Kunihiko Kobayashi

发表

Involvement of PI3K/Akt/TOR pathway in stretch‐induced hypertrophy of myotubes

M. Sokabe, K. Hayakawa, N. Sasai, 2010, Muscle & nerve.

A. Gemma, Tomoaki Tanaka, S. Morita, 2010 .

Repetitive stretch suppresses denervation‐induced atrophy of soleus muscle in rats

M. Sokabe, K. Hayakawa, N. Sasai, 2009, Muscle & nerve.

Unique Epstein-Barr virus (EBV) latent gene expression, EBNA promoter usage and EBNA promoter methylation status in chronic active EBV infection.

Kunihiko Kobayashi, Xiaomin Ma, H. Kikuta, 2003, The Journal of general virology.

Relationship between gene polymorphisms of mannose‐binding lectin (MBL) and two molecular forms of MBL

Kunihiko Kobayashi, H. Kikuta, H. Miyakawa, 2003, European journal of immunology.

Analysis of incomplete quality of life data in advanced stage cancer: A practical application of multiple imputation

M. Shibuya, K. Eguchi, Y. Ohashi, 2005, Quality of Life Research.

A new risk-assessment tool for venous thromboembolism in advanced lung cancer: a prospective, observational study

Kunihiko Kobayashi, M. Yamasaki, T. Isobe, 2022, Journal of Hematology & Oncology.

First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy.

A. Gemma, Tomoaki Tanaka, S. Morita, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

BIWEEKLY ADMINISTRATION OF IRINOTECAN (CPT-11) PLUS CISPLATIN WITH AN ANTIDIARRHEAL PROGRAM OF INTESTINAL ALKALIZATION TO REDUCE DIARRHEA IN CANCER PATIENTS

S. Kudoh, Kunihiko Kobayashi, M. Kurihara, 2012 .

Early and presymptomatic detection of Wilson's disease at the mandatory 3-year-old medical health care examination in Hokkaido Prefecture with the use of a novel automated urinary ceruloplasmin assay.

T. Ariga, Kunihiko Kobayashi, K. Fujieda, 2008, Molecular genetics and metabolism.

Differential gene expression of S100 protein family in leukocytes from patients with Kawasaki disease

Kunihiko Kobayashi, T. Ebihara, Xiaomin Ma, 2005, European Journal of Pediatrics.

Biochemical Studies on Sulfate-reducing Bacteria

Kunihiko Kobayashi, E. Takahashi, M. Ishimoto, 1957 .

Wernicke encephalopathy in a lung cancer patient during treatment with nivolumab

Kunihiko Kobayashi, T. Akechi, H. Kagamu, 2018, Palliative and Supportive Care.

Effects of a Self-Monitoring Quality of Life Intervention for Patients with Cancer Receiving Palliative Care in Japan: Study Protocol for a Randomized Controlled Trial

T. Ohkubo, E. Matsushima, Kunihiko Kobayashi, 2018, Asian Pacific journal of cancer prevention : APJCP.

Combination therapy with carboplatin and paclitaxel for small cell lung cancer.

Kunihiko Kobayashi, H. Kagamu, O. Yamaguchi, 2019, Respiratory investigation.

Interstitial lung disease associated with gefitinib in Japanese patients with EGFR-mutated non-small-cell lung cancer: combined analysis of two Phase III trials (NEJ 002 and WJTOG 3405).

T. Mitsudomi, Y. Nakanishi, Kunihiko Kobayashi, 2013, Japanese journal of clinical oncology.

Reduced apolipoprotein E-rich high-density lipoprotein level at birth is restored to the normal range in patients with familial hypercholesterolemia in the first year of life.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2008, The Journal of clinical endocrinology and metabolism.

Evaluation of G-to-A substitution in the apolipoprotein A-I gene promoter as a determinant of high-density lipoprotein cholesterol level in subjects with and without cholesteryl ester transfer protein deficiency

Kunihiko Kobayashi, H. Chiba, S. Hui, 1995, Human Genetics.

Distinctive clinicopathological features of adenocarcinoma in situ and minimally invasive adenocarcinoma of the lung: A retrospective study.

Kunihiko Kobayashi, F. Sakai, H. Nitanda, 2019, Lung cancer.

Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.

Huqun, Tomoaki Tanaka, Kunihiko Kobayashi, 2005, Cancer research.

Pulmonary Tumor Embolism Due to Squamous Cell Carcinoma of the Uterine Cervix: A Case Report.

Kunihiko Kobayashi, F. Sakai, M. Yasuda, 2018, In vivo.

In vitro investigation of a combination of two drugs, cisplatin and carboplatin, as a function of the area under thec/t curve

S. Kudoh, Kunihiko Kobayashi, H. Niitani, 2005, Journal of Cancer Research and Clinical Oncology.

In vitro effect of antineoplastic agent on LAK activity

Kunihiko Kobayashi, H. Niitani, M. Hino, 1990 .

Weekly administration of irinotecan (CPT-11) plus cisplatin for refractory or relapsed small cell lung cancer.

A. Yoshimura, A. Gemma, T. Okano, 2004, Lung cancer.

Intestinal alkalization as a possible preventive mechanism in irinotecan (CPT-11)-induced diarrhea.

Y. Matsuzaki, Kunihiko Kobayashi, P. Latham, 2002, Cancer research.

PERSISTENT CYTOTOXICITY AFTER EXPOSURE TO ANTINEOPLASTIC AGENTS: THE SUCCINATE DEHYDROGENASE INHIBITION TEST RE-EXAMINED

S. Kudoh, Kunihiko Kobayashi, K. Hayashihara, 2008 .

Fluctuation of lipoprotein metabolism linked with bile acid-activated liver nuclear receptors in Alagille syndrome.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2008, Atherosclerosis.

Depletion of High-density Lipoprotein and Appearance of Triglyceride-rich Low-density Lipoprotein in a Japanese Patient With FIC1 Deficiency Manifesting Benign Recurrent Intrahepatic Cholestasis

H. Tsukahara, M. Hasegawa, Kunihiko Kobayashi, 2007, Journal of pediatric gastroenterology and nutrition.

Validity and Reliability of the Japanese Version of the 10-Item Perceived Efficacy in Patient-Physician Interactions (PEPPI-10) Scale in Breast Cancer Outpatients.

T. Ohkubo, Kenichi Inoue, K. Kubota, 2019, The Tohoku journal of experimental medicine.

Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 1

K. Kaga, Y. Okamoto, Kunihiko Kobayashi, 2006, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

A phase II study of first-line afatinib for patients aged ≥75 years with EGFR mutation-positive advanced non-small cell lung cancer: North East Japan Study Group trial NEJ027

A. Gemma, S. Morita, Kunihiko Kobayashi, 2020, BMC Cancer.

Risk factors for delayed elimination of high-dose methotrexate in childhood acute lymphoblastic leukemia and lymphoma

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2021, International Journal of Hematology.

Long‐term outcome of renal function in children after stem cell transplantation measured by estimated glomerular filtration rate

Kunihiko Kobayashi, D. Suzuki, S. Fujita, 2018, Pediatric Blood & Cancer.

Phase II study of nimustine hydrochloride (ACNU) plus paclitaxel for refractory small cell lung cancer.

A. Gemma, Kunihiko Kobayashi, K. Isobe, 2009, Lung cancer.

3) Non-small Cell Lung Cancer

Kunihiko Kobayashi, Kunihiko Kobayashi, K. Kobayashi, 2012 .

First-line gefitinib therapy for elder advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: Multicenter phase II trial (NEJ 003 study).

A. Gemma, Kunihiko Kobayashi, M. Maemondo, 2010 .

Quality of life with gefitinib in patients with EGFR-mutated non-small cell lung cancer: quality of life analysis of North East Japan Study Group 002 Trial.

