B. Cao

发表

A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.

M. Moran, J. Li, A. Datti, 2011, Blood.

The mTOR signaling pathway is an emerging therapeutic target in multiple myeloma.

X. Mao, B. Cao, Jie Li, 2014, Current pharmaceutical design.

The ubiquitin-proteasomal system is critical for multiple myeloma: implications in drug discovery.

X. Mao, B. Cao, Biyin Cao, 2011, American journal of blood research.

Theoretical studies on beta and delta isoform-specific binding mechanisms of phosphoinositide 3-kinase inhibitors.

Youyong Li, P. Pan, Dan Li, 2014, Molecular bioSystems.

The Ubiquitin-Proteasomal System and Blood Cancer Therapy

X. Mao, B. Cao, Biyin Cao, 2012 .

A novel PI3K inhibitor displays potent preclinical activity against an androgen-independent and PTEN-deficient prostate cancer model established from the cell line PC3.

X. Mao, B. Cao, Zhao-Peng Liu, 2014, Toxicology letters.

, 3-kinase pathway preclinical efficacy in myeloma and leukemia via phosphoinositide A small-molecule inhibitor of D-cyclin transactivation displays

M. Moran, A. Datti, Jiefei Tong, 2011 .

A novel hedgehog inhibitor for the treatment of hematological malignancies

X. Mao, B. Cao, Xiaohu Zhang, 2018, Anti-cancer drugs.

Inhibition of the deubiquitinase USP9x induces pre-B cell homeobox 1 (PBX1) degradation and thereby stimulates prostate cancer cell apoptosis

G. Sethi, Jinbao Liu, Yan Liu, 2019, The Journal of Biological Chemistry.

The antidepressant amitriptyline shows potent therapeutic activity against multiple myeloma

X. Mao, B. Cao, Xiaoling Du, 2013, Anti-cancer drugs.

Cyproheptadine‐induced myeloma cell apoptosis is associated with inhibition of the PI3K/AKT signaling

X. Mao, B. Cao, Jie Li, 2013, European journal of haematology.

Preparation of S14161 and its analogues and the discovery of 6-bromo-8-ethoxy-3-nitro-2H-chromene as a more potent antitumor agent in vitro.

X. Mao, B. Cao, Xiaoling Du, 2013, Bioorganic & medicinal chemistry letters.

SC06, a novel small molecule compound, displays preclinical activity against multiple myeloma by disrupting the mTOR signaling pathway

X. Mao, B. Cao, Xiaowen Tang, 2015, Scientific Reports.

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis

M. Moran, J. Li, Jiefei Tong, 2017, Journal of Hematology & Oncology.

The ubiquitin ligase HERC4 mediates c-Maf ubiquitination and delays the growth of multiple myeloma xenografts in nude mice.

M. Moran, Jiefei Tong, Guanghui Wang, 2016, Blood.

Targeting the Otub1/c-Maf axis for the treatment of multiple myeloma.

M. Moran, Jiefei Tong, A. Stewart, 2020, Blood.

Proteomic Analysis Revealed the Important Role of Vimentin in Human Cervical Carcinoma HeLa Cells Treated With Gambogic Acid*

Min Yang, Xuan Liu, Wanying Wu, 2015, Molecular & Cellular Proteomics.

Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation.

B. Cao, Runying Wang, Yipeng Wang, 2021, Microbiological research.

Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis

Jinbao Liu, Qi Wang, X. Mao, 2021, Cell Death & Disease.

Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathway

J. Li, X. Mao, B. Cao, 2014, Scientific Reports.

The Class I PI3K inhibitor S14161 induces autophagy in malignant blood cells by modulating the Beclin 1/Vps34 complex.

J. Li, X. Mao, B. Cao, 2017, Journal of pharmacological sciences.

Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization

X. Mao, B. Cao, Jingyu Zhu, 2014, Journal of Hematology & Oncology.

Natural Pesticide Dihydrorotenone Arrests Human Plasma Cancer Cells at the G0/G1 Phase of the Cell Cycle

X. Mao, B. Cao, Jinping Zhang, 2014, Journal of biochemical and molecular toxicology.

Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia

X. Mao, B. Cao, Yueyang Zhong, 2022, The Journal of biological chemistry.

Induction of zinc ﬁ nger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia

X. Mao, B. Cao, Yueyang Zhong, 2022 .

The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor

Qi Wang, X. Mao, B. Cao, 2018, The Journal of Biological Chemistry.

Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway

Qin Lu, Qi Wang, X. Mao, 2018, Front. Pharmacol..

Protein‐phosphotyrosine proteome profiling by superbinder‐SH2 domain affinity purification mass spectrometry, sSH2‐AP‐MS

M. Moran, S. Li, J. Krieger, 2017, Proteomics.

Ubiquitination of the transcription factor c‐maf is mediated by multiple lysine residues (LB188)

M. Moran, Jiefei Tong, X. Mao, 2014, The international journal of biochemistry & cell biology.

Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis

M. Moran, Jiefei Tong, X. Mao, 2017, Cell Death and Disease.

The deubiquitinase USP10 restores PTEN activity and inhibits non–small cell lung cancer cell proliferation

X. Mao, B. Cao, Hui Zheng, 2021, The Journal of biological chemistry.

Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis

Qi Wang, X. Mao, B. Cao, 2021, Cell communication and signaling : CCS.

Anti-bacterial and anti-viral nanchangmycin displays anti-myeloma activity by targeting Otub1 and c-Maf

X. Mao, B. Cao, Depei Wu, 2020, Cell Death & Disease.

The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

M. Moran, Jiefei Tong, X. Mao, 2019, The Journal of Biological Chemistry.

A Promising Combo Gene Delivery System Developed from (3-Aminopropyl)triethoxysilane-Modified Iron Oxide Nanoparticles and Cationic Polymers

Yu Zhang, N. Gu, X. Mao, 2013, Journal of Nanoparticle Research.

Nitroxoline shows antimyeloma activity by targeting the TRIM25/p53 axle

X. Mao, B. Cao, Jun Zhao, 2017, Anti-cancer drugs.

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma

X. Mao, B. Cao, Jingyu Zhu, 2014, Oncotarget.

Interferon-stimulated gene 15 induces cancer cell death by suppressing the NF-κB signaling pathway

X. Mao, B. Cao, Haibin Zhou, 2016, Oncotarget.

The Natural Pesticide Dihydrorotenone Induces Human Plasma Cell Apoptosis by Triggering Endoplasmic Reticulum Stress and Activating p38 Signaling Pathway

J. Li, X. Mao, B. Cao, 2013, PloS one.

A deuterated analog of dasatinib disrupts cell cycle progression and displays anti‐non‐small cell lung cancer activity in vitro and in vivo

X. Mao, B. Cao, Yun Zhao, 2012, International journal of cancer.

An anti-leishmanial thiadiazine agent induces multiple myeloma cell apoptosis by suppressing the nuclear factor kappaB signalling pathway

Z. Zhang, J. Tang, X. Mao, 2013, British Journal of Cancer.

The Antiparasitic Clioquinol Induces Apoptosis in Leukemia and Myeloma Cells by Inhibiting Histone Deacetylase Activity*

Yang Yu, Tingjun Hou, Jingyu Zhu, 2013, The Journal of Biological Chemistry.

The Tricyclic Antidepressant Amitriptyline Inhibits d-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence

S. Trudel, M. Fei, X. Mao, 2011, Molecular Pharmacology.

Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha

Yan Liu, X. Mao, B. Cao, 2017, Oncotarget.

An inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathway

X. Mao, B. Cao, Jingyu Zhu, 2016, Oncotarget.

A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway

X. Mao, B. Cao, Jingyu Zhu, 2016, Oncotarget.

The Ring Finger Protein RNF6 Induces Leukemia Cell Proliferation as a Direct Target of Pre-B-cell Leukemia Homeobox 1*

X. Mao, B. Cao, Depei Wu, 2016, The Journal of Biological Chemistry.

Dissecting bortezomib: development, application, adverse effects and future direction.

X. Mao, B. Cao, Jie Li, 2013, Current pharmaceutical design.

The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination

M. Moran, X. Mao, B. Cao, 2023, The Journal of biological chemistry.

Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway.

Qi Wang, X. Mao, B. Cao, 2020, Bioscience trends.

Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis

Qi Wang, X. Mao, B. Cao, 2020, Cell communication and signaling : CCS.