Y. Jacquot

发表

High affinity Grb2-SH3 domain ligand incorporating Cbeta-substituted prolines in a Sos-derived decapeptide.

M. Desmadril, Y. Jacquot, I. Broutin, 2007, Bioorganic & medicinal chemistry.

Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells.

G. Leclercq, Y. Jacquot, G. Laurent, 2007, Bioorganic & medicinal chemistry.

ERα dimerization: a key factor for the weak estrogenic activity of an ERα modulator unable to compete with estradiol in binding assays

E. Lesniewska, G. Leclercq, D. Leiber, 2017, Journal of receptor and signal transduction research.

Stabilisation of a short α‐helical VIP fragment by side chain to side chain cyclisation: a comparison of common cyclisation motifs by circular dichroism

Y. Jacquot, D. Tourwé, Lukasz P. Frankiewicz, 2013, Journal of peptide science : an official publication of the European Peptide Society.

A critical view of the effects of phytoestrogens on hot flashes and breast cancer risk.

G. Leclercq, P. de Cremoux, Y. Jacquot, 2011, Maturitas.

ERE‐dependent transcription and cell proliferation: Independency of these two processes mediated by the introduction of a sulfone function into the weak estrogen estrothiazine

S. Rudaz, E. Lesniewska, G. Leclercq, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Electronic circular dichroism and nuclear magnetic resonance studies of peptides derived from the FKBP52‐interacting β‐turn of the hERα ligand‐binding domain

E. Baulieu, Y. Jacquot, O. Lequin, 2019, Peptide Science.

Computational Approaches for the Discovery of GPER Targeting Compounds

Y. Jacquot, F. Cirillo, M. Maggiolini, 2020, Frontiers in Endocrinology.

Whole transcriptome analysis of the ERα synthetic fragment P295‐T311 (ERα17p) identifies specific ERα‐isoform (ERα, ERα36)‐dependent and ‐independent actions in breast cancer cells

M. Kampa, E. Castanas, G. Leclercq, 2013, Molecular oncology.

ERα17p, an ERα P295‐T311 fragment, modifies the migration of breast cancer cells, through actin cytoskeleton rearrangements

M. Kampa, E. Castanas, G. Leclercq, 2011, Journal of cellular biochemistry.

The sequence Pro295-Thr311 of the hinge region of oestrogen receptor α is involved in ERK1/2 activation via GPR30 in leiomyoma cells.

G. Leclercq, P. Robin, D. Leiber, 2015, The Biochemical journal.

Trophic effect in MCF-7 cells of ERα17p, a peptide corresponding to a platform regulatory motif of the estrogen receptor α—Underlying mechanisms

G. Leclercq, Y. Jacquot, G. Laurent, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

Isomerization and Oligomerization of Truncated and Mutated Tau Forms by FKBP52 are Independent Processes.

I. Landrieu, G. Lippens, E. Baulieu, 2016, Journal of molecular biology.

Interactions of isoflavones and other plant derived estrogens with estrogen receptors for prevention and treatment of breast cancer—Considerations concerning related efficacy and safety

G. Leclercq, Y. Jacquot, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Lack of sufficient information on the specificity and selectivity of commercial phytoestrogens preparations for therapeutic purposes.

G. Leclercq, P. de Cremoux, Y. Jacquot, 2011, Maturitas.

Controversies concerning the use of phytoestrogens in menopause management: bioavailability and metabolism.

G. Leclercq, P. de Cremoux, Y. Jacquot, 2010, Maturitas.

Improvement of the anti-proliferative activity of the peptide ERα17p in MCF-7 breast cancer cells using nanodiamonds.

Y. Jacquot, C. Mansuy, D. Decaudin, 2019, Annales pharmaceutiques francaises.

Analysis of the progesterone displacement of its human serum albumin binding site by beta-estradiol using biochromatographic approaches: effect of two salt modifiers.

Y. Guillaume, Y. Jacquot, C. André, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Synthesis, structure, and estrogenic activity of 2- and 3-substituted 2,3-dihydro-4H-1-benzopyran-4-ones

G. Leclercq, Y. Jacquot, A. Xicluna, 2013, Medicinal Chemistry Research.

Calmodulin, a regulatory partner of the estrogen receptor alpha in breast cancer cells

G. Leclercq, Y. Jacquot, G. Laurent, 2008, Molecular and Cellular Endocrinology.

Bio-inspired hybrid fluorescent ligands for the FK1 domain of FKBP52.

