H. Miyoshi

发表

Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.

Hiroyuki Miyoshi, Makoto M Taketo, M. Seldin, 2002, Cancer research.

Oncogenic function of the homeobox A13-long noncoding RNA HOTTIP-insulin growth factor-binding protein 3 axis in human gastric cancer

Hiroyuki Miyoshi, Yukio Nakamura, Chee-Yin Chai, 2016, Oncotarget.

Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors.

B. Torbett, I. Verma, H. Miyoshi, 1999, Science.

Generation of transgenic non-human primates with germline transmission

H. Okano, H. Suemizu, T. Nomura, 2009, Nature.

Self-formation of functional adenohypophysis in three-dimensional culture

Hiroyuki Miyoshi, Yoshiki Sasai, Yutaka Oiso, 2011, Nature.

Intestinal Tumorigenesis in Compound Mutant Mice of both Dpc4(Smad4) and Apc Genes

Hiroyuki Miyoshi, Makoto M Taketo, M. Seldin, 1998, Cell.

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

Atsushi Miyawaki, Hiroyuki Miyoshi, Takeshi Imamura, 2008, Cell.

Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity.

Y. Yoshioka, Y. Tsutsumi, S. Nakagawa, 2008, Journal of immunological methods.

Nuclear and cytoplasmic c‐Ski differently modulate cellular functions

K. Miyazono, K. Miyazawa, T. Imamura, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Comparison of gene-trapping efficiency between retroviral and lentiviral vectors in mouse embryonic stem cells.

H. Miyoshi, Tomoyuki Yamaguchi, Azusa Morikawa, 2012, Biochemical and biophysical research communications.

Lentivirus vectors expressing short hairpin RNAs against the U3-overlapping region of HIV nef inhibit HIV replication and infectivity in primary macrophages.

J. Inoue, H. Miyoshi, Naoki Yamamoto, 2006, Blood.

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

A. Iwama, H. Nakauchi, S. Karlsson, 2011, Cell.

Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.

H. Miyoshi, Takao Nakamura, A. Kanatani, 2006, The Journal of endocrinology.

Establishment of induced pluripotent stem cells from human neonatal tissues

Yukio Nakamura, H. Miyoshi, Tsuyoshi Fujioka, 2010, Human Cell.

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination.

H. Kurumizaka, Koichi Sato, D. Schindler, 2017, Molecular cell.

Pitx2 Prevents Osteoblastic Transdifferentiation of Myoblasts by Bone Morphogenetic Proteins*

H. Aburatani, K. Miyazono, S. Maeda, 2008, Journal of Biological Chemistry.

Selective Down-Regulation of Th2 Cytokines by C-Terminal Binding Protein 2 in Human T Cells

O. Kaminuma, A. Mori, H. Miyoshi, 2010, International Archives of Allergy and Immunology.

Suppressive role of C-terminal binding protein 1 in IL-4 synthesis in human T cells.

O. Kaminuma, A. Mori, H. Miyoshi, 2009, Biochemical and biophysical research communications.

Generation and Targeting of Human Tumor-Specific Tc1 and Th1 Cells Transduced with a Lentivirus Containing a Chimeric Immunoglobulin T-Cell Receptor

M. Kuroki, H. Katoh, H. Miyoshi, 2004, Cancer Research.

A Lentiviral cDNA Library Employing Lambda Recombination Used To Clone an Inhibitor of Human Immunodeficiency Virus Type 1-Induced Cell Death

Takeshi Yoshida, H. Miyoshi, Y. Koyanagi, 2004, Journal of Virology.

Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy.

H. Miyoshi, K. Kawana, M. Nakanishi, 2018, Cell stem cell.

Necessary and sufficient role for a mitosis skip in senescence induction.

