C. Looi

M. A. Mohd, C. Looi, M. Mustafa, 2012, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Octa-Arginine Mediated Delivery of Wild-Type Lnk Protein Inhibits TPO-Induced M-MOK Megakaryoblastic Leukemic Cell Growth by Promoting Apoptosis

S. Futaki, C. Looi, S. Takaki, 2011, PloS one.

In vitro anti-oxidant and anti-cancer activity of methanolic extract from Sanchezia speciosa leaves.

W. Wong, C. Looi, M. Paydar, 2013, Pakistan journal of biological sciences : PJBS.

Cinnamomum cassia Suppresses Caspase-9 through Stimulation of AKT1 in MCF-7 Cells but Not in MDA-MB-231 Cells

W. Wong, C. Looi, M. Kanthimathi, 2015, PloS one.

T‐cell receptor signaling induces proximal Runx1 transactivation via a calcineurin–NFAT pathway

W. Wong, C. Looi, M. Satake, 2014, European journal of immunology.

Renal targeting potential of a polymeric drug carrier, poly-l-glutamic acid, in normal and diabetic rats

L. Kiew, L. Chung, W. Wong, 2017, International journal of nanomedicine.

Chronic Inflammatory Diseases at Secondary Sites Ensuing Urogenital or Pulmonary Chlamydia Infections

W. Wong, C. Looi, H. C. Cheong, 2020, Microorganisms.

Analgesic, anti-inflammatory and NF-κB inhibitory activity of aerial parts of Cestrum diurnum

W. Wong, C. Looi, S. Uddin, 2020, Clinical Phytoscience.

Simulation of Deep Eutectic Solvents' Interaction with Membranes of Cancer Cells using COSMO-RS.

M. Hashim, M. Hayyan, W. Wong, 2020, The journal of physical chemistry. B.

Antidiabetic and Antioxidant Properties of Alkaloids from Catharanthus roseus (L.) G. Don

W. Wong, C. Looi, M. Mustafa, 2013, Molecules.

Multiple Players in the Mechanical Control of T Cell Quiescence

W. Wong, C. Looi, A. F. Neama, 2017 .

Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study.

W. Wong, C. Looi, M. Mustafa, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Boldine suppresses dextran sulfate sodium-induced mouse experimental colitis: NF-κB and IL-6/STAT3 as potential targets.

C. Looi, M. Mustafa, A. Pandurangan, 2016, BioFactors.

Runx1 Deficiency in CD4+ T Cells Causes Fatal Autoimmune Inflammatory Lung Disease Due to Spontaneous Hyperactivation of Cells

M. Fukumoto, M. Kurokawa, W. Wong, 2012, The Journal of Immunology.

Suppression of cell division-associated genes by Helicobacter pylori attenuates proliferation of RAW264.7 monocytic macrophage cells

W. Wong, C. Looi, M. Loke, 2015, Scientific Reports.

A Comprehensive Review of the Evolution of Insulin Development and Its Delivery Method

G. Sethi, W. Wong, C. Looi, 2022, Pharmaceutics.

Preparation of graphene oxide/dendrimer hybrid carriers for delivery of doxorubicin

L. Kiew, Hong-Boon Lee, L. Chung, 2015 .

Paracrine IL-6 signaling mediates the effects of pancreatic stellate cells on epithelial-mesenchymal transition via Stat3/Nrf2 pathway in pancreatic cancer cells.

A. Masamune, W. Wong, C. Looi, 2017, Biochimica et biophysica acta. General subjects.

Chlamydiaceae: Diseases in Primary Hosts and Zoonosis

W. Wong, C. Looi, H. C. Cheong, 2019, Microorganisms.

β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivo.

W. Wong, C. Looi, S. Mohan, 2014, Journal of ethnopharmacology.

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition

W. Wong, C. Looi, A. Arya, 2012, Evidence-based complementary and alternative medicine : eCAM.

CPAF, HSP60 and MOMP antigens elicit pro-inflammatory cytokines production in the peripheral blood mononuclear cells from genital Chlamydia trachomatis-infected patients.

