B. Thorens

R. Gruetter, G. Labouèbe, H. Lei, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Glucose uptake, utilization, and signaling in GLUT2-null islets.

B. Thorens, P. Dupraz, M. Guillam, 2000, Diabetes.

In vivo effect of murine recombinant interleukin 3 on early hemopoietic progenitors

V. Kindler, B. Thorens, P. Vassalli, 1987, European journal of immunology.

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

B. Thorens, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Cloning and Functional Expression of the Human Islet GLP-1 Receptor: Demonstration That Exendin-4 Is an Agonist and Exendin-(9–39) an Antagonist of the Receptor

Shaoping Deng, C. Widmann, P. Morel, 1993, Diabetes.

Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes

E. Bonifacio, M. Mann, A. Brunner, 2020, bioRxiv.

Inhibition of glucose‐induced insulin secretion by long‐term preexposure of pancreatic islets to leptin

B. Thorens, R. Roduit, Raphaël Roduit, 1997, FEBS letters.

Glucose transporter gene expression in early mouse embryos.

N. Copeland, D. Gilbert, N. Jenkins, 1991, Development.

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization.

C. Kahn, M. Birnbaum, P. Vollenweider, 2003, The Journal of clinical investigation.

VAMP‐2 and cellubrevin are expressed in pancreatic beta‐cells and are essential for Ca(2+)‐but not for GTP gamma S‐induced insulin secretion.

B. Thorens, C. Montecucco, M. Palmer, 1995, The EMBO journal.

Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization (*)

D. Pipeleers, H. Heimberg, B. Thorens, 1995, The Journal of Biological Chemistry.

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

M. Birnbaum, B. Thorens, F. Beermann, 1998, Nature Genetics.

Molecular Physiology of Glucose Transporters

H. Lodish, B. Thorens, M. J. Charron, 1990, Diabetes Care.

Glucagon receptor family (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

D. Drucker, L. Miller, D. Bataille, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators.

H. Lodish, D. James, M. Birnbaum, 2002, American journal of physiology. Endocrinology and metabolism.

Plac8 is required for White Adipocyte Differentiation in vitro and Cell Number Control in vivo

B. Thorens, Maria Jimenez-Preitner, Xavier Berney, 2012, PloS one.

Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells

H. Moch, B. Thorens, W. Dolci, 2013, Proceedings of the National Academy of Sciences.

Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domains.

L. Orci, H. Lodish, B. Thorens, 1989, Science.

Regulated expression of GLUT2 in diabetes studied in transplanted pancreatic beta cells.

B. Thorens, R. Roduit, 1994, Biochemical Society transactions.

Resistance to Diet-Induced Obesity and Associated Metabolic Perturbations in Haploinsufficient Monocarboxylate Transporter 1 Mice

P. Magistretti, L. Pellerin, J. Stehle, 2013, PloS one.

Metabolic effects of diets differing in glycaemic index depend on age and endogenous GIP

M. Tschöp, A. Pfeiffer, M. Weickert, 2010 .

Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice

M. Tschöp, A. Pfeiffer, M. Weickert, 2009, Diabetologia.

Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice.

M. Tschöp, A. Pfeiffer, M. Ristow, 2008, American journal of physiology. Endocrinology and metabolism.

Regulation of adaptive behaviour during fasting by hypothalamic Foxa2

Ferdinand von Meyenn, M. Stoffel, J. Howell, 2009, Nature.

Phagocytosis and inflammatory stimuli induce GM-CSF mRNA in macrophages through posttranscriptional regulation

J. Mermod, B. Thorens, P. Vassalli, 1987, Cell.

Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice.

D. Chappard, M. Baslé, B. Thorens, 2013, Bone.

Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function

B. Thorens, G. Leibowitz, J. Gertsch, 2022, Nature Communications.

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

F. Pattou, K. Timper, M. Donath, 2017, Nature Immunology.

Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction

W. Wahli, H. Guillou, M. Defernez, 2016, Scientific Reports.

Lipoprotein Lipase and Leptin Are Accumulated in Different Secretory Compartments in Rat Adipocytes*

K. Kandror, B. Thorens, S. Fried, 2001, The Journal of Biological Chemistry.

Regulated exocytosis of an H+/myo‐inositol symporter at synapses and growth cones

P. Steiner, M. Uldry, B. Thorens, 2004, The EMBO journal.

PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.

F. Ashcroft, P. Rorsman, W. Krek, 2008, Genes & development.

Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse

G. Rutter, N. Janel, L. Rachdi, 2022, Cells.

Glucose transporters in the 21 st Century

B. Thorens, M. Mueckler, 2010 .

Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development

J. Auwerx, T. Lüscher, C. Matter, 2013, Basic Research in Cardiology.

Immunolocalization of GLUTX1 in the Testis and to Specific Brain Areas and Vasopressin- Containing Neurons.

M. Uldry, B. Thorens, M. Ibberson, 2002, Endocrinology.

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice

E. Wright, V. Kepe, J. Barrio, 2016, The Journal of physiology.

A missing sugar prevents glucose entry: a new twist on insulin secretion.

