I. Galve-Roperh

发表

Mechanism of extracellular signal-regulated kinase activation by the CB(1) cannabinoid receptor.

G. Velasco, I. Galve-Roperh, D. Rueda, 2002, Molecular pharmacology.

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

S. Spiegel, A. Olivera, I. Galve-Roperh, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Adaptations of the β-adrenoceptor-adenylyl cyclase system in rat skeletal muscle to endurance physical training

I. Galve-Roperh, I. Díaz-Laviada, J. L. Nieto, 1997, Pflügers Archiv.

Targeting Cannabinoid Receptors in Brain Tumors

A. Carracedo, G. Velasco, I. Galve-Roperh, 2008 .

Cannabinoids and Gliomas

A. Carracedo, G. Velasco, I. Galve-Roperh, 2007, Molecular Neurobiology.

Non‐psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation

I. Galve-Roperh, M. Guzmán, R. Mechoulam, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease

I. Galve-Roperh, G. Appendino, C. Del Río, 2016, Scientific Reports.

A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme

G. Velasco, I. Galve-Roperh, M. Guzmán, 2006, British Journal of Cancer.

Cannabinoids and ceramide: two lipids acting hand-by-hand.

G. Velasco, I. Galve-Roperh, M. Guzmán, 2005, Life sciences.

v 9-Tetrahydrocannabinol induces apoptosis in C 6 glioma cells

P. Brachet, I. Galve-Roperh, Cristina Saènchez, 1998 .

Δ9‐Tetrahydrocannabinol induces apoptosis in C6 glioma cells

P. Brachet, I. Galve-Roperh, M. Guzmán, 1998 .

Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.

M. L. de Ceballos, G. Velasco, S. Y. Cajal, 2001, Cancer research.

CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling*

I. Galve-Roperh, M. Guzmán, J. Palazuelos, 2011, The Journal of Biological Chemistry.

Anandamide deficiency and heightened neuropathic pain in aged mice

B. Oertel, N. Ferreirós, I. Galve-Roperh, 2013, Neuropharmacology.

Delta9-tetrahydrocannabinol induces apoptosis in C6 glioma cells.

P. Brachet, I. Galve-Roperh, M. Guzmán, 1998, FEBS letters.

Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia

E. Aronica, I. Galve-Roperh, M. Guzmán, 2019, Front. Pharmacol..

Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice

B. Lutz, I. Galve-Roperh, M. Guzmán, 2022, Cell Death & Disease.

Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration

R. Bajo-Grañeras, I. Galve-Roperh, M. Guzmán, 2019, Translational Neurodegeneration.

Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain

G. Mengod, M. Vilaró, R. Bajo-Grañeras, 2021, The Journal of Neuroscience.

Ceramide Signaling in Cannabinoid Action

G. Velasco, I. Galve-Roperh, D. Rueda, 2002 .

Involvement of sphingomyelin hydrolysis and the mitogen-activated protein kinase cascade in the Delta9-tetrahydrocannabinol-induced stimulation of glucose metabolism in primary astrocytes.

I. Galve-Roperh, D. Rueda, M. Guzmán, 1998, Molecular pharmacology.

MicroRNA let-7d is a target of cannabinoid CB1 receptor and controls cannabinoid signaling

I. Galve-Roperh, M. Guzmán, C. Blázquez, 2016, Neuropharmacology.

R-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)-pyrrolo-[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphtalenylmethanone (WIN-2) ameliorates experimental autoimmune encephalomyelitis and induces encephalitogenic T cell apoptosis: partial involvement of the CB(2) receptor.

I. Galve-Roperh, A. García-Merino, Antonio J. Sánchez, 2006, Biochemical pharmacology.

Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination

J. Baufreton, R. Bajo-Grañeras, G. Marsicano, 2020, eLife.

Evidence for the Lack of Involvement of Sphingomyelin Hydrolysis in the Tumor Necrosis Factor‐Induced Secretion of Nerve Growth Factor in Primary Astrocyte Cultures

I. Galve-Roperh, C. Sánchez, T. Levade, 1998, Journal of neurochemistry.

Induction of nerve growth factor synthesis by sphingomyelinase and ceramide in primary astrocyte cultures.

