Guanghong Jia

发表

Regulation of cell cycle entry by PTEN in smooth muscle cell proliferation of human coronary artery bypass conduits

D. Agrawal, A. Mitra, Guanghong Jia, 2008, Journal of cellular and molecular medicine.

Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity

J. Sowers, Guanghong Jia, M. Hill, 2018, Circulation research.

Neuropeptide Y receptors in carotid plaques of symptomatic and asymptomatic patients: effect of inflammatory cytokines.

I. Pipinos, D. Agrawal, Guanghong Jia, 2011, Experimental and molecular pathology.

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance.

V. Demarco, J. Sowers, Guanghong Jia, 2013, Metabolism: clinical and experimental.

Overview of Autophagy and Cardiometabolic Syndrome

J. Sowers, Guanghong Jia, A. Aroor, 2018 .

Glycemic control by the SGLT2 inhibitor empagliflozin decreases aortic stiffness, renal resistivity index and kidney injury

V. Demarco, B. Chandrasekar, Guanghong Jia, 2018, Cardiovascular Diabetology.

Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice

V. Demarco, J. Sowers, C. Manrique, 2016, Cardiovascular Diabetology.

Tumor necrosis factor-α regulates p27 kip expression and apoptosis in smooth muscle cells of human carotid plaques via forkhead transcription factor O1.

D. Agrawal, Guanghong Jia, S. Tyndall, 2011, Experimental and molecular pathology.

Insulin‐like growth factor‐1 and TNF‐α regulate autophagy through c‐jun N‐terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells

D. Agrawal, Guanghong Jia, D. M. Gangahar, 2006, Immunology and cell biology.

Overnutrition, mTOR signaling, and cardiovascular diseases.

J. Sowers, Guanghong Jia, L. Martinez‐Lemus, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.

V. Demarco, J. Sowers, C. Manrique, 2017, Metabolism: clinical and experimental.

Vascular stiffness in insulin resistance and obesity

V. Demarco, J. Sowers, Guanghong Jia, 2015, Front. Physiol..

The VASP Road to NAFLD: A Macrophage Detour

J. Sowers, G. Lastra, C. Manrique, 2015, Diabetes.

Differential effects of insulin‐like growth factor‐1 and atheroma‐associated cytokines on cell proliferation and apoptosis in plaque smooth muscle cells of symptomatic and asymptomatic patients with carotid stenosis

D. Agrawal, Guanghong Jia, G. Cheng, 2006, Immunology and cell biology.

Cross-talk between angiotensin II and IGF-1-induced connexin 43 expression in human saphenous vein smooth muscle cells

D. Agrawal, Guanghong Jia, D. M. Gangahar, 2011, Journal of cellular and molecular medicine.

Angiotensin II and IGF-1 regulate connexin43 expression via ERK and p38 signaling pathways in vascular smooth muscle cells of coronary artery bypass conduits.

D. Agrawal, A. Mitra, Guanghong Jia, 2007, The Journal of surgical research.

Potential Role of Antihypertensive Medications in Preventing Excessive Arterial Stiffening

J. Sowers, Guanghong Jia, L. Martinez‐Lemus, 2018, Current Hypertension Reports.

Insulin resistance, cardiovascular stiffening and cardiovascular disease.

J. Sowers, Guanghong Jia, Zhe Sun, 2021, Metabolism: clinical and experimental.

Endothelial cell senescence in aging-related vascular dysfunction.

J. Sowers, Guanghong Jia, A. Aroor, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Epithelial sodium channels in endothelial cells mediate diet-induced endothelium stiffness and impaired vascular relaxation in obese female mice.

F. Jaisser, J. Sowers, G. Lastra, 2019, Metabolism: clinical and experimental.

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in Females.

V. Demarco, J. Sowers, Guanghong Jia, 2016, Circulation research.

Arterial Stiffness: A Nexus between Cardiac and Renal Disease

J. Sowers, Guanghong Jia, A. Aroor, 2014, Cardiorenal Medicine.

Endothelial dysfunction potentially interacts with impaired glucose metabolism to increase cardiovascular risk.