B. Arulanandam, Rishein Gupta, W. Wong, 2019, Immunobiology.

Prevalence of plasmid-bearing and plasmid-free Chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia

B. Arulanandam, W. Wong, C. Looi, 2016, BMC microbiology.

Erratum: prevalence of plasmid-bearing and plasmid-free chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia

B. Arulanandam, Rishein Gupta, W. Wong, 2016, BMC Microbiology.

Interleukin-17A Secreted from the Lung–infiltrating T Helper 17 Cells Renders Protective Immunity to Pulmonary Cryptococcus neoformans Infection

W. Wong, C. Looi, P. Chong, 2018, bioRxiv.

Immune Checkpoint Molecules and Glucose Metabolism in HIV-Induced T Cell Exhaustion

W. Wong, C. Looi, K. Cheng, 2022, Biomedicines.

Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice

C. Looi, M. E. Norhaizan, A. Pandurangan, 2015, Drug design, development and therapy.

Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis.

W. Wong, C. Looi, H. C. Cheong, 2022, Cellular immunology.

Zika Virus Vaccine: The Current State of Affairs and Challenges Posed by Antibody-Dependent Enhancement Reaction.

W. Wong, C. Looi, H. C. Cheong, 2022, Viral immunology.

Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats

C. Looi, M. Abdulla, Z. Mohamed, 2014, BMC Complementary and Alternative Medicine.

Synthesis, Characterization, and Anticancer Activity of New Quinazoline Derivatives against MCF-7 Cells

C. Looi, M. Abdulla, N. Abdul Majid, 2014, TheScientificWorldJournal.

Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways

W. Wong, C. Looi, M. Mustafa, 2013, BMC Complementary and Alternative Medicine.

Extract of Woodfordia fruticosa flowers ameliorates hyperglycemia, oxidative stress and improves β-cell function in streptozotocin-nicotinamide induced diabetic rats.

M. A. Mohd, C. Looi, M. Mustafa, 2015, Journal of ethnopharmacology.

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.

Sunil K. Panigrahi, M. Ramachandra, C. Looi, 2013, Bioorganic & medicinal chemistry letters.

Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling

W. Wong, C. Looi, J. Vadivelu, 2022, Journal of immunology research.

Innate Immunity Crosstalk with Helicobacter pylori: Pattern Recognition Receptors and Cellular Responses

W. Wong, C. Looi, Y. Y. Cheok, 2022, International journal of molecular sciences.

Laevifins A-G, clerodane diterpenoids from the Bark of Croton oblongus Burm.f.

A. N. Aziz, C. Looi, N. Ismail, 2018, Phytochemistry.

Cytotoxic Constituents from the Rhizomes of Curcuma zedoaria

C. Looi, Syarifah Nur Syed Abdul Rahman, K. Awang, 2014, TheScientificWorldJournal.

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds.

A. Bishayee, G. Sethi, K. Ahn, 2016, Seminars in cancer biology.

Vindogentianine, a hypoglycemic alkaloid from Catharanthus roseus (L.) G. Don (Apocynaceae).

W. Wong, C. Looi, M. Mustafa, 2015, Fitoterapia.

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

G. Sethi, W. Wong, C. Looi, 2019, Cells.

Natural indole butyrylcholinesterase inhibitors from Nauclea officinalis.

C. Looi, M. Mustafa, M. Litaudon, 2015, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Cyclodextrin- and dendrimer-conjugated graphene oxide as a nanocarrier for the delivery of selected chemotherapeutic and photosensitizing agents.