I. Galve-Roperh, I. Díaz-Laviada, A. Haro, 1997, Brain research. Molecular brain research.

Ceramide‐induced translocation of protein kinase C ζ in primary cultures of astrocytes

I. Galve-Roperh, I. Díaz-Laviada, A. Haro, 1997, FEBS letters.

Levels and activity of brain protein kinase C α and ζ during the aging of the medfly

I. Galve-Roperh, P. García-Barreno, J. M. Malpartida, 1996, Mechanisms of Ageing and Development.

cAMP signalling mechanisms with aging in the Ceratitis capitata brain

I. Galve-Roperh, J. M. Malpartida, A. Haro, 1997, Mechanisms of Ageing and Development.

The CB(1) cannabinoid receptor of astrocytes is coupled to sphingomyelin hydrolysis through the adaptor protein fan.

I. Galve-Roperh, D. Rueda, M. Guzmán, 2001, Molecular pharmacology.

Ceramide: a new second messenger of cannabinoid action.

I. Galve-Roperh, M. Guzmán, C. Sánchez, 2001, Trends in pharmacological sciences.

The CB1 Cannabinoid Receptor Is Coupled to the Activation of c-Jun N-Terminal Kinase

I. Galve-Roperh, D. Rueda, M. Guzmán, 2000 .

The CB(1) cannabinoid receptor is coupled to the activation of c-Jun N-terminal kinase.

I. Galve-Roperh, D. Rueda, M. Guzmán, 2000, Molecular pharmacology.

Cannabinoid signalling in the immature brain: Encephalopathies and neurodevelopmental disorders

I. Galve-Roperh, A. Gutiérrez-Rodríguez, J. Martínez-Orgado, 2018, Biochemical pharmacology.

Javier mTORC 1 Signaling Neural Progenitor Cell Proliferation via Cannabinoid Receptors Promote 2 CB

I. Galve-Roperh, M. Guzmán, J. Palazuelos, 2011 .

CB 2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC 1 signaling

I. Galve-Roperh, M. Guzmán, J. Palazuelos, 2011 .

Regulation of nerve growth factor secretion and mRNA expression by bacterial lipopolysaccharide in primary cultures of rat astrocytes

P. Brachet, I. Galve-Roperh, I. Díaz-Laviada, 1997, Journal of neuroscience research.

Prenatal exposure to cannabinoids evokes long-lasting functional alterations by targeting CB1 receptors on developing cortical neurons

B. Lutz, I. Galve-Roperh, M. Guzmán, 2015, Proceedings of the National Academy of Sciences.

Long-term hippocampal interneuronopathy drives sex-dimorphic spatial memory impairment induced by prenatal THC exposure

B. Lutz, I. Galve-Roperh, M. Guzmán, 2020, Neuropsychopharmacology.

Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation.

I. Galve-Roperh, M. Guzmán, M. Maccarrone, 2013, Progress in lipid research.

The Endocannabinoid System Promotes Astroglial Differentiation by Acting on Neural Progenitor Cells

B. Cravatt, G. Marsicano, B. Lutz, 2006, The Journal of Neuroscience.

The endocannabinoid system drives neural progenitor proliferation

B. Cravatt, G. Marsicano, B. Lutz, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Endocannabinoid Anandamide Inhibits Neuronal Progenitor Cell Differentiation through Attenuation of the Rap1/B-Raf/ERK Pathway*

I. Galve-Roperh, D. Rueda, M. Guzmán, 2002, The Journal of Biological Chemistry.

De novo‐synthesized ceramide signals apoptosis in astrocytes via extracellular signal‐regulated kinase

I. Galve-Roperh, M. Guzmán, C. Blázquez, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Stimulation of Ketogenesis by Cannabinoids in Cultured Astrocytes Defines Carnitine Palmitoyltransferase I as a New Ceramide‐Activated Enzyme

I. Galve-Roperh, M. Guzmán, C. Sánchez, 1999, Journal of neurochemistry.

Send Orders of Reprints at Reprints@benthamscience.net Cannabinoids, Neurogenesis and Antidepressant Drugs: Is There a Link?

