S. Rangappa

发表

A Green Synthesis of 1,5-Benzodiazepines using Reusable-Heterogeneous Silica Sulfuric Acid Catalyst under Solvent-Free Conditions and their Antileukemic Activity

K. B. Harsha, C. Kavitha, T. R. Swaroop, 2021 .

Screening of quinoline, 1,3-benzoxazine, and 1,3-oxazine-based small molecules against isolated methionyl-tRNA synthetase and A549 and HCT116 cancer cells including an in silico binding mode analysis.

Basappa, Julian E. Fuchs, A. Bender, 2015, Organic & biomolecular chemistry.

Novel Synthetic Biscoumarins Target Tumor Necrosis Factor-α in Hepatocellular Carcinoma in Vitro and in Vivo*

Basappa, Julian E. Fuchs, A. Bender, 2014, The Journal of Biological Chemistry.

Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo*

Basappa, Julian E. Fuchs, A. Bender, 2014, The Journal of Biological Chemistry.

Elicitation of resistance and associated defense responses in Trichoderma hamatum induced protection against pearl millet downy mildew pathogen

S. Rangappa, R. Srivastava, C. Siddaiah, 2017, Scientific Reports.

Regioselective competitive synthesis of 3,5-bis(het) aryl pyrrole-2-carboxylates/carbonitriles vs. β-enaminones from β-thioxoketones

S. Rangappa, K. Rangappa, S. Raghavan, 2021, Tetrahedron Letters.

Exploring the newer oxadiazoles as real inhibitors of human SIRT2 in hepatocellular cancer cells.

Basappa, S. Rangappa, K. Rangappa, 2020, Bioorganic & medicinal chemistry letters.

Sulfated Ceria Catalyzed Synthesis of Imidazopyridines and Their Implementation as DNA Minor Groove Binders

Basappa, Julian E. Fuchs, A. Bender, 2019, Chemistry & biodiversity.

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway

Basappa, G. Sethi, A. Bhattacharjee, 2018, Front. Pharmacol..

An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway.

S. Rangappa, K. Rangappa, A. Kumar, 2016, International journal of oncology.

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Basappa, G. Sethi, S. Rangappa, 2016, PloS one.

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

Lewis H. Mervin, Basappa, A. Bender, 2016, PloS one.

Novel Adamantanyl-Based Thiadiazolyl Pyrazoles Targeting EGFR in Triple-Negative Breast Cancer

Lewis H. Mervin, Basappa, Julian E. Fuchs, 2016, ACS omega.

Nano-cuprous oxide catalyzed one-pot synthesis of a carbazole-based STAT3 inhibitor: a facile approach via intramolecular C–N bond formation reactions

Basappa, Julian E. Fuchs, A. Bender, 2016 .

Synthesis of 1,2-benzisoxazole tethered 1,2,3-triazoles that exhibit anticancer activity in acute myeloid leukemia cell lines by inhibiting histone deacetylases, and inducing p21 and tubulin acetylation.

Basappa, Julian E. Fuchs, A. Bender, 2015, Bioorganic & medicinal chemistry.

Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells.

Basappa, Julian E. Fuchs, A. Bender, 2015, Bioorganic & medicinal chemistry letters.

A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2

Basappa, Julian E. Fuchs, A. Bender, 2015, PloS one.

Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2.

Chandra, Basappa, Julian E. Fuchs, 2015, Bioorganic & medicinal chemistry letters.

Development of Novel Triazolo-Thiadiazoles from Heterogeneous “Green” Catalysis as Protein Tyrosine Phosphatase 1B Inhibitors

Basappa, Julian E. Fuchs, A. Bender, 2015, Scientific Reports.

Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells

K. Ahn, S. Rangappa, A. Chinnathambi, 2022, Molecules.

Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds

Basappa, V. Gupta, S. Rangappa, 2019, iScience.

An Easy and Efficient Method for the Synthesis of Quinoxalines Using Recyclable and Heterogeneous Nanomagnetic‐Supported Acid Catalyst under Solvent‐Free Condition

K. B. Harsha, T. R. Swaroop, S. Rangappa, 2018 .

Correction: Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Basappa, G. Sethi, S. Rangappa, 2017, PloS one.

Crocetin imparts antiproliferative activity via inhibiting STAT3 signaling in hepatocellular carcinoma

K. Ahn, Chulwon Kim, S. Rangappa, 2021, IUBMB life.

3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular Carcinoma

G. Sethi, K. Ahn, S. Rangappa, 2021, Biology.

Brucein D modulates MAPK signaling cascade to exert multi-faceted anti-neoplastic actions against breast cancer cells.

