L. Walker

S. Auerbach, P. Foster, L. Walker, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Effect of green tea and its polyphenols on mouse liver.

F. Hamada, L. Walker, Z. Ali, 2013, Fitoterapia.

Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity

B. Tekwani, Brice Campo, A. Sampath, 2013, Proceedings of the National Academy of Sciences.

Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema

L. Walker, S. Takamatsu, A. Clark, 2003, Phytotherapy research : PTR.

Cytotoxic and antioxidant activities of alkylated benzoquinones from Maesa lanceolata

L. Walker, S. Takamatsu, H. Fong, 2003, Phytotherapy research : PTR.

Identification of four biliary metabolites of the diterpene sclareol in the laboratory rat.

L. Walker, S. Kouzi, J. Mcchesney, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

Ephedra in perspective – a current review

L. Walker, I. Khan, E. Abourashed, 2003, Phytotherapy research : PTR.

First in class (S,E)-11-[2-(arylmethylene)hydrazono]-PBD analogs as selective CB2 modulators targeting neurodegenerative disorders

L. Walker, M. Otsuka, S. Ross, 2020, Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents.

Mechanisms of 8‐aminoquinoline induced haemolytic toxicity in a G6PDd humanized mouse model

L. Walker, R. Rochford, B. Pybus, 2022, Journal of cellular and molecular medicine.

Constituents of Nelumbo nucifera leaves and their antimalarial and antifungal activity.

H. Elsohly, L. Walker, Shabana I. Khan, 2008, Phytochemistry letters.

A new quassinoid from Castela texana.

L. Walker, R. Sindelar, D. K. Goins, 1996, Journal of natural products.

Pharmacokinetics and Pharmacodynamics of (+)-Primaquine and (−)-Primaquine Enantiomers in Rhesus Macaques (Macaca mulatta)

B. Tekwani, A. Sampath, L. Walker, 2014, Antimicrobial Agents and Chemotherapy.

Emerging therapeutic potential of graviola and its constituents in cancers

S. Batra, A. Qazi, L. Walker, 2018, Carcinogenesis.

Acetylenic acids inhibiting azole-resistant Candida albicans from Pentagonia gigantifolia.

H. Elsohly, Xing-Cong Li, L. Walker, 2003, Journal of natural products.

Effect of antimalarial drug primaquine and its derivatives on the ionization potential of hemoglobin: A QM/MM study.

R. J. Doerksen, L. Walker, Yuanqing Ding, 2013, MedChemComm.

Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes

B. Tekwani, L. Walker, Shabana I. Khan, 2016, Malaria Journal.

δ-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens.

L. Walker, Shabana I. Khan, M. Jacob, 2011, European journal of medicinal chemistry.

Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads

B. Tekwani, L. Walker, S. Jain, 2017, BMC Pharmacology and Toxicology.

Hepatotoxicity of a Cannabidiol-Rich Cannabis Extract in the Mouse Model

Mitchell R. McGill, I. Koturbash, L. Walker, 2019, Molecules.

PXR mediated induction of CYP3A4, CYP1A2, and P‐gp by Mitragyna speciosa and its alkaloids

L. Walker, Shabana I. Khan, V. Manda, 2017, Phytotherapy research : PTR.

Pharmacokinetics and Tolerability of Δ9-THC-Hemisuccinate in a Suppository Formulation as an Alternative to Capsules for the Systemic Delivery of Δ9-THC

L. Walker, M. Elsohly, W. Gul, 2018, Medical Cannabis and Cannabinoids.

Potential Probiotic or Trigger of Gut Inflammation – The Janus-Faced Nature of Cannabidiol-Rich Cannabis Extract

I. Nookaew, I. Koturbash, L. Walker, 2020, Journal of dietary supplements.

Possible hepatocellular toxicity of EGCG under the influence of an inflammagen

F. Hamada, L. Walker, Z. Ali, 2014 .

Identification of an Orally Bioavailable, Brain-Penetrant Compound with Selectivity for the Cannabinoid Type 2 Receptor

L. Walker, J. Rimoldi, S. Ross, 2022, Molecules.

Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box.