F. Guimarães, I. Galve-Roperh, A. Campos, 2022 .

Cannabinoids Induce Glioma Stem-like Cell Differentiation and Inhibit Gliomagenesis*

A. Carracedo, G. Velasco, I. Galve-Roperh, 2007, Journal of Biological Chemistry.

Hypothesis: cannabinoid therapy for the treatment of gliomas?

G. Velasco, I. Galve-Roperh, M. Guzmán, 2004, Neuropharmacology.

Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

M. Cortés, M. Izquierdo, I. Galve-Roperh, 2000, Nature Medicine.

CB1 Cannabinoid Receptor-Dependent Activation of mTORC1/Pax6 Signaling Drives Tbr2 Expression and Basal Progenitor Expansion in the Developing Mouse Cortex.

I. Galve-Roperh, M. Guzmán, T. Aguado, 2015, Cerebral cortex.

Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons

R. Zechner, R. Zimmermann, I. Galve-Roperh, 2019, Neuropharmacology.

A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease

I. Galve-Roperh, M. Guzmán, S. Ortega‐Gutiérrez, 2016, Journal of Neurology.

A restricted population of CB1 cannabinoid receptors with neuroprotective activity

J. J. Ferrero, B. Lutz, I. Galve-Roperh, 2014, Proceedings of the National Academy of Sciences.

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease.

J. Lucas, G. Marsicano, B. Lutz, 2011, Brain : a journal of neurology.

Δ9‐Tetrahydrocannabinol promotes functional remyelination in the mouse brain

I. Galve-Roperh, M. Guzmán, C. Matute, 2021, British journal of pharmacology.

The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway

B. Lutz, M. Sendtner, I. Galve-Roperh, 2015, Cell Death and Differentiation.

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

Í. Azcoitia, I. Galve-Roperh, M. Guzmán, 2009, Brain : a journal of neurology.

The CB1 Cannabinoid Receptor Mediates Excitotoxicity-induced Neural Progenitor Proliferation and Neurogenesis*

G. Marsicano, B. Lutz, M. Sendtner, 2007, Journal of Biological Chemistry.

The Endocannabinoid System and Neurogenesis in Health and Disease

I. Galve-Roperh, M. Guzmán, T. Aguado, 2007, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

The emerging functions of endocannabinoid signaling during CNS development.

K. Mackie, T. Harkany, I. Galve-Roperh, 2007, Trends in pharmacological sciences.

Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders

F. Guimarães, I. Galve-Roperh, F. Gomes, 2017, Front. Pharmacol..

Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

S. Milstien, S. Spiegel, I. Galve-Roperh, 2002, The Journal of cell biology.

Δ 9 -Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption

F. Guimarães, I. Galve-Roperh, A. Zuardi, 2015, European Neuropsychopharmacology.

Direct Calcium Binding Results in Activation of Brain Serine Racemase*

I. Galve-Roperh, I. Rodrı́guez-Crespo, A. Martı́nez del Pozo, 2002, The Journal of Biological Chemistry.

Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum

F. Ciruela, C. Lluis, B. Lutz, 2017, Neuropsychopharmacology.

Pathway-Specific Control of Striatal Neuron Vulnerability by Corticostriatal Cannabinoid CB1 Receptors

J. J. Ferrero, G. Marsicano, I. Galve-Roperh, 2018, Cerebral cortex.

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.

