N. Aoyama

发表

BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms

M. Kasuga, N. Ikehara, S. Semba, 2005, International journal of cancer.

Association of VEGF genotype with mRNA level in colorectal adenocarcinomas.

M. Kasuga, A. Gotoh, T. Shirakawa, 2004, Biochemical and biophysical research communications.

Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors.

M. Kasuga, N. Aoyama, T. Sakaeda, 2003, Biological & pharmaceutical bulletin.

Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

T. Hirayama, T. Shintani, M. Noda, 2003, Nature Genetics.

Recurrent Peptic Ulcers in Patients Following Successful Helicobacter pylori Eradication: A Multicenter Study of 4940 Patients

K. Sugano, T. Ohkusa, K. Haruma, 2004, Helicobacter.

SUPERFICIALLY ELEVATED‐TYPE SERRATED HYPERPLASTIC LESION OF THE STOMACH WITH MINUTE ADENOCARCINOMA

S. Semba, N. Aoyama, H. Yokozaki, 2009, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Observation of gastro-esophageal reflux by MRI: a feasibility study

K. Sugimura, T. Higashino, H. Kawamitsu, 2009, Abdominal Imaging.

Diagnostic significance of gently sloping depression and irregular margin in superficial elevated colorectal tumors

M. Kasuga, N. Aoyama, Y. Morita, 2006, International Journal of Colorectal Disease.

Flat-elevated and depressed, subtypes of flat early colorectal cancers, should be distinguished by their pathological features

R. Minami, M. Kasuga, M. Sakashita, 2000, International Journal of Colorectal Disease.

Circadian Variability of Pharmacokinetics of 5-Fluorouracil and CLOCK T3111C Genetic Polymorphism in Patients With Esophageal Carcinoma

M. Kasuga, N. Aoyama, T. Sakaeda, 2005, Therapeutic drug monitoring.

Prospect of Endoscopic Mucosal Resection for Early Gastric Cancer: Our Devices in Insulated‐Tip Electrosurgical Knife Method

M. Kasuga, N. Aoyama, Y. Morita, 2003 .

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects

M. Kasuga, T. Shirakawa, M. Matsuo, 2002, Clinical pharmacology and therapeutics.

HLA‐DQB1 locus and gastric cancer in Helicobacter pylori infection

M. Kasuga, N. Aoyama, T. Tamura, 2006, Journal of gastroenterology and hepatology.

Kobe University Repository : Kernel タイトル Tit le MDR 1 , MRP 1 and MRP 2 Genotypes and In Vit ro Chemosensit ivity in Japanese Pat ients with Colorectal Adenocarcinomas 著者

M. Kasuga, N. Aoyama, T. Sakaeda, 2018 .

MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.

M. Kasuga, N. Aoyama, T. Sakaeda, 2004, The Kobe journal of medical sciences.

HLA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression

M. Kasuga, N. Aoyama, T. Naruse, 1995, Digestive Diseases and Sciences.

Excessive alcohol intake enhances the development of synchronous cancerous lesion in colorectal cancer patients

M. Kasuga, N. Aoyama, T. Tamura, 2004, International Journal of Colorectal Disease.

Role of metallothionein in Helicobacter pylori‐positive gastric mucosa with or without early gastric cancer and the effect on its expression after eradication therapy

M. Kasuga, Y. Matsumoto, T. Azuma, 2008, Journal of gastroenterology and hepatology.

Cell kinetic balance in gastric mucosa with intestinal metaplasia after Helicobacter pylori eradication: 2-year follow-up study.

M. Kasuga, N. Aoyama, T. Tamura, 2004, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

MDR1 Genotype-Related Duodenal Absorption Rate of Digoxin in Healthy Japanese Subjects

M. Kasuga, N. Aoyama, T. Sakaeda, 2003, Pharmaceutical Research.

Effects of polymorphisms of MDR1, MRP1, and MRP2 genes on their mRNA expression levels in duodenal enterocytes of healthy Japanese subjects.

M. Kasuga, A. Gotoh, T. Shirakawa, 2002, Biological & pharmaceutical bulletin.

VEGF T-1498C polymorphism, a predictive marker of differentiation of colorectal adenocarcinomas in Japanese

M. Kasuga, S. Markova, A. Kuwahara, 2008, International journal of medical sciences.

Impact of clarithromycin resistance and CYP2C19 genetic polymorphism on treatment efficacy of Helicobacter pylori infection with lansoprazole- or rabeprazole-based triple therapy in Japan

M. Kasuga, N. Aoyama, T. Sakaeda, 2003, European journal of gastroenterology & hepatology.

Exploratory Study of the Effectiveness of Granulocyte and Monocyte Adsorptive Apheresis Before Initiation of Steroids in Patients With Active Ulcerative Colitis (EXPECT Study): A Multicenter Prospective Clinical Trial

K. Higuchi, N. Aoyama, N. Kamata, 2020, Crohn's & colitis 360.

An Open-Label Prospective Randomized Multicenter Study Shows Very Rapid Remission of Ulcerative Colitis by Intensive Granulocyte and Monocyte Adsorptive Apheresis as Compared With Routine Weekly Treatment

T. Matsui, T. Hibi, N. Aoyama, 2009, The American Journal of Gastroenterology.

MDR1 T-129C polymorphism can be predictive of differentiation, and thereby prognosis of colorectal adenocarcinomas in Japanese.