K. Gustafson, J. Mcmahon, D. Ferreira, 2018, Chemical Science.

Phenolic compounds from Nymphaea odorata.

H. Elsohly, Xing-Cong Li, L. Walker, 2003, Journal of natural products.

Indolopyridoquinazoline alkaloid from Leptothyrsa sprucei.

H. Elsohly, L. Walker, A. Clark, 2001, Phytochemistry.

Optimization of 3-(phenylthio)quinolinium compounds against opportunistic fungal pathogens.

L. Walker, Shabana I. Khan, M. Jacob, 2011, European journal of medicinal chemistry.

Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes

B. Tekwani, L. Walker, I. Khan, 2019, Malaria Journal.

Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs

B. Tekwani, Brice Campo, L. Walker, 2016, Antimicrobial Agents and Chemotherapy.

Antifungal Activity of Eupolauridine and Its Action on DNA Topoisomerases

L. Walker, Shabana I. Khan, A. Nimrod, 2002, Antimicrobial Agents and Chemotherapy.

Discovery of Antifungal Agents from Natural Sources: Virulence Factor Targets

L. Walker, A. Clark, 1999 .

Tissue factor dependent liver injury causes release of retinoid receptors (RXR-α and RAR-α) as lipid droplets.

L. Walker, M. Abdel-Bakky, M. Hammad, 2011, Biochemical and biophysical research communications.

Paradoxical Patterns of Sinusoidal Obstruction Syndrome-Like Liver Injury in Aged Female CD-1 Mice Triggered by Cannabidiol-Rich Cannabis Extract and Acetaminophen Co-Administration

Mitchell R. McGill, I. Koturbash, L. Walker, 2019, Molecules.

Safety and Molecular-Toxicological Implications of Cannabidiol-Rich Cannabis Extract and Methylsulfonylmethane Co-Administration

Mitchell R. McGill, I. Koturbash, L. Walker, 2020, International journal of molecular sciences.

Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice

L. Walker, M. Abdel-Bakky, M. Hammad, 2013, Journal of applied toxicology : JAT.

Targeting the hemozoin synthesis pathway for new antimalarial drug discovery: technologies for in vitro beta-hematin formation assay.

B. Tekwani, L. Walker, 2005, Combinatorial chemistry & high throughput screening.

DFT study on the radical anions formed by primaquine and its derivatives.

R. J. Doerksen, L. Walker, Haining Liu, 2011, Chemical research in toxicology.

Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens.

L. Walker, Shabana I. Khan, M. Jacob, 2011, Bioorganic & medicinal chemistry.

Rectal Bioavailability of Δ-9-Tetrahydrocannabinol from the Hemisuccinate Ester in Monkeys

Alan B. Jones, L. Walker, M. Elsohly, 1991 .

Structure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agents.

H. Flores-Rozas, L. Walker, Shabana I. Khan, 2013, European journal of medicinal chemistry.

New Labdane Diterpenes from Leonurus cardiaca

H. Elsohly, L. Walker, I. Khan, 2008, Planta medica.

A new dammarane-type triterpene glycoside from Polyscias fulva.

L. Walker, I. Khan, N. Toyang, 2001, Journal of natural products.

Synthesis of A/B-ring partial analogs of bruceantin as potential antimalarial agents.

L. Walker, R. Sindelar, A. Nimrod, 2005, Medicinal chemistry (Shariqah (United Arab Emirates)).

Enantioselective synthesis and complement inhibitory assay of A/B-ring partial analogues of oleanolic acid.

L. Walker, R. Sindelar, A. Nimrod, 2001, Bioorganic & medicinal chemistry letters.

Piperazine-linked bisbenzamidines: a novel class of antileishmanial agents.

B. Tekwani, L. Walker, Tien L. Huang, 2004, European journal of medicinal chemistry.

Antifungal cyclopentenediones from Piper coruscans.