F. Guimarães, I. Galve-Roperh, M. Guzmán, 2013, The international journal of neuropsychopharmacology.

Control of the cell survival/death decision by cannabinoids

I. Galve-Roperh, M. Guzmán, C. Sánchez, 2001, Journal of Molecular Medicine.

Involvement of the cAMP/protein kinase A pathway and of mitogen‐activated protein kinase in the anti‐proliferative effects of anandamide in human breast cancer cells

I. Galve-Roperh, D. Rueda, M. Guzmán, 1999, FEBS letters.

Possible therapeutic applications of cannabis in the neuropsychopharmacology field

I. Galve-Roperh, M. Guzmán, J. Fernández-Ruiz, 2020, European Neuropsychopharmacology.

Endocannabinoids via CB1 receptors act as neurogenic niche cues during cortical development

I. Galve-Roperh, M. Guzmán, J. Díaz-Alonso, 2012, Philosophical Transactions of the Royal Society B: Biological Sciences.

The endocannabinoid system and the regulation of neural development: potential implications in psychiatric disorders

I. Galve-Roperh, M. Guzmán, T. Aguado, 2009, European Archives of Psychiatry and Clinical Neuroscience.

Δ9‐Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo

I. Galve-Roperh, M. Guzmán, C. Matute, 2020, Glia.

The CB 1 cannabinoid receptor signals striatal neuroprotection via a PI 3 K / Akt / mTORC 1 / BDNF pathway

B. Lutz, M. Sendtner, I. Galve-Roperh, 2015 .

Mechanisms of control of neuron survival by the endocannabinoid system.

I. Galve-Roperh, M. Guzmán, T. Aguado, 2008, Current pharmaceutical design.

Endocannabinoids: a new family of lipid mediators involved in the regulation of neural cell development.

G. Velasco, I. Galve-Roperh, D. Rueda, 2006, Current pharmaceutical design.

The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

N. Davoust, S. Nataf, I. Galve-Roperh, 2008, The Journal of biological chemistry.

Cannabinoids as Regulators of Neural Development and Adult Neurogenesis

F. Guimarães, I. Galve-Roperh, A. Campos, 2017 .

Cannabinoids and cell fate.

I. Galve-Roperh, M. Guzmán, C. Sánchez, 2002, Pharmacology & therapeutics.

Addition of phosphatidylcholine-phospholipase C induces cellular redistribution and phosphorylation of protein kinase C ξ in C 6 glial cells

I. Galve-Roperh, I. Díaz-Laviada, J. M. Malpartida, 1996, Neuroscience Letters.

Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke

O. Hurtado, V. G. Romera, I. Galve-Roperh, 2017, Stroke.

Loss of Cannabinoid CB1 Receptors Induces Cortical Migration Malformations and Increases Seizure Susceptibility

F. Guillemot, P. Garcez, M. Parsons, 2016, Cerebral cortex.

Phosphatidylcholine‐phospholipase C mediates the induction of nerve growth factor in cultured glial cells

P. Brachet, P. Naveilhan, I. Galve-Roperh, 1995, FEBS letters.

Sustained Gq-Protein Signaling Disrupts Striatal Circuits via JNK

J. Cazalets, I. Galve-Roperh, M. Guzmán, 2016, The Journal of Neuroscience.

The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis

F. Guillemot, P. Garcez, Clementine Hofmann, 2012, The Journal of Neuroscience.

Endocannabinoid signalling in stem cells and cerebral organoids drives differentiation to deep layer projection neurons via CB1 receptors

I. Galve-Roperh, M. Guzmán, I. Liste, 2020, Development.

The CB2 Cannabinoid Receptor Controls Myeloid Progenitor Trafficking

N. Davoust, S. Nataf, I. Galve-Roperh, 2008, Journal of Biological Chemistry.

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning

L. Nguyen, J. Mulder, E. Keimpema, 2008, Proceedings of the National Academy of Sciences.

Control of a hippocampal recurrent excitatory circuit by cannabinoid receptor-interacting protein Gap43

P. Castillo, G. Marsicano, I. Galve-Roperh, 2023, Nature communications.

The endocannabinoid system drives neural progenitor proliferation

B. Cravatt, G. Marsicano, B. Lutz, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

CB1 Cannabinoid Receptor-Dependent Activation of mTORC1/Pax6 Signaling Drives Tbr2 Expression and Basal Progenitor Expansion in the Developing Mouse Cortex.

I. Galve-Roperh, M. Guzmán, T. Aguado, 2015, Cerebral cortex.