M. Kasuga, T. Koyama, N. Aoyama, 2006, Biological & pharmaceutical bulletin.

Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells.

M. Kasuga, H. Saya, R. Takahashi, 1995, Oncogene.

Abstracts of selected papers presented at the 79th general meeting of the Japanese Society of Gastroenterology March 29–31, 1993, Kyoto, Japan

H. Sugimoto, H. Okano, Y. Yamada, 1991, Gastroenterologia Japonica.

Severe insulin-resistant diabetes mellitus associated with hypereosinophilic syndrome.

K. Amano, M. Kasuga, N. Aoyama, 1994, Internal medicine.

Significant Genetic Linkage of MDR1 Polymorphisms at Positions 3435 and 2677: Functional Relevance to Pharmacokinetics of Digoxin

M. Kasuga, N. Aoyama, T. Sakaeda, 2002, Pharmaceutical Research.

Analysis of Helicobacter pylori vacA Gene and Serum Antibodies to VacA in Japan

T. Hirayama, M. Kasuga, M. Sakashita, 2000, Digestive Diseases and Sciences.

Relationship Between Gastric Ulcer and Helicobacter pylori VacA Detected in Gastric Juice Using Bead‐ELISA Method

T. Hirayama, M. Kasuga, M. Sakashita, 2002, Helicobacter.

CYP2C19 Genotype Related Effect of Omeprazole on Intragastric pH and Antimicrobial Stability

M. Kasuga, Y. Tanigawara, N. Aoyama, 2001, Pharmaceutical Research.

Efficacy of Granulocyte and Monocyte Adsorptive Apheresis in Patients with Inflammatory Bowel Disease Showing Lost Response to Infliximab.

N. Aoyama, N. Yoshimura, Yasuo Suzuki, 2020, Journal of Crohn's & colitis.

Middle-term prognosis in patients with ulcerative colitis who achieved clinical and endoscopic remission by budesonide rectal foam

T. Kanai, Mamoru Watanabe, N. Aoyama, 2019, PloS one.

Complete mucosal healing of distal lesions induced by twice-daily budesonide 2-mg foam promoted clinical remission of mild-to-moderate ulcerative colitis with distal active inflammation: double-blind, randomized study

T. Hibi, Mamoru Watanabe, N. Aoyama, 2017, Journal of Gastroenterology.

Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis.

M. Kasuga, T. Fujimori, H. Kawamata, 2003, Journal of experimental & clinical cancer research : CR.

Comparison of synthetic DNA templates with authentic cDNA templates in terms of quantification by real-time quantitative reverse transcription polymerase chain reaction.

M. Kasuga, N. Aoyama, T. Sakaeda, 2006, Biological & pharmaceutical bulletin.

Effect of trimebutine maleate on emptying of stomach and gallbladder and release of gut peptide following a solid meal in man

M. Kasuga, A. Inui, N. Aoyama, 1993, Digestive Diseases and Sciences.

EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion

M. Kasuga, A. Inui, N. Aoyama, 1996, Peptides.

Safety and effectiveness of granulocyte and monocyte adsorptive apheresis in patients with inflammatory bowel disease in special situations: a multicentre cohort study

M. Nojima, N. Aoyama, T. Osada, 2019, BMC Gastroenterology.

Twice-daily Budesonide 2-mg Foam Induces Complete Mucosal Healing in Patients with Distal Ulcerative Colitis

T. Hibi, N. Aoyama, Kiyonori Kobayashi, 2015, Journal of Crohn's & colitis.

A multicenter study of the efficacy and safety of leukocytapheresis therapy without concomitant systemic steroid treatment in patients with active ulcerative colitis.

