V. Khazak

发表

Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells

C. Der, A. Cox, V. González-Pérez, 2010, Journal of molecular signaling.

Selective Raf inhibition in cancer therapy

Erica A Golemis, Ilya G Serebriiskii, Vladimir Khazak, 2007, Expert opinion on therapeutic targets.

Solution phase parallel synthesis and evaluation of MAPK inhibitory activities of close structural analogues of a Ras pathway modulator.

Yingchun Lu, Lutz Weber, Vladimir Khazak, 2004, Bioorganic & medicinal chemistry letters.

Identical amino acid sequence of the aroA(G) gene products of Bacillus subtilis 168 and B. subtilis Marburg strain.

V. Khazak, A. Bolotin, N. Stoynova, 1995, Microbiology.

Redefinition of the yeast two-hybrid system in dialogue with changing priorities in biological research.

E. Golemis, V. Khazak, I. Serebriiskii, 2001, BioTechniques.

Isoquinolin‐1‐one Inhibitors of the MDM2–p53 Interaction

Cédric Kalinski, Marcin Krajewski, Lutz Weber, 2008, ChemMedChem.

Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3–MYC Interactions as a Target in Pancreatic Cancer

Yan Zhou, E. Golemis, L. Weiner, 2016, Clinical Cancer Research.

Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

S. Jhanwar, J. Testa, R. Flores, 2020, Clinical Cancer Research.

HSP90 Inhibitor–SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors

D. Proia, R. Bates, V. Khazak, 2015, Molecular Cancer Therapeutics.

A two-hybrid approach to identify inhibitors of the RAS-RAF interaction.

F. Tamanoi, E. Golemis, V. Khazak, 2013, The Enzymes.

Ras-driven transformation of human nestin-positive pancreatic epithelial cells.

P. M. Campbell, C. Der, Hong-Jin Kim, 2008, Methods in enzymology.

Context-dependent roles of mutant B-Raf signaling in melanoma and colorectal carcinoma cell growth

C. Der, J. M. Shields, V. Khazak, 2007, Molecular Cancer Therapeutics.

K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling.

P. M. Campbell, C. Der, M. Ouellette, 2007, Cancer research.

Phosphatidylinositol 3-Kinase Signaling Immortalized Human Pancreatic Cells by Raf and KRas Promotes Growth Transformation and Invasion of Updated

P. M. Campbell, C. Der, M. Ouellette, 2007 .

Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer.

R. Moffitt, E. Golemis, Yinfei Tan, 2020, Cancer cell.

Interactions between the Human RNA Polymerase II Subunits*

J. Acker, M. Vigneron, C. Kedinger, 1997, The Journal of Biological Chemistry.

Development of a Yeast Two-Hybrid Screen for Selection of Human Ras-Raf Protein Interaction Inhibitors

L. Weber, E. Golemis, V. Khazak, 2005, Methods in molecular biology.

Detection of peptides, proteins, and drugs that selectively interact with protein targets.

Jonathan Chernoff, Erica A Golemis, Ilya G Serebriiskii, 2002, Genome research.

A Two-hybrid Dual Bait System to Discriminate Specificity of Protein Interactions*

E. Golemis, V. Khazak, I. Serebriiskii, 1999, The Journal of Biological Chemistry.

A Novel HSP90 Inhibitor–Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer

James S. Duncan, A. Gaponova, A. Nikonova, 2016, Clinical Cancer Research.

Analysis of the Interaction of the Novel RNA Polymerase II (pol II) Subunit hsRPB4 with Its Partner hsRPB7 and with pol II

Erica A. Golemis, Vladimir Khazak, J. Testa, 1998, Molecular and Cellular Biology.

Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology.

D. Botstein, R. Brent, E. Golemis, 1995, Molecular biology of the cell.

Screening of Conditionally Reprogrammed Patient-Derived Carcinoma Cells Identifies ERCC3-MYC Interactions as a Target in Pancreatic Cancer.

Yan Zhou, E. Golemis, L. Weiner, 2016, Clinical cancer research : an official journal of the American Association for Cancer Research.

Alternative yeast two-hybrid systems. The interaction trap and interaction mating.

E. Golemis, V. Khazak, E A Golemis, 1997, Methods in molecular biology.

Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells

Jie Zhang, Yingchun Lu, Gang Zhi, 2002, Proceedings of the National Academy of Sciences of the United States of America.

CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma

R. Uzzo, Y. Boumber, V. Khazak, 2020, British Journal of Cancer.

Ligand-free RAR can interact with the RNA polymerase II subunit hsRPB7 and repress transcription

E. Golemis, V. Khazak, L. Shemshedini, 1999, Endocrine.

Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II

Erica A Golemis, Vladimir Khazak, E. Golemis, 1998, Oncogene.

Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms

W. El-Deiry, Lanlan Zhou, C. L. Kline, 2018, Journal of Experimental & Clinical Cancer Research.

In vitro and in vivo synergy of MCP compounds with mitogen-activated protein kinase pathway– and microtubule-targeting inhibitors

L. Weber, E. Golemis, S. Menon, 2007, Molecular Cancer Therapeutics.

247 Assessment of sensitivity to a PD-1 check point inhibitor and cisplatin in bladder cancer patient-derived xenografts with various levels of PD-L1 expression in HuCD34NCG mice

V. Khazak, S. Festin, B. K. Jones, 2020, Journal for ImmunoTherapy of Cancer.

Re-purposing clinical kinase inhibitors to enhance chemosensitivity by overriding checkpoints

S. Deacon, J. R. Peterson, B. Egleston, 2014, Cell cycle.

Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms

W. El-Deiry, Lanlan Zhou, C. L. Kline, 2018, Journal of experimental & clinical cancer research : CR.

Targeted delivery of chemotherapy using HSP90 inhibitor drug conjugates is highly active against pancreatic cancer models

D. Proia, E. Golemis, V. Khazak, 2016, Oncotarget.

Yeast screens for inhibitors of Ras-Raf interaction and characterization of MCP inhibitors of Ras-Raf interaction.

F. Tamanoi, E. Golemis, V. Khazak, 2006, Methods in enzymology.