A. Gemma, S. Morita, Kunihiko Kobayashi, 2012, The oncologist.

A phase II study of daily carboplatin plus irradiation followed by durvalumab for stage III non-small cell lung cancer patients with PS 2 up to 74 years old and patients with PS 0 or 1 from 75 years: NEJ039A (trial in progress)

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, BMC cancer.

A phase II study of bevacizumab with carboplatin-pemetrexed in non-squamous non-small cell lung carcinoma patients with malignant pleural effusions: North East Japan Study Group Trial NEJ013A.

Kunihiko Kobayashi, M. Maemondo, M. Nishitsuji, 2016, Lung cancer.

Carcinomatous meningitis and EGFR mutation

T. Okano, Kunihiko Kobayashi, A. Kawashima, 2015 .

The Peptide Nucleic Acid-Locked Nucleic Acid Polymerase Chain Reaction Clamp-Based Test for Epidermal Growth Factor Receptor Mutations in Bronchoscopic Cytological Specimens of Non-Small Cell Lung Cancer

M. Nishimura, Tomoaki Tanaka, Kunihiko Kobayashi, 2012, Oncology.

First-line gefitinib for elderly patients with advanced NSCLC harboring EGFR mutations. A combined analysis of North-East Japan Study Group studies

A. Gemma, Kunihiko Kobayashi, S. Oizumi, 2015, Expert opinion on pharmacotherapy.

Clinical Benefit of Chemotherapy for Small-Cell Lung Cancer Patients with Extremely Poor Performance Status (PS)

Kunihiko Kobayashi, H. Kagamu, O. Yamaguchi, 2018 .

Current status and future perspectives of cooperative study groups for lung cancer in Japan.

M. Tsuboi, Y. Ohe, H. Saka, 2014, Respiratory investigation.

Bevacizumab plus erlotinib versus erlotinib alone in Japanese patients with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival analysis of an open-label, randomised, multicentre, phase 3 trial.

M. Seike, M. Okada, S. Morita, 2021, The Lancet. Respiratory medicine.

A Phase II Study of Osimertinib Combined With Platinum Plus Pemetrexed in Patients With EGFR-Mutated Advanced Non-Small-cell Lung Cancer: The OPAL Study (NEJ032C/LOGIK1801).

M. Seike, K. Sugio, S. Morita, 2020, Clinical lung cancer.

Cross-cultural validation of the Japanese version of the lung cancer subscale on the functional assessment of cancer therapy-lung.

Kunihiko Kobayashi, S. Eremenco, Chih-Hung Chang, 2007, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

Hemithoracic intensity-modulated radiotherapy using helical tomotherapy for patients after extrapleural pneumonectomy for malignant pleural mesothelioma.

Takeo Takahashi, T. Nakano, Kunihiko Kobayashi, 2012, Journal of radiation research.

Sarcopenia after induction therapy in childhood acute lymphoblastic leukemia: its clinical significance

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2018, International Journal of Hematology.

Spontaneous remission of 2-chlorodeoxyadenosine (2-CdA)-related secondary myelodysplastic syndrome in a patient with refractory Langerhans cell histiocytosis

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2013, International journal of hematology.

Degalactosylated and/or Denatured IgA, but Not Native IgA in Any Form, Bind to Mannose-Binding Lectin1

Kunihiko Kobayashi, I. Terai, N. Mafune, 2006, The Journal of Immunology.

Mannose-Binding Lectin Not Native IgA in Any Form , Bind to Degalactosylated and / or Denatured IgA

Kunihiko Kobayashi, 2006 .

Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis

Kunihiko Kobayashi, T. Ebihara, Xiaomin Ma, 2002, Journal of Clinical Microbiology.

Illness Perceptions and Quality of Life in Patients with Non-Small-Cell Lung Cancer: A 3-Month Follow-Up Pilot Study

H. Putter, J. Nortier, Kenichi Inoue, 2020, Patient related outcome measures.

A Glycoprotein Secreted by Lung Cancer Cells Is Present in Human Serum as an Immunoglobulin‐binding Protein

Kunihiko Kobayashi, N. Nonaka, Hidematsu Hirai (deceased), 1994, Japanese journal of cancer research : Gann.

Detailed Characterization of a High‐molecular‐weight Glycoprotein Secreted by Lung Cancer Cells

Kunihiko Kobayashi, N. Nonaka, K. Manaka, 1993, Japanese journal of cancer research : Gann.

Effects of bezafibrate on dyslipidemia with cholestasis in children with familial intrahepatic cholestasis-1 deficiency manifesting progressive familial intrahepatic cholestasis.

H. Tsukahara, S. Uemoto, Kunihiko Kobayashi, 2009, Metabolism: clinical and experimental.

Evaluation of risk for atherosclerosis in Alagille syndrome and progressive familial intrahepatic cholestasis: two congenital cholestatic diseases with different lipoprotein metabolisms.

M. Hasegawa, Kunihiko Kobayashi, H. Chiba, 2005, The Journal of pediatrics.

Apolipoprotein E (ApoE) and ApoE-rich high-density cholesterol as potential early diagnostic markers of congenital biliary tract anomalies.

Kunihiko Kobayashi, H. Chiba, T. Yorifuji, 2003, The Journal of pediatrics.

Comparison of Methods for Profiling O-Glycosylation

Nicolle H. Packer, Naoyuki Taniguchi, Daniel Kolarich, 2009, Molecular & Cellular Proteomics.

Altered metabolisms of mediators controlling vascular function and enhanced oxidative stress in asymptomatic children with congenital portosystemic venous shunt.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2010, Metabolism: clinical and experimental.

Relationship Between Oxidative Stress and Antioxidant Systems in the Liver of Patients With Wilson Disease: Hepatic Manifestation in Wilson Disease as a Consequence of Augmented Oxidative Stress

H. Tsukahara, S. Uemoto, Kunihiko Kobayashi, 2006, Pediatric Research.

Validation Study of a Disease-specific Module, the Asthma Health Questionnaire (AHQ) Using Japanese Adult Asthmatic Patients

Kunihiko Kobayashi, K. Kudo, H. Arioka, 2005 .

Mild immunoglobulin A nephropathy in a patient with a marked increase in serum immunoglobulin A

Kunihiko Kobayashi, K. Hayasaka, T. Mitsui, 2004, Pediatrics international : official journal of the Japan Pediatric Society.

Apolipoproteins in rat cerebrospinal fluid: A comparison with plasma lipoprotein metabolism and effect of aging

Kunihiko Kobayashi, K. Tashiro, A. Ogata, 1991, Neuroscience Letters.

CHEMORADIOTHERAPY FOR NON-SMALL CELL LUNG CANCER

Kunihiko Kobayashi, 2003 .

Impact of folate therapy on combined immunodeficiency secondary to hereditary folate malabsorption.

M. Yamada, Natsuko Chida, Kunihiko Kobayashi, 2014, Clinical immunology.

CD36 deficiency and insulin resistance

Kunihiko Kobayashi, H. Chiba, H. Yanai, 2001, The Lancet.

Study of upper respiratory tract bacterial flora: first report. Variations in upper respiratory tract bacterial flora in patients with acute upper respiratory tract infection and healthy subjects and variations by subject age

K. Kaga, Y. Okamoto, Kunihiko Kobayashi, 2006, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Efficacy of Antibiotic Prophylaxis for Intrafamilial Transmission of Group A β-Hemolytic Streptococci

Kunihiko Kobayashi, H. Sakata, H. Kikuta, 2007, The Pediatric infectious disease journal.

Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis.

Huqun, S. Abe, Y. Inoue, 2007, American journal of respiratory and critical care medicine.

