Chengguang Zhao

发表

Yuan Zhang, Yangyang Fu, Lihuang Su, 2020, Definitions.

Flubendazole Elicits Antitumor Effects by Inhibiting STAT3 and Activating Autophagy in Non-small Cell Lung Cancer

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2021, Frontiers in Cell and Developmental Biology.

Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy

Jiayuh Lin, Hui Xiao, Jia Wei, 2017, PloS one.

Synthesis of mono-carbonyl analogues of curcumin and their effects on inhibition of cytokine release in LPS-stimulated RAW 264.7 macrophages.

Chengguang Zhao, Xiaokun Li, G. Liang, 2010, Bioorganic & medicinal chemistry.

Acid-responsive nanoparticles as a novel oxidative stress-inducing anticancer therapeutic agent for colon cancer

Lehe Yang, Chengguang Zhao, Zhongxiang Xiao, 2019, International journal of nanomedicine.

Telocinobufagin Has Antitumor Effects in Non-Small-Cell Lung Cancer by Inhibiting STAT3 Signaling.

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2022, Journal of natural products.

Synthesis, structure, and bioevaluation of 2,5-bis(arylmethenyl)cyclopentanones

Jian Xiao, Chengguang Zhao, Xiaokun Li, 2008, Journal of Asian natural products research.

(2E,5E)-2,5-Bis(2-bromobenzylidene)cyclopentanone

Chengguang Zhao, Guang Liang, Xiaokun Li, 2007 .

Rhein sensitizes human colorectal cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Y. Zhuang, Lehe Yang, Chengguang Zhao, 2019, OncoTargets and therapy.

Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model

Chengguang Zhao, P. Zou, G. Liang, 2015, Drug design, development and therapy.

Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway

Lehe Yang, Chengguang Zhao, Conghui Liu, 2021, Aging.

Dissecting the Role of the FGF19-FGFR4 Signaling Pathway in Cancer Development and Progression

Chengguang Zhao, Xiaokun Li, Yuepiao Cai, 2020, Frontiers in Cell and Developmental Biology.

A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis

Wei Xu, Chengguang Zhao, G. Liang, 2016, Scientific Reports.

Synthesis and anti-inflammatory evaluation of novel mono-carbonyl analogues of curcumin in LPS-stimulated RAW 264.7 macrophages.

Chengguang Zhao, Xiaokun Li, G. Liang, 2010, European journal of medicinal chemistry.

Crystal structure of ortho-(2e,5e) - 2,5-bis(2-methoxy-benzylidene)cyclopentanone,C21H20O3

Chengguang Zhao, Guang Liang, Yi Huang, 2009 .

Exploration and synthesis of curcumin analogues with improved structural stability both in vitro and in vivo as cytotoxic agents.

Jian Xiao, Chengguang Zhao, Xiaokun Li, 2009, Bioorganic & medicinal chemistry.

Crystal structure of ortho-(2E,5E)-2,5-bis(2-methoxybenzylidene) cyclopentanone, C21H20O3

Chengguang Zhao, Guang Liang, Yi Huang, 2009 .

FGF/FGFR signaling: From lung development to respiratory diseases.

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2021, Cytokine & growth factor reviews.

Novel Regulatory Factors and Small-Molecule Inhibitors of FGFR4 in Cancer

Chengguang Zhao, Jiandong Zhu, Jifa Li, 2021, Frontiers in Pharmacology.

nifuratel , a novel sTaT 3 inhibitor with potent activity against human gastric cancer cells

Jiayuh Lin, Chengguang Zhao, Yuepiao Cai, 2017 .

Acetylshikonin exerts anti-tumor effects on non-small cell lung cancer through dual inhibition of STAT3 and EGFR.

