Le Xu

Cheng Huang, Xiao-ming Meng, Jun Li, 2019, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Icariin induces apoptosis in breast cancer MCF-7 cells by regulating the MELK mediated PI3K/AKT signaling pathway

Le Xu, Zheng-hong Yu, Ting Chen, 2021, European Journal of Gynaecological Oncology.

B7-H4 correlates with clinical outcome and immunotherapeutic benefit in muscle-invasive bladder cancer.

Le Xu, Jiejie Xu, Yu Zhu, 2022, European journal of cancer.

Functional outcomes and complications following B-TURP versus HoLEP for the treatment of benign prostatic hyperplasia: a review of the literature and Meta-analysis

Le Xu, Hailong Liu, Wei He, 2017, The aging male : the official journal of the International Society for the Study of the Aging Male.

Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells

Le Xu, Heng Zhang, Jiejie Xu, 2013, Cancer science.

Exopolysaccharide, Isolated From a Novel Strain Bifidobacterium breve lw01 Possess an Anticancer Effect on Head and Neck Cancer – Genetic and Biochemical Evidences

Le Xu, Guorong Liu, K. Tian, 2019, Front. Microbiol..

Immune inactivation by CD47 expression predicts clinical outcomes and therapeutic responses in clear cell renal cell carcinoma patients.

Le Xu, Yuan Chang, Baoying Hu, 2022, Urologic oncology.

Beta-1,4-galactosyltransferase II predicts poor prognosis of patients with non-metastatic clear-cell renal cell carcinoma

Yuan-feng Yang, Le Xu, Jiejie Xu, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

High mucin-7 expression is an independent predictor of adverse clinical outcomes in patients with clear-cell renal cell carcinoma

Le Xu, Yuan Chang, Jiejie Xu, 2016, Tumor Biology.

Low Expression of Mucin-4 Predicts Poor Prognosis in Patients With Clear-Cell Renal Cell Carcinoma

Yuan-feng Yang, Le Xu, Yuan Chang, 2016, Medicine.

P2RY14 Is a Potential Biomarker of Tumor Microenvironment Immunomodulation and Favorable Prognosis in Patients With Head and Neck Cancer

Le Xu, Chuanbin Guo, Lin Wang, 2021, Frontiers in Genetics.

Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene.

W. Chung, Yufeng Shen, P. Donahoe, 2021, American journal of human genetics.

Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3β/Snail signaling in renal cell carcinoma

Le Xu, Heng Zhang, Jiejie Xu, 2013, Cancer science.

Molecular Carcinogenesis

Yangyang Fu, Lihuang Su, Mengsi Cai, 2019 .

Increased expression of colony stimulating factor-1 is a predictor of poor prognosis in patients with clear-cell renal cell carcinoma

Le Xu, Jianxin Gu, Jiejie Xu, 2015, BMC Cancer.

Determinants of SARS-CoV-2 entry and replication in airway mucosal tissue and susceptibility in smokers

G. Nolan, R. Andino, K. Mertz, 2021, Cell Reports Medicine.

Tumor-infiltrating TNFRSF9+ CD8+ T cells define different subsets of clear cell renal cell carcinoma with prognosis and immunotherapeutic response

Le Xu, Yuan Chang, Jiejie Xu, 2020, Oncoimmunology.

High expression of interleukin-11 is an independent indicator of poor prognosis in clear-cell renal cell carcinoma

Le Xu, D. Pan, Jiejie Xu, 2015, Cancer science.

Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2

Le Xu, Jianxin Gu, D. Pan, 2013, Cancer science.

Tumor-infiltrating CD39+CD8+ T cells determine poor prognosis and immune evasion in clear cell renal cell carcinoma patients

B. Dai, Le Xu, Yuan Chang, 2020, Cancer Immunology, Immunotherapy.

Identification and validation of an excellent prognosis subtype of muscle-invasive bladder cancer patients with intratumoral CXCR5+ CD8+ T cell abundance

B. Dai, Le Xu, Hongyu Zhang, 2020, Oncoimmunology.

High APOBEC3B expression is a predictor of recurrence in patients with low-risk clear cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, Yuan Chang, 2015, Urologic oncology.

CCR5 blockade inflames antitumor immunity in BAP1-mutant clear cell renal cell carcinoma

B. Dai, Le Xu, Hongyu Zhang, 2020, Journal for ImmunoTherapy of Cancer.

Tumor-associated Macrophage-derived Interleukin-23 Interlinks Kidney Cancer Glutamine Addiction with Immune Evasion.

