Tinghong Ye

发表

A novel benzothiazole derivative SKLB826 inhibits human hepatocellular carcinoma growth via inducing G2/M phase arrest and apoptosis

Xiaowei Liu, Q. Lei, Lidan Zhang, 2015 .

Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis

Qinjie Wu, Yuquan Wei, Tinghong Ye, 2015, Scientific Reports.

SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.

Yuquan Wei, Q. Lei, Yong Xia, 2014, Cancer letters.

Liver Fibrosis: Therapeutic Targets and Advances in Drug Therapy

Tinghong Ye, Yuqin Yao, Zui Tan, 2021, Frontiers in Cell and Developmental Biology.

Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro.

Tinghong Ye, Shuangqing Li, Yongmei Xie, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

An overview of Sirtuins as potential therapeutic target: Structure, function and modulators.

L. Ouyang, Tinghong Ye, Xin Wang, 2019, European journal of medicinal chemistry.

Genetically modified human placenta-derived mesenchymal stem cells with FGF-2 and PDGF-BB enhance neovascularization in a model of hindlimb ischemia

Yuquan Wei, Tinghong Ye, G. Shen, 2015, Molecular medicine reports.

Methylprednisolone Decreases Mitochondria-Mediated Apoptosis and Autophagy Dysfunction in Hepatocytes of Experimental Autoimmune Hepatitis Model via the Akt/mTOR Signaling

Tinghong Ye, Xuefeng Luo, R. Men, 2019, Front. Pharmacol..

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway

Tinghong Ye, Cailing Gan, Hongyao Liu, 2022, Frontiers in Pharmacology.

A novel multikinase inhibitor SKLB‐YTH‐60 ameliorates inflammation and fibrosis in bleomycin‐induced lung fibrosis mouse models

Xiuli Wu, L. Ouyang, Guan Wang, 2021, Cell proliferation.

Cryptotanshinone reverses the epithelial‐mesenchymal transformation process and attenuates bleomycin‐induced pulmonary fibrosis

Tinghong Ye, Yongmei Xie, Yuqin Yao, 2020, Phytotherapy research : PTR.

Design, synthesis and biological evaluation of a series of novel pyrrolo[2,3-d]pyrimidin/pyrazolo[3,4-d]pyrimidin-4-amine derivatives as FGFRs-dominant multi-target receptor tyrosine kinase inhibitors for the treatment of gastric cancer.

L. Ouyang, Tinghong Ye, Cailing Gan, 2022, Bioorganic chemistry.

Complete chloroplast genome sequence of a subtropical tree, Parasassafras confertiflorum (Lauranceae)

Tinghong Ye, Yu Song, Q. Liao, 2018, Mitochondrial DNA. Part B, Resources.

Cholesterol-modified Hydroxychloroquine-loaded Nanocarriers in Bleomycin-induced Pulmonary Fibrosis

Ling Li, Yuquan Wei, Tinghong Ye, 2017, Scientific Reports.

Synthesis and biological evaluation of indazole derivatives as anti-cancer agents

Xiuli Wu, Tinghong Ye, Luoting Yu, 2021, RSC advances.

Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation

Tinghong Ye, Xuelei Ma, Tao Yin, 2013, Journal of Translational Medicine.

Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis

Yong Xia, Tinghong Ye, Q. Xue, 2019, Front. Pharmacol..

Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma

Yi Luo, Tinghong Ye, Yongmei Xie, 2019, Investigational New Drugs.

Punica granatum (pomegranate) peel extract exerts potent antitumor and anti-metastasis activity in thyroid cancer

He He, Tinghong Ye, Fangfang Yang, 2016 .

Targeting fibrosis: mechanisms and clinical trials

Tinghong Ye, H. Cui, Shijie Zhou, 2022, Signal Transduction and Targeted Therapy.

Glucose Metabolism Reprogramming of Regulatory T Cells in Concanavalin A-Induced Hepatitis

Tinghong Ye, R. Men, Chen-Na Huang, 2021, Frontiers in Pharmacology.

Total glucosides of paeony decreases apoptosis of hepatocytes and inhibits maturation of dendritic cells in autoimmune hepatitis.