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Acetyl-bufalin shows potent efficacy against non-small-cell lung cancer by targeting the CDK9/STAT3 signalling pathway

Y. Zhuang, Lehe Yang, Chengguang Zhao, 2020, British Journal of Cancer.

Alantolactone promotes ER stress‐mediated apoptosis by inhibition of TrxR1 in triple‐negative breast cancer cell lines and in a mouse model

Chengguang Zhao, P. Zou, G. Liang, 2019, Journal of cellular and molecular medicine.

Cyy260, a novel small molecule inhibitor, suppresses non-small cell lung cancer cell growth via JAK2/STAT3 pathway.

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2021, American journal of cancer research.

Gracillin shows potent efficacy against colorectal cancer through inhibiting the STAT3 pathway

Lehe Yang, Chengguang Zhao, Zhiping Li, 2020, Journal of cellular and molecular medicine.

Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2022, Journal of Translational Medicine.

Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2019, Journal of experimental & clinical cancer research : CR.

Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway

Chengguang Zhao, G. Liang, R. Jin, 2016, OncoTargets and therapy.

Effect of the isoflavone corylin from cullen corylifolium on colorectal cancer growth, by targeting the STAT3 signaling pathway.

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Cinobufagin suppresses colorectal cancer growth via STAT3 pathway inhibition.

Mengsi Cai, Chengguang Zhao, Xiaokun Li, 2021, American journal of cancer research.

Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs).

Chengguang Zhao, G. Liang, Zhiguo Liu, 2013, Current pharmaceutical design.

GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma.

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2022, Pharmacological research.

Flubendazole demonstrates valid antitumor effects by inhibiting STAT3 and activating autophagy

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2019, Journal of Experimental & Clinical Cancer Research.

Cynaropicrin Shows Antitumor Progression Potential in Colorectal Cancer Through Mediation of the LIFR/STATs Axis

Sisi Xiao, Lehe Yang, Chengguang Zhao, 2020, Frontiers in Cell and Developmental Biology.

Molecular Carcinogenesis

Yangyang Fu, Lihuang Su, Mengsi Cai, 2019 .

Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism.

Jiayuh Lin, Chengguang Zhao, G. Liang, 2016, Trends in pharmacological sciences.

Hypocrellin A exerts antitumor effects by inhibiting the FGFR1 signaling pathway in non-small cell lung cancer.

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

miR-196b-5p–mediated downregulation of TSPAN12 and GATA6 promotes tumor progression in non-small cell lung cancer

C. Croce, M. Fassan, Sisi Xiao, 2020, Proceedings of the National Academy of Sciences.

Feedback activation of EGFR is the main cause for STAT3 inhibition-irresponsiveness in pancreatic cancer cells

Jiayuh Lin, Lehe Yang, Chengguang Zhao, 2020, Oncogene.

Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells

Jiayuh Lin, Hui Xiao, Chengguang Zhao, 2015, Oncotarget.

Osthole inhibits triple negative breast cancer cells by suppressing STAT3

Chengguang Zhao, G. Liang, O. Wang, 2018, Journal of Experimental & Clinical Cancer Research.

Nifuratel, a novel STAT3 inhibitor with potent activity against human gastric cancer cells

Bin Zhou, Jiayuh Lin, Chengguang Zhao, 2017, Cancer management and research.

Targeting cyclin-dependent kinase 9 in cancer therapy

Chengguang Zhao, Le Yang, Yili Shen, 2021, Acta Pharmacologica Sinica.

Novel activators and small-molecule inhibitors of STAT3 in cancer.

Jiayuh Lin, Lehe Yang, Chengguang Zhao, 2019, Cytokine & growth factor reviews.

Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes

Mengsi Cai, Sisi Xiao, Lehe Yang, 2019, Journal of cellular and molecular medicine.

Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2019, Cancer management and research.

The emerging role of the piRNA/PIWI complex in respiratory tract diseases

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2023, Respiratory Research.

Alantolactone sensitizes human pancreatic cancer cells to EGFR inhibitors through the inhibition of STAT3 signaling

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2019, Molecular carcinogenesis.

Discovery and identification of new non-ATP competitive FGFR1 inhibitors with therapeutic potential on non-small-cell lung cancer.