H. Elsohly, D. Ferreira, Xing-Cong Li, 2004, Journal of the American Chemical Society.

Dihydrochalcones from Piper longicaudatum.

H. Elsohly, L. Walker, A. Nimrod, 2001, Planta medica.

Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents.

L. Walker, Shabana I. Khan, M. Jacob, 2007, Bioorganic & medicinal chemistry.

Identification of bis-quindolines as new antiinfective agents.

L. Walker, Shabana I. Khan, M. Jacob, 2005, Bioorganic & medicinal chemistry.

Methemoglobinemia Hemotoxicity of Some Antimalarial 8-Aminoquinoline Analogues and Their Hydroxylated Derivatives: Density Functional Theory Computation of Ionization Potentials.

R. J. Doerksen, B. Tekwani, L. Walker, 2016, Chemical research in toxicology.

Antiparasitic Activities and Toxicities of Individual Enantiomers of the 8-Aminoquinoline 8-[(4-Amino-1-Methylbutyl)Amino]-6-Methoxy-4-Methyl-5-[3,4-Dichlorophenoxy]Quinoline Succinate

V. Yardley, S. Croft, L. Walker, 2008, Antimicrobial Agents and Chemotherapy.

GC-MS Analysis of the 8-Aminoquinoline Antimalarial [NPC1161] and its Carboxy Metabolite in Plasma and Red Blood Cells of Primates

L. Walker, Shabana I. Khan, M. Elsohly, 2006 .

Antioxidant constituents of Nymphaea caerulea flowers.

H. Elsohly, L. Walker, Shabana I. Khan, 2008, Phytochemistry.

Absolute configuration, conformation, and chiral properties of flavanone-(3→8″)-flavone biflavonoids from Rheedia acuminata

H. Elsohly, D. Ferreira, Xing-Cong Li, 2002 .

Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin

G. Ma, L. Walker, Shabana I. Khan, 2004, Lipids.

Constituents of Leonotis leonurus Flowering Tops

H. Elsohly, L. Walker, Shabana I. Khan, 2008 .

Constituents of Leonotis leonurus Flowering Tops

H. Elsohly, L. Walker, Shabana I. Khan, 2008 .

Natural products and antifungal drug discovery.

L. Walker, M. Jacob, 2005, Methods in molecular medicine.

Bioavailability, pharmacokinetics, and tissue distribution of the oxypregnane steroidal glycoside P57AS3 (P57) from Hoodia gordonii in mouse model.

L. Walker, Shabana I. Khan, I. Khan, 2010, Planta medica.

Characterization of in vitro pharmacokinetic properties of hoodigogenin A from Hoodia gordonii.

L. Walker, Shabana I. Khan, I. Khan, 2010, Planta medica.

In vitro metabolic stability and intestinal transport of P57AS3 (P57) from Hoodia gordonii and its interaction with drug metabolizing enzymes.

L. Walker, Shabana I. Khan, I. Khan, 2008, Planta medica.

Clinically Relevant Pharmacokinetic Herb-drug Interactions in Antiretroviral Therapy.

L. Walker, P. Fasinu, B. Gurley, 2015, Current drug metabolism.

Two polymethoxylated flavonoids with antioxidant activities and a rearranged clerodane diterpenoid from the leaf exudates of Microglossa pyrifolia

B. Tekwani, L. Walker, J. Midiwo, 2015 .

Flavanone glycosides from Miconia trailii.

H. Elsohly, Xing-Cong Li, L. Walker, 2003, Journal of natural products.

Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline

L. Walker, Shabana I. Khan, V. Manda, 2014, Planta Medica.

Biologically active steroidal glycosides from Tribulus terrestris.

L. Walker, I. Khan, E. Bedir, 2002, Die Pharmazie.

Induction of GST and related events by dietary phytochemicals: sources, chemistry, and possible contribution to chemoprevention.