Tinghong Ye, Xuefeng Luo, R. Men, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The role of natural products in the prevention and treatment of pulmonary fibrosis: a review.

Tinghong Ye, Yuqin Yao, Wenya Yin, 2021, Food & function.

Synthesis and biological evaluation of N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)benzenesulfonamide derivatives as new BET bromodomain inhibitors for anti-hematologic malignancies activities

Tinghong Ye, Yongxia Zhu, Ningyu Wang, 2017, Molecular Diversity.

Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway

Li Yang, R. Aqeilan, Li Yang, 2020, Signal Transduction and Targeted Therapy.

Extravascular Red Blood Cells and Hemoglobin Promote Tumor Growth and Therapeutic Resistance as Endogenous Danger Signals

Yuquan Wei, Tinghong Ye, Xiaoling Liu, 2015, The Journal of Immunology.

The antifibrotic effect and mechanism of a novel tyrosine kinase inhibitor, ZSP1603, in preclinical models of pulmonary fibrosis.

Tinghong Ye, Z-W Liu, yuan yao, 2020, European review for medical and pharmacological sciences.

Comparison of Concanavalin a-Induced Murine Autoimmune Hepatitis Models

Tinghong Ye, R. Men, Xiaoli Fan, 2018, Cellular Physiology and Biochemistry.

Critical roles of conventional dendritic cells in autoimmune hepatitis via autophagy regulation

Tinghong Ye, R. Men, Chen-Na Huang, 2020, Cell Death & Disease.

Discovery and evaluation of phenacrylanilide derivatives as novel potential anti-liver fibrosis agents.

Tinghong Ye, Zui Tan, Taixiong Xue, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel diarylacylhydrazones derivatives for the efficient treatment of idiopathic pulmonary fibrosis.

Tinghong Ye, Guan Wang, Yuqin Yao, 2022, European journal of medicinal chemistry.

Galangin ameliorated pulmonary fibrosis in vivo and in vitro by regulating epithelial-mesenchymal transition.

Tinghong Ye, Yuqin Yao, Yali Li, 2020, Bioorganic & medicinal chemistry.

Mannosylated liposomes improve therapeutic effects of paclitaxel in colon cancer models

Q. Lei, Lidan Zhang, Yong Xia, 2017, Journal of microencapsulation.

Synthesis and biological evaluation of (1,2,4)triazole[4,3-a]pyridine derivatives as potential therapeutic agents for concanavalin A-induced hepatitis.

Yong Xia, Tinghong Ye, Xuejiao Song, 2019, European journal of medicinal chemistry.

Novel thermosensitive hydrogel for preventing formation of abdominal adhesions

C. Gong, Tinghong Ye, B. Shao, 2013, International journal of nanomedicine.

A Novel Small-Molecule YLT205 Induces Apoptosis in Human Colorectal Cells via Mitochondrial Apoptosis Pathway In Vitro and Inhibits Tumor Growth In Vivo

Yong Xia, Tinghong Ye, Yongxia Zhu, 2014, Cellular Physiology and Biochemistry.

Correction: Synthesis and biological evaluation of N -(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents

Lidan Zhang, Tinghong Ye, Yongxia Zhu, 2015 .

YLT192, a Novel, Orally Active Bioavailable Inhibitor of VEGFR2 Signaling with Potent Antiangiogenic Activity and Antitumor Efficacy in Preclinical Models

Yuquan Wei, You-Li Pan, Q. Lei, 2014, Scientific Reports.

Punica granatum (pomegranate) leaves extract induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in non-small cell lung cancer in vitro.

Yi Luo, Tinghong Ye, Fangfang Yang, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Punica granatum (pomegranate) peel extract exerts potent antitumor and anti-metastasis activity in thyroid cancer

He He, Tinghong Ye, Fangfang Yang, 2016 .

Lobaplatin arrests cell cycle progression, induces apoptosis and impairs migration and invasion in B16-F10 melanoma cell line in vitro.