J. Sowers, Guanghong Jia, 2014, Hypertension.

Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease

J. Sowers, Guanghong Jia, A. Whaley-connell, 2017, Diabetologia.

Glucagon-Like Peptide 1 Receptor Activation and Platelet Function: Beyond Glycemic Control

J. Sowers, Guanghong Jia, A. Aroor, 2016, Diabetes.

Diabetic Cardiomyopathy

J. Sowers, Guanghong Jia, M. Hill, 2018 .

Diet-Induced Obesity Promotes Kidney Endothelial Stiffening and Fibrosis Dependent on the Endothelial Mineralocorticoid Receptor

J. Sowers, Guanghong Jia, A. Whaley-connell, 2019, Hypertension.

Integrated In Silico-In Vitro Identification and Optimization of Bone Morphogenic Protein-2 Armpit Epitope as Its Antagonist Binding Site

Guanghong Jia, Yanping Wu, Haiyan Chi, 2020, The Protein Journal.

Increased Fibro-Adipogenic Progenitors and Intramyocellular Lipid Accumulation in Obesity-Related Skeletal Muscle Dysfunction

J. Sowers, Guanghong Jia, 2018, Diabetes.

Xanthine oxidase inhibition protects against Western diet-induced aortic stiffness and impaired vasorelaxation in female mice.

J. Sowers, G. Lastra, C. Manrique, 2017, American journal of physiology. Regulatory, integrative and comparative physiology.

Differential Mode of Action GLP-1-Based Strategies: A Physiological Analysis of

V. Demarco, J. Sowers, Guanghong Jia, 2015 .

Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes

V. Demarco, J. Sowers, Guanghong Jia, 2017, Cardiovascular Diabetology.

Role of Metabolic Factors: Lipids, Glucose/Insulin Intolerance

J. Sowers, Guanghong Jia, A. Aroor, 2015 .

Fructose and Uric Acid: Is There a Role in Endothelial Function?

J. Sowers, Guanghong Jia, A. Whaley-connell, 2014, Current Hypertension Reports.

Estrogen and mitochondria function in cardiorenal metabolic syndrome.

J. Sowers, Guanghong Jia, A. Aroor, 2014, Progress in molecular biology and translational science.

Glucose, Insulin and Potential Strategies of Vascular Stiffening

J. Sowers, Guanghong Jia, G. Meininger, 2014 .

High glucose enhances angiotensin-II-mediated peroxisome proliferation-activated receptor-gamma inactivation in human coronary artery endothelial cells.

Jiliang Wu, Guanghong Jia, J. Xiang, 2010, Experimental and molecular pathology.

Involvement of connexin 43 in angiotensin II-induced migration and proliferation of saphenous vein smooth muscle cells via the MAPK-AP-1 signaling pathway.

D. Agrawal, Guanghong Jia, D. M. Gangahar, 2008, Journal of molecular and cellular cardiology.

Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein.

D. Agrawal, A. Mitra, Guanghong Jia, 2010, Experimental and molecular pathology.

The role of mineralocorticoid receptor signaling in the cross-talk between adipose tissue and the vascular wall

J. Sowers, Guanghong Jia, A. Aroor, 2017, Cardiovascular research.

Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness

V. Demarco, B. Chandrasekar, S. Mummidi, 2021, Cardiovascular Diabetology.

Mineralocorticoid Receptor Activation in Vascular Insulin Resistance and Dysfunction

J. Sowers, Guanghong Jia, M.A. Hill, 2022, International journal of molecular sciences.

Role of Perivascular Adipose Tissue on Vascular Reactive Oxygen Species in Type 2 Diabetes: A Give-and-Take Relationship

J. Sowers, Guanghong Jia, V. Vieira-Potter, 2015, Diabetes.

Inhibition of sphingomyelinase attenuates diet - Induced increases in aortic stiffness.

V. Demarco, J. Sowers, Guanghong Jia, 2022, Journal of molecular and cellular cardiology.

Mineralocorticoid receptors in the pathogenesis of insulin resistance and related disorders: From basic studies to clinical disease.

J. Sowers, Guanghong Jia, W. Lockette, 2021, American journal of physiology. Regulatory, integrative and comparative physiology.

Enhanced endothelium epithelial sodium channel signaling prompts left ventricular diastolic dysfunction in obese female mice.

V. Demarco, J. Sowers, Guanghong Jia, 2018, Metabolism: clinical and experimental.

Targeting endothelial exosomes for the prevention of cardiovascular disease.

J. Sowers, Guanghong Jia, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Running title: Overnutrition and mTOR in cardiovascular diseases

Sowers, J. Sowers, Guanghong Jia, 2014 .

Autophagy: a housekeeper in cardiorenal metabolic health and disease.

J. Sowers, Guanghong Jia, 2015, Biochimica et biophysica acta.

Amiloride Improves Endothelial Function and Reduces Vascular Stiffness in Female Mice Fed a Western Diet

V. Demarco, J. Sowers, Guanghong Jia, 2017, Front. Physiol..

Role of matrix Gla protein in angiotensin II-induced exacerbation of vascular calcification.

