLUT4 translocation.

G. Sweeney, N. Begum, J. Kwan, 2003, American journal of physiology. Endocrinology and metabolism.

Metabolomic profiling in liver of adiponectin-knockout mice uncovers lysophospholipid metabolism as an important target of adiponectin action.

Gary D Bader, Ruth Isserlin, Ruth Isserlin, 2015, The Biochemical journal.

Intracellular Delivery of Phosphatidylinositol (3,4,5)-Trisphosphate Causes Incorporation of Glucose Transporter 4 into the Plasma Membrane of Muscle and Fat Cells without Increasing Glucose Uptake*

L. Foster, G. Prestwich, R. Somwar, 2004, Journal of Biological Chemistry.

Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice.

Z. Nawaz, A. Rudich, A. Klip, 2002, Diabetes.

Activation of p38 mitogen-activated protein kinase alpha and beta by insulin and contraction in rat skeletal muscle: potential role in the stimulation of glucose transport.

R. Somwar, A. Marette, A. Klip, 2000, Diabetes.

Regulation of Iron and Its Significance in Obesity and Complications

G. Sweeney, Y. Chan, H. Sung, 2014 .

Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase.

Xuefei Gao, P. Liu, Maikun Teng, 2011, The Biochemical journal.

Carnitine palmitoyltransferase 1 A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase

Xuefei Gao, Maikun Teng, Yu Wang, 2011 .

Leptin increases cardiomyocyte hyperplasia via extracellular signal-regulated kinase- and phosphatidylinositol 3-kinase-dependent signaling pathways.

Ren-Ke Li, G. Sweeney, R. Ceddia, 2004, Endocrinology.

Leptin increases cardiomyocyte hyperplasia via ERK- and PI 3-kinase-dependent signaling pathways

Ren-Ke Li, G. Sweeney, R. Ceddia, 2004 .

The furan fatty acid metabolite CMPF is elevated in diabetes and induces β cell dysfunction.

I. G. Fantus, W. Jia, F. Dai, 2014, Cell metabolism.

The genetic and metabolic determinants of cardiovascular complications in type 2 diabetes: recent insights from animal models and clinical investigations.

M. Laakso, J. Després, M. Uusitupa, 2013, Canadian journal of diabetes.

Functional and Mechanistic Integration of Infection and the Metabolic Syndrome

G. Sweeney, P. Sommer, 2010, Korean diabetes journal.

Adiponectin Corrects High-Fat Diet–Induced Disturbances in Muscle Metabolomic Profile and Whole-Body Glucose Homeostasis

Y. Liu, Y. Deshaies, A. Xu, 2013, Diabetes.

Iron metabolism and regulation by neutrophil gelatinase-associated lipocalin in cardiomyopathy.

G. Sweeney, Y. Chan, H. Sung, 2015, Clinical science.

Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers

J. Grigull, J. Zhao, G. Sweeney, 2017, Scientific Reports.

APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.

Ren-Ke Li, A. Xu, Donghai Wu, 2013, American journal of physiology. Endocrinology and metabolism.

Delivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasis.

A. Xu, G. Sweeney, S. Sen, 2013, American journal of physiology. Endocrinology and metabolism.

Globular adiponectin increases GLUT4 translocation and glucose uptake but reduces glycogen synthesis in rat skeletal muscle cells

R. Somwar, G. Sweeney, R. Ceddia, 2004, Diabetologia.

GLUT 4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells : potential activation of GLUT 4 via p 38 mitogen-activated protein kinase

R. Somwar, A. Klip, G. Sweeney, 2022 .

Cardiovascular complications of diabetes: recent insights in pathophysiology and therapeutics

A. Marette, G. Sweeney, 2011, Expert review of endocrinology & metabolism.

Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr-/-ApoB100/100 mice.