Transgene of MIF induces podocyte injury and progressive mesangial sclerosis in the mouse kidney.

Kunihiko Kobayashi, Y. Sado, Y. Ninomiya, 2004, Kidney international.

Study of nasopharyngeal bacterial flora. Variations in nasopharyngeal bacterial flora in schoolchildren and adults when administered antimicrobial agents

K. Kaga, Y. Okamoto, Kunihiko Kobayashi, 2007, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Wiskott-Aldrich syndrome with unusual clinical features similar to juvenile myelomonocytic leukemia

M. Yamada, Kunihiko Kobayashi, D. Suzuki, 2012, International Journal of Hematology.

A Rat Model for Arrest of Alveolarization Induced by Antenatal Endotoxin Administration

Kunihiko Kobayashi, H. Minakami, Kazutoshi Cho, 2006, Pediatric Research.

Prognostic Potential of Metabolic Activity on 18F-FDG Accumulation in Advanced NSCLC Receiving Combining Chemotherapy Plus PD-1 Blockade

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2022, Journal of immunotherapy.

Latency pattern of Epstein‐Barr virus and methylation status in Epstein‐Barr virus‐associated hemophagocytic syndrome

Kunihiko Kobayashi, H. Kikuta, N. Ishiguro, 2003, Journal of medical virology.

Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus

Kunihiko Kobayashi, H. Ishiko, T. Ebihara, 2004, Journal of medical virology.

Seroprevalence of human metapneumovirus in Japan

Kunihiko Kobayashi, T. Ebihara, Xiaomin Ma, 2003, Journal of medical virology.

Phase III study comparing bevacizumab plus erlotinib to erlotinib in patients with untreated NSCLC harboring activating EGFR mutations: NEJ026.

A. Gemma, M. Okada, S. Morita, 2018 .

Phase III study comparing gefitinib monotherapy (G) to combination therapy with gefitinib, carboplatin, and pemetrexed (GCP) for untreated patients (pts) with advanced non-small cell lung cancer (NSCLC) with EGFR mutations (NEJ009).

A. Gemma, Y. Hosomi, S. Morita, 2018 .

Phase I/II study of nedaplatin and nab-paclitaxel for patients with previously untreated advanced squamous cell lung cancer: Kanto Respiratory Disease Study Group (KRSG) 1302

K. Mori, Kunihiko Kobayashi, T. Kasai, 2022, International Journal of Clinical Oncology.

Clonal expansion of multiphenotypic Epstein-Barr virus-infected lymphocytes in chronic active Epstein-Barr virus infection.

Kunihiko Kobayashi, T. Ebihara, H. Kikuta, 2004, Medical hypotheses.

Phase II Study of Amrubicin Combined with Carboplatin for Thymic Carcinoma and Invasive Thymoma: North Japan Lung Cancer Group Study 0803

Kunihiko Kobayashi, M. Maemondo, T. Nukiwa, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Successful Treatment of Mediastinal γδ T-Cell Lymphoblastic Lymphoma in a 3-Year-Old Girl by Allogeneic Cord Blood Transplantation.

Kunihiko Kobayashi, N. Kiyokawa, D. Suzuki, 2017, Journal of pediatric hematology/oncology.

Pediatric nodal marginal zone lymphoma in a Japanese boy

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2017, Pediatrics international : official journal of the Japan Pediatric Society.

No mutations of SAP/SH2D1A/DSHP and perforin genes in patients with Epstein‐Barr virus‐associated hemophagocytic syndrome in Japan

Kunihiko Kobayashi, Xiaomin Ma, H. Kikuta, 2001, Journal of medical virology.

Incidence of venous thromboembolism in advanced lung cancer and efficacy and safety of direct oral anticoagulants: a multicenter, prospective, observational study (Rising-VTE/NEJ037 study)

Kunihiko Kobayashi, H. Ohtsu, M. Yamasaki, 2021, Therapeutic advances in medical oncology.

Congenital Dermatofibrosarcoma Protuberans in a Newborn Infant With a Massive Back Tumor: Favorable Effects of Oral Imatinib on the Control of Residual Tumor Growth

Kunihiko Kobayashi, D. Suzuki, Keita Morioka, 2011, Journal of pediatric hematology/oncology.

Structure of spirituality among high-school students differs depending on relationship with someone or something Greater (RSG)

Kunihiko Kobayashi, Kensho Ohata, Takuya Gonokami, 2022, Current Psychology.

Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study.

A. Gemma, Y. Hosomi, S. Morita, 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Irinotecan (CPT-11) in combination with weekly administration of cisplatin (CDDP) for non-small-cell lung cancer

S. Hibino, M. Shibuya, Kunihiko Kobayashi, 1998, Cancer Chemotherapy and Pharmacology.

Peripherally Inserted Central Venous Catheter for Pediatric and Young Adult Patients With Hematologic and Malignant Diseases

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2020, Journal of pediatric hematology/oncology.

A solid-phase radioimmunoassay for human 3-microglobulin

Kunihiko Kobayashi, I. Matsuda, N. Taniguchi, 1976 .

Immunohistochemical analysis of Mallory bodies in Wilsonian and non‐Wilsonian hepatic copper toxicosis

K. Zatloukal, H. Denk, C. Langner, 2004, Hepatology.

Kinetic Analysis of Combination Effect of Navelbine (KW‐2307) with Cisplatin against Human Lung Adenocarcinoma PC‐12 Cells in Culture

K. Gomi, M. Okabe, Kunihiko Kobayashi, 1992, Japanese Journal of Cancer Research : Gann.

Plasma protein C is a useful clinical marker for hepatic veno‐occlusive disease (VOD) in stem cell transplantation

Kunihiko Kobayashi, R. Kobayashi, A. Iguchi, 2010, Pediatric blood & cancer.

Prophylactic administration of voriconazole with two different doses for invasive fungal infection in children and adolescents with acute myeloid leukemia.

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2016, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

Impact of muscle loss in children with hematologic malignancies undergoing allogeneic hematopoietic cell transplantation

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2022, International Journal of Hematology.

Weekly administration of irinotecan (CPT-11) plus cisplatin for non-small cell lung cancer.

A. Yoshimura, A. Gemma, S. Kudoh, 2006, Anticancer research.

Tumor immunity is related to 18F‐FDG uptake in thymic epithelial tumor

Kunihiko Kobayashi, T. Kawasaki, K. Kaira, 2020, Cancer medicine.

Comparison of a Lateral-Flow Immunochromatography Assay with Real-Time Reverse Transcription-PCR for Detection of Human Metapneumovirus

Kunihiko Kobayashi, H. Ishiko, Akio Hayashi, 2008, Journal of Clinical Microbiology.

Phase II study of bi-weekly docetaxel and carboplatin with concurrent thoracic radiation therapy followed by consolidation chemotherapy with docetaxel plus carboplatin for stage III unresectable non-small cell lung cancer.

Kunihiko Kobayashi, S. Yoneda, H. Sakai, 2004, Lung cancer.

Comparison of myelosuppression using the D‐index between children and adolescents/young adults with acute lymphoblastic leukemia during induction chemotherapy

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2020, Pediatric blood & cancer.

Differential efficacy of empirical antibiotic therapy for febrile neutropenia in adolescent/young adult (AYA) and child patients

Kunihiko Kobayashi, D. Suzuki, Makoto Yoshida, 2018, International Journal of Hematology.

A direct enzyme immunoassay for 18-hydroxycortisol in urine: A new tool for screening primary aldosteronism

Kunihiko Kobayashi, H. Chiba, T. Yoshimura, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

Development of nephrotic syndrome during immunosuppressive treatment for aplastic anaemia with monosomy 7 in a 16-year-old boy: A case report.