B. Thorens, 2006, Cell metabolism.

The Hepatoportal Glucose Sensor

B. Thorens, 2004 .

The facilitative glucose transporter 2: pathophysiological role in mouse and human

M. Foretz, B. Thorens, 2003 .

Simple‐sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2‐null mice

B. Thorens, A. Leturque, É. Brot-Laroche, 2003, The Journal of physiology.

GLUT2 is a high affinity glucosamine transporter

M. Uldry, B. Thorens, M. Ibberson, 2002, FEBS letters.

A gene knockout approach in mice to identify glucose sensors controlling glucose homeostasis

B. Thorens, 2002, Pflügers Archiv.

IMPAIRED GLUCOSE SENSING AS INITIATOR OF METABOLIC DYSFUNCTIONS

B. Thorens, 2002 .

Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway.

B. Thorens, M. Hosokawa, 2002, American journal of physiology. Endocrinology and metabolism.

Normal kinetics of intestinal glucose absorption in the absence of GLUT2: Evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum

K. Jungermann, R. Burcelin, B. Thorens, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Differential Sensitivity of GLUT1- and GLUT2-Expressing β Cells to Streptozotocin

B. Thorens, W. Dolci, M. Hosokawa, 2001 .

Pathophysiology of Glut2 in Diabetes Mellitus

B. Thorens, 2001 .

Liver Hyperplasia and Paradoxical Regulation of Glycogen Metabolism and Glucose-sensitive Gene Expression in GLUT2-null Hepatocytes

R. Burcelin, B. Thorens, M. Guillam, 2000, The Journal of Biological Chemistry.

Transgenic Reexpression of GLUT1 or GLUT2 in Pancreatic β Cells Rescues GLUT2-null Mice from Early Death and Restores Normal Glucose-stimulated Insulin Secretion*

R. Burcelin, B. Thorens, F. Beermann, 2000, The Journal of Biological Chemistry.

Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes.

R. Burcelin, B. Thorens, M. Guillam, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment.

J. Leahy, G. Weir, B. Thorens, 1992, The Journal of clinical investigation.

Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats.

H. Lodish, J. Leahy, S. Bonner-Weir, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Sequence of the mouse liver glucose transporter.

H. Lodish, B. Thorens, K. Suzue, 1989, Nucleic acids research.

LKB1 and AMPK differentially regulate pancreatic β-cell identity

G. Rutter, Y. Dor, F. Reimann, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion

B. Thorens, R. Mynatt, I. Lopez-Mejia, 2020, Molecular metabolism.

Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets

M. Bugliani, P. Marchetti, B. Thorens, 2018, Diabetologia.

Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes.

B. Thorens, 1996, The American journal of physiology.

Expression of the human erythrocyte glucose transporter in Escherichia coli.

H. Lodish, H. Kaback, B. Thorens, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues

B. Thorens, L. Fajas, K. Huber, 2020, EMBO reports.

Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension.

P. Vollenweider, C. Sartori, C. Perrin, 2004, Diabetes.

Insulin Resistance, Hyperlipidemia, and Hypertension in Mice Lacking Endothelial Nitric Oxide Synthase

P. Vollenweider, C. Sartori, R. Burcelin, 2001, Circulation.

Leptin inhibits directly glucocorticoid secretion by normal human and rat adrenal gland.

G. Waeber, B. Thorens, F. Pralong, 1998, Endocrinology.

Leptin Inhibits Directly Glucocorticoid Secretion by Normal Human and Rat Adrenal Gland* * This work was supported by a grant from the Swiss National Science Foundation (No. 3100-050748.97/1).

G. Waeber, B. Thorens, F. Pralong, 1998, Endocrinology.

A toggle for type 2 diabetes?

B. Thorens, 2006, The New England journal of medicine.

Restricted expression of the erythroid/brain glucose transporter isoform to perivenous hepatocytes in rats. Modulation by glucose.

H. Lodish, B. Thorens, M. Tal, 1990, The Journal of clinical investigation.

Recovery of Glucose-Induced Insulin Secretion in a Rat Model of NIDDM Is Not Accompanied by Return of the B-Cell GLUT2 Glucose Transporter

J. Leahy, S. Bonner-Weir, G. Weir, 1992, Diabetes.

Type 2 Diabetes, SGLT2 Inhibitors, and Glucose Secretion.

A. Hattersley, B. Thorens, 2015, The New England journal of medicine.

Clinic al Implic a tions of Ba s ic R e se ar ch

A. Hattersley, B. Thorens, 2015 .

Role of Lipoproteins on Pancreatic Islet Cells Survival, Function and Proliferation

M. Donath, B. Thorens, 2020 .

Encapsulated, Genetically Engineered Cells, Secreting Glucagon‐like Peptide‐1 for the Treatment of Non‐insulin‐dependent Diabetes Mellitus

S. Germain, R. Burcelin, B. Thorens, 1999, Annals of the New York Academy of Sciences.

Glucose‐dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): Cellular localization, lesion‐affected expression, and impaired regenerative axonal growth

H. Müller, B. Thorens, B. Buhren, 2009, Journal of neuroscience research.

Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells

T. Hansen, O. Pedersen, J. Holst, 1998, Diabetologia.

Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function

O. Madsen, M. Poutanen, T. Gorman, 2015, Diabetes.

The Glucagon Receptor Family

D. Drucker, L. Miller, B. Thorens, 2000 .

LKB1 and AMPK differentially regulate pancreatic β-cell identity

G. Rutter, Y. Dor, F. Reimann, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Expression and Functional Activity of Glucagon, Glucagon-Like Peptide I, and Glucose-Dependent Insulinotropic Peptide Receptors in Rat Pancreatic Islet Cells

D. Pipeleers, H. Heimberg, B. Thorens, 1996, Diabetes.

Expression of the Glucagon‐Like Peptide‐1 Receptor Gene in Rat Brain

B. Thorens, E. Blázquez, J. Chowen, 1996, Journal of neurochemistry.

Impaired Glucose Homeostasis in Mice Lacking the α1b-Adrenergic Receptor Subtype*

M. Foretz, C. Perrin, R. Burcelin, 2004, Journal of Biological Chemistry.

Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.

