Sunjoo Ahn

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Novel Antimitotic Compounds with Potent In Vitro and In Vivo Antitumor Effects: the Use of Pharmacokinetics, Metabolism, Efficacy, and Toxicity Studies

Sunjoo Ahn, 2010 .

Encapsulation and Enhanced Delivery of Topoisomerase I Inhibitors in Functionalized Carbon Nanotubes

Sunjoo Ahn, Y. Jung, S. Chae, 2018, ACS omega.

Biotransformation of a Novel Antimitotic Agent, I-387, by Mouse, Rat, Dog, Monkey, and Human Liver Microsomes and In Vivo Pharmacokinetics in Mice

Duane D. Miller, Charles B. Duke, J. Dalton, 2011, Drug Metabolism and Disposition.

Microsoft Word-85670376-file00

Duane D. Miller, Charles B. Duke, J. Dalton, 2010 .

Orally Bioavailable Tubulin Antagonists for Paclitaxel-Refractory Cancer

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras.

Sunjoo Ahn, H. S. Kim, Seung-Hyun Jo, 2020, European journal of medicinal chemistry.

Rational Design, Synthesis and Evaluation of Novel C6 ‐Bicycloalkaneimidazole Containing Imidazo[1,2‐ b ]pyridazines for ASK1 Inhibition

Sunjoo Ahn, J. Jang, C. Chae, 2021, Bulletin of the Korean Chemical Society.

Design, Synthesis, and Biological Evaluation of Stable Colchicine Binding Site Tubulin Inhibitors as Potential Anticancer Agents

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2014, Journal of medicinal chemistry.

Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Journal of medicinal chemistry.

Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-Aryl-Thiazole (SMART) and 2-Aryl-4-Benzoyl-Imidazole (ABI) for Improving Oral Bioavailability

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011 .

Biological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitor.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011, Cancer research.

Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-aryl-thiazole and 2-Aryl-4-benzoyl-imidazole for Improving Oral Bioavailability

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011, Drug Metabolism and Disposition.

I-387, a Novel Antimitotic Indole, Displays a Potent In vitro and In vivo Antitumor Activity with Less Neurotoxicity

Duane D. Miller, Charles B. Duke, J. Dalton, 2010, Molecular Cancer Therapeutics.

3-Aryl-1,2,4-oxadiazole Derivatives Active Against Human Rhinovirus.

Sunjoo Ahn, Young-Sik Jung, S. Han, 2018, ACS medicinal chemistry letters.

Zebrafish as a Screening Model for Testing the Permeability of Blood-Brain Barrier to Small Molecules.

Sunjoo Ahn, Dae-Seop Shin, C. Yun, 2017, Zebrafish.

αVβ3-Targeted delivery of camptothecin-encapsulated CNT-cyclic RGD in 2D and 3D cancer cell culture.

S. B. Park, Sunjoo Ahn, Dasol Lee, 2019, Journal of pharmaceutical sciences.

Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming

Eunjoon Kim, Hyojin Kang, Sunjoo Ahn, 2022, Nature Communications.

Development and validation of a liquid chromatography‐tandem mass spectrometry method for pharmacokinetic study of TM‐53, a novel transcriptional coactivator with PDZ‐binding motif (TAZ) modulator

Sunjoo Ahn, M. Bae, J. Song, 2017, Journal of pharmaceutical and biomedical analysis.

A validated UPLC‐MS/MS method for pharmacokinetic study of inflachromene, a novel microglia inhibitor

Sunjoo Ahn, S. K. Kim, M. Bae, 2019, Journal of pharmaceutical and biomedical analysis.

Synthesis and Molecular Modeling Studies of N′-Hydroxyindazolecarboximidamides as Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors

Sunjoo Ahn, Chang Hoon Lee, Jieun K. Jeong, 2017, Molecules.

Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infections

Bin Zhou, Sunjoo Ahn, S. Han, 2022, Archives of pharmacal research.

Inhibitors of Tubulin Assembly Identified through Screening a Compound Library

D. Sackett, M. Phelps, J. Dalton, 2008, Chemical biology & drug design.

Discovery of 4-Aryl-2-benzoyl-imidazoles as tubulin polymerization inhibitor with potent antiproliferative properties.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2013, Journal of medicinal chemistry.

Neurochemical and behavioral analysis by acute exposure to bisphenol A in zebrafish larvae model.

Sunjoo Ahn, Dae-Seop Shin, Kyeong-Ryoon Lee, 2019, Chemosphere.

Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin.

Yan Lu, Ramesh Narayanan, Duane D. Miller, 2010, Journal of mass spectrometry : JMS.

Discovery of a Novel Chemical Scaffold Against Mutant Isocitrate Dehydrogenase 1 (IDH1)

H. Jeong, Sunjoo Ahn, Chi-Hoon Park, 2020, AntiCancer Research.

Flavopiridol Pharmacogenetics: Clinical and Functional Evidence for the Role of SLCO1B1/OATP1B1 in Flavopiridol Disposition

M. Grever, J. Byrd, W. Sadee, 2010, PloS one.

Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera

D. Hwang, Sunhong Kim, B. Park, 2019, Scientific Reports.

Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization.

