H. Niu

发表

Deciphering Protein Kinase Specificity through Large-scale Analysis of Materials Supplemental Deciphering Protein Kinase Specificity through Large-scale Analysis of Yeast Phosphorylation Site Motifs

Bruce Stillman, Hugo Y. K. Lam, Philip M. Kim, 2010 .

Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms

P. Sung, H. Niu, H. Klein, 2014, Nature.

Concentration-Dependent Exchange of Replication Protein A on Single-Stranded DNA Revealed by Single-Molecule Imaging

P. Sung, E. Greene, H. Niu, 2014, PloS one.

Structural basis for the multi-activity factor Rad5 in replication stress tolerance

Jun Yu, H. Niu, H. Deng, 2021, Nature communications.

Biochemical mechanism of DSB end resection and its regulation.

P. Sung, H. Niu, Patrick Sung, 2015, DNA repair.

DNA double-strand break processing: the beginning of the end.

P. Sung, H. Niu, Steven J Raynard, 2008, Genes & development.

Apn2 Resolves Blocked 3’ Ends and Suppresses Top1-Induced Mutagenesis at Genomic rNMP Sites.

H. Niu, Sang Eun Lee, E. Shim, 2019, Nature Structural & Molecular Biology.

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes

J. Loparo, M. Arkin, P. Sung, 2019, Microbial cell.

Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast.

B. Futcher, Chao Zhang, K. Shokat, 2008, Genes & development.

NUCLEOSOME DYNAMICS REGULATE DNA PROCESSING

P. Sung, C. Peterson, H. Niu, 2013, Nature Structural &Molecular Biology.

Regulation of meiotic recombination via Mek1-mediated Rad54 phosphorylation.

S. Gygi, K. Shokat, P. Sung, 2009, Molecular cell.

Mechanistic insights into the multiple activities of the Rad5 family of enzymes.

H. Niu, Miaomiao Shen, S. Xiang, 2022, Journal of molecular biology.

Avoidance of rNMP-induced mutations via RNaseH2 and Srs2-Exo1 dependent mechanisms

P. Sung, H. Niu, H. Klein, 2014, Nature.

Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble

J. Trinidad, H. Niu, G. Ira, 2022, Nature communications.

Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection

P. Sung, P. Thibault, P. Billon, 2018, Proceedings of the National Academy of Sciences.

Regulation of Exo1-mediated DNA end resection

P. Sung, H. Niu, J. Daley, 2015 .

Multiplicity of DNA end resection machineries in chromosome break repair.

P. Sung, H. Niu, Steven J Raynard, 2009, Genes & development.

Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein.

P. Sung, H. Niu, S. Longerich, 2011, DNA repair.

DNA duplex recognition activates Exo1 nuclease activity

H. Niu, Jiangchuan Shen, Yuxi Li, 2019, The Journal of Biological Chemistry.

meiotic recombination in yeast Cdc 28 Clb 5 ( CDKS ) and Cdc 7 Dbf 4 ( DDK ) collaborate to initiate data

B. Futcher, Chao Zhang, K. Shokat, 2008 .

Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast.

P. Sung, E. Greene, H. Niu, 2019, Molecular cell.

Multifaceted role of the Topo IIIα–RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection

P. Sung, H. Niu, Xiaoyu Xue, 2014, Nucleic acids research.

Metal-mediated diradical tuning for DNA replication arrest via template strand scission

H. Niu, Chun-Hsing Chen, Quan Wang, 2017, Proceedings of the National Academy of Sciences.

Phosphorylation of the Synaptonemal Complex Protein Zip1 Regulates the Crossover/Noncrossover Decision during Yeast Meiosis

Danny E. Miller, Huilin Zhou, H. Niu, 2015, PLoS biology.

Partner choice during meiosis is regulated by Hop1-promoted dimerization of Mek1.

Bridget L. Baumgartner, H. Niu, N. M. Hollingsworth, 2005, Molecular biology of the cell.

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

P. Sung, H. Niu, G. Ira, 2011, Nature Structural &Molecular Biology.

A novel role of the Dna2 translocase function in DNA break resection.

P. Sung, H. Niu, G. Ira, 2017, Genes & development.

Restriction of replication fork regression activities by a conserved SMC complex.

P. Sung, H. Niu, C. Wyman, 2014, Molecular cell.

Molecular Cell Smc 5-Smc 6 Restrains Mph 1 in DNA Fork Processing

P. Sung, H. Niu, C. Wyman, 2014 .

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae

Rohit Prakash, Dongqing Liu, P. Sung, 2010, Nature.

A PRC2-independent function for EZH2 in regulating rRNA 2′-O methylation and IRES-dependent translation

L. Fazli, E. Schaeffer, S. Kalantry, 2021, Nature Cell Biology.

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

Anna Malkova, P. Sung, A. Malkova, 2013, Nature.

Mek1 Kinase Is Regulated To Suppress Double-Strand Break Repair between Sister Chromatids during Budding Yeast Meiosis

S. Gygi, D. Moazed, H. Niu, 2007, Molecular and Cellular Biology.

Roles of DNA helicases in the mediation and regulation of homologous recombination.

P. Sung, H. Niu, J. Daley, 2013, Advances in experimental medicine and biology.

Investigations of Homologous Recombination Pathways and Their Regulation

P. Sung, H. Niu, Youngho Kwon, 2013, The Yale journal of biology and medicine.

Inhibition of DNA2 nuclease as a therapeutic strategy targeting replication stress in cancer cells

G. Peng, P. Sung, Surinder Kumar, 2017, Oncogenesis.

DNA Sequence Alignment by Microhomology Sampling during Homologous Recombination

P. Sung, E. Greene, H. Niu, 2015, Cell.

Overcoming natural replication barriers: differential helicase requirements

R. Anand, S. Mirkin, P. Sung, 2011, Nucleic acids research.

Molecular mechanism of resolving trinucleotide repeat hairpin by helicases.

P. Sung, S. Myong, H. Niu, 2015, Structure.

RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals

M. Gorospe, Y. Pommier, W. Shen, 2016, Nucleic acids research.

Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks

P. Sung, H. Niu, Patrick Sung, 2016, PLoS biology.

Roles of DNA helicases and Exo1 in the avoidance of mutations induced by Top1-mediated cleavage at ribonucleotides in DNA

P. Sung, H. Niu, H. Klein, 2016, Cell cycle.

Structure of Rad5 provides insights into its role in tolerance to replication stress

H. Niu, Nalini Dhingra, Xiaolan Zhao, 2021, Molecular & cellular oncology.

Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair*

P. Sung, C. Peterson, S. Grigoryev, 2017, The Journal of Biological Chemistry.

Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection*

P. Sung, H. Niu, Patrick Sung, 2015, The Journal of Biological Chemistry.

Synthetic viability genomic screening defines Sae2 function in DNA repair

Thomas M. Keane, D. Adams, T. Keane, 2015, The EMBO journal.

Protein dynamics during presynaptic complex assembly on individual ssDNA molecules

P. Sung, E. Greene, H. Niu, 2014, Nature Structural &Molecular Biology.

Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble

J. Trinidad, H. Niu, G. Ira, 2022, Nature Communications.

Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection

Xuewen Pan, P. Sung, H. Niu, 2016, Nucleic acids research.

Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.

H. Niu, H. Klein, Hengyao Niu, 2016, FEMS yeast research.

Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1

P. Sung, H. Niu, Xiaolan Zhao, 2016, Genes & development.

Selective modulation of the functions of a conserved DNA motor by a histone fold complex

P. Sung, H. Niu, Xiaolan Zhao, 2015, Genes & development.