Yuquan Wei, Q. Lei, Tinghong Ye, 2015, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Pectolinarigenin inhibits cell viability, migration and invasion and induces apoptosis via a ROS-mitochondrial apoptotic pathway in melanoma cells

Tinghong Ye, Yali Li, Cailing Gan, 2020, Oncology letters.

Niclosamide-loaded nanoparticles (Ncl-NPs) reverse pulmonary fibrosis in vivo and in vitro

C. Gong, L. Ouyang, Tinghong Ye, 2022, Journal of advanced research.

Emerging targets and potential therapeutic agents in non-alcoholic fatty liver disease treatment.

L. Ouyang, Tinghong Ye, Yongmei Xie, 2020, European journal of medicinal chemistry.

Hinokiflavone induces apoptosis in melanoma cells through the ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion.

G. Wang, Yi Luo, Tinghong Ye, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Small Molecule TH-39 Potentially Targets Hec1/Nek2 Interaction and Exhibits Antitumor Efficacy in K562 Cells via G0/G1 Cell Cycle Arrest and Apoptosis Induction

Lidan Zhang, Tinghong Ye, Yongxia Zhu, 2016, Cellular Physiology and Biochemistry.

Cryptotanshinone induces melanoma cancer cells apoptosis via ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion.

Tinghong Ye, Yongxia Zhu, Luoting Yu, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Discovery of Novel Dual-Target Inhibitor of Bromodomain-Containing Protein 4/Casein Kinase 2 Inducing Apoptosis and Autophagy-Associated Cell Death for Triple-Negative Breast Cancer Therapy.

C. Chiang, L. Ouyang, Guan Wang, 2021, Journal of medicinal chemistry.

Identification and optimization of 3-bromo-N'-(4-hydroxybenzylidene)-4-methylbenzohydrazide derivatives as mTOR inhibitors that induce autophagic cell death and apoptosis in triple-negative breast cancer.

L. Ouyang, Guan Wang, Tian Xu, 2021, European journal of medicinal chemistry.

Epigenetic regulation in fibrosis progress.

Tinghong Ye, Zui Tan, Taixiong Xue, 2021, Pharmacological research.

YLT-11, a novel PLK4 inhibitor, inhibits human breast cancer growth via inducing maladjusted centriole duplication and mitotic defect

Q. Lei, Yong Xia, Tinghong Ye, 2018, Cell Death & Disease.

Natural product pectolinarigenin exhibits potent anti-metastatic activity in colorectal carcinoma cells in vitro and in vivo.

Tinghong Ye, Luoting Yu, Yali Li, 2019, Bioorganic & medicinal chemistry.

Antitumor activity in colorectal cancer induced by hinokiflavone

Tinghong Ye, Fangfang Yang, Yongmei Xie, 2019, Journal of gastroenterology and hepatology.

Synthesis and biological evaluation of (E)-4-(3-arylvinyl-1H-indazol-6-yl)pyrimidin-2-amine derivatives as PLK4 inhibitors for the treatment of breast cancer

Q. Lei, Tinghong Ye, Ningyu Wang, 2017 .

Design and Synthesis of EZH2-Based PROTACs to Degrade the Complex for Targeting the Noncatalytic Activity of EZH2.

Xiuli Wu, Tinghong Ye, Yongxia Zhu, 2021, Journal of medicinal chemistry.

MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

R. Aqeilan, Tinghong Ye, Yong Peng, 2018, Cell Death & Disease.

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Q. Lei, Lidan Zhang, 2016, Scientific Reports.

Roles of Macrophages and Exosomes in Liver Diseases

Li Yang, Tinghong Ye, R. Men, 2020, Frontiers in Medicine.

Selective inhibition of EZH2 by ZLD10A blocks H3K27 methylation and kills mutant lymphoma cells proliferation.

Q. Lei, Lidan Zhang, Tinghong Ye, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The extract from Punica granatum (pomegranate) peel induces apoptosis and impairs metastasis in prostate cancer cells.

Yi Luo, Yong Xia, Tinghong Ye, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Aging Reprograms the Hematopoietic-Vascular Niche to Impede Regeneration and Promote Fibrosis.