A. Munakata, T. Matsui, T. Hibi, 2011, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

Leukocytapheresis therapy for steroid‐naïve patients with active ulcerative colitis: Its clinical efficacy and adverse effects compared with those of conventional steroid therapy

M. Kasuga, N. Aoyama, T. Abe, 2005, Journal of gastroenterology and hepatology.

Colon Polyps Detected by Contrast Chromoscopy Using Indigo Carmine Capsule

S. Maeda, T. Fujimori, N. Aoyama, 1992 .

Chemosensitivity Assessed by Collagen Gel Droplet Embedded Culture Drug Sensitivity Test, and MDR1, MRP1, and MRP2 mRNA Expression in Human Colorectal Adenocarcinomas

M. Kasuga, A. Gotoh, T. Shirakawa, 2004, Pharmaceutical Research.

Peptic Ulcers After the Hanshin-Awaji Earthquake: Increased Incidence of Bleeding Gastric Ulcers

M. Kasuga, T. Chiba, N. Aoyama, 1998, American Journal of Gastroenterology.

Development of a C1q-immobilized (Cim) assay to measure total antibodies to infliximab and its clinical relevance in patients with inflammatory bowel disease.

N. Aoyama, N. Yoshimura, Yasuo Suzuki, 2019, Cytokine.

Helicobacter pylori eradication and metachronous gastric cancer after endoscopic mucosal resection of early gastric cancer

M. Tatsuta, H. Goto, T. Fujioka, 2006 .

Argon plasma coagulation for treatment of hemorrhagic radiation gastroduodenitis

M. Kasuga, N. Aoyama, T. Tamura, 2002 .

Prevention of Irinotecan-Induced Diarrhea by Oral Sodium Bicarbonate and Influence on Pharmacokinetics

M. Kasuga, H. Nishisaki, N. Aoyama, 2005, Oncology.

CYP2C19 genotype–related efficacy of omeprazole for the treatment of infection caused by Helicobacter pylori

Y. Tanigawara, N. Aoyama, F. Komada, 1999 .

Interaction of Docetaxel (“Taxotere”) with Human P‐Glycoprotein

M. Kasuga, Y. Tanigawara, N. Aoyama, 1999, Japanese journal of cancer research : Gann.

Impact of Helicobacter pylori Eradication Therapy on Histologic Change in the Distal Esophagus

M. Kasuga, Y. Matsumoto, N. Aoyama, 2006, Helicobacter.

Codon 201Arg/Gly Polymorphism of DCC (Deleted in Colorectal Carcinoma) Gene in Flat- and Polypoid-Type Colorectal Tumors

R. Minami, S. Maeda, M. Kasuga, 1997, Digestive Diseases and Sciences.

Variation in MT expression in early-stage depressed-type and polypoid-type colorectal tumours.

R. Minami, M. Kasuga, M. Sakashita, 2002, European journal of cancer.

Primary Levofloxacin Resistance and gyrA/B Mutations Among Helicobacter pylori in Japan

M. Kasuga, Y. Matsumoto, N. Aoyama, 2006, Helicobacter.

A CASE OF PRIMARY DUODENAL CANCER OF ULCERATING TYPE IN THE INFRAPAPILLARY REGION

A. Inui, N. Aoyama, G. Yoshino, 1989 .

Endoscopic retrograde biliary drainage for posttraumatic intrapancreatic biliary stenosis in a child.

N. Aoyama, S. Takamizawa, E. Nishijima, 2009, Journal of pediatric surgery.

MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects

Yoshinori Morita, Masato Kasuga, Takao Tamura, 2001, Pharmaceutical Research.

Gastric Ulcer Formation after the Hanshin‐Awaji Earthquake: A Case Study of Helicobacter pylori Infection and Stress‐Induced Gastric Ulcers

N. Aoyama, Y. Kinoshita, H. Nakase, 1999, Helicobacter.

Assessment of microsatellite instability status for the prediction of metachronous recurrence after initial endoscopic submucosal dissection for early gastric cancer

S. Semba, N. Aoyama, H. Yokozaki, 2006, British Journal of Cancer.

Evaluation of Gastric Ulcer Healing by Lansoprazole by Measurement of Ulcer Diameter

N. Aoyama, Y. Kinoshita, Tsutomu Chiba, 1995, Journal of Clinical Gastroenterology.

Comparison of efficacy of multimatrix mesalazine 4.8 g/day once-daily with other high-dose mesalazine in active ulcerative colitis: a randomized, double-blind study

H. Ogata, T. Hibi, N. Aoyama, 2017, Intestinal research.

MDR1 haplotype frequencies in Japanese and Caucasian, and in Japanese patients with colorectal cancer and esophageal cancer.

M. Kasuga, D. Kroetz, T. Koyama, 2006, Drug metabolism and pharmacokinetics.

Metastatic lobular carcinoma of the breast masquerading as a primary rectal cancer

N. Matsubara, H. Ikeuchi, T. Yamano, 2012, World Journal of Surgical Oncology.

Helicobacter pylori-negative peptic ulcer in Japan: which contributes most to peptic ulcer development, Helicobacter pylori, NSAIDS or stress?

M. Kasuga, T. Chiba, N. Aoyama, 2000, Journal of gastroenterology.

Levofloxacin- versus metronidazole-based rescue therapy for H. pylori infection in Japan.