Chengguang Zhao, Xiaokun Li, J. Ji, 2014, Cancer letters.

Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents

Chengguang Zhao, G. Liang, Zhe Wang, 2014, Drug design, development and therapy.

Aminocyanopyridines as anti‐lung cancer agents by inhibiting the STAT3 pathway

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2019, Molecular carcinogenesis.

Emerging Roles of Ubiquitin-Specific Protease 25 in Diseases

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2021, Frontiers in Cell and Developmental Biology.

Design, synthesis, and biological evaluation of indazole derivatives as selective and potent FGFR4 inhibitors for the treatment of FGF19-driven hepatocellular cancer.

Yongheng Chen, Chengguang Zhao, Yuepiao Cai, 2021, European journal of medicinal chemistry.

AT7519 against lung cancer via the IL6/STAT3 signaling pathway.

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2022, Biochemical and biophysical research communications.

L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway

Jiayuh Lin, Lehe Yang, Chengguang Zhao, 2018, Cancer management and research.

L 61 H 46 shows potent efficacy against human pancreatic cancer through inhibiting STAT 3 pathway

Jiayuh Lin, Chengguang Zhao, G. Liang, 2018 .

Pectolinarigenin Suppresses Pancreatic Cancer Cell Growth by Inhibiting STAT3 Signaling

Chengguang Zhao, Lingyi Shi, Hailun Zheng, 2017 .

Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer

Bin Zhou, Chengguang Zhao, G. Liang, 2017, OncoTargets and therapy.

niclosamide inhibition of sTaT 3 synergizes with erlotinib in human colon cancer

Chengguang Zhao, G. Liang, Zhiguo Liu, 2017 .

Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells

Chengguang Zhao, G. Liang, H. Ye, 2016, Drug design, development and therapy.

Da0324, an inhibitor of nuclear factor-κB activation, demonstrates selective antitumor activity on human gastric cancer cells

Chengguang Zhao, G. Liang, H. Ye, 2016, Drug design, development and therapy.

Pharmacological targeting of MTHFD2 suppresses NSCLC via the regulation of ILK signaling pathway.

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Titin Mutation Is Associated With Tumor Mutation Burden and Promotes Antitumor Immunity in Lung Squamous Cell Carcinoma

Chengguang Zhao, Liangxing Wang, Xiaoying Huang, 2021, Frontiers in Cell and Developmental Biology.

Synthesis and biological evaluation of acetylenic chalcones as novel anti-inflammatory agents.

Chengguang Zhao, G. Liang, Jianmin Zhou, 2015, Medicinal chemistry.

Gracillin relieves pulmonary fibrosis by suppressing the STAT3 axis.

Lehe Yang, Chengguang Zhao, Xiaoying Huang, 2023, Journal of ethnopharmacology.

A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells

Guang Liang, Yi Zhang, Yan Hu, 2017, Anti-cancer drugs.

Molecular Carcinogenesis

Lehe Yang, Chengguang Zhao, Liangxing Wang, 2019 .

Correlation between RNA N6-methyladenosine and ferroptosis in cancer: current status and prospects

Lehe Yang, Chengguang Zhao, Jiandong Zhu, 2024, Frontiers in cell and developmental biology.

Demethylzeylasteral exerts potent efficacy against non-small-cell lung cancer via the P53 signaling pathway

Lehe Yang, Chengguang Zhao, Haiyang Zhao, 2024, Translational oncology.

CDK4/6 inhibitors in lung cancer: current practice and future directions

Lehe Yang, Chengguang Zhao, Haiyang Zhao, 2024, European Respiratory Review.

Solamargine improves the therapeutic efficacy of anti-PD-L1 in lung adenocarcinoma by inhibiting STAT1 activation.

Lehe Yang, Chengguang Zhao, Xiaona Xie, 2024, Phytomedicine : international journal of phytotherapy and phytopharmacology.