Kunihiko Kobayashi, M. Yanagi, R. Kobayashi, 2022, Journal of paediatrics and child health.

Nitric oxide synthesis in ornithine transcarbamylase deficiency: possible involvement of low no synthesis in clinical manifestations of urea cycle defect.

Kunihiko Kobayashi, K. Murayama, T. Yorifuji, 2004, The Journal of pediatrics.

Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2009, Metabolism: clinical and experimental.

Clinical Outcomes after One-day or Two-day Intervals in Conditioning Regimens for allo-HCT

Kunihiko Kobayashi, M. Yanagi, R. Kobayashi, 2022, Journal of pediatric hematology/oncology.

Updated Analysis of NEJ009: Gefitinib-Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated EGFR

Y. Hosomi, M. Seike, S. Morita, 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Meropenem versus piperacillin/tazobactam with or without immunoglobulin as second-line therapy for febrile neutropenia in pediatric patients.

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2017, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

Radiotherapy concurrently with weekly cisplatin, followed by adjuvant chemotherapy, for N2–3 nasopharyngeal cancer: a multicenter trial of the Forum for Nuclear Cooperation in Asia

T. Nakano, T. Ohno, H. Tsujii, 2012, Journal of radiation research.

Identification of risk factors for venous thromboembolism and validation of the Khorana score in patients with advanced lung cancer: based on the multicenter, prospective Rising-VTE/NEJ037 study data

Kunihiko Kobayashi, M. Yamasaki, T. Isobe, 2022, International Journal of Clinical Oncology.

Epstein–Barr virus‐associated B‐cell lymphoma in a patient with DNA ligase IV (LIG4) syndrome

K. Ohshima, M. Yamada, I. Kobayashi, 2007, American journal of medical genetics. Part A.

Meropenem versus piperacillin/tazobactam for febrile neutropenia in pediatric patients: efficacy of piperacillin/tazobactam as a 1-h drip infusion four times a day

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2020, International Journal of Hematology.

Establishing a whole blood CD4+ T cell immunity measurement to predict response to anti-PD-1

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2022, BMC cancer.

Successful pneumonectomy for invasive pulmonary aspergillosis and advanced non-small cell-lung cancer

Kunihiko Kobayashi, H. Ishida, N. Koyama, 2013, BMJ Case Reports.

Comparison between piperacillin/tazobactam and cefepime monotherapies as an empirical therapy for febrile neutropenia in children with hematological and malignant disorders: A prospective, randomized study

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2015, Pediatric blood & cancer.

Lower gamma globulin level before conditioning is a risk factor for cytomegalovirus antigenemia after pediatric allogeneic stem cell transplantation

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2018, Pediatric blood & cancer.

A survey of hypercalciuria during chemotherapy in acute lymphoblastic leukemia

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2020, Pediatrics international : official journal of the Japan Pediatric Society.

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an open-label, randomised, multicentre, phase 3 trial.

A. Gemma, M. Okada, S. Morita, 2019, The Lancet. Oncology.

Psychosocial domain in quality of life as an independent prognostic factor for survival and tumor response in patients with advanced non-small cell lung cancer (NSCLS)

Satoshi Morita, Yasuo Ohashi, Kenji Eguchi, 2000 .

Recovery of the Sensitivity to Anti-PD-1 Antibody by Celecoxib in Lung Cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, AntiCancer Research.

Successful treatment of immune tolerance induction with rituximab in a patient with severe hemophilia B and inhibitor.

Kunihiko Kobayashi, D. Suzuki, S. Fujita, 2015, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Brainstem activates paroxysmal discharge in human generalized epilepsy

S. Kohsaka, Kunihiko Kobayashi, S. Mizukami, 2001, Brain Research.

First-Line Gefitinib in Patients Aged 75 or Older With Advanced Non–Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations: NEJ 003 Study

S. Kudoh, Tomoaki Tanaka, Kunihiko Kobayashi, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Combined Survival Analysis of Prospective Clinical Trials of Gefitinib for Non–Small Cell Lung Cancer with EGFR Mutations

Koichi Yamazaki, Satoshi Morita, Masahiro Fukuoka, 2009, Clinical Cancer Research.

Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.

Eiji Katsura, Kunihiko Kobayashi, S. Takeuchi, 2004, Environmental health perspectives.

Voriconazole Concentrations in Cerebrospinal Fluid During Prophylactic Use in Children with Acute Myelogenous Leukemia

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2016, The Pediatric infectious disease journal.

Factors Influencing Pulmonary Surfactant Protein A Levels in Cord Blood, Maternal Blood and Amniotic Fluid

Kunihiko Kobayashi, Kazutoshi Cho, Y. Matsumoto, 1998, Neonatology.

Real-world outcomes of chemotherapy for lung cancer patients undergoing hemodialysis: A multicenter retrospective cohort study (NEJ-042).

M. Seike, Kunihiko Kobayashi, T. Harada, 2022, Lung cancer.

Bacteremia during neutropenia is a predictive factor for invasive fungal infection in children

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2013, Pediatrics international : official journal of the Japan Pediatric Society.

Analysis of Hypokalemia as a Side Effect of Liposomal Amphotericin in Pediatric Patients

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2017, The Pediatric infectious disease journal.

Successful Treatment with Methylprednisolone Pulse Therapy for a Life-Threatening Pulmonary Insufficiency in a Patient with Chronic Granulomatous Disease following Pulmonary Invasive Aspergillosis and Burkholderia cepacia Infection

M. Yamada, Kunihiko Kobayashi, Y. Sakiyama, 1999, Respiration.

Efficacy of liposomal amphotericin against febrile neutropenia in pediatric patients receiving prophylactic voriconazole

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2020, Pediatrics international : official journal of the Japan Pediatric Society.

Stem cell transplantation for acute myeloid leukemia with pulmonary and cerebral mucormycosis

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2016, Pediatrics international : official journal of the Japan Pediatric Society.

HIRA-TAN: a real-time PCR-based system for the rapid identification of causative agents in pneumonia.

Minoru Kanazawa, Koichi Hagiwara, Koichi Fukunaga, 2014, Respiratory medicine.

Risk Factors for Invasive Fungal Infection in Children and Adolescents With Hematologic and Malignant Diseases: A 10-year Analysis in a Single Institute in Japan

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2018, The Pediatric infectious disease journal.

Impact of the D-index deduced from duration and intensity of neutropenia following chemotherapy on the risk of invasive fungal infection in pediatric acute myeloid leukemia

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2018, International Journal of Hematology.

A prospective randomized trial comparing piperacillin/tazobactam with meropenem as empirical antibiotic treatment of febrile neutropenic children and adolescents with hematologic and malignant disorders

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2017, Pediatric blood & cancer.

Acute promyelocytic leukemia after living donor partial orthotopic liver transplantation in two Japanese girls

Kunihiko Kobayashi, H. Furukawa, R. Kobayashi, 2005, Leukemia & lymphoma.

Spontaneous improvement in a pediatric patient with peripheral T‐cell lymphoma

Kunihiko Kobayashi, D. Suzuki, A. Nakazawa, 2015, Pediatrics international : official journal of the Japan Pediatric Society.

Effects of midstream collection and the menstrual cycle on urine particles and dipstick urinalysis among healthy females.

Kunihiko Kobayashi, H. Chiba, H. Yanai, 2003, Clinical chemistry.