K. Ahn, S. Rangappa, K. Rangappa, 2021, Biochimie.

Vitexin abrogates invasion and survival of hepatocellular carcinoma cells through targeting STAT3 signaling pathway.

G. Sethi, K. Ahn, Jong Hyun Lee, 2020, Biochimie.

Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer

Basappa, Vikas H. Malojirao, S. Rangappa, 2020, Biomedicines.

Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma

G. Sethi, K. Ahn, Jong Hyun Lee, 2019, Biomolecules.

Leelamine Exerts Antineoplastic Effects in Association with Modulating Mitogen‑Activated Protein Kinase Signaling Cascade

K. Ahn, S. Rangappa, K. Rangappa, 2022, Nutrition and cancer.

MOLPRINT 2D-based identification and synthesis of novel chromene based small molecules that target PLA2: validation through chemo- and bioinformatics approaches

Lewis H. Mervin, Basappa, Julian E. Fuchs, 2015 .

Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase

S. Rangappa, P. Lobie, V. Pandey, 2022, Molecules.

Tris DBA Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Affecting Multiple Oncogenic Proteins

G. Sethi, K. Ahn, Chulwon Kim, 2020 .

Pyrrolidine-based cationic γ-peptide: a DNA-binding molecule works as a potent anti-gene agent

S. Rangappa, K. Rangappa, M. Umashankara, 2022, Medicinal Chemistry Research.

Anti-proliferative activity and characterization data on oxadiazole derivatives

Basappa, S. Rangappa, K. Rangappa, 2020, Data in brief.

New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis

S. Rangappa, K. Rangappa, C. D. Mohan, 2021, Cancers.

The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells

G. Sethi, K. Ahn, Jong Hyun Lee, 2020 .

Synthesis of CC, CN coupled novel substituted dibutyl benzothiazepinone derivatives and evaluation of their thrombin inhibitory activity.

Basappa, A. Bender, Leen Kalash, 2019, Bioorganic chemistry.

The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells

G. Sethi, K. Ahn, Jong Hyun Lee, 2019, Biomolecules.

Small molecule based five-membered heterocycles: A view of liquid crystalline properties beyond the biological applications

S. Rangappa, K. Rangappa, C. D. Mohan, 2020, Journal of Molecular Liquids.

Innovative approach for the synthesis of N-substituted amides from nitriles and alcohols using propylphosphonic anhydride (T3P®) under solvent-free conditions

S. Rangappa, K. Rangappa, K. Mantelingu, 2019, Synthetic Communications.

Efficient One‐Pot Synthesis of 3,5‐Disubstituted 1,3,4‐Thiadiazole from Dithioesters under Mild Condition

S. Rangappa, K. Rangappa, K. Mantelingu, 2019, ChemistrySelect.

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

Basappa, Julian E. Fuchs, A. Bender, 2017, BMC Cancer.

Cyclization of Activated Methylene Isocyanides with Methyl N(N),N′-Di(tri)substituted Carbamimidothioate: A Novel Entry for the Synthesis of N,1-Aryl-4-tosyl/ethoxycarbonyl-1H-imidazol-5-amines

T. R. Swaroop, S. Rangappa, K. Rangappa, 2019, SynOpen.

Identification of β‐aminopyrrolidine containing peptides as β‐amyloid aggregation inhibitors for Alzheimer's disease

S. Rangappa, K. Rangappa, Umashankar Muddegowda, 2022, Journal of peptide science : an official publication of the European Peptide Society.

A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression

S. Rangappa, K. Rangappa, Kothanahally S Sharath Kumar, 2018, Molecular and Cellular Biochemistry.

Synthesis, characterization and cytotoxicity studies of 1,2,3-triazoles and 1,2,4-triazolo [1,5-a] pyrimidines in human breast cancer cells.

Basappa, K. B. Harsha, S. Rangappa, 2018, Bioorganic & medicinal chemistry letters.

Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies.

M. Ashrafizadeh, S. Rangappa, K. Rangappa, 2021, Bioorganic chemistry.

Structural studies of 2,5-disubstituted 1,3,4-thiadiazole derivatives from dithioesters under the mild condition: Studies on antioxidant, antimicrobial activities, and molecular docking

S. Rangappa, Hassan A. Swarup, Sandhya C. Nagarakere, 2020 .

A Nano-MgO and Ionic Liquid-Catalyzed ‘Green’ Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51)

Lewis H. Mervin, Chandra, Basappa, 2015, PloS one.