L. Walker, I. Khan, A. Galal, 2015, Current topics in medicinal chemistry.

Absolute Configuration, Conformation, and Chiral Properties of Flavanone‐(3→8′′)‐Flavone Biflavonoids from Rheedia acuminata.

H. Elsohly, D. Ferreira, Xing-Cong Li, 2003 .

Phytochemical, Antimicrobial and Antiplasmodial Investigations of Terminalia brownii

B. Tekwani, L. Walker, Shabana I. Khan, 2013, Natural product communications.

New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert

L. Walker, Shabana I. Khan, M. Langat, 2016, Planta Medica.

Biologically active quassinoids and their chemistry: potential leads for drug design.

L. Walker, R. Sindelar, S. Vangapandu, 2005, Current medicinal chemistry.

Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.

Ikhlas A Khan, Xing-Cong Li, Daneel Ferreira, 2002, Journal of natural products.

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

Nathaniel R. Twarog, B. Tekwani, A. Shelat, 2016, Malaria Journal.

Screening North American plant extracts in vitro against Trypanosoma brucei for discovery of new antitrypanosomal drug leads

B. Tekwani, L. Walker, S. Jain, 2016, BMC Complementary and Alternative Medicine.

Cytochrome P450‐dependent toxicity of dapsone in human erythrocytes

B. Tekwani, L. Walker, Shobana Ganesan, 2009, Journal of applied toxicology : JAT.

The Marine Sponge-Derived Polyketide Endoperoxide Plakortide F Acid Mediates Its Antifungal Activity by Interfering with Calcium Homeostasis

Bharathi Avula, Tao Xu, Melissa R. Jacob, 2011, Antimicrobial Agents and Chemotherapy.

Modulation of CYPs, P-gp, and PXR by Eschscholzia californica (California Poppy) and Its Alkaloids

S. Cutler, L. Walker, Shabana I. Khan, 2016, Planta Medica.

Meroterpenoids with Antiproliferative Activity from a Hawaiian-Plant Associated Fungus Peyronellaea coffeae-arabicae FT238.

J. Turkson, P. Fei, L. Walker, 2016, Organic letters.

New indole alkaloids from the bark of Nauclea orientalis.

H. Elsohly, L. Walker, M. Jacob, 2001, Journal of natural products.

Circular dichroic properties of flavan-3,4-diols.

D. Ferreira, L. Walker, D. Slade, 2004, Journal of natural products.

Pharmacological activities of some Argyranthemum species growing in the Canary Islands

L. Walker, J. Francisco‐Ortega, M. Couladis, 2004, Phytotherapy research : PTR.

Tirucallane-type triterpenoids: nmr and X-ray diffraction analyses of 24-epi-piscidinol A and piscidinol A

L. Walker, R. Sindelar, R. Rogers, 1997 .

Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices.

L. Walker, Z. Ali, I. Khan, 2017, ACS chemical biology.

Development and Evaluation of a Novel Dissolution Apparatus for Medicated Chewing Gum Products

Alan B. Jones, W. Chambliss, L. Walker, 1992, Pharmaceutical Research.

Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial Herbs—Implication for Herb-Drug Interaction

L. Walker, Shabana I. Khan, V. Manda, 2017, Molecules.

Diversity and Biological Activities of Endophytic Fungi Associated with Micropropagated Medicinal Plant Echinacea purpurea (L.) Moench

Natasha M. Agramonte, L. Walker, U. Bernier, 2012 .

Role of Heme in the Antifungal Activity of the Azaoxoaporphine Alkaloid Sampangine

Tao Xu, Melissa R. Jacob, Alice M. Clark, 2007, Eukaryotic Cell.

Spectrophotometric determination of de novo hemozoin/beta-hematin formation in an in vitro assay.

B. Tekwani, L. Walker, Shabana I. Khan, 2004, Analytical biochemistry.

Genome-wide Expression Profiling of the Response to Polyene, Pyrimidine, Azole, and Echinocandin Antifungal Agents in Saccharomyces cerevisiae*

J. Cleary, L. Walker, K. Barker, 2003, Journal of Biological Chemistry.

Aromatic constituents of Uvaria grandiflora.

