K. Hua

发表

Lectin CGL from the sea mussel Crenomytilus grayanus induces Burkitt's lymphoma cells death via interaction with surface glycan.

A. Kuzmich, O. Chernikov, I. Chikalovets, 2017, International journal of biological macromolecules.

Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome

Y. K. Rao, K. Hua, Wen‐Yu Lin, 2018, Front. Immunol..

Composition and Antipathogenic Activities of the Twig Essential Oil of Chamaecyparis formosensis from Taiwan

K. Hua, Y. Su, E. I. Wang, 2012, Natural product communications.

Reishi immuno‐modulation protein induces interleukin‐2 expression via protein kinase‐dependent signaling pathways within human T cells

K. Hua, H. Hsu, J. Hsu, 2008, Journal of cellular physiology.

Accelerated and Severe Lupus Nephritis Benefits From M1, an Active Metabolite of Ginsenoside, by Regulating NLRP3 Inflammasome and T Cell Functions in Mice

K. Hua, C. Chu, Feng-Cheng Liu, 2019, Front. Immunol..

Phagocytosis enhancement, endotoxin tolerance, and signal mechanisms of immunologically active glucuronoxylomannan from Auricularia auricula-judae.

Shih-Hsiung Wu, K. Hua, Feng-Ling Yang, 2020, International journal of biological macromolecules.

Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling.

Shui-Tein Chen, K. Hua, Shang-Tzen Chang, 2008, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cytokine Expression via TLR4-Modulated Extract of Reishi Polysaccharides Induces

Chi‐Huey Wong, K. Hua, Chun-Hung Lin, 2012 .

Protein Kinase Signaling Pathways Cytokine Expression via TLR 4-Modulated Extract of Reishi Polysaccharides Induces

Chi‐Huey Wong, K. Hua, Chun-Hung Lin, 2004 .

Immunostimulatory bioactivity of algal polysaccharides from Chlorella pyrenoidosa activates macrophages via Toll-like receptor 4.

N. Jeyashoke, K. Hua, Yuanda Song, 2010, Journal of agricultural and food chemistry.

Study on the antiinflammatory activity of essential oil from leaves of Cinnamomum osmophloeum.

K. Hua, Ju-Yun Liu, Shang-Tzen Chang, 2005, Journal of agricultural and food chemistry.

NSC828779 Alleviates Renal Tubulointerstitial Lesions Involving Interleukin-36 Signaling in Mice

I-Lin Tsai, K. Hua, A. Wu, 2021, Cells.

NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy

C. Lo, K. Hua, C. Chu, 2017, Scientific Reports.

IgA nephropathy model in mice via activating NrF 2 pathway , and inhibiting T cells and NLRP 3 inflammasome

K. Hua, Jia-Ming Chang, Yi-Ping Chuang, 2013 .

SPAK plays a pathogenic role in IgA nephropathy through the activation of NF-κB/MAPKs signaling pathway.

K. Hua, Shih-Hua Lin, S. Yang, 2016, Free radical biology & medicine.

High glucose increases nitric oxide generation in lipopolysaccharide-activated macrophages by enhancing activity of protein kinase C-α/δ and NF-κB

K. Hua, Chen-Lung Ho, Tzu-Hua Wu, 2012, Inflammation Research.

Heme oxygenase‐1 mediates the anti‐inflammatory effect of Curcumin within LPS‐stimulated human monocytes

K. Hua, L. Chao, H. Hsu, 2008, Journal of cellular physiology.

Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory Activity

O. Chernikov, K. Hua, Wen‐Yu Lin, 2022, Frontiers in Immunology.

The Unusual Lipid A Structure and Immunoinhibitory Activity of LPS from Marine Bacteria Echinicola pacifica KMM 6172T and Echinicola vietnamensis KMM 6221T

O. Chernikov, K. Hua, A. Molinaro, 2021, Microorganisms.

Activity Dependence of a Novel Lectin Family on Structure and Carbohydrate-Binding Properties

O. Chernikov, I. Chikalovets, V. Molchanova, 2019, Molecules.

Citral Is Renoprotective for Focal Segmental Glomerulosclerosis by Inhibiting Oxidative Stress and Apoptosis and Activating Nrf2 Pathway in Mice

K. Hua, Ann Chen, Jia-Ming Chang, 2013, PloS one.

Carboxylic and O-acetyl moieties are essential for the immunostimulatory activity of glucuronoxylomannan: a novel TLR4 specific immunostimulator from Auricularia auricula-judae.

Shih-Hsiung Wu, K. Hua, Feng-Ling Yang, 2018, Chemical communications.

Synthesis of the trisaccharide repeating unit of capsular polysaccharide from Klebsiella pneumoniae

Shih-Hsiung Wu, K. Hua, Y. Lam, 2019, Tetrahedron Letters.

A GalNAc/Gal-specific lectin modulates immune responses via toll-like receptor 4 independently of carbohydrate-binding ability.

