Ling Yang

发表

An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors.

Yan Li, Yinfeng Yang, Jinghui Wang, 2013, Molecular bioSystems.

Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.

Yan Li, Yonghua Wang, Yan Li, 2005, Bioorganic & medicinal chemistry letters.

Interaction mechanism exploration of HEA derivatives as BACE1 inhibitors by in silico analysis.

Yan Li, Jinghui Wang, Ling Yang, 2016, Molecular bioSystems.

Systems pharmacology to decipher the combinational anti-migraine effects of Tianshu formula.

Zhenzhong Wang, W. Xiao, Yan Li, 2015, Journal of ethnopharmacology.

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease.

Xue Xu, Yonghua Wang, Xia Wang, 2013, Journal of ethnopharmacology.

Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice.

Jinan Wang, W. Zhou, Yonghua Wang, 2013, Journal of ethnopharmacology.

Systems Pharmacology Dissection of the Anti-Inflammatory Mechanism for the Medicinal Herb Folium Eriobotryae

Yonghua Wang, Yan Li, Yinfeng Yang, 2015, International journal of molecular sciences.

A Systems-Pharmacology Analysis of Herbal Medicines Used in Health Improvement Treatment: Predicting Potential New Drugs and Targets

Yonghua Wang, Yan Li, Ling Yang, 2013, Evidence-based complementary and alternative medicine : eCAM.

Prediction of the deleterious nsSNPs in ABCB transporters

Yonghua Wang, Yan Li, Ling Yang, 2006, FEBS letters.

Insight into the Structural Features of Pyrazolopyrimidine‐ and Pyrazolopyridine‐based B‐RafV600E Kinase Inhibitors by Computational Explorations

Yan Li, Yinfeng Yang, Jinghui Wang, 2014, Chemical biology & drug design.

Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases.

Wei Zhou, Wei Wang, Bohui Li, 2014, Journal of ethnopharmacology.

Computational Analysis of Structure-Based Interactions for Novel H1-Antihistamines

Yan Li, Yinfeng Yang, Jinghui Wang, 2016, International journal of molecular sciences.

In silico research to assist the investigation of carboxamide derivatives as potent TRPV1 antagonists.

Yan Li, Yinfeng Yang, Jinghui Wang, 2015, Molecular bioSystems.

Profiling the interaction mechanism of indole-based derivatives targeting the HIV-1 gp120 receptor

Yan Li, Yinfeng Yang, Jinghui Wang, 2015 .

In silico profiling the interaction mechanism of 2,5-diketopiperazine derivatives as oxytocin antagonists.

Ling Yang, Jianghe Luo, Yan Li, 2019, Journal of molecular graphics & modelling.

Exploring the structural determinants of novel xanthine derivatives as A2B adenosine receptor antagonists: a computational study

Yan Li, Yinfeng Yang, Yanqiu Pan, 2018, Journal of biomolecular structure & dynamics.

Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT2A Receptor by In Silico Methods

Yan Li, Yinfeng Yang, Jinghui Wang, 2017, Molecules.

Profiling the Interaction Mechanism of Quinoline/Quinazoline Derivatives as MCHR1 Antagonists: An in Silico Method

Yan Li, Jinghui Wang, Shuwei Zhang, 2014, International journal of molecular sciences.

Structure determinants of indolin-2-on-3-spirothiazolidinones as MptpB inhibitors: An in silico study

Zhenzhong Wang, W. Xiao, Yan Li, 2013 .

Exploring the structure determinants of pyrazinone derivatives as PDE5 3HC8 inhibitors: an in silico analysis.

Guohui Li, Yan Li, Jinghui Wang, 2012, Journal of molecular graphics & modelling.

Structural Requirements of N-Substituted Spiropiperidine Analogues as Agonists of Nociceptin/Orphanin FQ Receptor

Guohui Li, Yan Li, Shuwei Zhang, 2011, International journal of molecular sciences.

A 3-D QSAR Study of Catechol-O-Methyltransferase Inhibitors Using CoMFA and CoMSIA

Yonghua Wang, Yan Li, Ling Yang, 2008 .

MDR1 gene polymorphisms and clinical relevance.

Yonghua Wang, Yan Li, Ling Yang, 2006, Yi chuan xue bao = Acta genetica Sinica.

In Silico Identification of Structure Requirement for Novel Thiazole and Oxazole Derivatives as Potent Fructose 1,6-Bisphosphatase Inhibitors

Guohui Li, Yan Li, Mingjuan Ji, 2011, International journal of molecular sciences.

Structural features of falcipain-3 inhibitors: an in silico study.

Yan Li, Yinfeng Yang, Jinghui Wang, 2013, Molecular bioSystems.

Structural Determinants of CX-4945 Derivatives as Protein Kinase CK2 Inhibitors: A Computational Study

Guohui Li, Xia Wang, Yan Li, 2011, International journal of molecular sciences.

The 3D-QSAR and pharmacophore studies of pyrimidine derivatives as HCV replication (replicase) inhibitor

Yan Li, Yinfeng Yang, Jinghui Wang, 2015, Medicinal Chemistry Research.

A Systems Biology Approach to Uncovering Pharmacological Synergy in Herbal Medicines with Applications to Cardiovascular Disease

Xue Xu, Yan Li, Weiyang Tao, 2012, Evidence-based complementary and alternative medicine : eCAM.