E. Baulieu, H. van Tilbeurgh, M. Aumont-Nicaise, 2020, Journal of medicinal chemistry.

Synthesis of 4-hydroxycoumarin and 2,4-quinolinediol derivatives and evaluation of their effects on the viability of HepG2 cells and human hepatocytes culture.

Y. Jacquot, G. Mantion, B. Refouvelet, 2004, European journal of medicinal chemistry.

Recent advances in the development of phytoestrogens and derivatives: an update of the promising perspectives in the prevention of postmenopausal diseases.

Y. Jacquot, G. Leclercq, B. Refouvelet, 2003, Mini reviews in medicinal chemistry.

Pharmacological profile of 6,12-dihydro-3-methoxy-1-benzopyrano[3,4-b] [1,4]benzothiazin-6-one, a novel human estrogen receptor agonist.

G. Leclercq, Y. Jacquot, G. Adessi, 2002, Biological & pharmaceutical bulletin.

Substituted benzopyranobenzothiazinones. Synthesis and estrogenic activity on MCF-7 breast carcinoma cells.

Y. Jacquot, G. Adessi, L. Bermont, 2001, European journal of medicinal chemistry.

A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.

Morkos A. Henen, I. Landrieu, G. Lippens, 2016, Biochemistry.

Stereochemical effects during [M-H]− dissociations of epimeric 11-OH-17β-estradiols and distant electronic effects of substituents at C(11) position on gas phase acidity

G. Leclercq, Y. Jacquot, J. Tabet, 2009, Journal of the American Society for Mass Spectrometry.

Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha

P. Brown, G. Leclercq, Y. Jacquot, 2006, Breast Cancer Research and Treatment.

Peptides targeting estrogen receptor alpha-potential applications for breast cancer treatment.

Janine Cossy, Guy Leclercq, Denis Larsimont, 2011, Current pharmaceutical design.

Electronic Effects of 11β Substituted 17β-Estradiol Derivatives and Instrumental Effects on the Relative Gas Phase Acidity

G. Leclercq, Y. Jacquot, J. Tabet, 2012, Journal of The American Society for Mass Spectrometry.

Identification of a human estrogen receptor α tetrapeptidic fragment with dual antiproliferative and anti-nociceptive action

A. Eschalier, Y. Jacquot, M. Maggiolini, 2023, Scientific Reports.

Identification of a human estrogen receptor α‐derived antiestrogenic peptide that adopts a polyproline II conformation

G. Leclercq, M. Desmadril, Y. Jacquot, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Supplementary Materials for Identification of the Tau phosphorylation pattern that drives its aggregation

I. Landrieu, G. Lippens, E. Baulieu, 2017 .

GPCR Modulation in Breast Cancer

Y. Jacquot, M. Maggiolini, R. Lappano, 2018, International journal of molecular sciences.

Asymmetric synthesis of 3-substituted proline chimeras bearing polar side chains of proteinogenic amino acids.

Y. Jacquot, P. Karoyan, S. Lavielle, 2004, The Journal of organic chemistry.

Concentration‐dependent and surface‐assisted self‐assembly properties of a bioactive estrogen receptor α‐derived peptide

Y. Jacquot, G. Dietler, G. Ducouret, 2015, Journal of peptide science : an official publication of the European Peptide Society.

Editorial: GPER: Control and Functions

M. Kampa, Y. Jacquot, S. Lindsey, 2021, Frontiers in Endocrinology.

Editorial: GPER and Human Pathologies

M. Kampa, Y. Jacquot, S. Lindsey, 2021, Frontiers in Endocrinology.

Capacity of type I and II ligands to confer to estrogen receptor alpha an appropriate conformation for the recruitment of coactivators containing a LxxLL motif-Relationship with the regulation of receptor level and ERE-dependent transcription in MCF-7 cells.

G. Leclercq, Y. Jacquot, G. Laurent, 2010, Biochemical pharmacology.

The Antitumor Peptide ERα17p Exerts Anti-Hyperalgesic and Anti-Inflammatory Actions Through GPER in Mice

A. Eschalier, Y. Jacquot, C. Mallet, 2021, Frontiers in Endocrinology.

Deciphering of a Putative GPER Recognition Domain in ERα and ERα36

Y. Jacquot, A. Acramel, Alexandre Acramel, 2022, Frontiers in Endocrinology.

Regulatory function of the P295-T311 motif of the estrogen receptor α - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses?

