I. Ho

发表

CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis.

Charles M Perou, Matthew D. Smith, Feng Bai, 2009, Cancer cell.

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases

I. Ho, Yanbao Xiong, A. Medvedev, 2015, Journal of Innate Immunity.

Variable effects of transgenic c-Maf on autoimmune diabetes.

L. Glimcher, M. Pauza, D. Lo, 2001, Diabetes.

Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling.

P. Oettgen, I. Ho, W. Ni, 2005, The Journal of clinical investigation.

Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity

R. Locksley, I. Ho, Hong-Erh Liang, 2011, Nature Immunology.

Cysteinyl Leukotrienes Regulate Th2 Cell-Dependent Pulmonary Inflammation1

D. Friend, K. Austen, I. Ho, 2006, The Journal of Immunology.

Th2 Cytokine Gene Locus Identifies Ets-1 as a Novel Regulator of the Phylogenetic and Functional Analysis

I. Ho, D. Vercelli, R. Grenningloh, 2010 .

Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses

I. Ho, R. Grenningloh, B. Kang, 2005, The Journal of experimental medicine.

A T-cell-specific CD154 transcriptional enhancer located just upstream of the promoter

I. Ho, A. Genin, M. Brunner, 2008, Genes and Immunity.

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells1

V. Kuchroo, Hulin Jin, A. Awasthi, 2009, The Journal of Immunology.

Transcriptional Regulation of GATA-3 by an Intronic Regulatory Region and Fetal Liver Zinc Finger Protein 11

I. Ho, E. Hwang, A. Choi, 2002, The Journal of Immunology.

SUMOylation attenuates c‐Maf‐dependent IL‐4 expression

I. Ho, Hsiao-Wei Tsao, Li-Fang Wang, 2010, European journal of immunology.

c‐Maf interacts with c‐Myb to down‐regulate Bcl‐2 expression and increase apoptosis in peripheral CD4 cells

Siying Peng, M. Pauza, I. Ho, 2007, European journal of immunology.

GATA-3 Regulates the Homeostasis and Activation of CD8+ T Cells

S. Pai, I. Ho, Tzong-Shyuan Tai, 2013, The Journal of Immunology.

A Novel Group of Phospholipase A2s Preferentially Expressed in Type 2 Helper T Cells*

L. Glimcher, K. Austen, I. Ho, 2001, The Journal of Biological Chemistry.

Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts

S. Ryter, Bo Sun, K. Tsoyi, 2022, Scientific Reports.

GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation

S. Pai, I. Ho, Tzong-Shyuan Tai, 2009, Nature Reviews Immunology.

GATA-3 Regulates the Development and Function of Invariant NKT Cells1

G. Besra, S. Pai, I. Ho, 2006, The Journal of Immunology.

Distinct Structural Requirements of GATA-3 for the Regulation of Thymocyte and Th2 Cell Differentiation1

S. Pai, E. Parisini, I. Ho, 2008, The Journal of Immunology.

A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis.

J. W. Rooney, B. Spiegelman, L. Glimcher, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Induced Colitis and Susceptibility to Dextran Sulfate Sodium PTPN22 Modulates Macrophage Polarization

I. Ho, Hsiao-Wei Tsao, S. Miaw, 2013 .

Genes that regulate interleukin-4 expression in T cells.

S. Szabo, L. Glimcher, I. Ho, 1997, Current opinion in immunology.

Transcriptional regulation of th2 differentiation by inducible costimulator.

U. Dianzani, R. Flavell, R. Nurieva, 2003, Immunity.

The Ta2 Nuclear Protein Binding Site from the Human T Cell Receptor ct Enhancer Functions as Both a T Cellspecific Transcriptional Activator and Repressor

I. Ho, 2003 .

Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements

I. Ho, J. Leiden, 1990, Molecular and cellular biology.

Ets-1 Maintains IL-7 Receptor Expression in Peripheral T Cells

C. Brander, N. Frahm, D. Kaufmann, 2011, The Journal of Immunology.

Ets1 Promotes the Differentiation of Post-Selected iNKT Cells through Regulation of the Expression of Vα14Jα18 T Cell Receptor and PLZF

I. Ho, Huang-Yu Yang, Yu-Wen Huang, 2021, International Journal of Molecular Sciences.

A Repressor of GATA-Mediated Negative Feedback Mechanism of T Cell Activation1

Ian A. White, I. Ho, S. Miaw, 2004, The Journal of Immunology.

