J. Thundathil

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The effects of increased testicular temperature on testis-specific isoform of Na+/K+ -ATPase in sperm and its role in spermatogenesis and sperm function.

J. Kastelic, J. Thundathil, G. D. Rajamanickam, 2012, Reproduction in domestic animals = Zuchthygiene.

Hyperthermia is more important than hypoxia as a cause of disrupted spermatogenesis and abnormal sperm.

J. Kastelic, J. Thundathil, G. Rizzoto, 2019, Theriogenology.

Hyperthermia and not hypoxia may reduce sperm motility and morphology following testicular hyperthermia

J. Kastelic, J. Thundathil, G. Rizzoto, 2017 .

Content and activity of the testis-specific isoform of angiotensin-converting enzyme are reduced in frozen-thawed bull spermatozoa.

J. Kastelic, J. Thundathil, G. Rizzoto, 2018, Reproduction, fertility, and development.

Intracytoplasmic Sperm Injection in Cattle

J. Kastelic, J. Thundathil, Veena Unnikrishnan, 2021, Genes.

Testis‐specific isoform of Na/K‐ATPase (ATP1A4) regulates sperm function and fertility in dairy bulls through potential mechanisms involving reactive oxygen species, calcium and actin polymerization

J. Kastelic, J. Thundathil, G. D. Rajamanickam, 2017, Andrology.

Melatonin or L-arginine in semen extender mitigate reductions in quality of frozen-thawed sperm from heat-stressed rams.

J. Kastelic, J. Thundathil, A. Shahat, 2022, Animal reproduction science.

Fertility management of bulls to improve beef cattle productivity.

J. Kastelic, J. Thundathil, A. Dance, 2016, Theriogenology.

Elevated testicular temperature modulates expression patterns of sperm proteins in Holstein bulls

J. Kastelic, J. Thundathil, L. D. Newton, 2009, Molecular reproduction and development.

Fertilization characteristics and in vitro embryo production with bovine sperm containing multiple nuclear vacuoles

J. Thundathil, R. Mapletoft, A. Barth, 1998, Molecular reproduction and development.

An investigation of the fertilizing characteristics of pyriform-shaped bovine spermatozoa.

J. Thundathil, R. Mapletoft, A. Barth, 1999, Animal reproduction science.

Effect of the knobbed acrosome defect in bovine sperm on IVF and embryo production.

J. Thundathil, R. Mapletoft, A. Barth, 2000, Theriogenology.

Fertilizing characteristics of bovine sperm with flattened or indented acrosomes.

J. Thundathil, C. Barros, R. Mapletoft, 2001, Animal reproduction science.

The use of in vitro fertilization techniques to investigate the fertilizing ability of bovine sperm with proximal cytoplasmic droplets.

J. Thundathil, R. Mapletoft, A. Barth, 2001, Animal reproduction science.

Role of the Na+/K+-ATPase ion pump in male reproduction and embryo development.

J. Kastelic, J. Thundathil, D. R. Câmara, 2017, Reproduction, fertility, and development.

Content of testis-specific isoform of Na/K-ATPase (ATP1A4) is increased during bovine sperm capacitation through translation in mitochondrial ribosomes

J. Kastelic, J. Thundathil, G. D. Rajamanickam, 2017, Cell and Tissue Research.

Bull BSE and semen analysis for predicting bull fertility

J. Kastelic, J. Thundathil, 2012 .

Acute mild heat stress alters gene expression in testes and reduces sperm quality in mice.

J. Kastelic, J. Thundathil, C. Klein, 2020, Theriogenology.

Calorie Restriction Modulates Reproductive Development and Energy Balance in Pre-Pubertal Male Rats

J. Kastelic, J. Thundathil, P. Chelikani, 2019, Nutrients.

Prepubertal nutritional modulation in the bull and its impact on sperm DNA methylation

L. Jouneau, J. Kastelic, J. Thundathil, 2022, Cell and Tissue Research.

A combination of insulin-like growth factor I (IGF-I) and FSH promotes proliferation of prepubertal bovine Sertoli cells isolated and cultured in vitro.

