A. Cuenda

A. Risco, A. Cuenda, A. Álvarez-Barrientos, 2015, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38γ and p38δ, linking inflammation and cancer in colitis-associated colon cancer.

A. Risco, A. Cuenda, Rafal Zur, 2014, Cancer research.

Colitis-Associated Colon Cancer , Linking Inflammation and Cancer in δ and p 38 γ Kinases p 38 Pro-Oncogenic Role of Alternative p 38 Mitogen-Activated Protein

A. Risco, A. Cuenda, Rafal Zur, 2014 .

Alternative p38 MAPKs Are Essential for Collagen‐Induced Arthritis

A. Risco, A. Cuenda, M. Pérez-Lorenzo, 2014, Arthritis & rheumatology.

New Insights into the p38γ and p38δ MAPK Pathways

A. Risco, A. Cuenda, 2011, Journal of signal transduction.

MAPK12 (mitogen-activated protein kinase 12)

A. Cuenda, Mi Cerezo-Guisado, 2011 .

Evidence of p38γ and p38δ involvement in cell transformation processes.

J. Arthur, A. Cuenda, D. Gallego-Ortega, 2011, Carcinogenesis.

MAPK13 (mitogen-activated protein kinase 13)

A. Cuenda, Mi Cerezo-Guisado, 2011 .

Differential activation of p38MAPK isoforms by MKK6 and MKK3.

Roger J. Davis, A. Risco, A. Cuenda, 2010, Cellular signalling.

p38γ regulates interaction of nuclear PSF and RNA with the tumour-suppressor hDlg in response to osmotic shock

J. Arthur, D. Campbell, A. Cuenda, 2010, Journal of Cell Science.

Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases

Philip R. Cohen, M. Goedert, M. Hasegawa, 1997, FEBS letters.

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.

P. Cohen, C. Bryant, J. Murray, 1999, Cellular signalling.

Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis*

P. Cohen, A. Cuenda, 1999, The Journal of Biological Chemistry.

Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.

D. Campbell, A. Cuenda, Yvonne Kuma, 2004, The Biochemical journal.

Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.

M. Goedert, M. Hasegawa, A. Cuenda, 2004, The Biochemical journal.

p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

M. Goedert, J. Arthur, M. Peggie, 2005, The EMBO journal.

Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assembly

M. Goedert, D. Campbell, A. Cuenda, 2005, Journal of Cell Science.

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

I. Benjamin, C. Sutherland, S. Keyse, 2016, Molecular and Cellular Biology.

Alternative ERK5 regulation by phosphorylation during the cell cycle.

D. Campbell, N. Gómez, J. Lizcano, 2010, Cellular signalling.

Evolutionary analysis of p38 stress-activated kinases in unicellular relatives of animals suggests an ancestral function in osmotic stress

I. Ruiz-Trillo, A. Cuenda, J. Sanz-Ezquerro, 2022, bioRxiv.

maintenance of the immature state of human dendritic cells Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent

J. Rodríguez-Fernández, S. Sánchez-Ramón, Á. Corbí, 2014 .

Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells.

A. Dopazo, J. Rodríguez-Fernández, S. Sánchez-Ramón, 2013, Blood.

Methods to assay stress-activated protein kinases.

A. Cuenda, 2000, Methods in molecular biology.

p 38 c and p 38 d reprogram liver metabolism by modulating neutrophil infiltration

F. Sánchez‐Madrid, A. Mora, A. Cuenda, 2016 .

p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration

F. Sánchez‐Madrid, A. Mora, A. Cuenda, 2016, The EMBO journal.

Use of kinase inhibitors to dissect signaling pathways.

D. Alessi, A. Cuenda, 2000, Methods in molecular biology.

Growth Hormone Reprograms Macrophages toward an Anti-Inflammatory and Reparative Profile in an MAFB-Dependent Manner

C. Martínez-A, Blanca Soler Palacios, Á. Corbí, 2020, The Journal of Immunology.

p38γ and p38δ Are Involved in T Lymphocyte Development

D. F. Barber, D. Barber, A. Risco, 2018, Front. Immunol..

TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA

N. Sonenberg, A. Cuenda, E. Martínez-Salas, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold

R. Huganir, K. Nave, D. Sherman, 2016, PLoS biology.

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo(*)

Philip R. Cohen, D. Alessi, A. Saltiel, 1995, The Journal of Biological Chemistry.

BIRB 796 Inhibits All p 38 MAPK Isoforms in Vitro and in Vivo *

J. Bain, A. Cuenda, N. Shpiro, 2005 .

Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli

P. Cohen, L. Mahadevan, A. Cuenda, 1997, Oncogene.

Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6).

P. Cohen, M. Goedert, M. Craxton, 1997, Biochemical Society transactions.

A Mouse Model of Candidiasis.

