L. Tucker

发表

Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells

C. Tse, W. N. Pappano, Qian Zhang, 2014, BMC Cancer.

Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor

Qian Zhang, L. Tucker, Jieyi Wang, 2008, Proceedings of the National Academy of Sciences.

Inhibition of Aurora B kinase sensitizes a subset of human glioma cells to TRAIL concomitant with induction of TRAIL-R2

K. Glaser, O. Shah, L. Tucker, 2009, Cell Death and Differentiation.

Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases.

S. Davidsen, Eric F. Johnson, J. Wilsbacher, 2010, Bioorganic & medicinal chemistry letters.

ABBV-399, a c-Met Antibody–Drug Conjugate that Targets Both MET–Amplified and c-Met–Overexpressing Tumors, Irrespective of MET Pathway Dependence

Kedar S Vaidya, L. Naumovski, Mark G. Anderson, 2016, Clinical Cancer Research.

Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification

Kedar S Vaidya, L. Naumovski, P. Ansell, 2016, BMC Cancer.

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

S. Fesik, Qian Zhang, L. Tucker, 2007, Cancer research.

Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation

S. Davidsen, Qian Zhang, L. Tucker, 2008, Oncogene.

Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases.

Scott A. Erickson, S. Davidsen, K. Swinger, 2010, Bioorganic & medicinal chemistry letters.

A “Prozone-Like” Effect Influences the Efficacy of the Monoclonal Antibody ABT-700 against the Hepatocyte Growth Factor Receptor

Kedar S Vaidya, Mark G. Anderson, W. N. Pappano, 2017, Pharmacology.

Reducing agent-mediated precipitation of high-abundance plasma proteins.

Anita Saraf, Bhawani Singh, P. Jung, 2009, Analytical biochemistry.

Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification

Kedar S Vaidya, L. Naumovski, P. Ansell, 2016, BMC Cancer.

Insulin-like Growth Factor-1 Receptor and ErbB Kinase Inhibitor Combinations Block Proliferation and Induce Apoptosis through Cyclin D1 Reduction and Bax Activation*

S. Davidsen, J. Wilsbacher, Gary T. Wang, 2008, Journal of Biological Chemistry.

Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases.

Scott A. Erickson, S. Davidsen, Eric F. Johnson, 2009, Bioorganic & medicinal chemistry letters.

Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition.

S. Davidsen, P. Richardson, Qian Zhang, 2008, Journal of proteome research.

Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor

Qian Zhang, L. Tucker, Jieyi Wang, 2008, Proceedings of the National Academy of Sciences.