J. Kastelic, J. Thundathil, A. Dance, 2017, Reproduction, fertility, and development.

Na+/K+ATPase as a Signaling Molecule During Bovine Sperm Capacitation1

J. Thundathil, M. Buhr, M. Anzar, 2006, Biology of reproduction.

Impacts of residual feed intake and pre-natal diet on reproductive potential of bulls

J. Kastelic, J. Thundathil, M. Colazo, 2019, Animal Production Science.

Na/K‐ATPase regulates bovine sperm capacitation through raft‐ and non‐raft‐mediated signaling mechanisms

J. Kastelic, J. Thundathil, G. Rajamanickam, 2017, Molecular reproduction and development.

Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism

J. Thundathil, Y. Ou, R. Oko, 2010, BMC Developmental Biology.

The ubiquitous isoform of Na/K-ATPase (ATP1A1) regulates junctional proteins, connexin 43 and claudin 11 via Src-EGFR-ERK1/2-CREB pathway in rat Sertoli Cells†

J. Kastelic, J. Thundathil, G. Rajamanickam, 2017, Biology of Reproduction.

KLC3 is involved in sperm tail midpiece formation and sperm function.

J. Thundathil, Y. Ou, Ying Zhang, 2012, Developmental biology.

Testis-Specific Isoform of Na+-K+ ATPase and Regulation of Bull Fertility

J. Kastelic, J. Thundathil, M. Ojaghi, 2022, International journal of molecular sciences.

Na+/K+ATPase regulates sperm capacitation through a mechanism involving kinases and redistribution of its testis‐specific isoform

J. Kastelic, J. Thundathil, L. D. Newton, 2010, Molecular reproduction and development.

Impact of prenatal maternal nutrition and parental residual feed intake (RFI) on mRNA abundance of metabolic drivers of growth and development in young Angus bulls

D. Wishart, J. Kastelic, J. Thundathil, 2021 .

The effect of volume of culture medium and embryo density on in vitro development of bovine embryos

J. Thundathil, A. Palasz, 1998 .

Testis‐specific isoform of angiotensin‐converting enzyme (tACE) is involved in the regulation of bovine sperm capacitation

J. Kastelic, J. Thundathil, M. Ojaghi, 2017, Molecular reproduction and development.

Moribund sperm in frozen-thawed semen, and sperm motion end points post-thaw and post-swim-up, are related to fertility in Holstein AI bulls.

J. Kastelic, J. Thundathil, H. Shojaei, 2012, Theriogenology.

Testis-specific changes in gene expression of post-pubertal beef bulls divergent for residual feed intake and exposure to different pre-natal diets

J. Kastelic, J. Thundathil, I. Kovalchuk, 2020 .

Melengestrol acetate, estradiol-17β and GnRH for synchronization of estrus and ovulation in beef cows

J. Kastelic, J. Thundathil, R. Mapletoft, 1999 .

The effect of estradiol cypionate (ECP) on ovarian follicular development and ovulation in dairy cattle.

J. Kastelic, J. Thundathil, R. Mapletoft, 1998, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

Premature capacitation and fertility of frozen-thawed bull semen used in artificial insemination☆

H. Rodríguez-Martínez, J. Thundathil, J. Gil, 1999 .

Associations between sperm abnormalities, breed, age, and scrotal circumference in beef bulls.

H. Barkema, J. Kastelic, J. Thundathil, 2011, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

Sperm characteristics in plains (Bison bison bison) versus wood (Bison bison athabascae) bison.

J. Thundathil, B. Elkin, D. Whiteside, 2011, Theriogenology.

Characterization of the Testis-Specific Angiotensin Converting Enzyme (tACE)-Interactome during Bovine Sperm Capacitation

J. Kastelic, J. Thundathil, M. Ojaghi, 2022, Current issues in molecular biology.

The effect of macromolecular supplementation on the surface tension of TCM-199 and the utilization of growth factors by bovine oocytes and embryos in culture.