B. Tekwani, H. Elsohly, Xing-Cong Li, 2006, Journal of natural products.

Phenolic glycosides from Potalia amara.

H. Elsohly, Xing-Cong Li, L. Walker, 2005, Planta medica.

An alpha-proteobacterial type malate dehydrogenase may complement LDH function in Plasmodium falciparum. Cloning and biochemical characterization of the enzyme.

B. Tekwani, L. Walker, Shabana I. Khan, 2004, European journal of biochemistry.

Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.

J. Baird, H. Myint, Jonathan Berman, 2011, The American journal of tropical medicine and hygiene.

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Richard J Sciotti, L. Walker, Robert E. Christian, 2012, Malaria Journal.

In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji)

L. Walker, Shabana I. Khan, I. Khan, 2019, Heliyon.

Antifungal chalcones from Maclura tinctoria.

H. Elsohly, L. Walker, A. Nimrod, 2001, Planta medica.

The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro.

B. Katzenellenbogen, L. Walker, Shabana I. Khan, 2016, Archives of biochemistry and biophysics.

FURTHER STRUCTURE-ACTIVITY-RELATIONSHIP STUDIES ON A/C/D-RING ANALOGS OF COMPLEMENT INHIBITOR K-76

L. Walker, R. Sindelar, R. Srivastava, 1995 .

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities.

L. Walker, Shabana I. Khan, V. Manda, 2015, Drug metabolism letters.

Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome.

L. Walker, Shabana I. Khan, I. Khan, 2012, Chemical research in toxicology.

Content versus Label Claims in Cannabidiol (CBD)-Containing Products Obtained from Commercial Outlets in the State of Mississippi

L. Walker, T. Murphy, B. Gurley, 2020, Journal of dietary supplements.

Potential utility of natural products as regulators of breast cancer-associated aromatase promoters

L. Walker, Shabana I. Khan, Jianping Zhao, 2011, Reproductive biology and endocrinology : RB&E.

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry

B. Tekwani, L. Walker, Shabana I. Khan, 2018, Malaria Journal.

Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice

B. Tekwani, L. Walker, P. Fasinu, 2022, Malaria Journal.

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

D. Caridha, L. Walker, C. Ockenhouse, 2013, Malaria Journal.

Pentacyclic Ingamine Alkaloids, a New Antiplasmodial Pharmacophore from the Marine Sponge Petrosid Ng5 Sp5

B. Tekwani, L. Walker, Shabana I. Khan, 2012, Planta Medica.

Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.

B. Tekwani, L. Walker, N. D. Chaurasiya, 2012, Toxicology.

Analysis of quaternary structure of a [LDH-like] malate dehydrogenase of Plasmodium falciparum with oligomeric mutants

B. Tekwani, L. Walker, Prasenjit Mukherjee, 2009, Molecular and Cellular Biochemistry.

Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine

L. Walker, Shabana I. Khan, V. Manda, 2015, Medicines.

Inhibitors of ubiquitin E3 ligase as potential new antimalarial drug leads

B. Tekwani, L. Walker, S. Jain, 2017, BMC Pharmacology and Toxicology.

Characterization of Mycotypha metabolites found to be inhibitors of cell adhesion molecules.

H. Elsohly, L. Walker, K. Schrader, 2002, The Journal of antibiotics.

Genipatriol, a new cycloartane triterpene from Genipa spruceana.

L. Walker, C. F. Hossain, D. Nagle, 2003, Journal of natural products.

Evaluation of inhibitors of histone deacetylases as potential neurotrophic agents

B. Tekwani, L. Walker, I. Muhammad, 2014 .

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

B. Katzenellenbogen, L. Walker, Shabana I. Khan, 2013, In Vitro Cellular & Developmental Biology - Animal.

A New Metabolite with a Unique 4-Pyranone-γ-Lactam-1,4-Thiazine Moiety from a Hawaiian-Plant Associated Fungus.