B. Jensen, A. Marette, M. Blais, 2020, Atherosclerosis.

Lipocalin-2 Deficiency Attenuates Insulin Resistance Associated With Aging and Obesity

T. Mak, A. Xu, Yu Wang, 2010, Diabetes.

Cardiovascular effects of leptin

G. Sweeney, 2010, Nature Reviews Cardiology.

Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells

G. Sweeney, A. Abdul-Sater, H. Sung, 2023, Cell Death & Disease.

Role of Mitochondrial Iron Overload in Mediating Cell Death in H9c2 Cells

G. Sweeney, A. Abdul-Sater, N. H. Lam, 2022, Cells.

Diabetes influences cardiac extracellular matrix remodelling after myocardial infarction and subsequent development of cardiac dysfunction

M. Eguchi, Ren-Ke Li, G. Sweeney, 2012, Journal of cellular and molecular medicine.

Mechanisms of Cardiac Fibrosis and Heart Failure

G. Sweeney, K. Dadson, V. Kovacevic, 2015 .

Leptin attenuates hypoxia/reoxygenation‐induced activation of the intrinsic pathway of apoptosis in rat H9c2 cells

G. Sweeney, Xi-Long Zheng, Eyun-Jung Shin, 2009, Journal of cellular physiology.

Serum ferritin is linked with aortic stiffness in apparently healthy Korean women.

G. Sweeney, W. Y. Kim, K. Lee, 2010, Critical pathways in cardiology.

Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota

A. Marette, G. Sweeney, Thibault V. Varin, 2022, Basic & clinical pharmacology & toxicology.

A unique conformational distortion mechanism drives Lipocalin 2 binding to bacterial siderophores.

Derek J. Wilson, Philip E. Johnson, G. Sweeney, 2020, ACS chemical biology.

An adiponectin-S1P autocrine axis protects skeletal muscle cells from palmitate-induced cell death

G. Sweeney, Amy Botta, N. H. Lam, 2020, Lipids in Health and Disease.

Inhibitory effects of terrein on lung cancer cell metastasis and angiogenesis

G. Sweeney, C. Peng, Paiwan Buachan, 2021, Oncology reports.

The adiponectin analogue ALY688-SR attenuates diaphragm fibrosis, atrophy and mitochondrial stress in a mouse model of Duchenne muscular dystrophy

G. Sweeney, T. Hawke, C. G. Perry, 2023, bioRxiv.

Cardiac Autophagy Deficiency Attenuates ANP Production and Disrupts Myocardial-Adipose Crosstalk Leading to Increased Fat Accumulation and Metabolic Dysfunction.

M. Wheeler, G. Sweeney, R. Ceddia, 2020, Diabetes.

Emerging role of autophagy in mediating widespread actions of ADIPOQ/adiponectin

A. Xu, G. Sweeney, 2015, Autophagy.

Memory impairment in the D2.mdx mouse model of Duchenne muscular dystrophy is prevented by the adiponectin receptor agonist ALY688

G. Sweeney, C. G. Perry, A. Abdul-Sater, 2023, Experimental physiology.

Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease

G. Sweeney, Fan Ying, S. Cho, 2023, Biomedical journal.

MitoNEET prevents iron overload‐induced insulin resistance in H9c2 cells through regulation of mitochondrial iron

G. Sweeney, H. Sung, Eddie Tam, 2023, Journal of cellular physiology.

Development and validation of a meal quality index with applications to NHANES 2005-2014

G. Sweeney, H. Green, Daniela Prozorovscaia, 2020, PloS one.

TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt.

A. Xu, Yu Wang, Donghai Wu, 2013, The Biochemical journal.

Regulation of the Na,K-pump by leptin in 3T3-L1 fibroblasts.

A. Klip, G. Sweeney, W. Niu, 2000, Endocrinology.

High Leptin Levels Acutely Inhibit Insulin-Stimulated Glucose Uptake without Affecting Glucose Transporter 4 Translocation in L6 Rat Skeletal Muscle Cells

R. Somwar, R. Garg, G. Sweeney, 2001 .