J. Thundathil, R. Verrall, R. Mapletoft, 2000, Animal reproduction science.

Effect of reduced concentrations of glycerol and various macromolecules on the cryopreservation of mouse and cattle embryos.

J. Thundathil, R. Mapletoft, A. Palasz, 2000, Cryobiology.

Testis-specific isoform of angiotensin-converting enzyme (tACE) as a candidate marker for bull fertility.

J. Kastelic, J. Thundathil, M. Ojaghi, 2018, Reproduction, fertility, and development.

Effect of chilling duration on post-thaw characteristics of sperm from the North American bison (Bison bison).

J. Thundathil, B. Elkin, D. Whiteside, 2013, Reproduction in domestic animals = Zuchthygiene.

Characterization and activity of angiotensin-converting enzyme in Holstein semen.

J. Thundathil, D. S. Costa, 2012, Animal reproduction science.

Nitric Oxide Regulates the Phosphorylation of the Threonine-Glutamine-Tyrosine Motif in Proteins of Human Spermatozoa During Capacitation1

J. Thundathil, C. Gagnon, E. de Lamirande, 2003, Biology of reproduction.

Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents.

J. Thundathil, C. Gagnon, E. de Lamirande, 2002, Molecular human reproduction.

Enhanced early-life nutrition upregulates cholesterol biosynthetic gene expression and Sertoli cell maturation in testes of pre-pubertal Holstein bulls

J. Kastelic, J. Thundathil, I. Kovalchuk, 2019, Scientific Reports.

Breeding soundness evaluation and semen analysis for predicting bull fertility.

J. Kastelic, J. Thundathil, 2008, Reproduction in domestic animals = Zuchthygiene.

Effect of reproductive seasonality on gamete quality in the North American bison (Bison bison bison).

J. Thundathil, B. Elkin, D. Whiteside, 2015, Reproduction in domestic animals = Zuchthygiene.

Enhanced pre-pubertal nutrition upregulates mitochondrial function in testes and sperm of post-pubertal Holstein bulls

J. Kastelic, J. Thundathil, I. Kovalchuk, 2020, Scientific Reports.

Proteins associated with critical sperm functions and sperm head shape are differentially expressed in morphologically abnormal bovine sperm induced by scrotal insulation.

J. Kastelic, J. Thundathil, A. Dance, 2013, Journal of proteomics.

Validating the assessment of bull sperm morphology by veterinary practitioners.

H. Barkema, J. Kastelic, J. Thundathil, 2011, The Canadian veterinary journal = La revue veterinaire canadienne.

Plasma membrane and acrosomal integrity in bovine spermatozoa with the knobbed acrosome defect.

J. Thundathil, R. Mapletoft, A. Barth, 2002, Theriogenology.

Na/K-ATPase and Regulation of Sperm Function

J. Kastelic, J. Thundathil, G. Rajamanickam, 2018, Animal reproduction.

Testicular function and fertility in bulls

J. Kastelic, J. Thundathil, 2019, Bioscientifica Proceedings.

Recovery and cryopreservation of epididymal sperm of plains bison (Bison bison bison) as a model for salvaging the genetics of wood bison (Bison bison athabascae).

J. Thundathil, B. Elkin, D. Whiteside, 2009, Reproduction in domestic animals = Zuchthygiene.

Enhanced early-life nutrition of Holstein bulls increases sperm production potential without decreasing postpubertal semen quality.

J. Kastelic, J. Thundathil, P. Blondin, 2016, Theriogenology.

Review: Testicular vascular cone development and its association with scrotal thermoregulation, semen quality and sperm production in bulls.

J. Kastelic, J. Thundathil, G. Rizzoto, 2018, Animal : an international journal of animal bioscience.

Scrotal subcutaneous temperature is increased by scrotal insulation or whole-body heating, but not by scrotal neck insulation; however, all three heat-stress models decrease sperm quality in bulls and rams.