Refractory Sacrococcygeal Germ Cell Tumor in Schinzel-Giedion Syndrome

H. Tonoki, Kunihiko Kobayashi, D. Suzuki, 2015, Journal of pediatric hematology/oncology.

Genetic studies of three Japanese patients with p22‐phox‐deficient chronic granulomatous disease: detection of a possible common mutant CYBA allele in Japan and a genotype–phenotype correlation in these patients

M. Yamada, T. Ariga, Kunihiko Kobayashi, 2000, British journal of haematology.

Frequency of and variables associated with the EGFR mutation and its subtypes

A. Gemma, K. Uematsu, Tomoaki Tanaka, 2010, International journal of cancer.

A 25-Year Observation of a Japanese Female Patient with Hb Nottingham who has Two Children with the Same Disorder

T. Ariga, Kunihiko Kobayashi, Y. Hatae, 2012, Hemoglobin.

Development of Quality of Life Questionnaire in Japan: quality of life assessment of cancer patients receiving chemotherapy 1

K. Eguchi, Kunihiko Kobayashi, M. Kurihara, 1999, Psycho-oncology.

Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency

Kunihiko Kobayashi, Shigenori Yamamoto, K. Murayama, 2006, European Journal of Pediatrics.

Detection of human herpesvirus 8 DNA sequences in peripheral blood mononuclear cells of children

T. Ariga, Kunihiko Kobayashi, H. Kikuta, 1997 .

CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy

K. Horimoto, K. Fukui, M. Kitazawa, 2019, Cancer Immunology Research.

4 and other hand , the Bcl-2 proto-oncogene product ( Bakhshi

Y. Tsujimoto, S. Shimizu, Kunihiko Kobayashi, 2013 .

Clinical Significance of Tumor Markers for Advanced Thymic Carcinoma: A Retrospective Analysis from the NEJ023 Study

Kazuhisa Takahashi, Kunihiko Kobayashi, M. Yamasaki, 2022, Cancers.

Antibody against the human J chain inhibits polymeric Ig receptor‐mediated biliary and epithelial transport of human polymeric IgA

Kunihiko Kobayashi, I. Moro, P. Brandtzaeg, 1998 .

Prognostic factors for patients with metastatic or recurrent thymic carcinoma receiving palliative-intent chemotherapy.

S. Morita, Kazuhisa Takahashi, S. Yamanda, 2020, Lung cancer.

Prognostic Factors and Efficacy of First-Line Chemotherapy in Patients with Advanced Thymic Carcinoma: A Retrospective Analysis of 286 Patients from NEJ023 Study.

S. Morita, Kazuhisa Takahashi, Kunihiko Kobayashi, 2018, The oncologist.

Effectiveness of Gefitinib against Non–Small-Cell Lung Cancer with the Uncommon EGFR Mutations G719X and L861Q

Koichi Hagiwara, Yuji Minegishi, Akira Inoue, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Analysis of antibiotics discontinuation during bone marrow suppression in childhood, adolescent and young adult patients with febrile neutropenia.

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2020, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

A prospective, randomized study comparing cefozopran with piperacillin–tazobactam plus ceftazidime as empirical therapy for febrile neutropenia in children with hematological disorders

Kunihiko Kobayashi, R. Kobayashi, A. Iguchi, 2008, Pediatric blood & cancer.

Efficacy and Feasibility of Programmed Death-1/Programmed Death Ligand-1 Blockade Therapy in Non-Small Cell Lung Cancer Patients With High Antinuclear Antibody Titers

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Frontiers in Oncology.

Effect of meropenem with or without immunoglobulin as second‐line therapy for pediatric febrile neutropenia

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2014, Pediatrics international : official journal of the Japan Pediatric Society.

A phase II study of carboplatin and etoposide plus durvalumab for previously untreated extensive-stage small-cell lung cancer (ES-SCLC) patients with a poor performance status (PS): NEJ045A study protocol

Kunihiko Kobayashi, Satoshi Watanabe, T. Asao, 2022, BMC Cancer.

[Hange-Shashin-to for preventing diarrhea during afatinib therapy].

T. Okano, Kunihiko Kobayashi, A. Kawashima, 2015, Gan to kagaku ryoho. Cancer & chemotherapy.

Phase II study of amrubicin (AMR) and carboplatin (CBDCA) for invasive thymoma (IT) and thymic carcinoma (TC): NJLCG0803.

Kunihiko Kobayashi, M. Maemondo, T. Nukiwa, 2013 .

Efficacy of triple antiemetic therapy (palonosetron, dexamethasone, aprepitant) for chemotherapy-induced nausea and vomiting in patients receiving carboplatin-based, moderately emetogenic chemotherapy

A. Gemma, M. Seike, K. Kubota, 2016, SpringerPlus.

A. Gemma, M. Seike, K. Kubota, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Combination chemotherapy of alternating etoposide and carboplatin with weekly administration of irinotecan and cisplatin in extensive-stage small-cell lung cancer.

A. Yoshimura, A. Gemma, T. Okano, 2012, Anticancer research.

A highly specific and sensitive massive parallel sequencer-based test for somatic mutations in non-small cell lung cancer

Kunihiko Kobayashi, M. Tsuchida, H. Miyazawa, 2017, PloS one.

Multicentre real-world data of ramucirumab plus docetaxel after combined platinum-based chemotherapy with programmed death-1 blockade in advanced non-small cell lung cancer: NEJ051 (REACTIVE study).

Kunihiko Kobayashi, K. Kaira, K. Mori, 2023, European journal of cancer.

Prognostic significance of tumor infiltrating lymphocytes on first-line pembrolizumab efficacy in advanced non-small cell lung cancer

Kunihiko Kobayashi, T. Kawasaki, K. Kaira, 2023, Discover Oncology.

Pretreatment body mass index predicts survival among patients administered nivolumab monotherapy for pretreated non‐small cell lung cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2022, Thoracic cancer.

Visual Assessment of 18F-FDG Uptake on PET to Predict Survival Benefit to PD-1 Blockade in Non–Small Cell Lung Cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2022, Clinical nuclear medicine.

Pretreatment Glasgow prognostic score predicts survival among patients with high PD‐L1 expression administered first‐line pembrolizumab monotherapy for non‐small cell lung cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Cancer medicine.

Effect of Systemic Steroid Use for Immune-Related Adverse Events in Patients with Non-Small Cell Lung Cancer Receiving PD-1 Blockade Drugs

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Journal of clinical medicine.

Post-Progression Survival Influences Overall Survival among Patients with Advanced Non-Small Cell Lung Cancer Undergoing First-Line Pembrolizumab Monotherapy

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Oncology.

Efficacy and Safety of Anti-Programed Death-1 Blockade in Previously Treated Large-Cell Neuroendocrine Carcinoma

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Chemotherapy.

Clinical impact of post‐progression survival on overall survival in patients receiving nivolumab monotherapy as a second‐line treatment for advanced non‐small cell lung cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Thoracic cancer.

Pre‐existing interstitial lung disease does not affect prognosis in non‐small cell lung cancer patients with PD‐L1 expression ≥50% on first‐line pembrolizumab

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, Thoracic cancer.

Tumor metabolic volume by 18F-FDG-PET as a prognostic predictor of first-line pembrolizumab for NSCLC patients with PD-L1 ≥ 50%

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, Scientific Reports.

Chemoradiotherapy followed by durvalumab in patients with unresectable advanced non‐small cell lung cancer: Management of adverse events

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, Thoracic cancer.

Potential of FDG-PET as Prognostic Significance after anti-PD-1 Antibody against Patients with Previously Treated Non-Small Cell Lung Cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, Journal of clinical medicine.

Severe hepatotoxicity due to osimertinib after nivolumab therapy in patients with non‐small cell lung cancer harboring EGFR mutation

Kunihiko Kobayashi, T. Kawasaki, K. Kaira, 2020, Thoracic cancer.

Clinical difference between discontinuation and retreatment with nivolumab after immune-related adverse events in patients with lung cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Cancer Chemotherapy and Pharmacology.

Radiotherapy is an independent prognostic marker of favorable prognosis in non‐small cell lung cancer patients after treatment with the immune checkpoint inhibitor, nivolumab

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Thoracic cancer.