L. Kiew, Hong-Boon Lee, L. Chung, 2018, Materials science & engineering. C, Materials for biological applications.

Apoptotic effect of novel Schiff Based CdCl2(C14H21N3O2) complex is mediated via activation of the mitochondrial pathway in colon cancer cells

C. Looi, H. Karimian, M. Abdulla, 2015, Scientific Reports.

Nickel(II) Complex of Polyhydroxybenzaldehyde N4-Thiosemicarbazone Exhibits Anti-Inflammatory Activity by Inhibiting NF-κB Transactivation

W. Wong, C. Looi, M. Mustafa, 2014, PloS one.

A Schiff Base-Derived Copper (II) Complex Is a Potent Inducer of Apoptosis in Colon Cancer Cells by Activating the Intrinsic Pathway

C. Looi, H. Karimian, M. Abdulla, 2014, TheScientificWorldJournal.

Synthesis of Apoptotic New Quinazolinone-Based Compound and Identification of its Underlying Mitochondrial Signalling Pathway in Breast Cancer Cells.

S. Khalifa, H. El‐Seedi, C. Looi, 2015, Current pharmaceutical design.

Corrigendum: Apoptotic effect of novel Schiff Based CdCl2(C14H21N3O2) complex is mediated via activation of the mitochondrial pathway in colon cancer cells

C. Looi, H. Karimian, M. Abdulla, 2015, Scientific Reports.

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

B. Goh, G. Sethi, Xiaoyun Dai, 2017, Oncotarget.

Anti-diabetic effects of Centratherum anthelminticum seeds methanolic fraction on pancreatic cells, β-TC6 and its alleviating role in type 2 diabetic rats.

M. A. Mohd, C. Looi, M. Mustafa, 2012, Journal of ethnopharmacology.

Induction of Apoptosis in Human Breast Cancer Cells via Caspase Pathway by Vernodalin Isolated from Centratherum anthelminticum (L.) Seeds

W. Wong, C. Looi, M. Mustafa, 2013, PloS one.

Natural deep eutectic solvents: cytotoxic profile

M. Hayyan, W. Wong, C. Looi, 2016, SpringerPlus.

Identification of active extracts of Curcuma zedoaria and their real- time cytotoxic activities on ovarian cancer cells and HUVEC cells

M. A. Mohd, C. Looi, A. Arya, 2017 .

Unraveling the cytotoxicity and metabolic pathways of binary natural deep eutectic solvent systems

M. Hashim, M. Hayyan, W. Wong, 2017, Scientific Reports.

Subditine, a New Monoterpenoid Indole Alkaloid from Bark of Nauclea subdita (Korth.) Steud. Induces Apoptosis in Human Prostate Cancer Cells

W. Wong, C. Looi, M. Mustafa, 2014, PloS one.

Phenylpropanoids isolated from Piper sarmentosum Roxb. induce apoptosis in breast cancer cells through reactive oxygen species and mitochondrial-dependent pathways.

W. Wong, C. Looi, K. Awang, 2018, Chemico-biological interactions.

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

G. Sethi, W. Wong, C. Looi, 2019, Front. Oncol..

Acylphenols and dimeric acylphenols from Myristica maxima Warb.

C. Looi, M. Litaudon, K. Awang, 2016, Fitoterapia.

Lung–infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection

W. Wong, C. Looi, P. Chong, 2018, BMC Immunology.

Triclosan Demonstrates Synergic Effect with Amphotericin B and Fluconazole and Induces Apoptosis-Like Cell Death in Cryptococcus neoformans

W. Wong, C. Looi, Komathy Munusamy, 2016, Front. Microbiol..

Centratherum anthelminticum (L.) Kuntze a potential medicinal plant with pleiotropic pharmacological and biological activities.