A. Cuenda, J. Sanz-Ezquerro, P. Fajardo, 2021, Methods in molecular biology.

Quantification and removal of glycogen phosphorylase and other enzymes associated with sarcoplasmic reticulum membrane preparations.

A. Cuenda, C. Gutiérrez-Merino, F. Henao, 1994, Biochimica et biophysica acta.

Modulation by phosphorylation of glycogen phosphorylase‐sarcoplasmic reticulum interaction

A. Cuenda, C. Gutiérrez-Merino, F. Centeno, 1991, FEBS letters.

The 3F Library: Fluorinated Fsp3-rich Fragments for Expeditious 19F-NMR-based Screening.

A. Cuenda, C. Rademacher, M. Clausen, 2019, Angewandte Chemie.

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis

J. Paramio, A. Risco, A. Cuenda, 2015, Oncotarget.

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

Philip R. Cohen, P. Cohen, John C. Lee, 1995, FEBS letters.

Hyperosmotic Stress Induces Tau Proteolysis by Caspase‐3 Activation in SH‐SY5Y Cells

J. Alonso, A. Cuenda, F. Centeno, 2016, Journal of cellular biochemistry.

Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

Philip R. Cohen, Michel Goedert, M. Goedert, 1997, The EMBO journal.

Jcb: Article

M. Rudnicki, J. Ranish, S. Kuang, 2022 .

BIRB796 Inhibits All p38 MAPK Isoforms in Vitro and in Vivo*

Jenny Bain, J. Bain, A. Cuenda, 2005, Journal of Biological Chemistry.

Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1.

A. Cuenda, D. Dorow, D S Dorow, 1998, The Biochemical journal.

Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition.

P. Cohen, M. Goedert, M. Spillantini, 1999, The Journal of biological chemistry.

Activation of the novel stress‐activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

Philip R. Cohen, M. Craxton, A. Cuenda, 1997, The EMBO journal.

Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress‐ and cytokine‐stimulated monocytes and epithelial cells.

P. Cohen, M. Jones, A. Nebreda, 1996, The EMBO journal.

Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells.

Philip R. Cohen, P. Cohen, J. Rouse, 1996, European journal of biochemistry.

Mitogen-activated protein kinase kinase 4 (MKK4).

A. Cuenda, 2000, The international journal of biochemistry & cell biology.

Mitogen-Activated Protein Kinases (MAPK) in Cancer

A. Cuenda, 2018 .

Phosphorylation of the discs large tumour suppressor protein controls its membrane localisation and enhances its susceptibility to HPV E6-induced degradation

L. Banks, A. Cuenda, P. Massimi, 2006, Oncogene.

ERK5 pathway regulates the phosphorylation of tumour suppressor hDlg during mitosis.

J. Arthur, D. Campbell, A. Cuenda, 2010, Biochemical and biophysical research communications.

Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation

M. Peggie, A. Cuenda, G. Sabio, 2009, The FEBS journal.

Kinetic characterization of the normal and procaine-perturbed reaction cycles of the sarcoplasmic reticulum calcium pump.

A. Cuenda, S. Orlowski, P. Champeil, 1991, European journal of biochemistry.

p38α Antagonizes p38γ Activity through c-Jun-dependent Ubiquitin-proteasome Pathways in Regulating Ras Transformation and Stress Response*

A. Cuenda, Rongshan Li, Songwang Hou, 2007, Journal of Biological Chemistry.

p38γ and p38δ as biomarkers in the interplay of colon cancer and inflammatory bowel diseases

A. Cuenda, K. Astakhova, A. Barbáchano, 2022, Cancer communications.

Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity

M. Netea, S. Alemany, A. Risco, 2018, EMBO molecular medicine.

p38γ and p38δ: From Spectators to Key Physiological Players.

A. Cuenda, J. Sanz-Ezquerro, 2017, Trends in biochemical sciences.

MAPK7 (mitogen-activated protein kinase 7)

A. Cuenda, F. Iñesta-Vaquera, 2011 .

Editorial: Mitogen Activated Protein Kinases

J. Lizcano, A. Cuenda, J. Lozano, 2017, Front. Cell Dev. Biol..

The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor.

W. Fiers, P. Cohen, John C. Lee, 1996, The EMBO journal.

Alternative p38 MAPK Pathways

A. Cuenda, G. Sabio, Yvonne Kuma, 2007 .

p38 MAPK Down-regulates Fibulin 3 Expression through Methylation of Gene Regulatory Sequences

A. Porras, A. Cuenda, C. Roncero, 2014, The Journal of Biological Chemistry.

Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells

D. Alessi, J. Alonso, J. M. Fuentes, 2001, Journal of neurochemistry.

Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.