Clinical significance of primary prophylactic pegylated‐granulocyte‐colony stimulating factor after the administration of ramucirumab plus docetaxel in patients with previously treated non‐small cell lung cancer

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Thoracic cancer.

Improved efficacy of ramucirumab plus docetaxel after nivolumab failure in previously treated non‐small cell lung cancer patients

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Thoracic cancer.

Correction to: Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Cancer Chemotherapy and Pharmacology.

Successful treatment of carcinomatous meningitis with erlotinib and whole brain radiotherapy

T. Okano, Kunihiko Kobayashi, H. Sakaguchi, 2012 .

Clinical significance of circulating tumor cells and free DNA in non-small cell lung cancer.

Kunihiko Kobayashi, K. Isobe, K. Sugino, 2012, Anticancer research.

Efficacy of chemotherapy after first-line gefitinib therapy in EGFR mutation-positive advanced non-small cell lung cancer-data from a randomized Phase III study comparing gefitinib with carboplatin plus paclitaxel (NEJ002).

A. Gemma, Kunihiko Kobayashi, S. Oizumi, 2015, Japanese journal of clinical oncology.

Epidermal growth factor receptor (EGFR) mutation and personalized therapy in advanced nonsmall cell lung cancer (NSCLC)

Kunihiko Kobayashi, K. Hagiwara, K. Kobayashi, 2013, Targeted Oncology.

Phase 2 study of osimertinib in combination with platinum and pemetrexed in patients with previously untreated EGFR-mutated advanced non-squamous non-small cell lung cancer: The OPAL Study.

M. Seike, K. Sugio, Kunihiko Kobayashi, 2023, European journal of cancer.

Osimertinib in poor performance status patients with T790M-positive advanced non-small-cell lung cancer after progression of first- and second-generation EGFR-TKI treatments (NEJ032B)

S. Morita, Kunihiko Kobayashi, M. Maemondo, 2021, International Journal of Clinical Oncology.

Phase I Study Evaluating the Combination of Afatinib with Carboplatin and Pemetrexed After First-line EGFR-TKIs

Kunihiko Kobayashi, T. Nukiwa, T. Kikuchi, 2018, Anticancer Research.

Updated survival outcomes of NEJ005/TCOG0902: a randomised phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations

A. Gemma, S. Morita, Kunihiko Kobayashi, 2018, ESMO Open.

Treatments and outcomes of advanced/recurrent non-small cell lung cancer harboring the EGFR T790M mutation: a retrospective observational study of 141 patients in Japan.

Y. Ishii, Kunihiko Kobayashi, Makoto Nishino, 2016, Japanese journal of clinical oncology.

Factors associated with a poor response to gefitinib in the NEJ002 study: smoking and the L858R mutation.

A. Gemma, S. Morita, Kunihiko Kobayashi, 2015, Lung cancer.

Ann. Cancer Res. Ther. Vol. 23, No. 1, pp. 14-18, 2015

T. Okano, Kunihiko Kobayashi, A. Kawashima, 2015 .

Importance of the cytological samples for the epidermal growth factor receptor gene mutation test for non‐small cell lung cancer

Kunihiko Kobayashi, K. Hagiwara, K. Kobayashi, 2013, Cancer science.

Current Status and Future Directions of Radiotherapy and Chemotherapy for Locally Advanced Non-small Cell Lung Cancer

Kunihiko Kobayashi, H. Akiyama, A. Masumoto, 2013 .

Low-Dose Gefitinib Treatment for Patients with Advanced Non-small Cell Lung Cancer Harboring Sensitive Epidermal Growth Factor Receptor Mutations

A. Gemma, Kunihiko Kobayashi, S. Oizumi, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

c-kit Activating Mutations and Mast Cell Proliferation in Human Leukemia

M. Peitsch, A. Fischer, W. Friedrich, 2017 .

Blood Mononuclear Cells Syndrome Protein Expression in Peripheral Cytometric Analysis of Wiskott-Aldrich Wiskott-Aldrich Syndrome by Flow Determination of Carrier Status for the Kobayashi and Yukio

M. Yamada, I. Kobayashi, T. Ariga, 2000 .

Early diagnosis for polyarthritis of juvenile idiopathic arthritis using systemic gallium scintigraphy

I. Kobayashi, Kunihiko Kobayashi, M. Okano, 2009, Pediatrics international : official journal of the Japan Pediatric Society.

Two sibling cases of hydrops fetalis due to alloimmune anti-CD36 (Naka) antibody

M. Yamaguchi, T. Ariga, Kunihiko Kobayashi, 2006, Thrombosis and Haemostasis.

Human Metapneumovirus Infection in Japanese Children

Kunihiko Kobayashi, H. Ishiko, T. Ebihara, 2004, Journal of Clinical Microbiology.

Phenotype-genotype Correlation in CD36 Deficiency Types I and II

Kunihiko Kobayashi, H. Chiba, H. Yanai, 2000, Thrombosis and Haemostasis.

Syndrome Inherited Mutation in the Wiskott-Aldrich Spontaneous In Vivo Reversion of an Sakiyama

M. Yamada, T. Ariga, Kunihiko Kobayashi, 2001 .

Protein-Losing Cytomegalovirus Gastritis in a Patient with Stevens-Johnson Syndrome

J. Kodaira, Kunihiko Kobayashi, Xiaomin Ma, 2002, Digestion.

pH‐dependent uptake of irinotecan and its active metabolite, SN‐38, by intestinal cells

S. Kudoh, Y. Matsuzaki, Kunihiko Kobayashi, 1999, International journal of cancer.

Clinical significance of serum total bile acids and indocyanine green test for the estimation of plasma free etoposide ratio in anicteric hepatocellular carcinoma patients

N. Tanaka, Y. Matsuzaki, Kunihiko Kobayashi, 1997 .

Prediction of the Pathogens That Are the Cause of Pneumonia by the Battlefield Hypothesis

Hitoshi Miyazawa, Satoshi Morita, Minoru Kanazawa, 2011, PloS one.

Lung cancer patients frequently visit the emergency room for cancer-related and -unrelated issues.

Kunihiko Kobayashi, M. Nemoto, H. Sakaguchi, 2014, Molecular and clinical oncology.

Primary thymic adenocarcinoma with an aggressive clinical course: An autopsy case showing signet ring cell‐like features

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2020, Thoracic cancer.

Resistance to Parathyroid Hormone in Two Patients with Familial Intrahepatic Cholestasis: Possible Involvement of the ATP8B1 Gene in Calcium Regulation via Parathyroid Hormone

M. Hasegawa, Kunihiko Kobayashi, K. Murayama, 2004, Journal of pediatric gastroenterology and nutrition.

Perceptions of Japanese and Dutch women with early breast cancer about monitoring their quality of life

H. Putter, J. Nortier, Kenichi Inoue, 2021, Journal of psychosocial oncology.

Amino-terminus truncated apolipoprotein E is the major species in amyloid deposits in Alzheimer's disease-affected brains: a possible role for apolipoprotein E in Alzheimer's disease

Kunihiko Kobayashi, H. Chiba, N. Fujii, 1997, Brain Research.

Co-localization of amyloid-associated proteins with amyloid β in rat soleus muscle in chloroquine-induced myopathy: a possible model for amyloid β formation in Alzheimer's disease

Nobuhiro Fujii, Yuji Takamaru, Taku Yoshida, 1995, Brain Research.

Identification and Role of Non-Beta Components of Senile Plaque Amyloid in Alzheimer’s Disease

Kunihiko Kobayashi, H. Chiba, N. Fujii, 1995 .