J. Kastelic, J. Thundathil, A. Shahat, 2021, Journal of thermal biology.

Testicular hyperthermia reduces testosterone concentrations and alters gene expression in testes of Nelore bulls.

J. Kastelic, J. Thundathil, G. Rizzoto, 2020, Theriogenology.

Short-term testicular warming under anesthesia causes similar increases in testicular blood flow in Bos taurus versus Bos indicus bulls, but no apparent hypoxia.

J. Kastelic, J. Thundathil, G. Rizzoto, 2020, Theriogenology.

Arterial blood flow is the main source of testicular heat in bulls and higher ambient temperatures significantly increase testicular blood flow.

J. Kastelic, J. Thundathil, G. Rizzoto, 2018, Theriogenology.

Enhanced early-life nutrition promotes hormone production and reproductive development in Holstein bulls.

J. Kastelic, J. Thundathil, P. Blondin, 2015, Journal of dairy science.

Increased testicular blood flow maintains oxygen delivery and avoids testicular hypoxia in response to reduced oxygen content in inspired air

J. Tyberg, J. Kastelic, J. Thundathil, 2018, Scientific Reports.

Molecular control of mitochondrial function in preimplantation mouse embryos

J. Thundathil, F. Filion, L. Smith, 2005, Molecular reproduction and development.

Preliminary assessment of reproductive technologies in wood bison (Bison bison athabascae): implications for preserving genetic diversity.

J. Thundathil, B. Elkin, J. Nishi, 2007, Theriogenology.

Ouabain-induced activation of phospholipase C zeta and its contributions to bovine sperm capacitation

J. Kastelic, J. Thundathil, Veena Unnikrishnan, 2021, Cell and Tissue Research.

Role of the mitochondrial genome in preimplantation development and assisted reproductive technologies.

J. Thundathil, F. Filion, L. Smith, 2005, Reproduction, fertility, and development.

Relationship between the proportion of capacitated spermatozoa present in frozen-thawed bull semen and fertility with artificial insemination.

H. Rodríguez-Martínez, J. Thundathil, J. Gil, 1999, International journal of andrology.

Evaluation of an animal protein-free semen extender for cryopreservation of epididymal sperm from North American bison (Bison bison).

J. Thundathil, B. Elkin, D. Whiteside, 2011, Theriogenology.

Effects of culture medium and substrate on attachment of in vitro produced bovine embryos

J. Thundathil, I. Dobrinski, A. Dance, 2014 .

Role of Akt and mammalian target of rapamycin signalling in insulin-like growth factor 1-mediated cell proliferation in porcine Sertoli cells.

J. Kastelic, J. Thundathil, Chinju Johnson, 2020, Reproduction, fertility, and development.

A PRELIMINARY ASSESSMENT OF THE EFFECTS OF REPRODUCTIVE SEASONALITY ON SEMINAL PLASMA CHARACTERISTICS IN NORTH AMERICAN BISON (BISON BISON)

J. Thundathil, B. Elkin, D. Whiteside, 2017, Journal of zoo and wildlife medicine.

Testicular hyperthermia increases blood flow that maintains aerobic metabolism in rams.

J. Tyberg, J. Kastelic, J. Thundathil, 2019, Reproduction, fertility, and development.

In vitro fertilizing characteristics of bovine sperm with abnormal morphology

J. Thundathil, 2001 .

Enhanced pre-pubertal nutrition upregulates mitochondrial function in testes and sperm of post-pubertal Holstein bulls

J. Kastelic, J. Thundathil, I. Kovalchuk, 2020, Scientific Reports.

Proteins associated with critical sperm functions and sperm head shape are differentially expressed in morphologically abnormal bovine sperm induced by scrotal insulation.

J. Kastelic, J. Thundathil, A. Dance, 2013, Journal of proteomics.

Testis-Specific Isoform of Na/K-ATPase (ATP1A4) Interactome in Raft and Non-Raft Membrane Fractions from Capacitated Bovine Sperm

J. Kastelic, J. Thundathil, G. Rajamanickam, 2019, International journal of molecular sciences.