M. Nakanishi, E. Hara, N. Ohtani, 2014, Molecular cell.

Effective inhibition of cell growth and invasion of melanoma by combined suppression of BRAF (V599E) and Skp2 with lentiviral RNAi

K. Taira, M. Miyagishi, H. Miyoshi, 2006, International journal of cancer.

Control of Oxidative Stress and Generation of Induced Pluripotent Stem Cell-like Cells by Jun Dimerization Protein 2

C. Chai, Yukio Nakamura, Deng-Chyang Wu, 2013, Cancers.

RNA interfering approach for clarifying the PPARγ pathway using lentiviral vector expressing short hairpin RNA

Y. Tsutsumi, S. Nakagawa, T. Mayumi, 2004, FEBS letters.

Advances in Brief Gastrointestinal Hamartomatous Polyposis in Lkb 1 Heterozygous Knockout Mice 1

M. Seldin, M. Taketo, H. Miyoshi, 2002 .

genes cells by cell engineering with tumor peptide-specific T-cell receptor Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1

H. Ikeda, H. Miyoshi, Y. Oka, 2008 .

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.

H. Ikeda, H. Miyoshi, Y. Oka, 2005, Blood.

Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer.

K. Obama, M. Taketo, S. Shirasawa, 2021, Cancer letters.

Recent progress in the research of suicide gene therapy for malignant glioma

H. Okano, H. Miyoshi, M. Toda, 2019, Neurosurgical Review.

Generation of human tumor-specific, HLA class I-restricted Th1 and Tc1 cells by cell engineering with tumor peptide-specific T cell receptor genes

H. Ikeda, H. Miyoshi, Y. Oka, 2005 .

Generation of Cloned Mice by Direct Nuclear Transfer from Natural Killer T Cells

H. Miyoshi, H. Wakao, N. Ogonuki, 2005, Current Biology.

Repopulating Activity of Ex Vivo‐Expanded Murine Hematopoietic Stem Cells Resides in the CD48−c‐Kit+Sca‐1+Lineage Marker− Cell Population

H. Miyoshi, H. Ichikawa, K. Horiguchi, 2008, Stem cells.

Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference

H. Mizuguchi, T. Hayakawa, K. Taira, 2005, Gene Therapy.

Naive-like Conversion Overcomes the Limited Differentiation Capacity of Induced Pluripotent Stem Cells*

H. Miyoshi, Kimiko Inoue, Shogo Matoba, 2013, The Journal of Biological Chemistry.

Jdp2-deficient granule cell progenitors in the cerebellum are resistant to ROS-mediated apoptosis through xCT/Slc7a11 activation

K. Nagata, Yukio Nakamura, Deng-Chyang Wu, 2020, Scientific Reports.

Detection of thyroid system-disrupting chemicals using in vitro and in vivo screening assays in Xenopus laevis.

N. Shimada, K. Yamauchi, H. Miyoshi, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

RFWD 3-Mediated Ubiquiti nation Promotes Timely Removal of Both RPA and RAD 51 from DNA Damage Sites to Facilitate Homologous Recombination Graphical

H. Kurumizaka, Koichi Sato, D. Schindler, 2022 .

Peroxisome Proliferator-activated Receptor γ-mediated Regulation of Neural Stem Cell Proliferation and Differentiation*

T. Mayumi, Y. Terauchi, T. Kadowaki, 2006, Journal of Biological Chemistry.

Critical roles of the cAMP‐responsive element‐binding protein‐mediated pathway in disorganized epithelial phenotypes caused by mitochondrial dysfunction

K. Nose, M. Shibanuma, H. Miyoshi, 2012, Cancer science.

Advances in Brief Hepatocellular Carcinoma Caused by Loss of Heterozygosity in Lkb 1 Gene Knockout Mice 1

M. Seldin, M. Taketo, M. Imamura, 2002 .

Necdin Controls Proliferation of White Adipocyte Progenitor Cells

Y. Tseng, H. Miyoshi, K. Yoshikawa, 2012, PloS one.

Stable embryonic stem cell lines in rabbits: potential small animal models for human research.