A stage‐specific functional role of the leucine zipper transcription factor c‐Maf in lung Th2 cell differentiation

P. Galle, H. Lehr, I. Ho, 2004, European journal of immunology.

Marking IL-4-producing cells by knock-in of the IL-4 gene.

L. Glimcher, M. Kaplan, I. Ho, 1999, International immunology.

IL-2 Receptor β-Chain Signaling Controls Immunosuppressive CD4+ T Cells in the Draining Lymph Nodes and Lung during Allergic Airway Inflammation In Vivo

M. Neurath, H. Lehr, P. Scholtes, 2008, The Journal of Immunology.

The Proto-Oncogene c-maf Is Responsible for Tissue-Specific Expression of Interleukin-4

Laurie H Glimcher, J. W. Rooney, L. Glimcher, 1996, Cell.

Zinc Finger Protein 1 Intronic Regulatory Region and Fetal Liver Transcriptional Regulation of GATA-3 by an

I. Ho, E. Hwang, A. Choi, 2013 .

Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination.

P. Thompson, I. Ho, E. Weerapana, 2019, JCI insight.

Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter

I. Ho, Hsiao-Wei Tsao, R. Grenningloh, 2013, Proceedings of the National Academy of Sciences.

m(en)TOR(ing) differentiating T helper cells.

I. Ho, 2009, Immunity.

Differential impacts of TNFα inhibitors on the transcriptome of Th cells

I. Ho, Hui-Ying Weng, Beverly Tomita, 2021, Arthritis Research & Therapy.

The transcription factor NFAT4 is involved in the generation and survival of T cells.

L. Glimcher, T. Hoey, M. Oukka, 1998, Immunity.

Regulation of thymocyte homeostasis by Fliz1

I. Ho, E. Hwang, 2002, Immunology.

Cell Differentiation for the Regulation of Thymocyte and Th 2 Distinct Structural Requirements of GATA-3

S. Pai, E. Parisini, I. Ho, 2007 .

Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer.

N. Bhat, C. Thompson, I. Ho, 1990, Science.

c-Rel delivers a one-two punch in Th1 cell differentiation.

S. Pai, I. Ho, 2002, The Journal of clinical investigation.

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Z. Werb, S. Pai, A. Ewald, 2008, Cancer cell.

Critical roles for transcription factor GATA-3 in thymocyte development.

S. Pai, L. Glimcher, I. Ho, 2003, Immunity.

Human GATA‐3: a lineage‐restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

S. Tsai, I. Ho, J. Leiden, 1991, The EMBO journal.

PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis.

P. Thompson, K. Tsoyi, I. Ho, 2021, Matrix biology : journal of the International Society for Matrix Biology.

A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22.

J. Norris, E. Karlson, V. Holers, 2016, JCI insight.

Regulation of IL-4 Expression in Immunity and Diseases.

I. Ho, S. Miaw, 2016, Advances in experimental medicine and biology.

Th 2 Cytokine Gene Locus Identifies Ets-1 as a Novel Regulator of the Phylogenetic and Functional Analysis

I. Ho, D. Vercelli, R. Grenningloh, 2010 .

Phylogenetic and Functional Analysis Identifies Ets-1 as a Novel Regulator of the Th2 Cytokine Gene Locus

I. Ho, D. Vercelli, R. Grenningloh, 2009, The Journal of Immunology.

Interleukin 4 inhibits TGF-β-induced-Foxp3+T cells and generates, in combination with TGF-β, Foxp3− effector T cells that produce interleukins 9 and 10

V. Kuchroo, R. Sobel, S. Khoury, 2008, Nature Immunology.

Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development.

Tiansen Li, L. Glimcher, I. Ho, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 and Reduces Colitis in Mice.

M. Neurath, H. Lehr, R. Atreya, 2017, Gastroenterology.

The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor

I. Ho, J. Leiden, I-Cheng Ho, 1990, The Journal of experimental medicine.

GATA-3 - not just for Th2 cells anymore.