W. Wahli, S. Kersten, C. Knauf, 2006, Endocrinology.

Glucagon-Like Peptide-I and the Control of Insulin Secretion in the Normal State and in NIDDM

G. Waeber, B. Thorens, 1993, Diabetes.

Heterologous Desensitization of the Glucagon-like Peptide-1 Receptor by Phorbol Esters Requires Phosphorylation of the Cytoplasmic Tail at Four Different Sites*

C. Widmann, B. Thorens, W. Dolci, 1996, The Journal of Biological Chemistry.

The role of sodium-coupled glucose co-transporter 3 in the satiety effect of portal glucose sensing.

F. Delaere, G. Mithieux, B. Thorens, 2013, Molecular metabolism.

Sensing of glucose in the brain.

B. Thorens, 2012, Handbook of experimental pharmacology.

Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence.

D. Drucker, B. Thorens, S. Efrat, 1998, Endocrinology.

The SLC2 family of facilitated hexose and polyol transporters

M. Uldry, B. Thorens, 2004, Pflügers Archiv.

Reduced beta-cell glucose transporter in new onset diabetic BB rats.

L. Orci, H. Lodish, B. Thorens, 1990, The Journal of clinical investigation.

The loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors

G. Waeber, B. Thorens, P. Nicod, 1997, Molecular and Cellular Endocrinology.

Exendin-(9-39) Is an Inverse Agonist of the Murine Glucagon-Like Peptide-1 Receptor: Implications for Basal Intracellular Cyclic Adenosine 3',5'-Monophosphate Levels and β-Cell Glucose Competence* *This work was supported by Grant 31-46958.96 from the Swiss National Science Foundation (to B.T.).

D. Drucker, B. Thorens, S. Efrat, 1998, Endocrinology.

PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance

J. Montani, M. Wymann, B. Thorens, 2011, Proceedings of the National Academy of Sciences.

Sex-Specific Control of Fat Mass and Counterregulation by Hypothalamic Glucokinase

G. Labouèbe, B. Thorens, D. Basco, 2016, Diabetes.

The GIuco-Incretin Hormone Glucagon-Like Peptide-1 and Its β-Cell Receptor

B. Thorens, 1994 .

Differential localization of two glucose transporter isoforms in rat kidney.

H. Lodish, Dennis Brown, B. Thorens, 1990, The American journal of physiology.

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes

E. Bonifacio, M. Knip, D. Dunger, 2022, Trials.

Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy

M. Loeken, B. Thorens, R. Li, 2007, Diabetologia.

Peroxisome Proliferator-Activated Receptor-- Null Mice Have Increased White Adipose Tissue Glucose Utilization , GLUT 4 , and Fat Mass : Role in Liver and Brain

W. Wahli, S. Kersten, C. Knauf, 2006 .

GLUT2 surface expression and intracellular transport via the constitutive pathway in pancreatic beta cells and insulinoma: evidence for a block in trans-Golgi network exit by brefeldin A

B. Thorens, N. Dériaz, N. Gérard, 1993, The Journal of cell biology.

Developmental expression and cellular localization of glucose transporter molecules during mouse preimplantation development.

B. Thorens, M. J. Charron, L. Jarett, 1992, Development.

Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate.

C. Widmann, B. Thorens, W. Dolci, 1996, Molecular endocrinology.

Internalization and homologous desensitization of the GLP-1 receptor depend on phosphorylation of the receptor carboxyl tail at the same three sites.

C. Widmann, B. Thorens, W. Dolci, 1997, Molecular endocrinology.

Comparative effects of GLP-1-(7-36) amide, oxyntomodulin and glucagon on rabbit gastric parietal cell function.

D. Bataille, F. Hollande, B. Thorens, 1995, European journal of pharmacology.

Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas.

B. Thorens, W. Dolci, C. Widmann, 1995, The Biochemical journal.

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

R. Burcelin, B. Thorens, W. Dolci, 2000, Diabetes.

Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion

B. Thorens, S. Croizier, Maxime Jan, 2022, Molecular metabolism.

Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study

B. Thorens, L. Pénicaud, C. Leloup, 2004, Journal of Chemical Neuroanatomy.

Glutamine Stimulates Biosynthesis and Secretion of Insulin-like Growth Factor 2 (IGF2), an Autocrine Regulator of Beta Cell Mass and Function*

B. Thorens, M. Cornu, H. Modi, 2014, The Journal of Biological Chemistry.

Loss of glucose-induced insulin secretion and GLUT2 expression in transplanted β-cells

S. Bonner-Weir, G. Weir, B. Thorens, 1995, Diabetes.

Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice

D. Hanahan, H. Lodish, B. Thorens, 1992, Molecular and cellular biology.

Physiology of GLP-1 - Lessons from Glucoincretin Receptor Knockout Mice

B. Thorens, 2004, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

PPAR b / d affects pancreatic b cell mass and insulin secretion in mice

P. Chambon, W. Wahli, G. Rutter, 2018 .

PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.