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011, Bioorganic & medicinal chemistry.

UPLC-MS/MS-based profiling of 31 neurochemicals in the mouse brain after treatment with the antidepressant nefazodone

Sunjoo Ahn, M. Bae, J. Song, 2021 .

Integrative Analyses Reveal the Anticancer Mechanisms and Sensitivity Markers of the Next-Generation Hypomethylating Agent NTX-301

Sunjoo Ahn, Byungho Lim, R. Boohaker, 2023, Cancers.

Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats

Sunjoo Ahn, Yoo-Kyung Song, Kyeong-Ryoon Lee, 2021, Pharmaceutics.

Minor modifications to ceritinib enhance anti-tumor activity in EML4-ALK positive cancer.

H. Jeong, Eun-Young Kim, Sunjoo Ahn, 2016, Cancer letters.

Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2014, PloS one.

LightBBB: computational prediction model of blood-brain-barrier penetration based on LightGBM

Jae Yong Ryu, Myeong-Sang Yu, Bilal Shaker, 2020, Bioinform..

SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function

Y. Bae, Eunjoon Kim, Jinju Han, 2021, EMBO molecular medicine.

Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R.

Sunjoo Ahn, Chi-Hoon Park, H. Jung, 2017, European journal of medicinal chemistry.

Direct endothelial junction restoration results in significant tumor vascular normalization and metastasis inhibition in mice

S. Ha, M. Won, G. Koh, 2014, Oncotarget.

Antibacterial Activity against Clinical Isolates and In Vivo Efficacy of Coralmycins

Sunjoo Ahn, D. Yong, J. Kwak, 2022, Antibiotics.

Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats

Sunjoo Ahn, Kyeong-Ryoon Lee, T. Koo, 2015, Archives of pharmacal research.

Microsoft Word-74812886-file00

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2011 .

Novel 2,4-diaminopyrimidines bearing tetrahydronaphthalenyl moiety against anaplastic lymphoma kinase (ALK): Synthesis, in vitro, ex vivo, and in vivo efficacy studies.

Sunjoo Ahn, Chi-Hoon Park, Minji Lee, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing bicyclic aminobenzazepines for anaplastic lymphoma kinase (ALK) inhibitor.

Sunjoo Ahn, Chi-Hoon Park, Minji Lee, 2015, Bioorganic & medicinal chemistry letters.

PredMS: a random Forest model for predicting metabolic stability of drug candidates in human liver microsomes.

J. H. Lee, Sunjoo Ahn, J. Ryu, 2021, Bioinformatics.

PredPS: Attention-based graph neural network for predicting stability of compounds in human plasma

Sunjoo Ahn, J. Song, W. Jang, 2023, Computational and structural biotechnology journal.

Orally Bioavailable Tubulin Antagonists for Paclitaxel-Refractory Cancer

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer

Duane D. Miller, Charles B. Duke, J. Dalton, 2011, Cancer Chemotherapy and Pharmacology.

Pharmacokinetics, pharmacodynamics and metabolism of a novel anticancer agent for prostate cancer.

Duane D. Miller, Zengrui Wu, J. Dalton, 2012, International journal of oncology.

Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis

Duane D. Miller, J. Dalton, Sunjoo Ahn, 2012, Pharmaceutical Research.

Discovery and synthesis of 1,2,4-oxadiazole derivatives as novel inhibitors of Zika, dengue, Japanese encephalitis, and classical swine fever virus infections

Sunjoo Ahn, S. Han, J. Shin, 2022, Archives of Pharmacal Research.

Pharmacokinetics of tafamidis, a transthyretin amyloidosis drug, in rats

S. Joo, Sunjoo Ahn, Sungwook Choi, 2018, Xenobiotica; the fate of foreign compounds in biological systems.

Differential effects of two phosphodiesterase 4 inhibitors against lipopolysaccharide-induced neuroinflammation in mice

Sunjoo Ahn, J. Chae, Jin-sook Song, 2023, BMC Neuroscience.

Design, Synthesis, and Evaluation of 2,4‐Di(piperidine‐substituted‐anilino)pyrimidine Derivatives as ALK Inhibitors

Sunjoo Ahn, Chi-Hoon Park, H. Jung, 2015 .

Anti-neuroinflammatory Effects and Brain Pharmacokinetic Properties of Selonsertib, an Apoptosis signal-regulating Kinase 1 Inhibitor, in mice

Sunjoo Ahn, J. Song, S. Ji, 2022, Neurochemical Research.

Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats

Sunjoo Ahn, Kyeong-Ryoon Lee, T. Koo, 2015, Archives of Pharmacal Research.

Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid, a novel DGAT-1 inhibitor

Sunjoo Ahn, M. Bae, J. Song, 2014, Xenobiotica; the fate of foreign compounds in biological systems.