G. Leclercq, Y. Jacquot, G. Laurent, 2008, Nuclear receptor signaling.

The estrogen receptor alpha‐derived peptide ERα17p (P295‐T311) exerts pro‐apoptotic actions in breast cancer cells in vitro and in vivo, independently from their ERα status

Guy Leclercq, George Notas, M. Kampa, 2011, Molecular oncology.

In-source fragmentation of very labile peptides in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Y. Jacquot, G. Bolbach, T. Blasco, 2009, Analytical chemistry.

A Phosphorylation-Induced Turn Defines the Alzheimer's Disease AT8 Antibody Epitope on the Tau Protein.

Neha S. Gandhi, I. Landrieu, J. Wieruszeski, 2015, Angewandte Chemie.

Identification of polyproline II regions derived from the proline-rich nuclear receptor coactivators PNRC and PNRC2: new insights for ERα coactivator interactions.

V. Pelekanou, E. Castanas, G. Leclercq, 2013, Chirality.

Calmodulin-independent, agonistic properties of a peptide containing the calmodulin binding site of estrogen receptor α

G. Leclercq, Y. Jacquot, G. Laurent, 2007, Molecular and Cellular Endocrinology.

Synthesis, structure, and estrogenic activity of 2- and 3-substituted 2,3-dihydro-4H-1-benzopyran-4-ones

G. Leclercq, Y. Jacquot, A. Xicluna, 2013, Medicinal Chemistry Research.

Biophysical studies of the interaction between calmodulin and the R²⁸⁷-T³¹¹ region of human estrogen receptor α reveals an atypical binding process.

G. Leclercq, M. Desmadril, L. Carlier, 2012, Biochemical and biophysical research communications.

Biophysical studies of the interaction between calmodulin and the R 287-T 311 region of human estrogen receptor a reveals an atypical binding process

G. Leclercq, M. Desmadril, L. Carlier, 2012 .

ERα17p, a peptide reproducing the hinge region of the estrogen receptor α associates to biological membranes: A biophysical approach

M. Kampa, E. Castanas, G. Leclercq, 2012, Steroids.

Calmodulin association with the synthetic ERα17p peptide investigated by mass spectrometry

G. Leclercq, Y. Jacquot, J. Tabet, 2011 .

The Peptide ERα17p Is a GPER Inverse Agonist that Exerts Antiproliferative Effects in Breast Cancer Cells

A. Eschalier, Y. Jacquot, I. Broutin, 2019, Cells.

Application of Circular Dichroism Spectroscopy to the Analysis of the Interaction Between the Estrogen Receptor Alpha and Coactivators: The Case of Calmodulin.

Y. Jacquot, E. Miclet, C. Byrne, 2016, Methods in molecular biology.

Promising Perspectives of the Antiproliferative GPER Inverse Agonist ERα17p in Breast Cancer

M. Kampa, E. Castanas, Y. Jacquot, 2023, Cells.

Interaction of the Anti-Proliferative GPER Inverse Agonist ERα17p with the Breast Cancer Cell Plasma Membrane: From Biophysics to Biology

I. Alves, S. Sagan, Y. Jacquot, 2020, Cells.

Molecular Basis of Agonistic Activity of ERα17p, a Synthetic Peptide Corresponding to a Sequence Located at the N-Terminal Part of the Estrogen Receptor αLigand Binding Domain

G. Leclercq, Y. Jacquot, G. Laurent, 2007 .

Estrogen receptor alpha—Identification by a modeling approach of a potential polyproline II recognizing domain within the AF-2 region of the receptor that would play a role of prime importance in its mechanism of action

G. Leclercq, Y. Jacquot, D. Gallo, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Inviting C5-Trifluoromethylated Pseudoprolines into Collagen Mimetic Peptides.

R. Marquant, Y. Jacquot, E. Miclet, 2023, Biomacromolecules.

Structure elucidation of benzopyran-2-ol in solution and in solid state following the reduction of coumarin by DIBAL-H

Y. Jacquot, O. Blacque, B. Refouvelet, 2001 .

ERα17p, an ERα P295‐T311 fragment, modifies the migration of breast cancer cells, through actin cytoskeleton rearrangements

M. Kampa, E. Castanas, G. Leclercq, 2011, Journal of cellular biochemistry.

Stereochemical Dissociations of Epimeric 11-OH-17 (cid:3) -Estradiols and Distant Electronic Effects of Substituents at C (11) Position on Gas Phase Acidity

Y. Jacquot, S. Bourgoin-Voillard, E. Zins, 2011 .