H. Miyoshi, K. Yokoyama, N. Ogonuki, 2008, Reproductive biomedicine online.

Characteristics of a thyroid hormone responsive reporter gene transduced into a Xenopus laevis cell line using lentivirus vector.

K. Yamauchi, H. Miyoshi, S. Sugiyama, 2005, General and comparative endocrinology.

Rapid and efficient generation of lentivirally gene-modified dendritic cells from DC progenitors with bone marrow stromal cells.

Y. Ikeda, H. Miyoshi, Y. Kawakami, 2002, Journal of immunological methods.

Efficient lentiviral transduction of human cord blood CD34(+) cells followed by their expansion and differentiation into dendritic cells.

H. Miyoshi, K. Ando, T. Shimizu, 2001, Experimental hematology.

Clonal analysis of thymus-repopulating cells presents direct evidence for self-renewal division of human hematopoietic stem cells.

Mamoru Ito, H. Miyoshi, K. Ando, 2006, Blood.

Gastric and Duodenal Polyps in Smad 4 ( Dpc 4 ) Knockout Mice 1

M. Taketo, H. Miyoshi, M. Oshima, 1999 .

Naïve-like conversion enhances the difference in innate in vitro differentiation capacity between rabbit ES cells and iPS cells

L. Yasmin, H. Miyoshi, Shogo Matoba, 2014, The Journal of Reproduction and Development.

Differential Contribution of NFATc2 and NFATc1 to TNF-α Gene Expression in T Cells1

A. Miyawaki, O. Kaminuma, H. Miyoshi, 2008, The Journal of Immunology.

Retronectin enhances lentivirus-mediated gene delivery into hematopoietic progenitor cells.

Sinae Kim, Yong-soo Lee, Hyunjoo Lee, 2009, Biologicals : journal of the International Association of Biological Standardization.

Fumagillin suppresses HIV‐1 infection of macrophages through the inhibition of Vpr activity

H. Miyoshi, A. Koito, Tomoyuki Yamaguchi, 2006, FEBS letters.

Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice.

H. Miyoshi, T. Stappenbeck, Nicholas A. Manieri, 2012, Gastroenterology.

Inhibitory effect of human TRIM5alpha on HIV-1 production.

M. Kondo, J. Chen, H. Miyoshi, 2010, Microbes and infection.

Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells

K. Obama, M. Taketo, H. Miyoshi, 2022, Cells.

Expression of osterix inhibits bone morphogenetic protein-induced chondrogenic differentiation of mesenchymal progenitor cells

K. Miyazono, S. Maeda, T. Imamura, 2009, Journal of Bone and Mineral Metabolism.

Differential contribution of NFATc2 and NFATc1 to TNF-alpha gene expression in T cells.

A. Miyawaki, O. Kaminuma, H. Miyoshi, 2008, Journal of immunology.

Gene therapy using genome‐edited iPS cells for targeting malignant glioma

O. Sampetrean, H. Saya, J. Kohyama, 2022, Bioengineering & translational medicine.

Proliferation of rat small hepatocytes requires follistatin expression

H. Miyoshi, N. Tanimizu, T. Mitaka, 2012, Journal of cellular physiology.

Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

H. Okano, H. Nakauchi, J. Kohyama, 2017, Stem cell reports.

Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector.

F. Gage, I. Verma, F. Gage, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Fucci-guided purification of hematopoietic stem cells with high repopulating activity.

A. Miyawaki, Asako Sakaue-Sawano, H. Miyoshi, 2015, Biochemical and biophysical research communications.

Mouse Cloning Using a Drop of Peripheral Blood1

O. Ohara, H. Miyoshi, N. Ogonuki, 2013, Biology of reproduction.

Cellular Dynamics of Mouse Trophoblast Stem Cells: Identification of a Persistent Stem Cell Type1

K. Abe, H. Miyoshi, Kimiko Inoue, 2016, Biology of reproduction.

Peroxisome proliferator-activated receptor gamma-mediated regulation of neural stem cell proliferation and differentiation.