B. Dai, Le Xu, Yuan Chang, 2019, European urology.

Decreased Expression of SETD2 Predicts Unfavorable Prognosis in Patients With Nonmetastatic Clear-Cell Renal Cell Carcinoma

Le Xu, Yuan Chang, Jiejie Xu, 2015, Medicine.

p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, Jiejie Xu, 2015, Urologic oncology.

ST6Gal-I predicts postoperative clinical outcome for patients with localized clear-cell renal cell carcinoma.

Le Xu, Jiejie Xu, Qian Wu, 2015, Asian Pacific journal of cancer prevention : APJCP.

Tumor miR-125b predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection

Le Xu, D. Pan, Jiejie Xu, 2014, Cancer science.

Increased peripheral blood neutrophil activation phenotypes and NETosis in critically ill COVID-19 patients: a case series and review of the literature

A. Malhotra, N. Coufal, K. Perofsky, 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Prognostic Value of Diametrically Polarized Tumor-Associated Macrophages in Renal Cell Carcinoma

Le Xu, Lian Chen, Guo-min Wang, 2014, Annals of Surgical Oncology.

A three-molecule score based on Notch pathway predicts poor prognosis in non-metastasis clear cell renal cell carcinoma

Le Xu, Jiejie Xu, Yanfeng Li, 2016, Oncotarget.

Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling

Shanshan Wang, Le Xu, Guo-min Wang, 2012, Cancer science.

Interleukin-11 receptor predicts post-operative clinical outcome in patients with early-stage clear-cell renal cell carcinoma.

Le Xu, Jianxin Gu, D. Pan, 2015, Japanese journal of clinical oncology.

Intratumoral CCR5+ neutrophils identify immunogenic subtype muscle-invasive bladder cancer with favorable prognosis and therapeutic responses

B. Dai, Le Xu, Hongyu Zhang, 2020, Oncoimmunology.

Blockade of DC-SIGN+ Tumor-Associated Macrophages Reactivates Antitumor Immunity and Improves Immunotherapy in Muscle-Invasive Bladder Cancer

B. Dai, Le Xu, Yuan Chang, 2020, Cancer Research.

Tumor-associated macrophages expressing galectin-9 identify immunoevasive subtype muscle-invasive bladder cancer with poor prognosis but favorable adjuvant chemotherapeutic response

B. Dai, Le Xu, Yuan Chang, 2019, Cancer Immunology, Immunotherapy.

Prognostic value of preoperative lymphocyte to monocyte ratio in patients with nonmetastatic clear cell renal cell carcinoma

Yuan-feng Yang, Le Xu, Yuan Chang, 2016, Tumor Biology.

Suppression of G6PD induces the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin to block epithelial-mesenchymal transition and lymphatic metastasis

Le Xu, Chuanbin Guo, Lin Wang, 2020, British Journal of Cancer.

Hepatitis B virus X protein promotes hepatoma cell invasion and metastasis by stabilizing Snail protein

Shanshan Wang, Le Xu, Jianxin Gu, 2012, Cancer science.

Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma

Le Xu, Yuan Chang, Jiejie Xu, 2021, Journal for ImmunoTherapy of Cancer.

PAK1 expression determines poor prognosis and immune evasion in metastatic renal cell carcinoma patients.

B. Dai, Le Xu, Yuan Chang, 2019, Urologic oncology.

Stromal LAG-3+ cells infiltration defines poor prognosis subtype muscle-invasive bladder cancer with immunoevasive contexture

B. Dai, Le Xu, Hongyu Zhang, 2020, Journal for immunotherapy of cancer.

Identification and validation of poor prognosis immunoevasive subtype of muscle-invasive bladder cancer with tumor-infiltrating podoplanin+ cell abundance

B. Dai, Le Xu, Hongyu Zhang, 2020, Oncoimmunology.

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

D. Brownfield, J. Spetz, Brian Deskin, 2021, Science Advances.

Latency-associated peptide identifies therapeutically resistant muscle-invasive bladder cancer with poor prognosis

Le Xu, Yuan Chang, Jiejie Xu, 2021, Cancer Immunology, Immunotherapy.

