M. Schwarz

发表

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

Barbara Kappes, Didier Leroy, Matthias K Schwarz, 2009, Biochemistry.

Importance of Phosphoinositide 3-Kinase γ in the Host Defense against Pneumococcal Infection

K. Preissner, W. Seeger, T. Welte, 2007 .

Multi-faceted strategies to combat disease by interference with the chemokine system.

M. Schwarz, C. Power, A. Proudfoot, 2005, Trends in immunology.

Pharmacology of (2S,4Z)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2′-methyl[1,1′-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a New Potent and Selective Nonpeptide Antagonist of the Oxytocin Receptor

C. Giachetti, M. Schwarz, A. Scheer, 2003, Journal of Pharmacology and Experimental Therapeutics.

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

S. Korsmeyer, C. Hetz, J. Martinou, 2012, The Journal of Biological Chemistry.

Genetic and Pharmacological Targeting of Phosphoinositide 3-Kinase-&ggr; Reduces Atherosclerosis and Favors Plaque Stability by Modulating Inflammatory Processes

C. Rommel, E. Hirsch, J. Salles, 2008, Circulation.

Anti-chemokine small molecule drugs: a promising future?

M. Schwarz, C. Power, A. Proudfoot, 2010, Expert opinion on investigational drugs.

Solid-phase synthesis of 1,5-benzodiazepin-2-ones

M. Gallop, M. Schwarz, D. Tumelty, 1998 .

Arrest of preterm labor in rat and mouse by an oral and selective nonprostanoid antagonist of the prostaglandin F2alpha receptor (FP).

M. Schwarz, A. Scheer, A. Chollet, 2007, American journal of obstetrics and gynecology.

Chemokines as drug targets

M. Schwarz, C. Power, A. Proudfoot, 2007 .

2.14 – Ginkgolide Biosynthesis

M. Schwarz, D. Arigoni, 1999 .

Importance of phosphoinositide 3-kinase gamma in the host defense against pneumococcal infection.

K. Preissner, W. Seeger, T. Welte, 2007, American journal of respiratory and critical care medicine.

Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.

G. Bernardinelli, Y. Filinchuk, C. Giachetti, 2008, Journal of medicinal chemistry.

Recent developments in modulating chemokine networks

M. Schwarz, T. Wells, 1999 .

Solid-phase synthesis of substituted benzimidazoles

M. Schwarz, M. Needels, K. Cao, 1999 .

Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis

Emilio Hirsch, Didier Leroy, C. Rommel, 2005, Nature Medicine.

Solid-Phase Synthesis of 3,5-Disubstituted 2,3-Dihydro-1,5-benzothiazepin-4(5H)-ones

M. Gallop, M. Schwarz, D. Tumelty, 1999 .

Molecular Shape Diversity of Combinatorial Libraries: A Prerequisite for Broad Bioactivity

Wolfgang H. B. Sauer, Matthias K. Schwarz, M. Schwarz, 2003, J. Chem. Inf. Comput. Sci..

Solid-phase synthesis of substituted 1-phenyl-2-aminomethyl-benzimidazoles and 1-phenyl-2-thiomethyl-benzimidazoles

M. Schwarz, M. Needels, D. Tumelty, 1998 .

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.

C. Rommel, M. Camps, Jasna Klicic, 2006, Journal of medicinal chemistry.

Interfering with chemokine networks--the hope for new therapeutics.

M. Schwarz, T. Wells, 1999, Current opinion in chemical biology.

Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists.

C. Giachetti, M. Schwarz, A. Scheer, 2005, Journal of medicinal chemistry.

The p110δ crystal structure uncovers mechanisms for selectivity and potency of novel PI3K inhibitors

Yi Liu, Kevan M. Shokat, Fabrice Gorrec, 2009, Nature chemical biology.

Investigation of the 3-hydroxyvalerate content and degree of crystallinity of P3HB-co-3HV cast films using Raman spectroscopy

M. Schwarz, H. Langowski, V. Jost, 2017 .

Glycosaminoglycan analogs as a novel anti-inflammatory strategy

M. Teixeira, J. Shaw, M. Schwarz, 2012, Front. Immun..

Chemokine inhibition--why, when, where, which and how?

C. Rommel, H. Ji, T. Ruckle, 2004, Biochemical Society transactions.

The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms.

W. Eisenreich, A. Bacher, M. Zenk, 1998, Chemistry & biology.

PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

D. F. Barber, D. Barber, C. Rommel, 2005, Nature Medicine.

New therapeutics that modulate chemokine networks

Timothy N. C. Wells, Matthias K. Schwarz, M. Schwarz, 2002, Nature Reviews Drug Discovery.

PI3Kγ inhibition: towards an 'aspirin of the 21st century'?

C. Rommel, M. Schwarz, Christian Rommel, 2006, Nature Reviews Drug Discovery.

The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Fabrice Gorrec, Simon Miller, Kevan M Shokat, 2010, Nature chemical biology.

the p 110 structure : mechanisms for selectivity and potency of new pI ( 3 ) K inhibitors

K. Shokat, C. Rommel, D. Le, 2010 .

Terpen-Biosynthese in Ginkgo biloba

M. Schwarz, 1994 .

PI3Kgamma inhibition: towards an 'aspirin of the 21st century'?

Matthias K Schwarz, C. Rommel, M. Schwarz, 2006, Nature reviews. Drug discovery.

Bax Channel Inhibitors Prevent Mitochondrion-mediated Apoptosis and Protect Neurons in a Model of Global Brain Ischemia*

S. Korsmeyer, C. Hetz, J. Martinou, 2005, Journal of Biological Chemistry.

Preterm labour: an overview of current and emerging therapeutics.

M. Schwarz, P. Page, 2003, Current medicinal chemistry.

Silicon-containing carbene complexes 16. Intramolecular agostic stabilization versus nucleophilic addition to the 16-electron carbene complex (CO)4(L)WC(NMe2)SiPh2Me

U. Schubert, M. Schwarz, 1994 .

Corrigendum: The p110[delta] structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

K. Shokat, Roger L. Williams, S. Miller, 2010 .

Corrigendum: The p110[delta] structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

K. Shokat, Roger L. Williams, S. Miller, 2010 .