M. Kasuga, Y. Matsumoto, Y. Morita, 2005, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Glut1 expression in T1 and T2 stage colorectal carcinomas: its relationship to clinicopathological features.

R. Minami, M. Kasuga, M. Sakashita, 2001, European journal of cancer.

Upadacitinib Induction and Maintenance Therapy Improves Abdominal Pain, Bowel Urgency, and Fatigue in Patients With Ulcerative Colitis: A Post Hoc Analysis of Phase 3 Data.

G. D'Haens, N. Aoyama, R. Panaccione, 2023, Inflammatory bowel diseases.

Approach to the Seamless Management of Inflammatory Bowel Disease, Considering Special Situations, Shared Decision-Making, and Disease Burden

N. Aoyama, Toshiaki Shimizu, 2020, Digestion.

N03 Disease burden of patients with inflammatory bowel disease from the viewpoint of QOL and depression

N. Aoyama, M. Nunotani, M. Takahashi, 2020 .

Abstracts of selected papers presented at the 78th general meeting of the Japanese Society of Gastroenterology

Y. Hatada, M. Hashizume, T. Suzuki, 1993, Gastroenterologia Japonica.

MDR1 C3435T polymorphism is predictive of later onset of ulcerative colitis in Japanese.

M. Kasuga, T. Koyama, N. Aoyama, 2006, Biological & pharmaceutical bulletin.

Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.

M. Kasuga, T. Shirakawa, M. Matsuo, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Relationship of BRAF mutation, morphology, and apoptosis in early colorectal cancer

M. Kasuga, T. Azuma, N. Ikehara, 2007, International Journal of Colorectal Disease.

Rabeprazole‐based eradication therapy for Helicobacter pylori: a large‐scale study in Japan

T. Fujioka, M. Asaka, T. Sugiyama, 2007, Alimentary pharmacology & therapeutics.

Influence of gastritis on cyclooxygenase-2 expression before and after eradication of Helicobacter pylori infection

M. Kasuga, N. Aoyama, T. Tamura, 2004, European journal of gastroenterology & hepatology.

Levofloxacin based triple therapy as a second-line treatment after failure of helicobacter pylori eradication with standard triple therapy.

M. Kasuga, N. Aoyama, T. Tamura, 2003, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

CYP2C19 Genotype and Pharmacokinetics of Three Proton Pump Inhibitors in Healthy Subjects

M. Kasuga, Y. Tanigawara, N. Aoyama, 2001, Pharmaceutical Research.

Optimal dose of omeprazole for CYP2C19 extensive metabolizers in anti-Helicobacter pylori therapy: pharmacokinetic considerations.

M. Kasuga, N. Aoyama, T. Sakaeda, 2002, Biological & pharmaceutical bulletin.

Sufficient effect of 1-week omeprazole and amoxicillin dual treatment for Helicobacter pylori eradication in cytochrome P450 2C19 poor metabolizers.

M. Kasuga, Y. Tanigawara, N. Aoyama, 1999, Journal of gastroenterology.

[A case of rheumatoid arthritis (RA) with drug-induced acute pancreatitis due to mizoribine].

M. Kasuga, N. Aoyama, H. Yamada, 1997, Ryumachi. [Rheumatism].

Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis

K. Haruma, N. Aoyama, J. Akiyama, 2023, BMC Gastroenterology.

No significant difference in neutrophil activation found among three H2RAs.

M. Kasuga, Y. Morita, N. Aoyama, 2007, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

Favorable Genetic Polymorphisms Predictive of Clinical Outcome of Chemoradiotherapy for Stage II/III Esophageal Squamous Cell Carcinoma in Japanese

M. Kasuga, T. Azuma, N. Aoyama, 2007, American journal of clinical oncology.

Helicobacter pylori VacA Activates the p38/Activating Transcription Factor 2-mediated Signal Pathway in AZ-521 Cells*

T. Hirayama, M. Noda, J. Moss, 2004, Journal of Biological Chemistry.

Application of Bead-ELISA method to detect Helicobacter pylori VacA.

T. Hirayama, N. Aoyama, H. Kurazono, 1999, Microbial pathogenesis.

The relationship between gastric emptying determined by the breath test and H. pylori.

M. Kasuga, N. Aoyama, Y. Morita, 2007, Hepato-gastroenterology.

N-acetyltransferase 2 genotype-related sulfapyridine acetylation and its adverse events.

M. Kasuga, Y. Tanigawara, N. Aoyama, 2002, Biological & pharmaceutical bulletin.

HLA-DQB1 locus and the development of atrophic gastritis with Helicobacter pylori infection.

M. Kasuga, N. Aoyama, K. Satonaka, 1999, Journal of gastroenterology.