Favorable effect of 4-phenylacetate on liver functions attributable to enhanced bile salt export pump expression in ornithine transcarbamylase-deficient children.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2010, Molecular Genetics and Metabolism.

Risk factors for sepsis-related death in children and adolescents with hematologic and malignant diseases.

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2017, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

Tumor lysis syndrome as a risk factor for posterior reversible encephalopathy syndrome in children with hematological malignancies

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2014, International Journal of Hematology.

Bicarbonate Attenuates Irinotecan-Induced Cytotoxicity through Regulation of Both Extracellular and Intracellular pHs in Intestine Cell Line

T. Miyazaki, Y. Matsuzaki, Kunihiko Kobayashi, 2013 .

High Genetic Diversity of the Attachment (G) Protein of Human Metapneumovirus

Kunihiko Kobayashi, H. Ishiko, T. Ebihara, 2004, Journal of Clinical Microbiology.

Analysis of Risk Factors for Hyponatremia During or Following Chemotherapy in Children With Cancer: A Hospital-based, Retrospective Cohort Study

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2016, Journal of pediatric hematology/oncology.

Metachronous lesions in the orbit, retroperitoneum, and pleura of mucosa‐associated lymphoid tissue lymphoma: A case report

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2022, Cancer reports.

Assessment of Coronary Function in Children With a History of Kawasaki Disease Using 15O-Water Positron Emission Tomography

N. Tamaki, Kunihiko Kobayashi, C. Katoh, 2002, Circulation.

Successful treatment of steroid-dependent gastrointestinal acute graft-versus-host disease with mesenchymal stromal cells administered more than 100 days after allo-HCT

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2022, Blood cell therapy.

A deep intronic mutation of c.1166-285 T > G in SLC46A1 is shared by four unrelated Japanese patients with hereditary folate malabsorption (HFM).

O. Ohara, M. Yamada, T. Ariga, 2019, Clinical immunology.

[Chemotherapy-induced diarrhea].

Kunihiko Kobayashi, K. Kobayashi, 2003, Gan to kagaku ryoho. Cancer & chemotherapy.

Extrarenal Nephroblastoma of the Retroperitoneal Space in Children: A Case Report and Review of the Literature.

Kunihiko Kobayashi, D. Suzuki, S. Fujita, 2017, Journal of pediatric hematology/oncology.

Lipoprotein profiles in children with two common cholesteryl ester transfer protein gene mutations, D442G and I14A, during the first year of life.

H. Tsukahara, Kunihiko Kobayashi, T. Miida, 2009, Clinica chimica acta; international journal of clinical chemistry.

Unique character and metabolism of high density lipoprotein (HDL) in fetus.

Kunihiko Kobayashi, H. Chiba, H. Yanai, 2002, Atherosclerosis.

Bevacizumab plus chemotherapy in nonsquamous non‐small cell lung cancer patients with malignant pleural effusion uncontrolled by tube drainage or pleurodesis: A phase II study North East Japan Study group trial NEJ013B

A. Gemma, M. Seike, K. Kubota, 2020, Thoracic cancer.

Associations between sex, age and spiritual well-being scores on the EORTC QLQ-SWB32 for patients receiving palliative care for cancer: A further analysis of data from an international validation study.

Kunihiko Kobayashi, G. Yang, N. Spry, 2019, European journal of cancer care.

A phase II study of carboplatin plus weekly paclitaxel with bevacizumab for elderly patients with non-squamous non-small-cell lung cancer (NEJ016)

A. Gemma, Kunihiko Kobayashi, T. Harada, 2017, Investigational New Drugs.

Successful treatment of congenital pulmonary alveolar proteinosis with intravenous immunoglobulin G administration

T. Ariga, Kunihiko Kobayashi, H. Minakami, 2006, Respirology.

Illness perceptions and quality of life in Japanese and Dutch patients with non-small-cell lung cancer.

W. A. van der Kloot, K. Rabe, N. Aaronson, 2011, Lung cancer.

Cross-cultural validation of the Japanese Functional Assessment of Cancer Therapy-Anemia (FACT-An).

A. Yoshimura, S. Kudoh, Kunihiko Kobayashi, 2004, Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.

Quality of Life Research that Dr. Hayashi Promoted and Prospects for the Future Study

Kunihiko Kobayashi, A. Matsuda, K. Yamaoka, 2018 .

Altered myocardial flow reserve and endothelial function late after Kawasaki disease.

N. Tamaki, Kunihiko Kobayashi, C. Katoh, 2003, The Journal of pediatrics.

Dissociative stupor mimicking consciousness disorder in an advanced lung cancer patient.

T. Okano, Kunihiko Kobayashi, Y. Tada, 2012, Japanese journal of clinical oncology.

Pharmacokinetic evaluation of intrapleural perfusion with hyperthermic chemotherapy using cisplatin in patients with malignant pleural effusion.

Kunihiko Kobayashi, H. Nitanda, H. Ishida, 2017, Lung cancer.

Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 2

K. Kaga, Y. Okamoto, Kunihiko Kobayashi, 2006, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Influence of clinical parameters on quality of life during chemotherapy in patients with advanced non-small cell lung cancer: application of a general linear model.

M. Shibuya, K. Eguchi, Y. Ohashi, 2003, Japanese journal of clinical oncology.

The Long-Term Outcomes of Induction Chemoradiotherapy Followed by Surgery for Locally Advanced Non-Small Cell Lung Cancer

H. Uramoto, Kunihiko Kobayashi, Takuya Inoue, 2014, Case Reports in Oncology.

Summarizing the Fifteen Scales of the EORTC QLQ-C30 Questionnaire by Five Aggregate Scales with Two Underlying Dimensions: A Literature Review and an Empirical Study

W. A. van der Kloot, Kenichi Inoue, Kunihiko Kobayashi, 2014, Journal of psychosocial oncology.

Individually different "weights" of quality of life assessment in patients with advanced nonsmall-cell lung cancer.

M. Shibuya, K. Eguchi, M. Fukuoka, 2003, Journal of clinical epidemiology.

Phase II study of carboplatin–paclitaxel alone or with bevacizumab in advanced sarcomatoid carcinoma of the lung: HOT1201/NEJ024

H. Dosaka-akita, Kunihiko Kobayashi, T. Harada, 2022, International Journal of Clinical Oncology.

Effectiveness of a Self-Monitoring Quality of Life Intervention For Patients with Cancer Receiving Palliative Care: A Randomized Controlled Clinical Trial

T. Ohkubo, E. Matsushima, Kunihiko Kobayashi, 2019, Asian Pacific journal of cancer prevention : APJCP.

A phase II study of erlotinib monotherapy in pre-treated non-small cell lung cancer without EGFR gene mutation who have never/light smoking history: re-evaluation of EGFR gene status (NEJ006/TCOG0903).

A. Gemma, Y. Ishii, Kunihiko Kobayashi, 2014, Lung cancer.

Randomized phase III trial of S-1 plus cisplatin versus docetaxel plus cisplatin for advanced non-small-cell lung cancer (TCOG0701).

A. Gemma, S. Kudoh, H. Ohmatsu, 2012 .

Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma: A Retrospective Analysis of 191 Patients from the NEJ023 Study.

K. Uematsu, S. Morita, Kazuhisa Takahashi, 2019, The oncologist.

CT Features of Epidermal Growth Factor Receptor–Mutated Adenocarcinoma of the Lung: Comparison with Nonmutated Adenocarcinoma

Kunihiko Kobayashi, F. Sakai, M. Hasegawa, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Randomized Phase III Trial of S-1 plus Cisplatin versus Docetaxel plus Cisplatin for Advanced Non-Small-Cell Lung Cancer TCOG 0701 CATS (Cisplatin And TS-1) Trial 1234

A. Gemma, S. Kudoh, M. Takeuchi, 2012 .

NEJ026: Final overall survival analysis of bevacizumab plus erlotinib treatment for NSCLC patients harboring activating EGFR-mutations.