Endophytic Fungi—Alternative Sources of Cytotoxic Compounds: A Review

V. Gupta, S. Rangappa, A. Hashem, 2018, Front. Pharmacol..

Six-substituted benzothiazole based dispersed azo dyes having antipyrine moiety: synthesis, characterization, DFT, antimicrobial, anticancer and molecular docking studies

S. Rangappa, J. Keshavayya, M. R. Maliyappa, 2022, Journal of the Iranian Chemical Society.

Synthesis, Characterization and Biological Potency of Butyl‐Pyridone Based Azo Dyes

Vinod Kumar, S. Rangappa, J. Keshavayya, 2020 .

Bacteria as a treasure house of secondary metabolites with anticancer potential.

G. Sethi, S. Rangappa, K. Rangappa, 2021, Seminars in cancer biology.

Tris(dibenzylideneacetone)dipalladium(0) (Tris DBA) Abrogates Tumor Progression in Hepatocellular Carcinoma and Multiple Myeloma Preclinical Models by Regulating the STAT3 Signaling Pathway

G. Sethi, K. Ahn, A. Kunnumakkara, 2021, Cancers.

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs.

Basappa, Julian E. Fuchs, A. Bender, 2016, Bioorganic & medicinal chemistry letters.

Biofabrication of Zinc Oxide Nanoparticles With Syzygium aromaticum Flower Buds Extract and Finding Its Novel Application in Controlling the Growth and Mycotoxins of Fusarium graminearum

V. Gupta, B. Prasad, S. Rangappa, 2019, Front. Microbiol..

In vitro, in vivo and in silico-driven identification of novel benzimidazole derivatives as anticancer and anti-inflammatory agents

S. Rangappa, B. Poojary, V. K. Merugumolu, 2021, Journal of the Iranian Chemical Society.

Inhibitory effect of C. zeylanicum, C. longa, O. basilicum, Z. officinale, and C. martini essential oils on growth and ochratoxin A content of A. ochraceous and P. verrucosum in maize grains

R. Prasad, S. Rangappa, K. Kadirvelu, 2020, Biotechnology reports.

Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature.

V. Gupta, G. Sethi, S. Rangappa, 2020, Seminars in cancer biology.

Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma.

G. Sethi, S. Rangappa, K. Rangappa, 2021, Biochimica et biophysica acta. Reviews on cancer.

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells

Basappa, G. Sethi, A. Bhattacharjee, 2018, Front. Oncol..

Orientational order parameter of liquid crystalline mixtures - A birefringence study

S. Rangappa, Shahina, C. M. Subhan, 2018, Nanosystems: Physics, Chemistry, Mathematics.

Orientational order parameter of some CBOnO.m liquid crystalline compounds—an optical study

S. Agarwal, S. Rangappa, C. M. Subhan, 2016 .

Novel 1,2,5-Trisubstituted Benzimidazoles Potentiate Apoptosis by Mitochondrial Dysfunction in Panel of Cancer Cells

S. Rangappa, Akshay Uttarkar, V. Niranjan, 2022, ACS omega.

Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer

N. Merchant, V. Jala, S. Rangappa, 2018, Molecular Cancer Therapeutics.

Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation

Basappa, Julian E. Fuchs, A. Bender, 2018, Proceedings of the National Academy of Sciences.

Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma

G. Sethi, K. Ahn, Jong Hyun Lee, 2020, Journal of advanced research.

Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ

Basappa, Julian E. Fuchs, K. R. Dinesh, 2014 .

Pyrimidine-2,4-dione Targets STAT3 Signaling Pathway to Induce Cytotoxicity in Hepatocellular Carcinoma Cells.

S. Rangappa, K. Rangappa, A. Chinnathambi, 2021, Bioorganic & medicinal chemistry letters.

Identification of a novel 1,2 oxazine that can induce apoptosis by targeting NF-κB in hepatocellular carcinoma cells

Basappa, Sachin P. Ambekar, S. Rangappa, 2020, Biotechnology reports.

