Ž. Skok

发表

Synthesis and evaluation of anticancer activity of new 9-acridinyl amino acid derivatives.

J. Rupar, V. Dobričić, J. Grahovac, 2020, RSC medicinal chemistry.

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.

C. Pál, T. Révész, Ž. Skok, 2019, European journal of medicinal chemistry.

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

C. Stevenson, D. Lawson, Ž. Skok, 2020, ACS medicinal chemistry letters.

Synthesis and biological evaluation of hybrid quinolone-based quaternary ammonium antibacterial agents.

Ž. Skok, A. Fallarero, Krzesimir Ciura, 2019, European journal of medicinal chemistry.

Discovery of new ATP-competitive inhibitors of human DNA topoisomerase IIα through screening of bacterial topoisomerase inhibitors.

Ž. Skok, J. Ilaš, T. Tomašič, 2020, Bioorganic chemistry.

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

C. Pál, T. Révész, Ž. Skok, 2020, Pharmaceutics.

Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity

C. Pál, Ž. Skok, J. Ilaš, 2019, ChemMedChem.

Rational design of balanced dual-targeting antibiotics with limited resistance

C. Pál, T. Révész, B. Kintses, 2020, PLoS biology.

Dual inhibitors of human DNA topoisomerase II and other cancer-related targets.

Ž. Skok, J. Ilaš, Nace Zidar, 2020, Journal of medicinal chemistry.

New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.

C. Pál, Ž. Skok, J. Ilaš, 2018, European journal of medicinal chemistry.

Second generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors.

C. Pál, R. Enriz, Ž. Skok, 2020, Future medicinal chemistry.

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus

Guido V. Janssen, C. Pál, L. Pardo, 2023, Journal of medicinal chemistry.

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Guido V. Janssen, B. Birnir, C. Stevenson, 2023, Journal of medicinal chemistry.

New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.

C. Pál, T. Révész, Ž. Skok, 2021, European journal of medicinal chemistry.

Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.

G. Keserű, Ž. Skok, J. Ilaš, 2018, Bioorganic & medicinal chemistry letters.

Selective DNA Gyrase Inhibitors: Multi-Target in Silico Profiling with 3D-Pharmacophores

Ž. Skok, J. Ilaš, S. Pajk, 2021, Pharmaceuticals.

Design, synthesis and biological evaluation of novel DNA gyrase inhibitors and their siderophore mimic conjugates.

Ž. Skok, J. Ilaš, T. Tomašič, 2019, Bioorganic chemistry.

ATP-competitive inhibitors of human DNA topoisomerase IIα with improved antiproliferative activity based on N-phenylpyrrolamide scaffold.

Ž. Skok, J. Ilaš, T. Tomašič, 2023, European journal of medicinal chemistry.