P. Chambon, W. Wahli, G. Rutter, 2012, The Journal of clinical investigation.

Of fat, β cells, and diabetes.

B. Thorens, 2011, Cell metabolism.

Heterogeneous secretion of individual B cells in response to D-glucose and to nonglucidic nutrient secretagogues.

P. Meda, B. Thorens, D. Bosco, 1995, The American journal of physiology.

Perspectives in Diabetes Glucagon-Like Peptide-l and the Control of Insulin Secretion in the Normal State and in NIDDM

B. Thorens, 2022 .

Incretin Receptor Null Mice Reveal Key Role of GLP-1 but Not GIP in Pancreatic Beta Cell Adaptation to Pregnancy

D. Drucker, B. Thorens, P. Flatt, 2014, PloS one.

Allogeneic beta-islet cells correct diabetes and resist immune rejection.

R. Zinkernagel, P. Aebischer, B. Thorens, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines.

B. Thorens, W. Dolci, E. Bürki, 1994, Molecular pharmacology.

Incretins: what is known, new and controversial in 2013?

R. Burcelin, B. Thorens, Bernard Thorens, 2013, Diabetes & metabolism.

Structure and Function of the Glucagon-Like Peptide-1 Receptor

C. Widmann, B. Thorens, 1996 .

EuroDia: a beta-cell gene expression resource

C. V. Jongeneel, S. Bergmann, I. Xenarios, 2010 .

Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding.

M. Foretz, B. Thorens, D. Tarussio, 2006, Diabetes.

The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic β cells

S. L. Gurun, J. Haefliger, G. Waeber, 2003, Journal of Cell Science.

The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines.

B. Thorens, T. Mandrup-Poulsen, C. Bonny, 2003, Cytokine.

Original article EuroDia: a beta-cell gene expression resource

S. Bergmann, I. Xenarios, M. Bugliani, 2010 .

Expression of facilitative glucose transporter in rat liver and choroid plexus

R. Grobholz, B. Thorens, H. Hacker, 1991, Histochemistry.

Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells.

H. Lodish, B. Thorens, D. Brown, 1990, The American journal of physiology.

Fostering improved human islet research: a European perspective

M. McCarthy, L. Groop, R. Scharfmann, 2019, Diabetologia.

Liver glucose transporter: a basolateral protein in hepatocytes and intestine and kidney cells.

H. Lodish, B. Thorens, D. Brown, 1990, The American journal of physiology.

Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line.

D. Bataille, B. Thorens, L. Gros, 1993 .

Expression cloning of the pancreatic J 8 cell receptor for the gluco-incretin hormone glucagon-like peptide 1 ( insulin secretion / non-insulin-dependent diabetes mellitus / entero-insular axis / G proteins / cAMP )

B. Thorens, 2022 .

Intracellular targeting of GLUT4 in transfected insulinoma cells: evidence for association with constitutively recycling vesicles distinct from synaptophysin and insulin vesicles.

B. Thorens, J. Roth, Bernard Thorens, 1996, Journal of cell science.

Allogeneic β-islet cells correct diabetes and resist immune rejection

R. Zinkernagel, P. Aebischer, B. Thorens, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress

B. Thorens, N. Irwin, P. Flatt, 2014, PloS one.

Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion

G. Labouèbe, B. Thorens, Maxime Jan, 2022, Nature Communications.

In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist

G. Rutter, P. Marchetti, T. Vilsbøll, 2022, Diabetes, obesity & metabolism.

Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia

G. Labouèbe, B. Thorens, Sevasti Gaspari, 2022, bioRxiv.

Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores

G. Rutter, P. Marchetti, B. Thorens, 2016, Diabetes.

EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis

G. Labouèbe, B. Thorens, S. Croizier, 2020, PLoS biology.

Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk

Elizabeth T. Cirulli, Amalio Telenti, Tim D. Spector, 2019, Cell metabolism.

GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis.

G. Labouèbe, C. Lamy, B. Thorens, 2018, Methods in molecular biology.

Vitamin D--dependent calcium binding protein: immunocytochemical localization in chick kidney.

L. Orci, B. Thorens, A. Norman, 1981, Science.

GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting

G. Labouèbe, B. Thorens, S. Croizier, 2022, Scientific Reports.

cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells.

B. Thorens, W. Dolci, P. Dupraz, 2002, Diabetes.

Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice

R. Burcelin, B. Thorens, M. Pende, 2000, Nature.

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

V. Kindler, B. Thorens, P. Vassalli, 1986, Proceedings of the National Academy of Sciences of the United States of America.

sugar/polyol transport facilitators Nomenclature of the GLUT/SLC2A family of

H. Lodish, D. James, M. Birnbaum, 2011 .

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

L. Schild, B. Thorens, G. Buell, 1994, Nature.

Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion

Bernard Thorens, B. Thorens, P. Vassalli, 1986, Nature.

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cells.

H. Lodish, H. Kaback, B. Thorens, 1988, Cell.

The SLC2 (GLUT) family of membrane transporters.

B. Thorens, M. Mueckler, 2013, Molecular aspects of medicine.

Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.