T. Mayumi, Y. Terauchi, T. Kadowaki, 2006, The Journal of biological chemistry.

Development of an adenovirus vector lacking the expression of virus-associated RNAs.

H. Mizuguchi, H. Miyoshi, F. Sakurai, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Efficiency of the elongation factor-1alpha promoter in mammalian embryonic stem cells using lentiviral gene delivery systems.

Sinae Kim, S. Moon, K. Cha, 2007, Stem cells and development.

IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages.

S. Akira, H. Kuwata, T. Kaisho, 2003, Blood.

Identification of genes potentially involved in supporting hematopoietic stem cell activity of stromal cell line MC3T3-G2/PA6

H. Miyoshi, K. Katayama, H. Ichikawa, 2008, International journal of hematology.

Mac-1(low) early myeloid cells in the bone marrow-derived SP fraction migrate into injured skeletal muscle and participate in muscle regeneration.

H. Nakauchi, A. Uezumi, S. Takeda, 2004, Biochemical and biophysical research communications.

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis

M. Mack, M. Colonna, S. Hultgren, 2014, EBioMedicine.

Generation of Corneal Epithelial Cells from Induced Pluripotent Stem Cells Derived from Human Dermal Fibroblast and Corneal Limbal Epithelium

M. Yamato, K. Nishida, R. Hayashi, 2012, PloS one.

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

Hiroyuki Miyoshi, Shizuo Akira, S. Akira, 2013, The EMBO journal.

The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair

Hiroyuki Miyoshi, H. Miyoshi, Thaddeus S Stappenbeck, 2009, Science.

Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis

M. Taketo, M. Matsuda, H. Miyoshi, 2016, PloS one.

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells

K. Obama, H. Miyoshi, Yutaka Y. Yasui, 2021, Communications biology.

CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.

M. Aoki, M. Taketo, H. Miyoshi, 2010, Gastroenterology.

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

Y. Nakagawa, T. He, Y. Naito, 2016, Scientific Reports.

miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro

H. Okano, Mari Nakamura, A. Yoo, 2020, Cells.

Establishment of monoclonal antibodies against a novel eosinophil-specific cell surface molecule, major facilitator super family domain containing 10.

O. Kaminuma, H. Miyoshi, K. Katayama, 2012, Immunology letters.

Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells

Hiroyuki Miyoshi, Kazuto Nakada, J. Hayashi, 2010, FEBS letters.

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Sarah L. Brown, R. Xavier, J. Lennerz, 2008, Nature.

Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.

K. Mizuseki, Y. Sasai, Fumitaka Osakada, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells

Yukio Nakamura, H. Miyoshi, R. Kurita, 2012, PloS one.

Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2

M. Taketo, H. Miyoshi, S. Ito, 2016, Cancer science.

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference

K. Taira, M. Miyagishi, H. Miyoshi, 2004, Oncogene.

Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells.

T. Masuda, M. Kannagi, H. Miyoshi, 2004, Microbes and infection.

Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii

E. Oh, H. Miyoshi, H. Cha, 2017, Molecular Cancer.

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

H. Miyoshi, Naomi M. Sonnek, K. VanDussen, 2017, The EMBO journal.

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

Hiroyuki Miyoshi, H. Miyoshi, Thaddeus S Stappenbeck, 2013, Nature Protocols.

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays

H. Miyoshi, P. Tarr, M. Ciorba, 2014, Gut.

Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine.

H. Seno, M. Taketo, T. Chiba, 2017, Cancer research.

Visualization of spatiotemporal activation of Notch signaling: live monitoring and significance in neural development.

A. Miyawaki, H. Okano, J. Kohyama, 2005, Developmental biology.

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

Hiroyuki Miyoshi, Clara Moon, Thaddeus S. Stappenbeck, 2013, Mucosal Immunology.

Development of a Self-Inactivating Lentivirus Vector

Fred H. Gage, Hiroyuki Miyoshi, Inder M. Verma, 1998, Journal of Virology.

Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle.

Atsushi Miyawaki, Hiroyuki Miyoshi, Michiyuki Matsuda, 2017, Molecular cell.

Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification.

Hideki Uosaki, Chulan Kwon, Kuniaki Saito, 2018, Cell stem cell.

Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue Injury

Terry P Yamaguchi, Hiroyuki Miyoshi, H. Miyoshi, 2012, Science.

Efficient colonic mucosal wound repair requires Trem2 signaling

Sarah L. Brown, Hiroyuki Miyoshi, Hiroshi Seno, 2009, Proceedings of the National Academy of Sciences.

CIN85, a Cbl‐interacting protein, is a component of AMAP1‐mediated breast cancer invasion machinery

Y. Onodera, H. Miyoshi, H. Sabe, 2007, The EMBO journal.

Visualizing developmentally programmed endoreplication in mammals using ubiquitin oscillators

A. Miyawaki, Asako Sakaue-Sawano, Eiki Takahashi, 2013, Development.

Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells

H. Seno, M. Taketo, T. Chiba, 2019, Proceedings of the National Academy of Sciences.

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Hiroyuki Miyoshi, Hiroyuki Mano, Kazuto Nakada, 2015, Scientific Reports.

Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells.

M. Vidal, A. Iwama, H. Miyoshi, 2011, Experimental hematology.

Positive Feedback Loop of OCT4 and c‐JUN Expedites Cancer Stemness in Liver Cancer

C. Chai, Yukio Nakamura, Deng-Chyang Wu, 2016, Stem cells.

Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells

H. Okano, M. Suematsu, H. Miyoshi, 2019, International journal of molecular sciences.

Generation of Induced Pluripotent Stem Cells in Rabbits

Hiroyuki Miyoshi, Arata Honda, H. Miyoshi, 2010, The Journal of Biological Chemistry.

Construction of a high-performance human fetal liver-derived lentiviral cDNA library

T. Oikawa, H. Miyoshi, R. Kurita, 2008, Molecular and Cellular Biochemistry.

miR-342-3p regulates MYC transcriptional activity via direct repression of E2F1 in human lung cancer.

Y. Yatabe, K. Yanagisawa, Takashi Takahashi, 2015, Carcinogenesis.

Intratracheal administration of third-generation lentivirus vector encoding MPT51 from Mycobacterium tuberculosis induces specific CD8+ T-cell responses in the lung.

H. Miyoshi, K. Chida, D. Hashimoto, 2008, Vaccine.

SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner.

Ji-Seon Lee, I. Nakano, Kwang-Hoon Chun, 2015, Neuro-oncology.

Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells

F. Matsuda, K. Higasa, M. Taketo, 2018, Oncotarget.

An improved method for culturing patient-derived colorectal cancer spheroids

M. Taketo, H. Miyoshi, Y. Sakai, 2018, Oncotarget.

Abnormal DNA Methyltransferase Expression in Mouse Germline Stem Cells Results in Spermatogenic Defects1

S. Toyokuni, N. Nakatsuji, S. Takashima, 2009, Biology of reproduction.

Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice.

M Oshima, M. Taketo, H. Miyoshi, 1999, Cancer research.

Hepatocellular carcinoma development induced by conditional β‐catenin activation in Lkb1+/− mice

M. Aoki, M. Taketo, A. Mori, 2009, Cancer science.

Optimization of an siRNA‐expression system with an improved hairpin and its significant suppressive effects in mammalian cells

Hiroyuki Miyoshi, Yutaka Kawakami, Kazunari Taira, 2004, The journal of gene medicine.

Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.