J. Turkson, L. Walker, Chunshun Li, 2015, Organic letters.

Quantitative analysis of primaquine and its metabolites in human urine using liquid chromatography coupled with tandem mass spectrometry.

B. Tekwani, L. Walker, I. Khan, 2022, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Enantioselective metabolism of primaquine by human CYP2D6

B. Tekwani, L. Walker, Shabana I. Khan, 2014, Malaria Journal.

Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha.

L. Walker, S. Takamatsu, A. Clark, 2001, Journal of natural products.

Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B †

R. J. Doerksen, B. Tekwani, L. Walker, 2021, Pharmaceuticals.

Enantioselective Pharmacokinetics of Primaquine in Healthy Human Volunteers

B. Tekwani, I. Khan, L. Walker, 2015, Drug Metabolism and Disposition.

Enantioselective metabolism of primaquine by human CYP2D6

B. Tekwani, L. Walker, Shabana I. Khan, 2014, Malaria Journal.

Indolizidine, antiinfective and antiparasitic compounds from Prosopis glandulosa var. glandulosa.

B. Tekwani, L. Walker, Shabana I. Khan, 2009, Journal of natural products.

Reversal of fluconazole resistance in multidrug efflux-resistant fungi by the Dysidea arenaria sponge sterol 9alpha,11alpha-epoxycholest-7-ene-3beta,5alpha,6alpha,19-tetrol 6-acetate.

L. Walker, C. F. Hossain, D. Nagle, 2003, Journal of natural products.

Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

B. Tekwani, L. Walker, I. Khan, 2016, Malaria Journal.

First in class (S,E)-11-[2-(arylmethylene)hydrazono]-PBD analogs as selective CB2 modulators targeting neurodegenerative disorders

L. Walker, M. Otsuka, S. Ross, 2020, Medicinal Chemistry Research.

Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells

T. Efferth, L. Walker, Shabana I. Khan, 2016, Front. Pharmacol..

Phenolic compounds from Miconia myriantha inhibiting Candida aspartic proteases.

H. Elsohly, L. Walker, A. Nimrod, 2001, Journal of natural products.

Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents

L. Walker, P. Fasinu, M. Elsohly, 2016, Pharmacotherapy.

A new antimalarial quassinoid from Simaba orinocensis.

J. Pelletier, B. Tekwani, L. Walker, 2004, Journal of natural products.

Pharmacokinetics and Pharmacodynamics of ( (cid:2) )-Primaquine and ( (cid:3) )-Primaquine Enantiomers in Rhesus Macaques ( Macaca mulatta )

B. Tekwani, A. Sampath, L. Walker, 2014 .

Primaquine Enantiomers : Scalable Preparation and Differential 1 Pharmacologic and Toxicologic Profiles

Wickham, B. Tekwani, L. Walker, 2014 .

Analysis of primaquine and its metabolite carboxyprimaquine in biological samples: enantiomeric separation, method validation and quantification.

B. Tekwani, L. Walker, Shabana I. Khan, 2011, Biomedical chromatography : BMC.

Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling.

B. Tekwani, L. Walker, Shabana I. Khan, 2013, Journal of mass spectrometry : JMS.

Antiparasitic alkaloids from Psychotria klugii.

Satoshi Takamatsu, Erdal Bedir, Daneel Ferreira, 2003, Journal of natural products.

Therapeutic Intervention of COVID-19 by Natural Products: A Population-Specific Survey Directed Approach

L. Walker, M. Hasan, I. Espinoza, 2021, Molecules.

Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay.

L. Walker, Shabana I. Khan, Z. Ali, 2009, Planta medica.

Excretion of Metabolites in Bile Following the Administration of Primaquine to Rats

L. Walker, J. K. Baker, J. McChesney, 1985, Pharmaceutical Research.

Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers

B. Tekwani, L. Walker, F. Fronczek, 2014, Antimicrobial Agents and Chemotherapy.

Isolation of Acacetin from Calea urticifolia with Inhibitory Properties against Human Monoamine Oxidase-A and -B.