A. Gemma, M. Okada, S. Morita, 2020 .

Induction of Necrotizing Funisitis by Fetal Administration of Intravenous Granulocyte-Colony Stimulating Factor and Intra-Amniotic Endotoxin in Premature Fetal Sheep

Kunihiko Kobayashi, Kazutoshi Cho, T. Matsuda, 2007, Pediatric Research.

Effects of a diphenyl ether-type herbicide, chlornitrofen, and its amino derivative on androgen and estrogen receptor activities.

Yoshihiro Hori, Eiji Katsura, Kunihiko Kobayashi, 2003, Environmental health perspectives.

Reliability of the peptide nucleic acid‐locked nucleic acid polymerase chain reaction clamp‐based test for epidermal growth factor receptor mutations integrated into the clinical practice for non‐small cell lung cancers

Tomoaki Tanaka, Kunihiko Kobayashi, M. Kanazawa, 2007, Cancer science.

E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib.

A. Yoshimura, A. Gemma, T. Okano, 2008, Oncology reports.

Single-Cell Analysis Reveals a CD4+ T-cell Cluster That Correlates with PD-1 Blockade Efficacy

T. Shibata, K. Horimoto, Y. Kanai, 2022, Cancer research.

Kunihiko Kobayashi, K. Yamaoka, F. Hayashi, 2003 .

Identification of adverse events that have a negative impact on quality of life in a clinical trial comparing docetaxel versus S-1 with cisplatin in lung cancer

A. Gemma, T. Takebayashi, M. Takeuchi, 2016, International Journal of Clinical Oncology.

Osimertinib versus osimertinib plus chemotherapy for non-small cell lung cancer with EGFR (T790M)-associated resistance to initial EGFR inhibitor treatment: An open-label, randomised phase 2 clinical trial.

K. Sugio, Kunihiko Kobayashi, S. Oizumi, 2021, European journal of cancer.

Effectiveness of EGFR‐TKI rechallenge immediately after PD‐1 blockade failure

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2021, Thoracic cancer.

Validation of the care notebook for measuring physical, mental and life well-being of patients with cancer

S. Kudoh, C. Gotay, Kunihiko Kobayashi, 2005, Quality of Life Research.

WEEKLY ASSESSMENT OF QUALITY OF LIFE IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG CANCER DURING CHEMOTHERAPY IN A RANDOMIZED PHASE III TRIAL

M. Shibuya, K. Eguchi, Y. Ohashi, 2004 .

Peptide nucleic acid–locked nucleic acid polymerase chain reaction clamp‐based detection test for gefitinib‐refractory T790M epidermal growth factor receptor mutation

Tomoaki Tanaka, S. Takenoshita, Kunihiko Kobayashi, 2008, Cancer science.

Precursor-T Lymphoblastic Lymphoma After Unrelated Bone Marrow Transplantation in a Patient With Fanconi Anemia

Kunihiko Kobayashi, D. Suzuki, A. Nakagawa, 2011, Journal of pediatric hematology/oncology.

We're in this together: Patients', caregivers' and health care providers' illness perceptions about non-small-cell lung cancer (NSCLC).

Kenichi Inoue, K. Kubota, Kunihiko Kobayashi, 2015, Lung cancer.

The effects of illness beliefs and chemotherapy impact on quality of life in Japanese and Dutch patients with breast or lung cancer.

W. A. van der Kloot, Kenichi Inoue, Kunihiko Kobayashi, 2016, Chinese clinical oncology.

Pretransplant paranasal sinus disease is associated with a high incidence of transplant‐related mortality in hematopoietic stem cell transplantation for children and adolescents

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2016, Pediatric transplantation.

Snake coiled fibres in rat soleus muscle in chloroquine induced myopathy share immunohistochemical characteristics with amyloid depositions in Alzheimer's disease brain tissue

Kunihiko Kobayashi, N. Fujii, R. Fukatsu, 1997, International journal of experimental pathology.

Detection of multiple druggable mutations of lung cancer from cytology specimens by MINtS: An advanced medicine A trial

N. Sunaga, Kunihiko Kobayashi, Satoshi Watanabe, 2023, Cancer science.

Paranasal sinusitis at the initiation of chemotherapy is a risk factor for invasive fungal disease in children and adolescents with cancer

Kunihiko Kobayashi, D. Suzuki, M. Yanagi, 2021, Supportive Care in Cancer.

Improvements of hypertriglyceridemia and hyperlacticemia in Japanese children with glycogen storage disease type Ia by medium-chain triglyceride milk

Kunihiko Kobayashi, T. Miida, A. Ohtake, 2007, European Journal of Pediatrics.

Central nervous system manifestations after steroid pulse therapy in systemic lupus erythematosus

I. Kobayashi, Kunihiko Kobayashi, M. Okano, 2002, European Journal of Pediatrics.

Effects of anti‐emetic drug (tropisetron) on quality of life during chemotherapy: Use of a diary‐type questionnaire and application of summary measures for assessment in a randomized, multicentre study

Kunihiko Kobayashi, H. Furue, H. Niitani, 1999, Respirology.

Comparison of Gefitinib Versus Chemotherapy in Patients with Non-small Cell Lung Cancer with Exon 19 Deletion.

Kunihiko Kobayashi, T. Nukiwa, Satoshi Watanabe, 2015, Anticancer research.

A randomized phase III trial of oral S-1 plus cisplatin versus docetaxel plus cisplatin in Japanese patients with advanced non-small-cell lung cancer: TCOG0701 CATS trial

A. Gemma, S. Kudoh, H. Ohmatsu, 2015, Annals of oncology : official journal of the European Society for Medical Oncology.

Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemo-naïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002).

A. Gemma, S. Morita, Kunihiko Kobayashi, 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

Alternating chemotherapy with amrubicin plus cisplatin and weekly administration of irinotecan plus cisplatin for extensive-stage small cell lung cancer.

A. Yoshimura, A. Gemma, T. Okano, 2013, Anticancer Research.

Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation

Kunihiko Kobayashi, K. Kaira, H. Kagamu, 2019, Cancer Chemotherapy and Pharmacology.

Final overall survival results of NEJ002, a phase III trial comparing gefitinib to carboplatin (CBDCA) plus paclitaxel (TXL) as the first-line treatment for advanced non-small cell lung cancer (NSCLC) with EGFR mutations.

A. Gemma, Kunihiko Kobayashi, S. Oizumi, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Illness perceptions and quality of life in Japanese and Dutch patients with non-small-cell lung cancer.

W. A. van der Kloot, K. Rabe, N. Aaronson, 2011, Lung cancer.

Dual control of the brainstem on the spindle oscillation in humans

S. Kohsaka, Kunihiko Kobayashi, M. Kohsaka, 2000, Brain Research.

Clinicopathological impact of VEGFR2 and VEGF‐C in patients with EGFR ‐major mutant NSCLC receiving osimertinib

Kunihiko Kobayashi, T. Kawasaki, K. Kaira, 2023, Thoracic cancer.

First-line gefitinib versus first-line chemotherapy by carboplatin (CBDCA) plus paclitaxel (TXL) in non-small cell lung cancer (NSCLC) patients (pts) with EGFR mutations: A phase III study (002) by North East Japan Gefitinib Study Group.

A. Gemma, Kunihiko Kobayashi, S. Oizumi, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Risk factors for tumor lysis syndrome in childhood acute myeloid leukemia treated with a uniform protocol without rasburicase prophylaxis

Kunihiko Kobayashi, D. Suzuki, R. Kobayashi, 2015, Leukemia & lymphoma.