A. Iwama, H. Nakauchi, H. Taniguchi, 2007, Gastroenterology.

Reprogramming Antagonizes the Oncogenicity of HOXA13‐Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells

S. Kishikawa, K. Nagata, C. Chai, 2017, Stem cells.

Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2

Sunday S. Oladipupo, D. Lim, Byung-Soo Kim, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Lentiviral Etv 2 Delivery Into Ischemic Hindlimbs Results in Enhanced Blood Perfusion Recovery Accompanying Augmented Capillary Formation and Reduced Tissue Fibrosis

Sunday S. Oladipupo, D. Lim, Byung-Soo Kim, 2015 .

Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I

D. James, N. Turner, G. Cooney, 2008, Diabetes.

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells

K. Obama, H. Miyoshi, Yutaka Y. Yasui, 2021, Communications Biology.

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

N. Minato, M. Aoki, M. Taketo, 2007, Nature Genetics.

LKB1 Suppresses p21-activated Kinase-1 (PAK1) by Phosphorylation of Thr109 in the p21-binding Domain*

M. Aoki, M. Taketo, H. Miyoshi, 2010, The Journal of Biological Chemistry.

Retroviral Vector Targeting to Human Immunodeficiency Virus Type 1-Infected Cells by Receptor Pseudotyping

I. Verma, H. Miyoshi, N. Somia, 2000, Journal of Virology.

Effective transduction and stable transgene expression in human blood cells by a third-generation lentiviral vector

S. Asano, H. Miyoshi, Y. Soda, 2003, Gene Therapy.

lymphoblastic leukemia positive acute - specific cell death in Philadelphia chromosome A novel maxizyme vector targeting a bcr-abl fusion gene induced

S. Asano, S. Nakazawa, K. Taira, 2013 .

A novel maxizyme vector targeting a bcr-abl fusion gene induced specific cell death in Philadelphia chromosome-positive acute lymphoblastic leukemia.

S. Asano, S. Nakazawa, K. Taira, 2004, Blood.

Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin.

M. Taketo, H. Miyoshi, M. Oshima, 2002, Cancer research.

Autologous transplantation of SM/C-2.6(+) satellite cells transduced with micro-dystrophin CS1 cDNA by lentiviral vector into mdx mice.

A. Uezumi, Hiroshi Yamamoto, S. Takeda, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Autologous Transplantation of SM/C-2.6+ Satellite Cells Transduced with Micro-dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice.

A. Uezumi, Hiroshi Yamamoto, S. Takeda, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Lentiviral vector-mediated transduction of murine CD34(-) hematopoietic stem cells.

H. Nakauchi, H. Miyoshi, H. Ema, 2002, Experimental hematology.

Whole‐Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell‐Derived Neural Stem/Progenitor Cells

H. Okano, J. Kohyama, Y. Toyama, 2017, Stem cells.

Differential Developmental Ability of Embryos Cloned from Tissue‐Specific Stem Cells

H. Miyoshi, N. Ogonuki, A. Ogura, 2007, Stem cells.

Suppression of disease phenotypes of adult mito-mice carrying pathogenic mtDNA by bone marrow transplantation.

J. Hayashi, H. Miyoshi, Kaori Ishikawa, 2006, Human molecular genetics.

Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect.

H. Okano, O. Sampetrean, H. Saya, 2020, Human gene therapy.

IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-α production in macrophages

S. Akira, H. Kuwata, T. Kaisho, 2003 .

CD226 (DNAM-1) Is Involved in Lymphocyte Function–associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation

H. Nakauchi, T. Sumida, H. Miyoshi, 2003, The Journal of experimental medicine.

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development

J. Hayashi, M. Ohira, H. Nagase, 2012, Proceedings of the National Academy of Sciences.

A Specific Region of 37 Amino Acid Residues in the SPRY (B30.2) Domain of African Green Monkey TRIM5α Determines Species-Specific Restriction of Simian Immunodeficiency Virus SIVmac Infection

Y. Nagai, H. Miyoshi, T. Shioda, 2005, Journal of Virology.

Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1.

J. Alam, C. Payá, J. Grande, 2001, Kidney international.

Suppression of Tubulin Polymerization by the LKB1-Microtubule-associated Protein/Microtubule Affinity-regulating Kinase Signaling*

H. Clevers, M. Aoki, M. Taketo, 2007, Journal of Biological Chemistry.

Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice.