Intratumoral IL22‐producing cells define immunoevasive subtype muscle‐invasive bladder cancer with poor prognosis and superior nivolumab responses

B. Dai, Le Xu, Yuan Chang, 2020, International journal of cancer.

Prognostic value of interleukin-6 and interleukin-6 receptor in organ-confined clear-cell renal cell carcinoma: a 5-year conditional cancer-specific survival analysis

Le Xu, Yuan Chang, Jiejie Xu, 2015, British Journal of Cancer.

High expression of CXC chemokine receptor 6 associates with poor prognosis in patients with clear cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, Yuan Chang, 2017, Urologic oncology.

Granulocyte macrophage colony-stimulating factor predicts postoperative recurrence of clear-cell renal cell carcinoma

Yuan-feng Yang, Le Xu, Yuan Chang, 2016, Oncotarget.

GALNT4 predicts clinical outcome in patients with clear cell renal cell carcinoma.

Le Xu, Jiejie Xu, Jianxin Gu, 2014, The Journal of urology.

High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, L. Meng, 2017, Oncotarget.

CD19+ tumor-infiltrating B-cells prime CD4+ T-cell immunity and predict platinum-based chemotherapy efficacy in muscle-invasive bladder cancer

Y. Zhu, Le Xu, Yuan Chang, 2018, Cancer Immunology, Immunotherapy.

Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer

Y. Zhu, Le Xu, Jiejie Xu, 2022, Journal for ImmunoTherapy of Cancer.

p21‐activated kinase 1 predicts recurrence and survival in patients with non‐metastatic clear cell renal cell carcinoma

Le Xu, Jiejie Xu, Yu Zhu, 2015, International journal of urology : official journal of the Japanese Urological Association.

Notch1 predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection.

Le Xu, Lian Chen, Jiejie Xu, 2015, Urology.

Analysis of energy utilization and body composition in kidney, bladder, and adrenal cancer patients.

Le Xu, Lian Chen, Guo-Hao Wu, 2012, Urologic oncology.

CCL2/CCR2 axis is associated with postoperative survival and recurrence of patients with non-metastatic clear-cell renal cell carcinoma

Le Xu, Jiejie Xu, Lin Zhou, 2016, Oncotarget.

High expression of chemokine CCL2 is associated with recurrence after surgery in clear-cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, Yuan Chang, 2016, Urologic oncology.

Tumor-infiltrating neutrophils predict benefit from adjuvant chemotherapy in patients with muscle invasive bladder cancer

Le Xu, Yuan Chang, Lingli Chen, 2017, Oncoimmunology.

High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma

Yuan-feng Yang, Le Xu, L. Meng, 2017, Oncotarget.

High truncated-O-glycan score predicts adverse clinical outcome in patients with localized clear-cell renal cell carcinoma after surgery.

Le Xu, Yuan Chang, Jiejie Xu, 2017, Oncotarget.

TIGIT and PD-1 expression atlas predicts response to adjuvant chemotherapy and PD-L1 blockade in muscle-invasive bladder cancer

Le Xu, Jiejie Xu, Li Liu, 2022, British Journal of Cancer.

Tumor stroma-infiltrating mast cells predict prognosis and adjuvant chemotherapeutic benefits in patients with muscle invasive bladder cancer

B. Dai, Le Xu, Yuan Chang, 2018, Oncoimmunology.

Positive intratumoral chemokine (C-C motif) receptor 8 expression predicts high recurrence risk of post-operation clear-cell renal cell carcinoma patients

Le Xu, Yuan Chang, Jiejie Xu, 2015, Oncotarget.

Tumor-infiltrating IL-17A+ cells determine favorable prognosis and adjuvant chemotherapeutic response in muscle-invasive bladder cancer

B. Dai, Le Xu, Hongyu Zhang, 2020, Oncoimmunology.

Stromal Tumor-Associated Macrophage Infiltration Predicts Poor Clinical Outcomes in Muscle-Invasive Bladder Cancer Patients

Le Xu, Jiejie Xu, Shengming Jin, 2022, Annals of Surgical Oncology.

Identification and validation of dichotomous immune subtypes based on intratumoral immune cells infiltration in clear cell renal cell carcinoma patients

B. Dai, Le Xu, Hongyu Zhang, 2020, Journal for ImmunoTherapy of Cancer.

Prognostic value of vascular mimicry in patients with urothelial carcinoma of the bladder after radical cystectomy

Le Xu, Yuan Chang, Jiejie Xu, 2016, Oncotarget.

Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma

Le Xu, Yuan Chang, Jiejie Xu, 2016, Oncotarget.