C. Esmon, B. Ding, Tinghong Ye, 2020, Cell metabolism.

Repurposing of Antipsychotic Trifluoperazine for Treating Brain Metastasis, Lung Metastasis and Bone Metastasis of Melanoma by Disrupting Autophagy Flux.

Yong Xia, Tinghong Ye, Luoting Yu, 2020, Pharmacological research.

Malignant Pleural Effusion and ascites Induce Epithelial-Mesenchymal Transition and Cancer Stem-like Cell Properties via the Vascular Endothelial Growth Factor (VEGF)/Phosphatidylinositol 3-Kinase (PI3K)/Akt/Mechanistic Target of Rapamycin (mTOR) Pathway*

Yuquan Wei, Sheng-yong Yang, Tinghong Ye, 2016, The Journal of Biological Chemistry.

A Novel Cinnamide YLT26 Induces Breast Cancer Cells Apoptosis via ROS-Mitochondrial Apoptotic Pathway in Vitro and Inhibits Lung Metastasis in Vivo

Yuquan Wei, Mengyao Wang, Yong Xia, 2014, Cellular Physiology and Biochemistry.

A novel small-molecule YLT256 inhibits proliferation and induces apoptosis both in vitro and in vivo in solid tumors.

Lidan Zhang, Yong Xia, Tinghong Ye, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice

Tinghong Ye, Yongmei Xie, Yuqin Yao, 2022, Nutrients.

An oral phenylacrylic acid derivative suppressed hepatic stellate cell activation and ameliorated liver fibrosis by blocking TGF‐β1 signalling

Tinghong Ye, Zui Tan, Taixiong Xue, 2022, Liver international : official journal of the International Association for the Study of the Liver.

Repurposing of the Anti-helminthic Drug Niclosamide to Treat Melanoma and Pulmonary Metastasis via the STAT3 Signaling Pathway.

Xiuli Wu, Yue Wang, Tinghong Ye, 2019, Biochemical pharmacology.

Cationic nanocarriers induce cell necrosis through impairment of Na+/K+-ATPase and cause subsequent inflammatory response

Wei Wang, Chengyu Jiang, Bin Shao, 2015, Cell Research.

Lobaplatin induces BGC-823 human gastric carcinoma cell apoptosis via ROS- mitochondrial apoptotic pathway and impairs cell migration and invasion.

B. Liu, Tinghong Ye, Fangfang Yang, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1

Tinghong Ye, Xifei Yang, Yongmei Xie, 2020, Acta pharmaceutica Sinica. B.

Immunomodulatory Role and Therapeutic Potential of Non-Coding RNAs Mediated by Dendritic Cells in Autoimmune and Immune Tolerance-Related Diseases

Tinghong Ye, Li Yang, Xiaoze Wang, 2021, Frontiers in Immunology.

MicroRNAs in autoimmune liver diseases: from diagnosis to potential therapeutic targets.

Tinghong Ye, R. Men, Xian Xing, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice.

Tinghong Ye, R. Men, Xiaoli Fan, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Nifuroxazide ameliorates pulmonary fibrosis by blocking myofibroblast genesis: a drug repurposing study

L. Ouyang, Guan Wang, Tinghong Ye, 2022, Respiratory Research.

ZLD1122, a novel EZH2 and EZH1 small molecular inhibitor, blocks H3K27 methylation and diffuse large B cell lymphoma cell growth

Q. Lei, Lidan Zhang, Yong Xia, 2016 .

Inhibition of FGFR signaling by PD173074 improves antitumor immunity and impairs breast cancer metastasis

Yuquan Wei, Yong Xia, Tinghong Ye, 2014, Breast Cancer Research and Treatment.

Discovery of the novel Benzo[b]thiophene 1,1-dioxide derivatives as a potent STAT3 inhibitor against idiopathic pulmonary fibrosis.

Tinghong Ye, Taixiong Xue, Cailing Gan, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of 7-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-2,3-dihydro-1H-inden-1-one derivatives as potent FAK inhibitors for the treatment of ovarian cancer.