J. Haefliger, G. Waeber, R. Bucala, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet.

Bernard Thorens, R. Burcelin, B. Thorens, 2002, American journal of physiology. Endocrinology and metabolism.

Title The peroxisomal enzyme L-PBE is required to preventthe dietary toxicity of medium-chain Fatty acids

W. Wahli, V. Zoete, H. Riezman, 2017 .

The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids.

W. Wahli, V. Zoete, H. Riezman, 2013, Cell reports.

Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy

B. Thorens, D. Firsov, O. Bonny, 2009, Proceedings of the National Academy of Sciences.

Mouse GLUT9: evidences for a urate uniporter.

K. Geering, B. Thorens, D. Firsov, 2009, American journal of physiology. Renal physiology.

Evidence from oocyte expression that the erythrocyte water channel is distinct from band 3 and the glucose transporter.

A. Verkman, S. Alper, B. Thorens, 1991, The Journal of clinical investigation.

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members

H. Joost, B. Thorens, 2001, Molecular membrane biology.

Plasma triacylglycerols are biomarkers of β-cell function in mice and humans

J. Weitz, M. Solimena, B. Thorens, 2021, Molecular metabolism.

Glucose transporters in the 21st Century.

B. Thorens, M. Mueckler, 2010, American journal of physiology. Endocrinology and metabolism.

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells

H. Lodish, H. Kaback, B. Thorens, 1988, Cell.

Glucagon-like peptide-1 and control of insulin secretion.

B. Thorens, 1995, Diabete & metabolisme.

Transcript Profiling Suggests That Differential Metabolic Adaptation of Mice to a High Fat Diet Is Associated with Changes in Liver to Muscle Lipid Fluxes*

M. Delorenzi, L. Falquet, P. Farmer, 2004, Journal of Biological Chemistry.

R. Burcelin, B. Thorens, F. Pralong, 2022 .

Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

E. Bonifacio, M. Mann, D. Aust, 2021, Nature Metabolism.

Brain glucose sensing in homeostatic and hedonic regulation

G. Labouèbe, B. Thorens, L. Steinbusch, 2015, Trends in Endocrinology & Metabolism.

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

E. Bonifacio, U. Boggi, E. Petretto, 2017, Diabetologia.

GLUT2, glucose sensing and glucose homeostasis

B. Thorens, 2015, Diabetologia.

GLUT2 in pancreatic and extra-pancreatic gluco-detection

B. Thorens, 2001, Molecular membrane biology.

cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells.

B. Thorens, W. Dolci, P. Dupraz, 2002, Diabetes.

Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion – A step towards precision medicine

B. Thorens, C. Magnan, M. Ibberson, 2019, Molecular metabolism.

Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.

Ioannis Xenarios, Frédéric Fumeron, Robin Liechti, 2017, Cell reports.

Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion

I. Xenarios, R. Scharfmann, G. Rutter, 2017, Molecular metabolism.

The required beta cell research for improving treatment of type 2 diabetes

B. Thorens, 2013, Journal of internal medicine.

Oxidative Phosphorylation Flexibility in the Liver of Mice Resistant to High-Fat Diet–Induced Hepatic Steatosis

B. Thorens, E. Abel, M. Ibberson, 2011, Diabetes.

Peroxisomal and Microsomal Lipid Pathways Associated with Resistance to Hepatic Steatosis and Reduced Pro-inflammatory State*

Matej Oresic, Carine Poussin, Mark Ibberson, 2010, The Journal of Biological Chemistry.

Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta-cells.

V. Mooser, G. Waeber, C. Widmann, 2009, Molecular endocrinology.

GLUTX1, a Novel Mammalian Glucose Transporter Expressed in the Central Nervous System and Insulin-sensitive Tissues*

M. Uldry, B. Thorens, M. Ibberson, 2000, The Journal of Biological Chemistry.

Clic4, a novel protein that sensitizes β-cells to apoptosisa

D. Eizirik, B. Thorens, F. Brozzi, 2015, Molecular metabolism.

Correction: Gluco-Incretins Regulate Beta-Cell Glucose Competence by Epigenetic Silencing of Fxyd3 Expression

P. Marchetti, L. Marselli, J. Chatton, 2014, PLoS ONE.

Gluco-Incretins Regulate Beta-Cell Glucose Competence by Epigenetic Silencing of Fxyd3 Expression

P. Marchetti, L. Marselli, J. Chatton, 2014, PloS one.

Expression of an Uncleavable N-terminal RasGAP Fragment in Insulin-secreting Cells Increases Their Resistance toward Apoptotic Stimuli without Affecting Their Glucose-induced Insulin Secretion*

G. Waeber, C. Widmann, B. Thorens, 2005, Journal of Biological Chemistry.

Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells.

G. Christofori, U. Cavallaro, P. Fiorina, 2003, Endocrinology.

SOCS-1 Protein Prevents Janus Kinase/STAT-dependent Inhibition of β Cell Insulin Gene Transcription and Secretion in Response to Interferon-γ*

B. Thorens, W. Dolci, P. Dupraz, 2001, The Journal of Biological Chemistry.

Expression of the NH2-Terminal Fragment of RasGAP in Pancreatic β-Cells Increases Their Resistance to Stresses and Protects Mice From Diabetes

J. Hornung, C. Widmann, B. Thorens, 2009, Diabetes.

Uric acid transport and disease.

Bernard Thorens, B. Thorens, A. So, 2010, The Journal of clinical investigation.

Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice

B. Thorens, F. Santoni, Irina Kolotuev, 2021, Molecular metabolism.

Title : The SLC 2 ( GLUT ) family of membrane transporters

B. Thorens, M. Mueckler, 2022 .

Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group.

O. Ljungqvist, A. Gossum, C. Pichard, 2017, Clinical nutrition.

Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk

T. Spector, E. Kirkness, N. Shah, 2019, Cell metabolism.

Profound perturbation of the human metabolome by obesity

T. Spector, E. Kirkness, N. Shah, 2018, bioRxiv.

Fgf15 Neurons of the Dorsomedial Hypothalamus Control Glucagon Secretion and Hepatic Gluconeogenesis

G. Labouèbe, B. Thorens, S. Croizier, 2021, Diabetes.

A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion

B. Thorens, M. Ibberson, F. Burdet, 2016, Cell reports.

Protein Kinase A-dependent Phosphorylation of GLUT2 in Pancreatic Cells (*)

P. Meda, D. Pipeleers, B. Thorens, 1996, The Journal of Biological Chemistry.

Immunocytochemical localization of the vitamin D-dependent calcium binding protein in chick duodenum

L. Orci, B. Thorens, A. Norman, 1982, The Journal of cell biology.

No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse.

B. Thorens, A. Sarre, D. Firsov, 2015, Kidney international.

Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors.

Tanya Hansotia, D. Drucker, C. Wollheim, 2004, The Journal of clinical investigation.

Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.

B. Viollet, M. Foretz, F. Andreelli, 2008, Cell metabolism.

Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength

D. Chappard, B. Thorens, N. Irwin, 2014, Osteoporosis International.

Structural and molecular characterization of paraventricular thalamic glucokinase‐expressing neuronal circuits in the mouse

B. Thorens, S. Croizier, S. Quenneville, 2022, The Journal of comparative neurology.

Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.

U. Boggi, G. Rutter, P. Froguel, 2020, Cell reports.

Ins1Cre knock-in mice for beta cell-specific gene recombination

B. Thorens, J. Ferrer, M. Maestro, 2014, Diabetologia.

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

T. Heise, M. Köhler, F. Schliess, 2015, Nature Medicine.

Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis.

C. Hölscher, B. Thorens, V. Gault, 2011, Journal of neurophysiology.

Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor.

D. Drucker, R. Burcelin, B. Thorens, 2001, Diabetes.

Long-lasting antidiabetic effect of a dipeptidyl peptidase IV-resistant analog of glucagon-like peptide-1.

R. Burcelin, B. Thorens, W. Dolci, 1999, Metabolism: clinical and experimental.

GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration

P. MacDonald, D. Egli, Kunal Kumar, 2020, Science Translational Medicine.

Identification of a mammalian H+‐myo‐inositol symporter expressed predominantly in the brain

J. Chatton, M. Uldry, B. Thorens, 2001, The EMBO journal.

Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study

L. Groop, T. Suvitaival, G. Rutter, 2021, Diabetes.

Central Glucose Sensing and Control of Food Intake and Energy Homeostasis

B. Thorens, L. Mounien, 2011 .

α-cell glucokinase suppresses glucose-regulated glucagon secretion

P. Rorsman, B. Thorens, P. Herrera, 2018, Nature Communications.

Facilitated glucose transporters in epithelial cells.

B. Thorens, B Thorens, 1993, Annual review of physiology.

Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass

G. Rutter, G. da Silva Xavier, B. Thorens, 2014, Human molecular genetics.

International Union of Pharmacology. XXXV. The Glucagon Receptor Family

D. Drucker, L. Miller, D. Bataille, 2003, Pharmacological Reviews.

Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis.

M. Foretz, B. Thorens, C. Magnan, 2014, The Journal of clinical investigation.

Glut2‐dependent glucose‐sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons

M. Foretz, B. Thorens, L. Mounien, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Glucose sensing and the pathogenesis of obesity and type 2 diabetes

B. Thorens, Bernard Thorens, 2008, International Journal of Obesity.

Brain glucose sensing, counterregulation, and energy homeostasis.

B. Thorens, M. Dallaporta, Nell Marty, 2007, Physiology.

Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors.

M. Foretz, B. Thorens, F. Beermann, 2005, The Journal of clinical investigation.

Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain—an immunohistochemical study

B. Thorens, L. Pénicaud, C. Leloup, 2004, Journal of Chemical Neuroanatomy.

Hepatic glucose sensing is required to preserve β cell glucose competence.

F. Schütz, M. Foretz, B. Thorens, 2013, The Journal of clinical investigation.

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

M. Birnbaum, B. Thorens, F. Beermann, 1998, Nature Genetics.

Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons.

M. Uldry, B. Thorens, M. Ibberson, 2002, Endocrinology.

MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.

M. Prentki, B. Thorens, S. Rome, 2012, The Journal of clinical investigation.

The roles of granulocyte-macrophage colony-stimulating factor and interleukin 3 in stromal cell-mediated hemopoiesis in vivo.

V. Kindler, B. Thorens, P. Vassalli, 1988, Experimental hematology.

Receptor-mediated phagocytosis by macrophages induces a calcium-dependent transient increase in c-fos transcription.

D. Belin, B. Thorens, J. Vassalli, 1989, Oncogene.

Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice.

