Darrin P. Smith

发表

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

Kei Sakamoto, Alan Ashworth, A. Ashworth, 2005, The EMBO journal.

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

Charis Eng, Zhou Songyang, Kermit L. Carraway, 1995, Nature.

Erratum: Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours (Human Molecular Genetics (1994) 3 (237-241))

B. Ponder, C. Healey, L. Mulligan, 1994 .

Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation

A. Ashworth, J. Reis-Filho, B. Weigelt, 2009, The Journal of pathology.

C-cell and thyroid epithelial tumours and altered follicular development in transgenic mice expressing the long isoform of MEN 2A RET

B. Ponder, D. Winton, Darrin P. Smith, 2001, Oncogene.

Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes and Hirschsprung disease

C. Eng, Darrin P. Smith, B. Ponder, 1994, Journal of Cell Science.

RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2

T. Pawson, B. Ponder, G. Gish, 1997, Oncogene.

Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation

B. Ponder, M. Borrello, M. Pierotti, 1998, Oncogene.

A glucose-6-phosphate dehydrogenase G 6 PD splice site consensus sequence mutation associated with G 6 PD enzyme deficiency

Darrin P. Smith, E. D. Williams, G. Thomas, 1997 .

Expression of a dominant negative retinoic acid receptor γ in Xenopus embryos leads to partial resistance to retinoic acid

E. Jones, C. Mason, Darrin P. Smith, 1994, Roux's archives of developmental biology.

Precocious synthesis of a thyroid hormone receptor inXenopus embryos causes hormone-dependent developmental abnormalities

E. Jones, Darrin P. Smith, R. Old, 1992, Roux's archives of developmental biology.

Germline mutation of RET codon 883 in two cases of de novo MEN 2B

B. Ponder, Darrin P. Smith, C. Houghton, 1997, Oncogene.

Molecular pathways for lymphangiogenesis and their role in human disease.

K. Alitalo, S. Stacker, Darrin P. Smith, 2007, Novartis Foundation symposium.

Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma

B. Ponder, C. Healey, L. Mulligan, 1995, Genes, chromosomes & cancer.

MYC levels govern hematopoietic tumor type and latency in transgenic mice.

A. W. Harris, S. Cory, Darrin P. Smith, 2006, Blood.

T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haemopoietic expression of MYC

A. W. Harris, S. Cory, Darrin P. Smith, 2005, Oncogene.

Deficiency of the Wnt receptor Ryk causes multiple cardiac and outflow tract defects

M. Kirby, D. Newgreen, M. Halford, 2018, Growth factors.

GDNF signalling through the Ret receptor tyrosine kinase

B. Ponder, F. Costantini, M. Saarma, 1996, Nature.

Regulation of the Wnt signalling component PAR1A by the Peutz–Jeghers syndrome kinase LKB1

A. Ashworth, J. Spicer, Darrin P. Smith, 2003, Oncogene.

Low frequency of germline mutations in the RET proto‐oncogene in patients with apparently sporadic medullary thyroid carcinoma

C Eng, C. Healey, L. Mulligan, 1995, Clinical endocrinology.

No mutation at codon 918 of the RET gene in a family with multiple endocrine neoplasia type 2B

C. Eng, Darrin P. Smith, B. Ponder, 1995, Clinical endocrinology.

Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells

S. Baylin, B. Ponder, Darrin P. Smith, 1998, Oncogene.

Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours.

C. Healey, L. Mulligan, C. Eng, 1994, Human molecular genetics.

A novel nuclear receptor superfamily member in Xenopus that associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor

D P Smith, C S Mason, E A Jones, 1994, Nucleic Acids Res..

RET activation by germline MEN2A and MEN2B mutations.

M. Borrello, C. Eng, M. Pierotti, 1995, Oncogene.

A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC.

B. Ponder, M. Zvelebil, C. Healey, 1995, Oncogene.

Multiple mRNA isoforms of the human RET proto-oncogene generated by alternate splicing.

B. Ponder, C. Healey, L. Mulligan, 1995, Oncogene.

The MEN II syndromes and the role of the ret proto-oncogene.

B. Ponder, Darrin P. Smith, D. Smith, 1996, Advances in cancer research.

Expression of multiple endocrine neoplasia 2B RET in neuroblastoma cells alters cell adhesion in vitro, enhances metastatic behavior in vivo, and activates Jun kinase.

B. Ponder, J. Hancock, A. Peaston, 1997, Cancer research.

Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas.

S. Chew, C. Healey, L. Mulligan, 1995, Journal of medical genetics.