D. Agrawal, Guanghong Jia, D. M. Gangahar, 2012, American journal of physiology. Heart and circulatory physiology.

Autophagy of Vascular Smooth Muscle Cells in Atherosclerotic Lesions

D. Agrawal, Guanghong Jia, G. Cheng, 2007, Autophagy.

Interaction of Islet α-Cell and β-Cell in the Regulation of Glucose Homeostasis in HI/HA Syndrome Patients With the GDHH454Y Mutation

J. Sowers, Guanghong Jia, 2014, Diabetes.

Contents Vol. 9, 2019

Connie M. Rhee, D. Lackland, B. Falkner, 2019, CardioRenal Medicine.

Endothelial cell-specific mineralocorticoid receptor activation promotes diastolic dysfunction in diet induced obese male mice.

J. Sowers, G. Lastra, Guanghong Jia, 2022, American journal of physiology. Regulatory, integrative and comparative physiology.

Cystamine reduces vascular stiffness in Western diet-fed female mice.

Thaysa Ghiarone, G. Lastra, Guanghong Jia, 2021, American journal of physiology. Heart and circulatory physiology.

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

J. Sowers, Guanghong Jia, V. DeMarco, 2016, Nature Reviews Endocrinology.

Targeting CITED2 for Angiogenesis in Obesity and Insulin Resistance

J. Sowers, Guanghong Jia, 2016, Diabetes.

Western diet induces renal artery endothelial stiffening that is dependent on the epithelial sodium channel.

F. Jaisser, J. Sowers, G. Lastra, 2020, American journal of physiology. Renal physiology.

Epithelial Sodium Channel in Aldosterone-Induced Endothelium Stiffness and Aortic Dysfunction

F. Jaisser, J. Sowers, Guanghong Jia, 2018, Hypertension.

Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice.

J. Sowers, C. Manrique, Guanghong Jia, 2015, American journal of physiology. Heart and circulatory physiology.

Mineralocorticoid Receptors: An Appealing Target to Treat Coronary Microvascular Dysfunction in Diabetes

J. Sowers, Guanghong Jia, S. Bender, 2014, Diabetes.

Role of Renin-Angiotensin-Aldosterone System Activation in Promoting Cardiovascular Fibrosis and Stiffness

J. Sowers, Guanghong Jia, M. Hill, 2018, Hypertension.

Hypertension in Diabetes: An Update of Basic Mechanisms and Clinical Disease

J. Sowers, Guanghong Jia, 2021, Hypertension.

Uric Acid Promotes Left Ventricular Diastolic Dysfunction in Mice Fed a Western Diet

J. Sowers, Guanghong Jia, A. Whaley-connell, 2015, Hypertension.

Temporal PTEN inactivation causes proliferation of saphenous vein smooth muscle cells of human CABG conduits

D. Agrawal, A. Mitra, Guanghong Jia, 2008, Journal of cellular and molecular medicine.

Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

J. Sowers, Guanghong Jia, A. Whaley-connell, 2015, Hypertension.

Cellular mechanisms underlying obesity-induced arterial stiffness.

J. Sowers, Guanghong Jia, A. Aroor, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

Regular Exercise Reduces Endothelial Cortical Stiffness in Western Diet–Fed Female Mice

F. Booth, J. Sowers, C. Manrique, 2016, Hypertension.

Arterial Stiffening in Western Diet-Fed Mice Is Associated with Increased Vascular Elastin, Transforming Growth Factor-β, and Plasma Neuraminidase

C. Reyes-Aldasoro, J. Sowers, Guanghong Jia, 2016, Front. Physiol..

Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system.

J. Sowers, Guanghong Jia, A. Aroor, 2014, American journal of physiology. Heart and circulatory physiology.

Endothelium-Derived Hyperpolarizing Factors: A Potential Therapeutic Target for Vascular Dysfunction in Obesity and Insulin Resistance

J. Sowers, W. Durante, Guanghong Jia, 2016, Diabetes.

Contribution of Maladaptive Adipose Tissue Expansion to Development of Cardiovascular Disease.

J. Sowers, Guanghong Jia, Yan Jia, 2016, Comprehensive Physiology.

Insulin-like growth factor-I receptors in atherosclerotic plaques of symptomatic and asymptomatic patients with carotid stenosis: effect of IL-12 and IFN-γ

D. Agrawal, Guanghong Jia, G. Cheng, 2007 .

Mitochondrial functional impairment in response to environmental toxins in the cardiorenal metabolic syndrome

J. Sowers, Guanghong Jia, L. Martinez‐Lemus, 2015, Archives of Toxicology.

Role of mineralocorticoid receptor activation in cardiac diastolic dysfunction.