Tinghong Ye, Yongxia Zhu, Ningyu Wang, 2021, European journal of medicinal chemistry.

Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis

S. Rafii, K. Shido, B. Ding, 2017, Science Translational Medicine.

Inhibition of Stat3 Signaling Pathway by Natural Product Pectolinarigenin Attenuates Breast Cancer Metastasis

Tinghong Ye, Yongmei Xie, Yali Li, 2019, Front. Pharmacol..

Antiangiogenic Therapy Using Sunitinib Combined with Rapamycin Retards Tumor Growth But Promotes Metastasis

Tinghong Ye, G. Shen, Tao Yin, 2014, Translational oncology.

The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model

Yuquan Wei, Lidan Zhang, Yong Xia, 2014, PloS one.

Application and Study of ROCK Inhibitors in Pulmonary Fibrosis: Recent Developments and Future Perspectives.

Tinghong Ye, Taixiong Xue, Cailing Gan, 2023, Journal of medicinal chemistry.

Identify a Blood-Brain Barrier Penetrating Drug-TNB using Zebrafish Orthotopic Glioblastoma Xenograft Model

Tinghong Ye, S. Yao, Xi Huang, 2017, Scientific Reports.

Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator

Yongsheng Wang, Tinghong Ye, Tao Yin, 2016, Scientific Reports.

Cholesterol-modified Hydroxychloroquine-loaded Nanocarriers in Bleomycin-induced Pulmonary Fibrosis

Ling Li, Yuquan Wei, Tinghong Ye, 2017, Scientific Reports.

Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma

Yuquan Wei, Q. Lei, Lidan Zhang, 2016, Scientific Reports.

Critical roles of conventional dendritic cells in autoimmune hepatitis via autophagy regulation

Tinghong Ye, R. Men, Chen-Na Huang, 2020, Cell Death & Disease.

Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis

S. Friedman, B. Ding, Tinghong Ye, 2021, Science Translational Medicine.

MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression

R. Aqeilan, Tinghong Ye, Yong Peng, 2018, Cell Death & Disease.

Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation

Tinghong Ye, R. Men, Jianping Liu, 2018, Canadian journal of gastroenterology & hepatology.

Novel small molecules as apoptosis inducers: synthesis, preliminary structure-activity relationships, and in vitro biological evaluation.

Yuquan Wei, Sheng-yong Yang, Lidan Zhang, 2013, Bioorganic & medicinal chemistry letters.

Niclosamide induces colorectal cancer apoptosis, impairs metastasis and reduces immunosuppressive cells in vivo

Yuquan Wei, Yi Luo, Tinghong Ye, 2016 .

Determination of Enantiomeric Purity of GSK962040 Based on Liquid Chromatography Using Chiral Stationary Phase Combined with a Pre-column Derivatization Procedure

Tinghong Ye, Yongmei Xie, Mengya Liao, 2017, Chromatographia.

Corrigendum: Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Lidan Zhang, Yong Xia, 2016, Scientific Reports.

HPLC Determination of Enantiomeric Purity of Letermovir Based on CHIRALPAK AD.

Tinghong Ye, Xiaolin Zhang, Mengya Liao, 2016, Journal of chromatographic science.

Matrix metalloproteinases inhibitors in idiopathic pulmonary fibrosis: Medicinal chemistry perspectives.

L. Ouyang, Guan Wang, Tinghong Ye, 2021, European journal of medicinal chemistry.

Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation

Xiang Gao, Tinghong Ye, Xuelei Ma, 2013, Journal of Translational Medicine.

Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model

X. Song, Q. Lei, Yong Xia, 2015, Cell Death and Disease.

Identify a Blood-Brain Barrier Penetrating Drug-TNB using Zebrafish Orthotopic Glioblastoma Xenograft Model

Tinghong Ye, S. Yao, Xi Huang, 2017, Scientific Reports.

A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies

Tinghong Ye, Yongxia Zhu, Xuejiao Song, 2013, PloS one.

Dopamine receptor antagonist thioridazine inhibits tumor growth in a murine breast cancer model

Tinghong Ye, G. Shen, Tao Yin, 2015, Molecular medicine reports.