J. Liao, Shih-Hsiung Wu, K. Hua, 2021, Chemical communications.

Xenon blunts NF-κB/NLRP3 inflammasome activation and improves acute onset of accelerated and severe lupus nephritis in mice.

Hailin Zhao, D. Ma, K. Hua, 2020, Kidney international.

Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesions.

K. Hua, C. Chu, Y. Hsu, 2019, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Cf‐02, a novel benzamide‐linked small molecule, blunts NF‐κB activation and NLRP3 inflammasome assembly and improves acute onset of accelerated and severe lupus nephritis in mice

D. Mukhopadhyay, K. Hua, Y. Hsu, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Accelerated, severe lupus nephritis benefits from treatment with honokiol by immunoregulation and differentially regulating NF‐κB/NLRP3 inflammasome and sirtuin 1/autophagy axis

K. Hua, Feng-Cheng Liu, Ann Chen, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

K. Hua, H. Sytwu, Feng-Cheng Liu, 2015, Arthritis Research & Therapy.

3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling

K. Hua, K. Su, Ya-Ping Chen, 2014, BMC Complementary and Alternative Medicine.

Neuroprotection by freshwater clam extract against the neurotoxin MPTP in C57BL/6 mice

K. Hua, Wei-Jung Chen, Chai-ching Lin, 2017, Neuroscience Letters.

Composition, in Vitro Anti-inflammatory, Antioxidant and Antimicrobial Activities of Essential Oils from Leaf and Twig Parts of Cupressus Cashmeriana

K. Hua, Chen-Lung Ho, K. Hsu, 2015, Natural product communications.

Effect of Fermented Products Produced by Bacillus licheniformis on the Growth Performance and Cecal Microbial Community of Broilers under Coccidial Challenge

K. Hua, Wei-Jung Chen, Yeong-Hsiang Cheng, 2021, Animals : an open access journal from MDPI.

Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome

Y. K. Rao, K. Hua, Ann Chen, 2019, Scientific Reports.

Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy

K. Hua, Ming-Cheng Chen, Ann Chen, 2015, Journal of cellular physiology.

Bacillus licheniformis-Fermented Products Reduce Diarrhea Incidence and Alter the Fecal Microbiota Community in Weaning Piglets

K. Hua, Wei-Jung Chen, Yeong-Hsiang Cheng, 2019, Animals : an open access journal from MDPI.

Eucalyptus essential oils inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through reducing MAPK and NF-κB pathways

K. Hua, Lan-hui Li, Chen-Lung Ho, 2020, BMC Complementary Medicine and Therapies.

Nano Modification of Antrodia Cinnamomea Exhibits Anti-Inflammatory Action and Improves the Migratory Potential of Myogenic Progenitors

K. Hua, Joy Thomas, Yu-Hsiang Yu, 2022, Cells.

TLR-independent induction of human monocyte IL-1 by phosphoglycolipids from thermophilic bacteria

Shih-Hsiung Wu, S. Liang, K. Hua, 2008, Glycoconjugate Journal.

The leaves of the seasoning plant Litsea cubeba inhibit the NLRP3 inflammasome and ameliorate dextran sulfate sodium-induced colitis in mice

O. Chernikov, K. Hua, Chun-Hsien Wu, 2022, Frontiers in Nutrition.

Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

Y. Hung, Jeng-Shin Lee, K. Hua, 2014, Diabetologia.

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

K. Hua, Ann Chen, L. Chao, 2012, Inflammation Research.

LCC18, a benzamide‐linked small molecule, ameliorates IgA nephropathy in mice

D. Mukhopadhyay, Yusuke Suzuki, K. Hua, 2020, The Journal of pathology.

Anti-inflammatory bioactivities of honokiol through inhibition of protein kinase C, mitogen-activated protein kinase, and the NF-kappaB pathway to reduce LPS-induced TNFalpha and NO expression.

K. Hua, L. Hung, E. I. Wang, 2010, Journal of agricultural and food chemistry.

A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction

Chi-Hung Lin, O. Chernikov, K. Hua, 2020, Frontiers in Immunology.

Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome

Y. K. Rao, O. Chernikov, K. Hua, 2020, Cells.

A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP

K. Hua, Wei-Jung Chen, Lan-hui Li, 2017, PloS one.

Capsular Polysaccharide Is Involved in NLRP3 Inflammasome Activation by Klebsiella pneumoniae Serotype K1

Shih-Hsiung Wu, K. Hua, Jin-Town Wang, 2015, Infection and Immunity.

Cyclooxygenase‐2 Regulates NLRP3 Inflammasome‐Derived IL‐1β Production

Shih-Hsiung Wu, K. Hua, Ann Chen, 2015, Journal of cellular physiology.

Peroxyauraptenol Inhibits Inflammation and NLRP3 Inflammasome Activation by Inhibiting Reactive Oxygen Species Generation and Preserving Mitochondrial Integrity.