J. Sowers, Guanghong Jia, Yan Jia, 2017, Biochimica et biophysica acta. Molecular basis of disease.

The Role of Tissue Renin-Angiotensin-Aldosterone System in the Development of Endothelial Dysfunction and Arterial Stiffness

J. Sowers, Guanghong Jia, Zhe Sun, 2013, Front. Endocrinol..

Role of intestinal Na(+)/H(+) exchanger inhibition in the prevention of cardiovascular and kidney disease.

Guanghong Jia, Yan Jia, 2015, Annals of translational medicine.

Low-Dose Mineralocorticoid Receptor Blockade Prevents Western Diet–Induced Arterial Stiffening in Female Mice

J. Sowers, C. Manrique, Guanghong Jia, 2015, Hypertension.

Endothelial Estrogen Receptor-α Does Not Protect Against Vascular Stiffness Induced by Western Diet in Female Mice.

J. Sowers, G. Lastra, C. Manrique, 2016, Endocrinology.

Caveolin-1 in Cardiovascular Disease: A Double-Edged Sword

J. Sowers, Guanghong Jia, 2015, Diabetes.

Mitochondrial functional impairment in response to environmental toxins in the cardiorenal metabolic syndrome

J. Sowers, Guanghong Jia, L. Martinez‐Lemus, 2015, Archives of Toxicology.

Autoantibodies of β-adrenergic and M2 cholinergic receptors: atrial fibrillation in hyperthyroidism

J. Sowers, Guanghong Jia, 2015, Endocrine.

Involvement of chloride channels in IGF-I-induced proliferation of porcine arterial smooth muscle cells.

D. Agrawal, Guanghong Jia, G. Cheng, 2007, Cardiovascular research.

Insulin-like growth factor-I receptors in atherosclerotic plaques of symptomatic and asymptomatic patients with carotid stenosis: effect of IL-12 and IFN-gamma.

D. Agrawal, Guanghong Jia, G. Cheng, 2007, American journal of physiology. Heart and circulatory physiology.

Abstract 136: Mineralocorticoid Receptor Activation In Macrophages Mediates High Fat/high Sucrose Induced Vascular Stiffness in Female Mice

J. Sowers, G. Lastra, C. Manrique, 2015, HYPERTENSION.

Mineralocorticoid receptors mediates diet - induced lipid infiltration of skeletal muscle and insulin resistance.

J. Sowers, Guanghong Jia, J. Habibi, 2022, Endocrinology.

Endothelial sodium channel activation mediates DOCA-salt-induced endothelial cell and arterial stiffening.

F. Jaisser, J. Sowers, Guanghong Jia, 2022, Metabolism: clinical and experimental.

Insulin-like growth factor-1 induces phosphorylation of PI3K-Akt/PKB to potentiate proliferation of smooth muscle cells in human saphenous vein.

D. Agrawal, A. Mitra, Guanghong Jia, 2010, Experimental and molecular pathology.

Endothelial sodium channel activation promotes cardiac stiffness and diastolic dysfunction in western diet fed female mice.

J. Sowers, W. Durante, G. Lastra, 2020, Metabolism: clinical and experimental.

Vascular endothelial mineralocorticoid receptors and epithelial sodium channels in metabolic syndrome and related cardiovascular disease

J. Sowers, Guanghong Jia, M.A. Hill, 2023, Journal of molecular endocrinology.

Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

J. Sowers, Guanghong Jia, G. Meininger, 2015, Hypertension.

Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.

J. Sowers, C. Manrique, Guanghong Jia, 2017, Metabolism: clinical and experimental.

Role of matrix Gla protein in angiotensin II-induced exacerbation of vascular calcification.

D. Agrawal, Guanghong Jia, D. M. Gangahar, 2012, American journal of physiology. Heart and circulatory physiology.

Endothelial Cell Serum and Glucocorticoid Regulated Kinase 1 (SGK1) Mediates Vascular Stiffening

Guanghong Jia, A. Aroor, Liping Zhang, 2023, bioRxiv.

Diabetic Vasculopathy: Molecular Mechanisms and Clinical Insights

Guanghong Jia, George Jia, James R. Sowers, 2024, International journal of molecular sciences.

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in Females.

J. Sowers, Guanghong Jia, M. Hayden, 2016, Circulation research.