M. Seldin, M. Taketo, M. Imamura, 2002, Cancer research.

Pathogenic mitochondrial DNA‐induced respiration defects in hematopoietic cells result in anemia by suppressing erythroid differentiation

J. Hayashi, H. Miyoshi, K. Nakada, 2007, FEBS letters.

Lentiviral vector-mediated SERCA2 gene transfer protects against heart failure and left ventricular remodeling after myocardial infarction in rats.

Y. Ikeda, N. Koitabashi, M. Kurabayashi, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Gene delivery to hematopoietic stem cells using lentiviral vectors.

H. Miyoshi, 2004, Methods in molecular biology.

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

H. Ikeuchi, S. Hirota, S. Miyano, 2019, Nature.

Autophagy Creates a CTL Epitope That Mimics Tumor-Associated Antigens

H. Miyoshi, T. Yoshimori, K. Kuzushima, 2012, PloS one.

A Targeted Mutation of Nkd1 Impairs Mouse Spermatogenesis*

M. Taketo, H. Miyoshi, T. Ishikawa, 2005, Journal of Biological Chemistry.

Diffuse-Type Gastric Carcinoma: Progression, Angiogenesis, and Transforming Growth Factor β Signaling

H. Aburatani, Hiroshi I. Suzuki, K. Miyazono, 2009 .

Wnt-expressing cells in the intestines: guides for tissue remodeling

H. Miyoshi, 2017, Journal of biochemistry.

Counteracting stem cell expansion during wound repair

H. Miyoshi, T. Stappenbeck, 2013, Cell cycle.

A unique role for autophagy and Atg 16 L 1 in Paneth cells in murine and human intestine

Thaddeus, Elizabeth, Sarah L. Brown, 2009 .

Type I interferons link viral infection to enhanced epithelial turnover and repair.

H. Piwnica-Worms, D. Lenschow, H. Virgin, 2015, Cell host & microbe.

A Chemosensitivity Study of Colorectal Cancer Using Xenografts of Patient-Derived Tumor-Initiating Cells

M. Taketo, H. Miyoshi, Y. Sakai, 2018, Molecular Cancer Therapeutics.

A Novel Strategy to Increase the Proliferative Potential of Adult Human β-Cells While Maintaining Their Differentiated Phenotype

M. Mcdaniel, H. Miyoshi, N. Rohatgi, 2013, PloS one.

Title FANCI-FANCD 2 stabilizes the RAD 51-DNA complex bybinding RAD 51 and protects the 5 ′-DNA end

H. Kurumizaka, Koichi Sato, H. Miyoshi, 2018 .

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

H. Kurumizaka, Koichi Sato, H. Miyoshi, 2016, Nucleic acids research.

DNMT3A R882 mutants interact with polycomb proteins to block haematopoietic stem and leukaemic cell differentiation

K. Shirahige, M. Kurokawa, H. Miyoshi, 2016, Nature Communications.

An Oncogenic Protein Golgi Phosphoprotein 3 Up-regulates Cell Migration via Sialylation*

J. Gu, T. Isaji, W. Gu, 2014, The Journal of Biological Chemistry.

Arid1a is essential for intestinal stem cells through Sox9 regulation

H. Seno, M. Taketo, T. Chiba, 2019, Proceedings of the National Academy of Sciences.

Genes to Cells

M. Taketo, M. Okabe, H. Miyoshi, 2018 .

CD 226 ( DNAM-1 ) Is Involved in Lymphocyte Function – associated Antigen 1 Costimulatory Signal for Naive T Cell Differentiation and Proliferation

H. Nakauchi, T. Sumida, H. Miyoshi, 2003 .

T-box 21 transcription factor is responsible for distorted T(H)2 differentiation in human peripheral CD4+ T cells.