Y. Kuo, K. Hua, L. Chao, 2015, Journal of agricultural and food chemistry.

Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation

Shih-Hsiung Wu, K. Hua, Yu-Liang Yang, 2013, PloS one.

Bamboo Vinegar Decreases Inflammatory Mediator Expression and NLRP3 Inflammasome Activation by Inhibiting Reactive Oxygen Species Generation and Protein Kinase C-α/δ Activation

K. Hua, Ann Chen, S. Ka, 2013, PloS one.

Freshwater Clam Extract Inhibits Inflammatory Responses in LPS-Activated Macrophages by Reducing the Activation of Mitogen-Activated Protein Kinases and NF-κB

K. Hua, Ming-Chung Chen, Wei-Jung Chen, 2012, Natural product communications.

Tris DBA ameliorates IgA nephropathy by blunting the activating signal of NLRP3 inflammasome through SIRT1‐ and SIRT3‐mediated autophagy induction

J. Arbiser, K. Hua, Yi-Shan Tsai, 2020, Journal of cellular and molecular medicine.

An Immunological Polysaccharide from Tremella fuciformis: Essential Role of Acetylation in Immunomodulation

Shih-Hsiung Wu, K. Hua, J. Sheu, 2022, International journal of molecular sciences.

Osthole regulates inflammatory mediator expression through modulating NF-κB, mitogen-activated protein kinases, protein kinase C, and reactive oxygen species.

N. Jeyashoke, Y. Kuo, K. Hua, 2010, Journal of agricultural and food chemistry.

Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis.

Shih-Hsiung Wu, K. Hua, Yi-Lin Chan, 2014, Free radical biology & medicine.

Alkali-soluble polysaccharides of Rhizoclonium riparium alga induce IL-1 gene expression via protein kinase signaling pathways.

Chi‐Huey Wong, Shui-Tein Chen, K. Hua, 2006, Journal of agricultural and food chemistry.

IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis.

K. Hua, C. Chu, Y. Hsu, 2017, Journal of the American Society of Nephrology : JASN.

Essential Oil from the Heartwood of Taiwan fir Ameliorates LPS-induced Inflammatory Response by Inhibiting the Activation of Mitogen-activated Protein Kinase

K. Hua, Chen-Lung Ho, Huan-Wen Chiu, 2014, Natural product communications.

Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected Macrophages

O. Chernikov, K. Hua, Chung-Hua Hsu, 2020, Frontiers in Immunology.

Mechanistic insight into the attenuation of gouty inflammation by Taiwanese green propolis via inhibition of the NLRP3 inflammasome

Yue‐wen Chen, Y. K. Rao, K. Hua, 2018, Journal of cellular physiology.

Affinity-Driven Covalent Modulator of the Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Cascade.

Shih-Hsiung Wu, K. Hua, Chun-ping Lu, 2018, Angewandte Chemie.

Essential Oil from Leaves of Liquidambar formosana Ameliorates Inflammatory Response in Lipopolysaccharide-activated Mouse Macrophages

K. Hua, Chen-Lung Ho, Huan-Wen Chiu, 2014, Natural product communications.

Cyclopeptides with anti-inflammatory activity from seeds of Annona montana.

Y. Wu, F. Chang, Shih-Hsiung Wu, 2008, Journal of natural products.

Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway

K. Hua, S. Yang, Ann Chen, 2013, PloS one.

Optimization of Emulsification Conditions on Ethanol Extract of Taiwanese Green Propolis Using Polysorbate and Its Immunomodulatory Effects in Broilers

Yue‐wen Chen, K. Hua, Chia-Jung Tsai, 2022, Animals : an open access journal from MDPI.

Synthesis and biological evaluation of polyenylpyrrole derivatives as anticancer agents acting through caspases-dependent apoptosis.

Shih-Hsiung Wu, K. Hua, Yu-Liang Yang, 2010, Journal of medicinal chemistry.

Anti-inflammatory activity of sugiol, a diterpene isolated from Calocedrus formosana bark.

K. Hua, Kuo-Ping Chao, Shang-Tzen Chang, 2005, Planta medica.

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome.

Shih-Hsiung Wu, K. Hua, Shih-Hua Lin, 2013, Free radical biology & medicine.

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation.

K. Hua, Hsian-Cheng Chen, S. Yang, 2011, Free radical biology & medicine.

Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response

Wei-Chung Cheng, Katsuhiko Suzuki, K. Hua, 2017, Scientific Reports.

Polysaccharides from Dioscorea batatas induce tumor necrosis factor-alpha secretion via Toll-like receptor 4-mediated protein kinase signaling pathways.

Shih-Hsiung Wu, K. Hua, Yu-Liang Yang, 2008, Journal of agricultural and food chemistry.

Hepatoprotective Effect of Wheat-Based Solid-State Fermented Antrodia cinnamomea in Carbon Tetrachloride-Induced Liver Injury in Rat

K. Hua, Huan-Wen Chiu, Kuo-Feng Hua, 2016, PloS one.