M. Daudon, Dominique Bazin, A. Dessombz, 2013, American journal of physiology. Renal physiology.

Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study

L. Groop, T. Suvitaival, G. Rutter, 2021, Diabetologia.

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.

J. H. Johnson, H. Lodish, C. Newgard, 1990, The Journal of biological chemistry.

Glucagon-like Peptide-1 Increases β-Cell Glucose Competence and Proliferation by Translational Induction of Insulin-like Growth Factor-1 Receptor Expression*

Bernard Thorens, Rohit N. Kulkarni, R. Kulkarni, 2010, The Journal of Biological Chemistry.

Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop

Carine Poussin, Bernard Thorens, C. Widmann, 2009, Diabetes.

A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production

G. Mithieux, B. Thorens, M. Soty, 2023, Molecular metabolism.

Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice.

P. Vollenweider, R. Burcelin, B. Thorens, 2003, Swiss medical weekly.

Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.

B. Viollet, M. Foretz, F. Andreelli, 2005, Diabetes.

Cloning, Functional Expression, and Chromosomal Localization of the Human Pancreatic Islet Glucose-Dependent Insulinotropic Polypeptide Receptor

P. Froguel, B. Thorens, E. Hani, 1995, Diabetes.

The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse

U. Maskos, S. Pons, B. Thorens, 2020, Biomolecules.

Bioinformatics-Driven Identification and Examination of Candidate Genes for Non-Alcoholic Fatty Liver Disease

T. Hansen, O. Pedersen, S. Brunak, 2011, PloS one.

Neural regulation of pancreatic islet cell mass and function

B. Thorens, 2014, Diabetes, obesity & metabolism.

Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption

G. Labouèbe, B. Thorens, S. Croizier, 2021, iScience.

Central control of glucose homeostasis: the brain--endocrine pancreas axis.

B. Thorens, 2010, Diabetes & metabolism.

Glucose responsive neurons of the paraventricular thalamus control sucrose-seeking behavior

G. Labouèbe, B. Thorens, B. Boutrel, 2016, Nature Neuroscience.

Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin.

B. Thorens, W. Dolci, M. Hosokawa, 2001, Biochemical and biophysical research communications.

Brain glucose sensing and neural regulation of insulin and glucagon secretion

B. Thorens, 2011, Diabetes, obesity & metabolism.

GLP-1(9-36) mediates the glucagonostatic effect of GLP-1 by promiscuous activation of the glucagon receptor

P. Rorsman, G. Ladds, F. Reimann, 2019 .

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice.

R. Burcelin, B. Thorens, W. Dolci, 2000, Diabetes.

Shifting the paradigm of islet inflammation—good guy or bad guy?

D. Accili, S. Seino, C. Boitard, 2013, Diabetes, obesity & metabolism.

Involvement of 4E-BP1 in the Protection Induced by HDLs on Pancreatic β-Cells

V. Mooser, G. Waeber, C. Widmann, 2009 .

GLUT8 Is Dispensable for Embryonic Development but Influences Hippocampal Neurogenesis and Heart Function

J. Haefliger, M. Membrez, B. Thorens, 2006, Molecular and Cellular Biology.

Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia

M. Evans, B. Thorens, A. McNeilly, 2021, Diabetologia.

SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney

K. Seuwen, B. Thorens, O. Bonny, 2018, Pflügers Archiv - European Journal of Physiology.

Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia

G. Labouèbe, B. Thorens, Sevasti Gaspari, 2023, bioRxiv.

The hyperstimulated β‐cell: prelude to diabetes?

D. Accili, S. Seino, C. Boitard, 2012, Diabetes, obesity & metabolism.

HomeostasisGlucose Sensing, Counterregulation, and Energy

A. Kalsbeek, D. Belsham, B. Thorens, 2015 .

Homeostasis Brain Glucose Sensing , Counterregulation , and Energy

B. Thorens, M. Dallaporta, Nell Marty, 2007 .

Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion.

R. Burcelin, B. Thorens, 2001, Diabetes.

Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis

P. J. Larsen, B. Thorens, 2004, Current opinion in clinical nutrition and metabolic care.

Identification of biomarkers for glycaemic deterioration in type 2 diabetes

L. Groop, V. Gudnason, T. Suvitaival, 2023, Nature communications.

Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.

J. Ledford, M. Uldry, B. Thorens, 2011, Cell metabolism.

α-cell glucokinase suppresses glucose-regulated glucagon secretion

P. Rorsman, B. Thorens, P. Herrera, 2018, Nature Communications.

Normal Glucagon Signaling and β-Cell Function After Near-Total α-Cell Ablation in Adult Mice

P. Meda, A. Wiederkehr, C. Wollheim, 2011, Diabetes.

Exendin-4 Protects β-Cells From Interleukin-1β–Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway

G. Waeber, M. Ferdaoussi, C. Widmann, 2008, Diabetes.

Exendin-4 Protects -Cells From Interleukin-1-Induced Apoptosis by Interfering With the c-Jun NH 2 -Terminal

C. Widmann, B. Thorens, Jiang-Yan Yang, 2008 .

Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes

B. Thorens, A. Dinkova-Kostova, A. McNeilly, 2023, Diabetologia.

Glucagon receptor family in GtoPdb v.2021.3

D. Drucker, L. Miller, D. Bataille, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion

D. Accili, B. Thorens, G. Bell, 2022, Diabetes.

The SLC2 family of facilitated hexose and polyol transporters

M. Uldry, B. Thorens, 2004, Pflügers Archiv.

Mechanisms of glucose sensing and multiplicity of glucose sensors.