O. Kaminuma, A. Mori, H. Miyoshi, 2009, The Journal of allergy and clinical immunology.

Lentiviral gp34/OX40L Gene Transfer into Dendritic Cells Facilitates Alloreactive CD4+ T-Cell Response In Vitro

H. Miyoshi, A. Takaori-Kondo, Masayuki Kobayashi, 2004, International journal of hematology.

Differential developmental ability of embryos cloned from tissue-specific stem cells.

H. Miyoshi, N. Ogonuki, A. Ogura, 2007, Stem cells.

Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body

I. Tooyama, E. Sasaki, H. Miyoshi, 2016, Scientific Reports.

Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†

H. Tanabe, A. Kawauchi, H. Miyoshi, 2019, Biology of Reproduction.

Inefficient reprogramming of the hematopoietic stem cell genome following nuclear transfer

F. Aoki, H. Miyoshi, N. Ogonuki, 2006, Journal of Cell Science.

Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

M. Taketo, H. Miyoshi, Y. Sakai, 2020, Cancers.

Direct evidence for ex vivo expansion of human hematopoietic stem cells.

H. Miyoshi, K. Ando, T. Yahata, 2005, Blood.

Noninvasive and real-time assessment of reconstructed functional human endometrium in NOD/SCID/γcnull immunodeficient mice

H. Okano, T. Nomura, Mamoru Ito, 2007, Proceedings of the National Academy of Sciences.

103. PGK and CMV Promoters Exert the Strongest Activity in Lentiviral Gene Transduction of Myeloid Cells Including Mature Neutrophils

S. Ohga, S. Asano, H. Miyoshi, 2005 .

Visualization of spatiotemporal dynamics of human glioma stem cell invasion

H. Okano, O. Sampetrean, H. Saya, 2019, Molecular Brain.

Ubiquitylation and Degradation of Serum-inducible Kinase by hVPS18, a RING-H2 Type Ubiquitin Ligase*

K. Nakayama, H. Miyoshi, S. Hatakeyama, 2005, Journal of Biological Chemistry.

In vivo imaging of engrafted neural stem cells: its application in evaluating the optimal timing of transplantation for spinal cord injury

C. Contag, Y. Toyama, Y. Iwamoto, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell‐Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury

H. Okano, J. Kohyama, H. Miyoshi, 2018, Stem cells translational medicine.

MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer

S. Tsunoda, K. Obama, T. Nishigori, 2019, Cancers.

Corrigendum: Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

M. Soda, H. Mano, J. Hayashi, 2015, Scientific Reports.

Transplantation of human neural stem/progenitor cells overexpressing galectin-1 improves functional recovery from focal brain ischemia in the mongolian gerbil

H. Okano, K. Sawamoto, Y. Toyama, 2011, Molecular Brain.

EpCAM (CD326) Regulates Intestinal Epithelial Integrity and Stem Cells via Rho-Associated Kinase

H. Miyoshi, M. Udey, L. Dow, 2021, Cells.

Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas

M. Taketo, H. Miyoshi, M. Oshima, 2004, British Journal of Cancer.

Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii

E. Oh, H. Miyoshi, H. Cha, 2017, Molecular Cancer.

Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/−p53−/− compound mutant mice

M. Taketo, H. Miyoshi, M. Oshima, 2006, Oncogene.

Novel and efficient method for culturing patient‐derived gastric cancer stem cells

K. Obama, M. Taketo, H. Miyoshi, 2023, Cancer science.

Visualization of spatiotemporal dynamics of human glioma stem cell invasion

H. Okano, O. Sampetrean, H. Saya, 2019, Molecular Brain.

Peroxisome Proliferator-activated Receptor -mediated Regulation of Neural Stem Cell Proliferation

T. Mayumi, Y. Terauchi, T. Kadowaki, 2006 .

Hematopoietic stem cell aging is associated with functional decline and delayed cell cycle progression.

H. Miyoshi, H. Ichikawa, Shinichi Noda, 2009, Biochemical and biophysical research communications.