Lidan Zhang

发表

A novel benzothiazole derivative SKLB826 inhibits human hepatocellular carcinoma growth via inducing G2/M phase arrest and apoptosis

Xiaowei Liu, Q. Lei, Lidan Zhang, 2015 .

Discovery of novel N-(5-(tert-butyl)isoxazol-3-yl)-N'-phenylurea analogs as potent FLT3 inhibitors and evaluation of their activity against acute myeloid leukemia in vitro and in vivo.

Q. Lei, Lidan Zhang, Yong Xia, 2015, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents.

Yuquan Wei, Lidan Zhang, Yong Xia, 2013, Bioorganic & medicinal chemistry letters.

Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

Yuquan Wei, Lidan Zhang, Yongxia Zhu, 2016, Scientific Reports.

Synthesis and antitubercular evaluation of 4-carbonyl piperazine substituted 1,3-benzothiazin-4-one derivatives.

Q. Lei, Lidan Zhang, Yongxia Zhu, 2015, Bioorganic & medicinal chemistry letters.

Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway

Lidan Zhang, Han Yang, P. Fu, 2021, Acta Pharmacologica Sinica.

Discovery of indol-6-yl-pyrrolo[2,3-c]pyridin-7-one derivatives as bromodomain-containing protein 4 (BRD4) inhibitors for the treatment of kidney fibrosis.

Lidan Zhang, Liang Ma, Lifeng Zhao, 2022, European journal of medicinal chemistry.

The discovery of SKLB-0335 as a paralog-selective EZH2 covalent inhibitor.

Lidan Zhang, Yongxia Zhu, Ningyu Wang, 2021, Chemical communications.

Mannosylated liposomes improve therapeutic effects of paclitaxel in colon cancer models

Q. Lei, Lidan Zhang, Yong Xia, 2017, Journal of microencapsulation.

Discovery of imidazo[2,1-b]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents.

Yuquan Wei, Hong Tang, Q. Lei, 2015, Journal of medicinal chemistry.

Discovery of novel polycyclic spiro-fused carbocyclicoxindole-based anticancer agents.

Lidan Zhang, Lifeng Zhao, Xia Zhang, 2017, European journal of medicinal chemistry.

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors.

Yuquan Wei, Sheng-yong Yang, Lidan Zhang, 2014, Bioorganic & medicinal chemistry letters.

N-[(4-Carbamoylphenyl)carbamothioyl]-2,3,4,5-tetrafluorobenzamide

Lidan Zhang, Xuejiao Song, Luoting Yu, 2011, Acta crystallographica. Section E, Structure reports online.

Design, synthesis and biological evaluation of novel C3-functionalized oxindoles as potential Pim-1 kinase inhibitors

Lidan Zhang, Lifeng Zhao, Xiaoyan Wang, 2015 .

Correction: Synthesis and biological evaluation of N -(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents

Lidan Zhang, Tinghong Ye, Yongxia Zhu, 2015 .

Small Molecule TH-39 Potentially Targets Hec1/Nek2 Interaction and Exhibits Antitumor Efficacy in K562 Cells via G0/G1 Cell Cycle Arrest and Apoptosis Induction

Lidan Zhang, Tinghong Ye, Yongxia Zhu, 2016, Cellular Physiology and Biochemistry.

Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity

Lidan Zhang, Yongxia Zhu, Luoting Yu, 2019, Molecular Diversity.

Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors

Lidan Zhang, Xuejiao Song, Ningyu Wang, 2015 .

Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis

Yuquan Wei, Sheng-yong Yang, Q. Lei, 2017, Cell Death & Disease.

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Q. Lei, Lidan Zhang, 2016, Scientific Reports.

Selective inhibition of EZH2 by ZLD10A blocks H3K27 methylation and kills mutant lymphoma cells proliferation.

Q. Lei, Lidan Zhang, Tinghong Ye, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

A novel small-molecule YLT256 inhibits proliferation and induces apoptosis both in vitro and in vivo in solid tumors.

Lidan Zhang, Yong Xia, Tinghong Ye, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Pharmacological Inhibition of EZH2 by ZLD1039 Suppresses Tumor Growth and Pulmonary Metastasis in Melanoma Cells in vitro and in vivo.

Lidan Zhang, Yongxia Zhu, Xuejiao Song, 2023, Biochemical pharmacology.

Piperlongumine Induces Apoptosis in Human Melanoma Cells Via Reactive Oxygen Species Mediated Mitochondria Disruption

Q. Lei, Lidan Zhang, Xuejiao Song, 2018, Nutrition and cancer.

A novel benzothiazinethione analogue SKLB-TB1001 displays potent antimycobacterial activities in a series of murine models.

Yuquan Wei, Lidan Zhang, Ningyu Wang, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

ZLD1122, a novel EZH2 and EZH1 small molecular inhibitor, blocks H3K27 methylation and diffuse large B cell lymphoma cell growth

Q. Lei, Lidan Zhang, Yong Xia, 2016 .

A novel VEGFR inhibitor ZLF-095 with potent antitumor activity and low toxicity

Q. Lei, Lidan Zhang, Xuejiao Song, 2023, Heliyon.

The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model

Yuquan Wei, Lidan Zhang, Yong Xia, 2014, PloS one.

Design, Synthesis, and Biological Evaluation of a Potent Dual EZH2-BRD4 Inhibitor for the Treatment of Some Solid Tumors.

Lidan Zhang, Nian-nian Huang, Ruotian Jiang, 2023, Journal of medicinal chemistry.

A patent review of EZH2 inhibitors from 2017 and beyond

Lidan Zhang, Yongxia Zhu, Huan Feng, 2023, Expert opinion on therapeutic patents.

A new series of HCV inhibitors based on a 2-(thieno[2,3b]pyridin-2-yl)-1,3,4-oxadiazole scaffold

Hong Tang, Lidan Zhang, Yongxia Zhu, 2016 .

Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

Yuquan Wei, Q. Lei, Lidan Zhang, 2016, Scientific Reports.

Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity

Lidan Zhang, Yongxia Zhu, Xin Tao, 2019, Molecular Diversity.

Correction: Inhibition of Stat3 signaling pathway by nifuroxazide improves antitumor immunity and impairs colorectal carcinoma metastasis

Yuquan Wei, Sheng-yong Yang, Q. Lei, 2019, Cell Death and Disease.

Novel small molecules as apoptosis inducers: synthesis, preliminary structure-activity relationships, and in vitro biological evaluation.

Yuquan Wei, Sheng-yong Yang, Lidan Zhang, 2013, Bioorganic & medicinal chemistry letters.

Corrigendum: Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Lidan Zhang, Yong Xia, 2016, Scientific Reports.