A Systems Biology Approach to Understanding the Mechanisms of Action of Chinese Herbs for Treatment of Cardiovascular Disease

Yonghua Wang, Xue Xu, Bohui Li, 2012, International journal of molecular sciences.

A System-Level Investigation into the Mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for Cardiovascular Disease Treatment

Xue Xu, Hongjun Yang, Haiyu Xu, 2012, PloS one.

An in silico approach for screening flavonoids as P-glycoprotein inhibitors based on a Bayesian-regularized neural network

Ling Yang, Yan Li, Yong-Hua Wang, 2005, J. Comput. Aided Mol. Des..

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Wei Zhou, Peng Li, Ling Yang, 2014, Journal of Cheminformatics.

Systems pharmacology uncovers Janus functions of botanical drugs: activation of host defense system and inhibition of influenza virus replication

Yonghua Wang, Xue Xu, Yan Li, 2012, Integrative biology : quantitative biosciences from nano to macro.

RSC_IB_C2IB20204B 1..21

Xue Xu, Xiuxiu Li, Yonghua Wang, 2013 .

Insight into the effects of chiral isomers quinidine and quinine on CYP2D6 inhibition.

Yan Li, Yadong Chen, Chunzhi Ai, 2009, Bioorganic & medicinal chemistry letters.

Systems pharmacology in drug discovery and therapeutic insight for herbal medicines

Chao Huang, Ling Yang, Yan Li, 2014, Briefings Bioinform..

Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction.

Yonghua Wang, Chunli Zheng, Chao Huang, 2013, Journal of ethnopharmacology.

A systematic identification of multiple toxin-target interactions based on chemical, genomic and toxicological data.

Yan Li, Wei Zhou, Chao Huang, 2013, Toxicology.

Comparison of steroid substrates and inhibitors of P-glycoprotein by 3D-QSAR analysis

Yan Li, Yonghua Wang, Yan Li, 2005 .

Impact of Molecular Hydrophobic Field on Passive Diffusion, P–Glycoprotein Active Efflux, and P–Glycoprotein Modulation of Steroids

Yonghua Wang, Yan Li, Shuwei Zhang, 2006 .

Insights from systems pharmacology into cardiovascular drug discovery and therapy

Peng Li, Chao Huang, Ling Yang, 2014, BMC Systems Biology.

pH-dependent channel gating in connexin26 hemichannels involves conformational changes in N-terminus.

Xue Xu, Yonghua Wang, Xia Wang, 2012, Biochimica et biophysica acta.

A novel model to predict O-glycosylation sites using a highly unbalanced dataset

Kun Zhou, Peipei Dong, Ling Yang, 2012, Glycoconjugate Journal.

Inhibition mechanism exploration of quinoline derivatives as PDE10A inhibitors by in silico analysis.

Yan Li, Jinghui Wang, Weimin Gao, 2013, Molecular bioSystems.

Combined 3D-QSAR, Molecular Docking, and Molecular Dynamics Study on Piperazinyl-Glutamate-Pyridines/Pyrimidines as Potent P2Y12 Antagonists for Inhibition of Platelet Aggregation

Ming Hao, Ling Yang, Guohui Li, 2011, J. Chem. Inf. Model..

Investigation of binding features: Effects on the interaction between CYP2A6 and inhibitors

Wei Li, Ling Yang, Yan Li, 2010, J. Comput. Chem..

Classification of Substrates and Inhibitors of P-Glycoprotein Using Unsupervised Machine Learning Approach

Ling Yang, Yan Li, Yong-Hua Wang, 2005, J. Chem. Inf. Model..

A large-scale association study for nanoparticle C60 uncovers mechanisms of nanotoxicity disrupting the native conformations of DNA/RNA

Yan Li, Yonghua Wang, Xia Wang, 2012, Nucleic acids research.

Exploring the structure requirement for PKCθ inhibitory activity of pyridinecarbonitrile derivatives: an in silico analysis.

Yan Li, Guohui Li, Ming Hao, 2012, Journal of molecular graphics & modelling.

Structure Requirements for 4-Aryl-4H-Chromenes as Apoptosis Inducers Using 3D QSAR Methods and Docking Studies

Yonghua Wang, Guohui Li, Yan Li, 2012 .

Insight into the structural requirements of benzimidazole derivatives as interleukin-2 inducible t-cell kinase inhibitors by computational explorations

Yan Li, Yinfeng Yang, Jinghui Wang, 2013 .

Distribution of the functional MDR1 C3435T polymorphism in the Han population of China.

Yonghua Wang, Yan Li, Ling Yang, 2006, Swiss medical weekly.

Investigations into the analysis and modeling of the cytochrome P450 cycle.

Yan Li, Yonghua Wang, Yan Li, 2006, The journal of physical chemistry. B.

Insight into the binding mode and the structural features of the pyrimidine derivatives as human A2A adenosine receptor antagonists

Xia Wang, Ling Yang, Guohui Li, 2014, Biosyst..

Exploring details about structure requirements based on novel CGRP receptor antagonists urethanamide, aspartate, succinate and pyridine derivatives by in silico methods

Yan Li, Jinghui Wang, Shuwei Zhang, 2014 .

Systems approaches and polypharmacology for drug discovery from herbal medicines: an example using licorice.

Jinan Wang, W. Zhou, Yonghua Wang, 2013, Journal of ethnopharmacology.