CXC chemokine receptor 2 is associated with postoperative recurrence and survival of patients with non-metastatic clear-cell renal cell carcinoma.

Yuan-feng Yang, Le Xu, Yuan Chang, 2015, European journal of cancer.

Poor clinical outcomes and immunoevasive contexture in SIRPα+ tumor-associated macrophages enriched muscle-invasive bladder cancer patients.

Le Xu, Yuan Chang, Jiejie Xu, 2021, Urologic oncology.

CCR8 blockade primes anti-tumor immunity through intratumoral regulatory T cells destabilization in muscle-invasive bladder cancer

B. Dai, Le Xu, Hongyu Zhang, 2020, Cancer Immunology, Immunotherapy.

P2X7 receptor predicts postoperative cancer-specific survival of patients with clear-cell renal cell carcinoma

Yuan-feng Yang, Le Xu, Yuan Chang, 2015, Cancer science.

CD103+CD8+ tissue-resident memory T cell infiltration predicts clinical outcome and adjuvant therapeutic benefit in muscle-invasive bladder cancer

Y. Zhu, Le Xu, Jiejie Xu, 2022, British Journal of Cancer.

Long noncoding RNA DLX6-AS1 promotes cell growth and invasiveness in bladder cancer via modulating the miR-223-HSP90B1 axis

Le Xu, Chen Fang, Wei He, 2019, Cell cycle.

Prognostic Significance of p21-activated Kinase 6 Expression in Patients with Clear Cell Renal Cell Carcinoma

Le Xu, Jiejie Xu, Haiou Liu, 2014, Annals of Surgical Oncology.

Tip60 is associated with resistance to X‐ray irradiation in prostate cancer

Le Xu, Chen Fang, Wei He, 2017, FEBS open bio.

Impact of an Altered PROX1 Expression on Clinicopathology, Prognosis and Progression in Renal Cell Carcinoma

Le Xu, Lian Chen, Youhua Xie, 2014, PloS one.

Clinical significance of tumor-derived IL-1β and IL-18 in localized renal cell carcinoma: Associations with recurrence and survival.

Le Xu, Guo-min Wang, Jiejie Xu, 2015, Urologic oncology.

Clinical predictors of lymph node metastasis and survival rate in papillary thyroid microcarcinoma: analysis of 3607 patients at a single institution.

Le Xu, Jiadong Wang, Yanan Xu, 2018, The Journal of surgical research.

High Expression of Colony-Stimulating Factor 1 Receptor Associates with Unfavorable Cancer-Specific Survival of Patients with Clear Cell Renal Cell Carcinoma

Le Xu, Yuan Chang, Jiejie Xu, 2016, Annals of Surgical Oncology.

Expression of IL-4 and IL-13 predicts recurrence and survival in localized clear-cell renal cell carcinoma.

Le Xu, Yuan Chang, Lian Chen, 2015, International journal of clinical and experimental pathology.

IL-33 is associated with unfavorable postoperative survival of patients with clear-cell renal cell carcinoma

Yuan-feng Yang, Le Xu, Yuan Chang, 2016, Tumor Biology.

Galectin-8 predicts postoperative recurrence of patients with localized T1 clear cell renal cell carcinoma.

Le Xu, Jiejie Xu, Haiou Liu, 2015, Urologic oncology.

Prognostic significance of ubiquinol-cytochrome c reductase hinge protein expression in patients with clear cell renal cell carcinoma.

Le Xu, Yuan Chang, Jiejie Xu, 2016, American journal of cancer research.

Integrating angiogenesis signature and tumor mutation burden for improved patient stratification in immune checkpoint blockade therapy for muscle-invasive bladder cancer.

Y. Zhu, Le Xu, Jiejie Xu, 2023, Urologic oncology.

Gender disparities in clinical outcomes of urothelial carcinoma linked to X chromosome geneKDM6Amutation

Le Xu, Jiejie Xu, Yu Zhu, 2023, BMJ Oncology.

Integrative score based on CDK6, PD-L1 and TMB predicts response to platinum-based chemotherapy and PD-1/PD-L1 blockade in muscle-invasive bladder cancer

Le Xu, Jiejie Xu, Yu Zhu, 2024, British journal of cancer.

Notch1 predicts recurrence and survival of patients with clear-cell renal cell carcinoma after surgical resection.

Le Xu, Lian Chen, Jiejie Xu, 2015, Urology.