Brucein D imparts a growth inhibitory effect in multiple myeloma cells by abrogating the Akt‐driven signaling pathway

K. Ahn, J. Um, S. Rangappa, 2022, IUBMB life.

Effects of the multiple O-glycosylation states on antibody recognition of the immunodominant motif in MUC1 extracellular tandem repeats

S. Nishimura, S. Rangappa, H. Hinou, 2016 .

Triazole‐Pyridine Dicarbonitrile Targets Phosphodiesterase 4 to Induce Cytotoxicity in Lung Carcinoma Cells

Basappa, A. Bender, S. Rangappa, 2019, Chemistry & biodiversity.

Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

G. Sethi, M. Ashrafizadeh, S. Rangappa, 2023, Medicinal research reviews.

Glycoside cluster effects on antibody recognition of MUC1 glycopeptides

S. Rangappa, 2016 .

Six-substituted benzothiazole based dispersed azo dyes having antipyrine moiety: synthesis, characterization, DFT, antimicrobial, anticancer and molecular docking studies

S. Rangappa, J. Keshavayya, M. R. Maliyappa, 2022, Journal of the Iranian Chemical Society.

Genetic and chemotypic diversity of two lineages of Aspergillus flavus isolated from maize seeds of different agroclimatic niches of India

S. Rangappa, C. D. Mohan, Narasimhamurthy Konappa, 2020, Indian Phytopathology.

Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

Basappa, Julian E. Fuchs, A. Bender, 2017, BMC Cancer.

Coumarin derivative as a potent drug candidate against triple negative breast cancer targeting the frizzled receptor of wingless-related integration site signaling pathway

S. Rangappa, R. Kusanur, Akshay Uttarkar, 2022, Journal of biomolecular structure & dynamics.

A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression

S. Rangappa, K. Rangappa, H. Ananda, 2018, Molecular and Cellular Biochemistry.

Healthy human serum N-glycan profiling reveals the influence of ethnic variation on the identified cancer-relevant glycan biomarkers

S. Nishimura, S. Rangappa, T. Kamiyama, 2018, PloS one.

Metabolite Profiling of Alangium salviifolium Bark Using Advanced LC/MS and GC/Q-TOFTechnology

V. Gupta, Minaxi Sharma, S. Rangappa, 2020, Cells.

Design, synthesis and docking studies of novel 4-aminophenol-1,2,4-oxadiazole hybrids as apoptosis inducers against triple negative breast cancer cells targeting MAP kinase

H. K. Vivek, S. Rangappa, M. Sennappan, 2023, Journal of biomolecular structure & dynamics.

Synthesis of Coumarin-benzotriazole Hybrids and Evaluation of their Anti-tubercular Activity

Basappa, Sachin P. Ambekar, S. Rangappa, 2017 .

Adamantyl-tethered-biphenylic compounds induce apoptosis in cancer cells by targeting Bcl homologs.

Basappa, Julian E. Fuchs, A. Bender, 2016, Bioorganic & medicinal chemistry letters.

Journey of A Drug from Table to Trade

S. Rangappa, 2018, Novel Approaches in Drug Designing & Development.

Ag mediated plasmonic AgO/ZnO composite and its pharmaceutical relevance

S. Rangappa, K. Rangappa, S. Shivanna, 2023, Materials Science and Engineering: B.

Microwave assisted one-pot access to pyrazolo quinolinone and tetrahydroisoxazolo quinolinone derivatives via T3P®-DMSO catalysed tandem oxidative–condensation reaction

K. B. Harsha, S. Rangappa, K. Rangappa, 2023, RSC advances.

Design and synthesis of 4-aminophenol-1,3,4-oxadiazole derivative potentiates apoptosis by targeting MAP kinase in triple negative breast cancer cells.

S. Rangappa, M. Sennappan, B. Anil Kumar, 2023, Journal of biomolecular structure & dynamics.

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

Basappa, G. Sethi, S. Rangappa, 2016, PloS one.

Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ

Basappa, Julian E. Fuchs, K. R. Dinesh, 2014 .

An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway.

S. Rangappa, K. Rangappa, A. Kumar, 2016, International journal of oncology.

Sulfur (SⅥ)-containing heterocyclic hybrids as antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and its SAR.

S. Rangappa, K. Rangappa, R. Verma, 2024, Bioorganic chemistry.

Novel quinoline-4-carboxamide derivatives potentiates apoptosis by targeting PDK1 to overcome chemo-resistance in colorectal cancer: Theoretical and experimental results

B. S. Chethan, K. B. Harsha, S. Rangappa, 2024, Heliyon.