J. Kloehn

发表

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

Eleanor C. Saunders, M. Ng, E. Saunders, 2014, PLoS pathogens.

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

A. Keniry, I. G. Romero, C. Wells, 2020, Nature Communications.

Characterization of Metabolically Quiescent Leishmania Parasites in Murine Lesions Using Heavy Water Labeling

Michael J. Dagley, Eleanor C. Saunders, E. Saunders, 2015, PLoS pathogens.

Leishmania carbon metabolism in the macrophage phagolysosome- feast or famine?

Michael J. Dagley, Eleanor C. Saunders, E. Saunders, 2015, F1000Research.

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

J. Kloehn, D. Soldati-Favre, E. Varesio, 2022, Nature communications.

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

J. Kloehn, D. Soldati-Favre, E. Varesio, 2021, bioRxiv.

Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism.

Anush Chiappino-Pepe, A. Hehl, V. Hatzimanikatis, 2020, Cell host & microbe.

Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

Rebecca D. Oppenheim, J. Kloehn, Y. Couté, 2020, BMC Biology.

Vitamin and cofactor acquisition in apicomplexans: Synthesis versus salvage

J. Kloehn, D. Soldati-Favre, M. Lunghi, 2019, The Journal of Biological Chemistry.

Using metabolomics to dissect host-parasite interactions.

Michael J. Dagley, Eleanor C. Saunders, E. Saunders, 2016, Current opinion in microbiology.

Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse.

Micah L. Burch, J. Kloehn, M. McConville, 2015, Biochemical and biophysical research communications.

A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites.

Spencer J. Williams, T. Nero, M. Parker, 2019, Cell host & microbe.

In vivo cardiac glucose metabolism in the high-fat fed mouse: Comparison of euglycemic-hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach.

Micah L. Burch, J. Kloehn, M. McConville, 2015, Biochemical and biophysical research communications.

Untargeted Metabolomics Uncovers the Essential Lysine Transporter in Toxoplasma gondii

J. Kloehn, D. Soldati-Favre, E. Varesio, 2021, Metabolites.

Using metabolomic approaches to characterize the human pathogen Leishmania in macrophages

Eleanor C. Saunders, E. Saunders, J. Kloehn, 2016 .

Analysis of Mammalian Cell Proliferation and Macromolecule Synthesis Using Deuterated Water and Gas Chromatography-Mass Spectrometry

O. Sieber, J. Kloehn, M. McConville, 2016, Metabolites.

Overexpression of sphingosine kinase 1 in liver reduces triglyceride content in mice fed a low but not high-fat diet.

Micah L. Burch, S. Lamon, J. Kloehn, 2015, Biochimica et biophysica acta.

Supply and demand—heme synthesis, salvage and utilization by Apicomplexa

J. Kloehn, D. Soldati-Favre, Clare R. Harding, 2020, The FEBS journal.

Ceramide biosynthesis is critical for establishment of the intracellular niche of Toxoplasma gondii

B. Maco, J. Kloehn, J. Hannich, 2022, Cell reports.

The metabolic pathways and transporters of the plastid organelle in Apicomplexa.

J. Kloehn, D. Soldati-Favre, Clémentine Lacour, 2021, Current opinion in microbiology.

Metabolite salvage and restriction during infection - a tug of war between Toxoplasma gondii and its host.

J. Kloehn, D. Soldati-Favre, Pierre-Mehdi Hammoudi, 2020, Current opinion in biotechnology.

Analysis of the Physiological and Metabolic State of Leishmania Using Heavy Water Labeling.

J. Kloehn, M. McConville, Joachim Kloehn, 2020, Methods in molecular biology.

carbon metabolism in the macrophage Leishmania phagolysosome-feast or famine ?

Michael J. Dagley, Eleanor C. Saunders, E. Saunders, 2015 .

Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization

P. François, S. Rudaz, S. Hapfelmeier, 2020, eLife.

Metabolic networks and metabolomics

Christopher J. Tonkin, J. Kloehn, M. McConville, 2020 .

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

Matthew E. Ritchie, A. Keniry, I. G. Romero, 2020, Nature Communications.

Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii

J. Kloehn, D. Soldati-Favre, E. Varesio, 2022, Nature Communications.

eIF4E3 forms an active eIF4F complex during stresses (eIF4FS) targeting mTOR and re-programs the translatome

K. Abid, J. Kloehn, J. Curran, 2021, bioRxiv.

Overexpression of Striated Muscle Activator of Rho Signaling (STARS) Increases C2C12 Skeletal Muscle Cell Differentiation

A. Russell, S. Lamon, J. Kloehn, 2016, Front. Physiol..

Identification of Metabolically Quiescent Leishmania mexicana Parasites in Peripheral and Cured Dermal Granulomas Using Stable Isotope Tracing Imaging Mass Spectrometry

Eleanor C. Saunders, E. Saunders, J. Kloehn, 2021, mBio.

Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis

J. Kloehn, M. McConville, D. Tull, 2016, Scientific Reports.

Evolution of a New Pathway of Reserve Carbohydrate Biosynthesis in Leishmania Parasites

Spencer J. Williams, T. Nero, M. Parker, 2019, SSRN Electronic Journal.

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages

Eleanor C. Saunders, E. Saunders, J. Kloehn, 2015, PLoS pathogens.

Pantothenate biosynthesis in Toxoplasma gondii tachyzoites is not a drug target.

C. Spry, K. Saliba, G. V. van Dooren, 2023, International journal for parasitology. Drugs and drug resistance.