J. Alonso, A. Mora, A. Risco, 2002, Cellular signalling.

Activation of the MAP kinase homologue RK requires the phosphorylation of Thr‐180 and Tyr‐182 and both residues are phosphorylated in chemically stressed KB cells

P. Cohen, A. Nebreda, A. Cuenda, 1995, FEBS letters.

Mitogen Activated Protein Kinases ( MAPKs ) , New Stars in the MAPK Galaxy

A. Risco, A. Cuenda, D. Alsina-Beauchamp, 2016 .

p38γ MAPK Cooperates with c-Jun in trans-Activating Matrix Metalloproteinase 9*

T. Iftner, A. Cuenda, Rong-shan Li, 2010, The Journal of Biological Chemistry.

CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway.

P. Cohen, M. Tessier-Lavigne, M. Gaestel, 2006, Cellular signalling.

Ca 2 + Uptake Coupled to Glycogen Phosphorolysis in the Glycogenolytic-Sarcoplasmic Reticulum Complex from Rat Skeletal Muscle

A. Cuenda, C. Gutiérrez-Merino, M. Nogues, 2013 .

Ca2+ Uptake Coupled to Glycogen Phosphorolysis in the Glycogenolytic-Sarcoplasmic Reticulum Complex from Rat Skeletal Muscle

A. Cuenda, C. Gutiérrez-Merino, F. Henao, 1996, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Distances between functional sites of the Ca2+ + Mg2(+)-ATPase from sarcoplasmic reticulum using Co2+ as a spectroscopic ruler.

A. Cuenda, C. Gutiérrez-Merino, F. Henao, 1990, European journal of biochemistry.

The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells.

P. Cohen, A. Cuenda, F. Thomson, 1995, The Biochemical journal.

Functional Significance of SRJ Domain Mutations in CITED2

S. Bamforth, S. Bhattacharya, H. Watkins, 2012, PloS one.

Molecular Medicine p 38 c / p 38 d regulate C . albicans infection

M. Netea, S. Alemany, A. Risco, 2018 .

p38γMAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions

B. Trapp, L. Wrabetz, A. Cuenda, 2023, bioRxiv.

p38δ controls Mitogen- and Stress-activated Kinase-1 (MSK1) function in response to toll-like receptor activation in macrophages

A. Cuenda, J. Sanz-Ezquerro, D. González-Romero, 2023, Frontiers in Cell and Developmental Biology.

TIBS 1343 No . of Pages 12 Review p 38 g and p 38 d : From Spectators to Key Physiological Players

A. Cuenda, J. Sanz-Ezquerro, 2017 .

The 3F Library: Fluorinated Fsp 3 ‐Rich Fragments for Expeditious 19 F NMR Based Screening

A. Cuenda, C. Rademacher, M. Clausen, 2019 .

The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ.

P. Cohen, S. Arthur, C. Eyers, 2005, The Biochemical journal.

Stress-activated Protein Kinase-3 Interacts with the PDZ Domain of α1-Syntrophin

P. Cohen, M. Goedert, M. Spillantini, 1999, The Journal of Biological Chemistry.

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

D. F. Barber, D. Barber, J. Arthur, 2012, Proceedings of the National Academy of Sciences.

p38δ and PKD1: Kinase Switches for Insulin Secretion

A. Nebreda, A. Cuenda, 2009, Cell.

SKK4, a novel activator of stress‐activated protein kinase‐1 (SAPK1/JNK)

Philip R. Cohen, M. Goedert, A. Cuenda, 1997, FEBS letters.

Emerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2

J. Arthur, P. Crespo, C. Tournier, 2016, Front. Cell Dev. Biol..

p38γ and p38δ modulate innate immune response by regulating MEF2D activation

N. Sonenberg, S. Ley, A. Risco, 2022, bioRxiv.

p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response.

A. Cuenda, Rongshan Li, Songwang Hou, 2007, The Journal of biological chemistry.

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis

J. Paramio, A. Risco, A. Cuenda, 2015, Oncotarget.

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

D. F. Barber, J. Arthur, S. Ley, 2012, Proceedings of the National Academy of Sciences.

Interaction between Glycogen Phosphorylase and Sarcoplasmic Reticulum Membranes and Its Functional Implications (*)

A. Cuenda, C. Gutiérrez-Merino, F. Henao, 1995, The Journal of Biological Chemistry.

p38&dgr; MAPK: A Novel Regulator of NLRP3 Inflammasome Activation With Increased Expression in Coronary Atherogenesis

J. Tuimala, A. Risco, A. Cuenda, 2016, Arteriosclerosis, thrombosis, and vascular biology.

p38-γ–dependent gene silencing restricts entry into the myogenic differentiation program

M. Rudnicki, J. Ranish, S. Kuang, 2009, The Journal of cell biology.

Fluorescnece anisotropy of fluorescein phosphatidylethanolthiocarbamide in lipid bilayers and in Ca2+-ATPase/lipid reconstituted systems

A. Cuenda, C. Gutiérrez-Merino, F. Henao, 1995 .

Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation

M. Peggie, A. Cuenda, G. Sabio, 2009, The FEBS journal.