Khaled M. Elokely, M. Klein, B. Tekwani, 2016, Journal of natural products.

Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate

G. Ma, L. Walker, Shabana I. Khan, 2005, Lipids.

Natural products inhibiting Candida albicans secreted aspartic proteases from Lycopodium cernuum.

H. Elsohly, L. Walker, Zhizhen Zhang, 2002, Journal of natural products.

New sesquiterpenoids from the root of Guatteria multivenia.

H. Elsohly, L. Walker, Zhizhen Zhang, 2002, Journal of natural products.

Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice

L. Walker, M. Abdel-Bakky, M. Hammad, 2011, Archives of Toxicology.

Dietary supplements: safety issues and quality control.

L. Walker, B. Gurley, Deborah S. Minor, 2011, Archives of internal medicine.

An LC–MS based study of the metabolic profile of primaquine, an 8-aminoquinoline antiparasitic drug, with an in vitro primary human hepatocyte culture model

L. Walker, X. Jin, B. Pybus, 2014, European Journal of Drug Metabolism and Pharmacokinetics.

New Chloroquine Analogues as Antiviral Agents

L. Walker, L. Dias, D. Nanayakkara, 2006 .

Biologically active secondary metabolites from Ginkgo biloba.

L. Walker, P. Goldman, Jianping Zhao, 2002, Journal of agricultural and food chemistry.

Juniper Berries Regulate Diabetes and Obesity Markers Through Modulating PPARα, PPARγ, and LXR: In Vitro and In Vivo Effects.

L. Walker, Shabana I. Khan, I. Khan, 2023, Journal of medicinal food.

Differential Cytochrome P450 2D Metabolism Alters Tafenoquine Pharmacokinetics

B. Tekwani, R. Paris, L. Walker, 2015, Antimicrobial Agents and Chemotherapy.

How physicians should evaluate dietary supplements.

L. Walker, J. Glisson, 2010, The American journal of medicine.

A new triterpene from Leandra chaetodon.

H. Elsohly, Xing-Cong Li, L. Walker, 2003, Planta medica.

Automated high-throughput system to fractionate plant natural products for drug discovery.

Kip Guy, Anang A Shelat, A. Shelat, 2010, Journal of natural products.

Transport of Schisandra chinensis extract and its biologically‐active constituents across Caco‐2 cell monolayers — an in‐vitro model of intestinal transport

L. Walker, Shabana I. Khan, I. Khan, 2008, The Journal of pharmacy and pharmacology.

Transport of harman alkaloids across Caco-2 cell monolayers.

L. Walker, Shabana I. Khan, I. Khan, 2004, Chemical & pharmaceutical bulletin.

Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents

L. Walker, Shabana I. Khan, V. Manda, 2014, Front. Pharmacol..

Mechanism for neurotropic action of vorinostat, a pan histone deacetylase inhibitor

B. Tekwani, L. Walker, Z. Shariat-Madar, 2016, Molecular and Cellular Neuroscience.

Growth, Drug Susceptibility, and Gene Expression Profiling of Plasmodium falciparum Cultured in Medium Supplemented with Human Serum

B. Tekwani, L. Walker, Shabana I. Khan, 2007, Journal of biomolecular screening.

In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in combination with chloroquine

B. Tekwani, L. Walker, Rajnish Sahu, 2014, Malaria Journal.

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

Nathaniel R. Twarog, B. Tekwani, A. Shelat, 2016, Malaria Journal.

Drug Discovery from Complex Mixtures: Serendipity, Screening, and Characterization

Melissa R. Jacob, Xing-Cong Li, Larry A. Walker, 2019, The Science and Regulations of Naturally Derived Complex Drugs.

NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation

B. Tekwani, R. Dinglasan, L. Walker, 2019, Front. Pharmacol..

Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration

B. Tekwani, L. Walker, M. Elsohly, 2023, Frontiers in Pharmacology.

Synthesis of [13C6]primaquine.