B. Thorens, Bernard Thorens, 2004, Annales d'endocrinologie.

EphrinB1 modulates glutamatergic inputs into POMC neurons and controls glucose homeostasis

B. Thorens, S. Croizier, A. Picard, 2020, bioRxiv.

Hypoglycemia-activated GLUT2 neurons of the nucleus tractus solitarius stimulate vagal activity and glucagon secretion.

G. Labouèbe, C. Lamy, J. Chatton, 2014, Cell metabolism.

Gene expression signature predicts rate of type 1 diabetes progression

Maria K. Jaakkola, E. Bonifacio, C. de Beaufort, 2023, EBioMedicine.

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation

B. Viollet, G. Labouèbe, M. Foretz, 2020, Diabetes.

Molecular biology of gluco-incretin function

B. Thorens, Sonia Klinger, 2008 .

Promiscuous receptor activation mediates glucagonostatic effects of GLP-1(9-36) and GLP-1(7-36)

P. Rorsman, G. Ladds, F. Reimann, 2019, bioRxiv.

Klf6 protects β-cells against insulin resistance-induced dedifferentiation

B. Thorens, M. Ibberson, D. Basco, 2020, Molecular metabolism.

SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney

K. Seuwen, B. Thorens, O. Bonny, 2018, Pflügers Archiv - European Journal of Physiology.

Molecular and cellular physiology of GLUT-2, a high-Km facilitated diffusion glucose transporter.

B. Thorens, 1992, International review of cytology.

Bone marrow pre‐B lymphocytes synthesize immunoglobulin mu chains of membrane type with different properties and intracellular pathways.

B. Thorens, P. Vassalli, M. Schulz, 1985, The EMBO journal.

[Gluco-incretin hormones in insulin secretion and diabetes].

B. Thorens, 2003, Medecine sciences : M/S.

Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14.1T

Rolf Gruetter, Hongxia Lei, Bernard Thorens, 2010, NMR in biomedicine.

Distinct Classes of Central GLUT2-Dependent Sensors Control Counterregulation and Feeding

B. Thorens, Isabelle Bady, Nell Marty, 2006, Diabetes.

Different Transcriptional Control of Metabolism and Extracellular Matrix in Visceral and Subcutaneous Fat of Obese and Rimonabant Treated Mice

B. Thorens, C. Poussin, K. Minehira, 2008, PloS one.

Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes

D. Huglo, F. Pattou, H. Koepsell, 2023, iScience.

Pseudospatial transcriptional gradient analysis of hypothalamic ependymal cells: towards a new tanycyte classification

F. Santoni, A. Messina, B. Thorens, 2023, bioRxiv.

Neuronal regulation of glucagon secretion and gluconeogenesis

B. Thorens, 2022, Journal of diabetes investigation.

Signal transduction and desensitization of the glucagon-like peptide-1 receptor.

C. Widmann, B. Thorens, 1996, Acta physiologica Scandinavica.

In Vivo Conditional Pax4 Overexpression in Mature Islet β-Cells Prevents Stress-Induced Hyperglycemia in Mice

P. Meda, K. He, C. Wollheim, 2011, Diabetes.

Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells.

G. Christofori, U. Cavallaro, P. Fiorina, 2003, Endocrinology.

Targeting the Brain to Cure Type 2 Diabetes

B. Thorens, 2019, Diabetes.

Maintenance of Hepatic Nuclear Factor 6 in Postnatal Islets Impairs Terminal Differentiation and Function of β-Cells

I. Artner, R. Stein, B. Thorens, 2006, Diabetes.

Sugar-Sensitive Hypothalamic Neurons Glucose-Induced Intracellular Ion Changes in

M. Evans, M. Foretz, B. Thorens, 2015 .

Cloning and Functional Expression of the Human Islet GLP-1 Receptor: Demonstration That Exendin-4 Is an Agonist and Exendin-(9–39) an Antagonist of the Receptor

Shaoping Deng, B. Thorens, L. Bühler, 1993, Diabetes.

Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.

J. Ledford, M. Uldry, B. Thorens, 2011, Cell metabolism.

Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas.

C. Widmann, B. Thorens, W. Dolci, 1995, The Biochemical journal.

The required beta cell research for improving treatment of type 2 diabetes

B. Thorens, 2013, Journal of internal medicine.

Uric acid transport and disease.

B. Thorens, A. So, 2010, The Journal of clinical investigation.

Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin.

R. Burcelin, B. Thorens, F. Pralong, 2003, Endocrinology.

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

F. Pattou, K. Timper, M. Donath, 2017, Nature Immunology.

Peroxisomal and Microsomal Lipid Pathways Associated with Resistance to Hepatic Steatosis and Reduced Pro-inflammatory State*

J. Beckmann, M. Orešič, B. Thorens, 2010, The Journal of Biological Chemistry.

D. Drucker, B. Thorens, S. Efrat, 1998, Endocrinology.

Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice.

P. Vollenweider, R. Burcelin, B. Thorens, 2003, Swiss medical weekly.

Novel biomarkers for glycaemic deterioration in type 2 diabetes: an IMI RHAPSODY study

L. Groop, V. Gudnason, T. Suvitaival, 2021, medRxiv.