T. Darrow

发表

Mutations of the BRAF gene in human cancer

A. Nicholson, M. Stratton, P. Futreal, 2002, Nature.

Melanoma, a tumor based on a mutant stem cell?

J. A. Burch, J. Grichnik, H. Seigler, 2006, The Journal of investigative dermatology.

The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens.

C. Slingluff, H. Seigler, T. Darrow, 1989, Journal of immunology.

Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines.

R. Henderson, J. Shabanowitz, D. Hunt, 1994, Science.

Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens

D. Hunt, V. Engelhard, C. Slingluff, 2000, Cancer Immunology, Immunotherapy.

Dual recognition of a human cytotoxic T-cell clone for melanoma antigens.

T. Saida, T. Darrow, F. Obata, 1996, Cancer research.

Human cytotoxic T cells specific for autologous melanoma cells: successful generation from lymph node cells in seven consecutive cases.

C. Slingluff, H. Seigler, T. Darrow, 1988, Journal of the National Cancer Institute.

MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele.

H. Seigler, T. Darrow, M. Quinn-Allen, 1991, Journal of immunology.

Retrovirus‐Mediated Gene Transfer of the Human γ‐IFN Gene: A Therapy for Cancer

T. Darrow, B. Howard, M. Burrascano, 1994 .

Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells.

R. Zennadi, H. Seigler, T. Darrow, 2001, Cellular immunology.

Murine dendritic cells transfected with human GP100 elicit both antigen‐specific CD8+ and CD4+ T‐cell responses and are more effective than DNA vaccines at generating anti‐tumor immunity

J. Grichnik, H. Seigler, T. Darrow, 1999, International journal of cancer.

Melanoma-specific cytotoxic T cells generated from peripheral blood lymphocytes. Implications of a renewable source of precursors for adoptive cellular immunotherapy.

C. Slingluff, H. Seigler, T. Darrow, 1989, Annals of surgery.

T-Cells Using HLA-A 2-matched Allogeneic Melanomas Generation of Human Autologous Melanoma-specific Cytotoxic Updated

C. Slingluff, T. Darrow, N. J. Crowley, 2006 .

Inhibition of the growth of human melanoma xenografts in nude mice by human tumor‐specific cytotoxic T‐cells

C. Slingluff, H. Seigler, T. Darrow, 1990, Journal of surgical oncology.

Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.

C. Slingluff, H. Seigler, T. Darrow, 1990, Cancer research.

Autologous lymph node cell‐derived tumor‐specific cytotoxic t‐cells for use in adoptive immunotherapy of human melanoma

C. Slingluff, H. Seigler, T. Darrow, 1988, Cancer.

A phase I trial of human gamma interferon transduced autologous tumor cells in patients with disseminated malignant melanoma.

H. Seigler, T. Darrow, J. Barber, 1994, Human gene therapy.

Human T cells specifically activated against autologous malignant melanoma.

C. Slingluff, H. Seigler, T. Darrow, 1987, Archives of surgery.

Immune response of chimpanzee to purified melanoma 250 kilodalton tumor-associated antigen

H. Seigler, T. Darrow, D. M. Haupt, 2004, Cancer Immunology, Immunotherapy.

Transduction of human melanoma cells with interleukin-2 gene reduces tumorigenicity and enhances host antitumor immunity: a nude mouse model.

H. Seigler, T. Darrow, M. Burrascano, 1994, Cellular immunology.

Inhibition of the growth of human melanoma metastases in nude mice by melanoma-specific murine monoclonal antibody.

H. Seigler, T. Darrow, C. Vervaert, 1992, Surgical oncology.

Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow.

H. Seigler, T. Darrow, S. Yang, 1997, Cellular immunology.

Tumor cells cotransduced with B7.1 and γ-IFN induce effective rejection of established parental tumor

H. Seigler, T. Darrow, S. Yang, 1999, Gene Therapy.

Generation of primary tumor-specific cytotoxic T lymphocytes from autologous and human lymphocyte antigen class I-matched allogeneic peripheral blood lymphocytes by B7 gene-modified melanoma cells.

H. Seigler, T. Darrow, S. Yang, 1997, Cancer research.

Modulation of in vitro autologous melanoma-specific cytotoxic T-cell responses by phorbol dibutyrate and ionomycin.

H. Seigler, T. Darrow, M. Quinn-Allen, 1990, Cellular immunology.

Prostaglandin-mediated regulation of the mixed lymphocyte culture and generation of cytotoxic cells.

T. Darrow, R. Tomar, 1980, Cellular immunology.

Human melanoma‐mediated inhibition of autologous CD4+ helper tumor‐infiltrating lymphocyte growth in vitro

H. Seigler, T. Darrow, M. Quinn-Allen, 1992, Cancer.

RECOGNITION AND REGULATION BY MODIFIED SELF

B. Grouix, T. Darrow, L. A. Wilson, 1982, Annals of the New York Academy of Sciences.

Melanoma Antigens Dual Recognition of a Human Cytotoxic T-Cell Clone for Updated

T. Saida, T. Darrow, F. Obata, 2006 .

Clonal analysis of in vivo activated CD8+ cytotoxic T lymphocytes from a melanoma patient responsive to active specific immunotherapy

L. Steinman, J. Oksenberg, T. Darrow, 2005, Cancer Immunology, Immunotherapy.

Dendritic Cells Infected with a Vaccinia Vector Carrying the Human gp100 Gene Simultaneously Present Multiple Specificities and Elicit High-Affinity T Cells Reactive to Multiple Epitopes and Restricted by HLA-A2 and -A31

C. Slingluff, H. Seigler, T. Darrow, 2000, The Journal of Immunology.

and -A3 Multiple Epitopes and Restricted by HLA-A2 and Elicit High-Affinity T Cells Reactive to Simultaneously Present Multiple Specificities Vector Carrying the Human gp100 Gene Dendritic Cells Infected with a Vaccinia

C. Slingluff, H. Seigler, T. Darrow, 2000 .

Modulation of specific active immunization against murine melanoma using recombinant cytokines.

W. Ricci, H. Seigler, T. Darrow, 1996, Surgical oncology.

Immunological memory induced by genetically transduced tumor cells

H. Seigler, T. Darrow, J. Barber, 1996, Annals of Surgical Oncology.

Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity.

H. Seigler, T. Darrow, S. Osanto, 1994, Cancer gene therapy.

Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells.

H. Seigler, T. Darrow, J. Barber, 1996, Cellular immunology.

Recognition and lysis of human melanoma by a CD3+, CD4+, CD8- T-cell clone restricted by HLA-A2.

H. Seigler, T. Darrow, Z. Abdel-wahab, 1996, Cellular immunology.

Augmentation of syngeneic tumor-specific immunity by semiallogeneic cell hybrids.

D. Scott, T. Darrow, D. Toffaletti, 1983, Journal of immunology.

Generation of autologous tumor-specific cytotoxic T-cells using HLA-A region matched allogeneic melanoma.

H. Seigler, T. Darrow, N. J. Crowley, 1989, Current surgery.

Mutations of the BRAF gene in human cancer

A. Nicholson, P. Futreal, R. Wooster, 2002, Nature.

Renal Cell Carcinoma Treated with Continuous‐Infusion Interleukin‐2 with Ex Vivo‐Activated Killer Cells

K. Foon, J. Park, T. Darrow, 1992, Journal of immunotherapy : official journal of the Society for Biological Therapy.

Recently accepted manuscripts

T. Darrow, Radiation Oncologist, Harry Kujari, 2022 .