L. Walker, N. Nanayakkara, H. Herath, 2013, Journal of labelled compounds & radiopharmaceuticals.

LC-MS- and (1)H NMR Spectroscopy-Guided Identification of Antifungal Diterpenoids from Sagittaria latifolia.

Xing-Cong Li, L. Walker, Shabana I. Khan, 2015, Journal of natural products.

Hydroxylated Derivatives of NPC1161: Theoretical Insights into Their Potential Toxicity and the Feasibility and Regioselectivity of Their Formation

R. J. Doerksen, B. Tekwani, L. Walker, 2014, The journal of physical chemistry. A.

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

B. Tekwani, L. Walker, N. Nanayakkara, 2012, Bioorganic & medicinal chemistry letters.

L-tryptophan Induced Eosinophilia-Myalgia Syndrome

L. Walker, C E Lindgren, L A Walker, 1991, Journal of the Royal Society of Health.

Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B

B. Tekwani, S. Cutler, L. Walker, 2017, Evidence-based complementary and alternative medicine : eCAM.

A new naphthopyrone derivative from Cassia quinquangulata and structural revision of quinquangulin and its glycosides.

H. Elsohly, L. Walker, A. Nimrod, 2001, Journal of Natural Products.

A New Quassinoid from Crude Quassin-extract of Quassia amara

L. Walker, R. Sindelar, D. K. Goins, 1996 .

Δ9-THC Hemisuccinate in Suppository Form as an Alternative to Oral and Smoked THC

L. Walker, M. Elsohly, A. Best, 1999 .

Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway

L. Walker, Shabana I. Khan, V. Manda, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

CYTOTOXIC AND ANTIOXIDANT ACTIVITY OF M. LANCEOLATA

L. Walker, S. Takamatsu, H. Fong, 2003 .

Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase.

R. J. Doerksen, L. Walker, N. Nanayakkara, 2011, Journal of the American Chemical Society.

Rectal bioavailability of delta-9-tetrahydrocannabinol from various esters

L. Walker, M. Elsohly, A. Hikal, 1991, Pharmacology Biochemistry and Behavior.

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

Juliana M. Sá, Marvin L. Thomas, J. Bailey, 2019, Nature Communications.

Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs

B. Tekwani, L. Walker, R. Rochford, 2016, Antimicrobial Agents and Chemotherapy.

Cannabis cultivation: Methodological issues for obtaining medical-grade product

David J Potter, L. Walker, M. Elsohly, 2017, Epilepsy & Behavior.

The Marine Sponge-Derived Polyketide Endoperoxide Plakortide F Acid Mediates Its Antifungal Activity by Interfering with Calcium Homeostasis

I. Khan, L. Walker, M. Hamann, 2011, Antimicrobial Agents and Chemotherapy.

Transport of Schisandra chinensis extract and its biologically‐active constituents across Caco‐2 cell monolayers — an in‐vitro model of intestinal transport

L. Walker, Shabana I. Khan, I. Khan, 2008, The Journal of pharmacy and pharmacology.

Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents

L. Walker, Shabana I. Khan, V. Manda, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

New acylphloroglucinol derivatives with diverse architectures from Hypericum henryi.

D. Ferreira, L. Walker, Gang Xu, 2014, Organic letters.

Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells

B. Katzenellenbogen, L. Walker, Shabana I. Khan, 2014, In Vitro Cellular & Developmental Biology - Animal.

In Vitro and In Vivo Interactions of Furosemide and Sucralfate

L. Walker, A. Hikal, Thirucote Ramachandran, 1987, Pharmaceutical Research.

Structure and function of Plasmodium falciparum malate dehydrogenase: role of critical amino acids in co-substrate binding pocket.

B. Tekwani, L. Walker, Prasenjit Mukherjee, 2009, Biochimie.

Structure and function of Plasmodium falciparum malate dehydrogenase : Role of critical amino acids in co-substrate binding pocket q

B. Tekwani, L. Walker, Prasenjit Mukherjee, 2022 .