W. Wong, C. Looi, A. Arya, 2013 .

The Role of Smoothened-Dependent and -Independent Hedgehog Signaling Pathway in Tumorigenesis

W. Wong, C. Looi, A. Arya, 2021, Biomedicines.

A cell-based screening system for anti-influenza A virus agents

C. Looi, W. Ng, Chee-Kwee Ea, 2015, Scientific Reports.

Pharmacological Activities and Chemical Constituents of Ferula szowitsiana DC

W. Wong, C. Looi, M. Paydar, 2013 .

An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment

W. Wong, C. Looi, J. Vadivelu, 2021, Microorganisms.

Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma

A. Bishayee, G. Sethi, C. Looi, 2017, Targeted Oncology.

Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

W. Wong, C. Looi, M. Mustafa, 2016, Journal of Experimental & Clinical Cancer Research.

Targeting of tubulin polymerization and induction of mitotic blockage by Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) in human cervical cancer HeLa cell

W. Wong, C. Looi, M. Mustafa, 2016, Journal of experimental & clinical cancer research : CR.

An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer

C. Looi, Z. Mohamed, M. Alshawsh, 2016, International journal of medical sciences.

Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo

C. Looi, M. Mustafa, A. Arya, 2015, Journal of experimental & clinical cancer research : CR.

Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44+/CD24−/low): an in vitro study

Maryam Firoozi, Aditya Arya, C. Looi, 2015, Drug design, development and therapy.

Transcriptomic and Genomic Approaches for Unravelling Candida albicans Biofilm Formation and Drug Resistance—An Update

W. Wong, C. Looi, V. Yong, 2018, Genes.

The Microbiome and Irritable Bowel Syndrome – A Review on the Pathophysiology, Current Research and Future Therapy

W. Wong, C. Looi, V. Yong, 2019, Front. Microbiol..

Applications of deep eutectic solvents in biotechnology and bioengineering-Promises and challenges.

Mohd Ali Hashim, Maan Hayyan, Adeeb Hayyan, 2017, Biotechnology advances.

Defining the Role of GLI/Hedgehog Signaling in Chemoresistance: Implications in Therapeutic Approaches

W. Wong, C. Looi, S. Fung, 2021, Cancers.

Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification

A. Masamune, C. Looi, Yuanhong Wu, 2016, Oncotarget.

Comparison of Isolation, Expansion and Cryopreservation Techniques to Produce Stem Cells from Human Exfoliated Deciduous teeth (SHED) with better Regenerative Potential.

Q. H. Looi, C. Looi, P. Chong, 2020, Current stem cell research & therapy.

Immune Recognition versus Immune Evasion Systems in Zika Virus Infection

W. Wong, C. Looi, K. Tan, 2023, Biomedicines.

Non-toxic nature of chebulinic acid on biochemical, hematological and histopathological analysis in normal Sprague Dawley rats

C. Looi, A. Arya, M. Waqas, 2021, Toxicological Research.

The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.

K. Nakayama, Motomi Osato, M. Kurokawa, 2015, Molecular immunology.

Vincristine-resistant Kasabach–Merritt phenomenon successfully treated with low-dose radiotherapy

C. Looi, Mika Watanabe, S. Tsuchiya, 2011, International journal of hematology.

Evaluation of cytotoxic and chemotherapeutic properties of boldine in breast cancer using in vitro and in vivo models

W. Wong, C. Looi, M. Mustafa, 2014, Drug design, development and therapy.

(6E,10E) Isopolycerasoidol and (6E,10E) Isopolycerasoidol Methyl Ester, Prenylated Benzopyran Derivatives from Pseuduvaria monticola Induce Mitochondrial-Mediated Apoptosis in Human Breast Adenocarcinoma Cells

M. A. Mohd, W. Wong, C. Looi, 2015, PloS one.

Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms.

C. Looi, N. Esa, A. Pandurangan, 2015, International immunopharmacology.

Temporal proteomic profiling of Chlamydia trachomatis–infected HeLa‐229 human cervical epithelial cells

B. Arulanandam, Rishein Gupta, W. Wong, 2016, Proteomics.

Podoplanin Drives Motility of Active Macrophage via Regulating Filamin C During Helicobacter pylori Infection

W. Wong, C. Looi, J. Vadivelu, 2021, Frontiers in Immunology.

Prevalence, antimicrobial susceptibility and virulotyping of Listeria species and Listeria monocytogenes isolated from open-air fish markets

W. Wong, C. Looi, S. Ismail, 2015, BMC Microbiology.

In vitro antioxidant, PTP-1B inhibitory effects and in vivo hypoglycemic potential of selected medicinal plants

M. A. Mohd, W. Wong, C. Looi, 2013 .

A Systematic Review of Molecular Hydrogen Therapy in Cancer Management

C. Looi, C. Yeong, E. H. Wong, 2023, Asian Pacific journal of cancer prevention : APJCP.

Recent Development of Nanomaterials for Transdermal Drug Delivery

G. Sethi, W. Wong, C. Looi, 2023, Biomedicines.

Current Development of Chemical Penetration Enhancers for Transdermal Insulin Delivery

M. Hayyan, W. Wong, C. Looi, 2023, Biomedicines.

Recent Advancement of Medical Patch for Transdermal Drug Delivery

G. Sethi, W. Wong, C. Looi, 2023, Medicina.

Influx of podoplanin‐expressing inflammatory macrophages into the genital tract following Chlamydia infection

B. Arulanandam, Rishein Gupta, W. Wong, 2023, Immunology and cell biology.

Prevalence, antimicrobial susceptibility and virulotyping of Listeria species and Listeria monocytogenes isolated from open-air fish markets

W. Wong, C. Looi, S. Ismail, 2015, BMC Microbiology.

Corrigendum: The Microbiome and Irritable Bowel Syndrome – A Review on the Pathophysiology, Current Research and Future Therapy

W. Wong, C. Looi, V. Yong, 2019, Frontiers in Microbiology.

Persea declinata (Bl.) Kosterm Bark Crude Extract Induces Apoptosis in MCF-7 Cells via G0/G1 Cell Cycle Arrest, Bcl-2/Bax/Bcl-xl Signaling Pathways, and ROS Generation

W. Wong, C. Looi, M. Paydar, 2014, Evidence-based complementary and alternative medicine : eCAM.

The chemopreventive potential of Curcuma purpurascens rhizome in reducing azoxymethane-induced aberrant crypt foci in rats

C. Looi, M. Abdulla, Z. Mohamed, 2015, Drug design, development and therapy.

Erratum: prevalence of plasmid-bearing and plasmid-free chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia

B. Arulanandam, Rishein Gupta, W. Wong, 2016, BMC Microbiology.

Chlamydia Infection Remodels Host Cell Mitochondria to Alter Energy Metabolism and Subvert Apoptosis

W. Wong, C. Looi, H. C. Cheong, 2023, Microorganisms.

Chlamydia trachomatis plasmid-encoding Pgp3 protein induces secretion of distinct inflammatory signatures from HeLa cervical epithelial cells

B. Arulanandam, Rishein Gupta, W. Wong, 2023, BMC Microbiology.

Upregulation of insulin secretion and downregulation of pro-inflammatory cytokines, oxidative stress and hyperglycemia in STZ-nicotinamide-induced type 2 diabetic rats by Pseuduvaria monticola bark extract.

W. Wong, C. Looi, A. Arya, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Current advances of nanocellulose application in biomedical field.

W. Wong, C. Looi, Y. L. Kong, 2023, Carbohydrate research.

Phytometabolites Targeting the Warburg Effect in Cancer Cells: A Mechanistic Review.

G. Sethi, W. Wong, C. Looi, 2017, Current drug targets.

Prevalence of plasmid-bearing and plasmid-free Chlamydia trachomatis infection among women who visited obstetrics and gynecology clinics in Malaysia

B. Arulanandam, W. Wong, C. Looi, 2016, BMC Microbiology.

gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BalB/c mice

C. Looi, M. E. Norhaizan, Nooshin Mohebali, 2015 .

gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BalB/c mice

C. Looi, M. E. Norhaizan, Nooshin Mohebali, 2015 .

Tualang and Kelulut Honey Reduced Lipopolysaccharides-stimulated Inflammatory Responses of Microglia

C. Looi, Y. Keong, Kaiyuan Tan, 2023, Malaysian Journal of Medicine and Health Sciences.