S. Pai, I. Ho, 2007, Cellular & molecular immunology.

IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3− effector T cells

V. Kuchroo, R. Sobel, S. Khoury, 2008, Nature Immunology.

cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1

C. Y. Wang, G. Nabel, C. Thompson, 1992, Molecular and cellular biology.

Differential Regulation of IL-12 and IL-10 Gene Expression in Macrophages by the Basic Leucine Zipper Transcription Factor c-Maf Fibrosarcoma1

P. L. Bergsagel, Xiaojing Ma, I. Ho, 2002, The Journal of Immunology.

Maf Fibrosarcoma Basic Leucine Zipper Transcription Factor Gene Expression in Macrophages by the Differential Regulation of IL-12 and IL-10

P. L. Bergsagel, Xiaojing Ma, I. Ho, 2002 .

c-maf Promotes T Helper Cell Type 2 (Th2) and Attenuates Th1 Differentiation by Both Interleukin 4–dependent and –independent Mechanisms

L. Glimcher, D. Lo, I. Ho, 1998, The Journal of experimental medicine.

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

S. Pai, I. Ho, M. Truitt, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Transcription Tantalizing Times for T Cells

L. Glimcher, I. Ho, 2002, Cell.

An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines

Ian A. White, I. Ho, E. Hwang, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus.

I. Ho, J. Leiden, G. Morle, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

V. Kuchroo, Hulin Jin, A. Sharpe, 2009, Nature Immunology.

Peripheral T Cells Ets-1 Maintains Il-7 Receptor Expression In

C. Brander, N. Frahm, D. Kaufmann, 2022 .

The transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus

I. Ho, M. Ehlers, R. Grenningloh, 2009, The Journal of experimental medicine.

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines.

L. Glimcher, I. Ho, M. Grusby, 1999, Immunity.

A Critical Regulatory Role of Leucin Zipper Transcription Factor c-Maf in Th1-Mediated Experimental Colitis1

M. Neurath, P. Galle, H. Lehr, 2004, The Journal of Immunology.

Experimental Colitis Transcription Factor c-Maf in Th 1-Mediated A Critical Regulatory Role of Leucin Zipper

M. Neurath, P. Galle, H. Lehr, 2004 .

Role of Ets‐1 phosphorylation in the effector function of Th cells

B. Graves, I. Ho, R. Grenningloh, 2008, European journal of immunology.

Ets-1 is a negative regulator of Th17 differentiation

E. Bettelli, M. Oukka, I. Ho, 2007, The Journal of experimental medicine.

ROG Negatively Regulates T-Cell Activation but Is Dispensable for Th-Cell Differentiation

I. Ho, S. Miaw, B. Kang, 2005, Molecular and Cellular Biology.

The Cell Type-Specific Expression of the Murine IL-13 Gene Is Regulated by GATA-31

I. Ho, S. Miaw, H. Kishikawa, 2001, The Journal of Immunology.

ROG, repressor of GATA, regulates the expression of cytokine genes.

I. Ho, S. Miaw, H. Kishikawa, 2000, Immunity.

A T-cell-specific transcriptional enhancer element 3 ' of C . in the human T-cell receptor a locus

I. Ho, J. Leiden, G. Morle, 2022 .

Altered expression of protein tyrosine phosphatase, non-receptor type 22 isoforms in systemic lupus erythematosus

J. Cui, I. Ho, K. Costenbader, 2014, Arthritis Research & Therapy.

Tissue-specific regulation of cytokine gene expression.

S. Szabo, L. Glimcher, I. Ho, 1999, Cold Spring Harbor symposia on quantitative biology.

Interaction of Ets-1 with HDAC1 Represses IL-10 Expression in Th1 Cells

H. So, I. Ho, Gicheon Kim, 2012, The Journal of Immunology.

PTPN22 Modulates Macrophage Polarization and Susceptibility to Dextran Sulfate Sodium–Induced Colitis

I. Ho, Hsiao-Wei Tsao, S. Miaw, 2013, The Journal of Immunology.

E.: “A Summary of

Ajay N. Jain, Gene W. Yeo, C. Y. Wang, 1968 .

Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3

J. Segre, P. Meltzer, Chenwei Wang, 2006, The Journal of cell biology.

Reciprocal Regulation of C-Maf Tyrosine Phosphorylation by Tec and Ptpn22

I. Ho, Hsiao-Wei Tsao, S. Miaw, 2015, PloS one.

Citrullination and Neutrophil Extracellular Traps

I. Ho, N. Dwivedi, Hui‐Hsin Chang, 2017 .

Cutting Edge: Inhibition of the Retinoid X Receptor (RXR) Blocks T Helper 2 Differentiation and Prevents Allergic Lung Inflammation

I. Ho, F. Sinigaglia, R. Grenningloh, 2006, The Journal of Immunology.

This information is current as Inflammation Differentiation and Prevents Allergic Lung Receptor ( RXR ) Blocks T Helper 2 Cutting Edge : Inhibition of the Retinoid X

I. Ho, F. Sinigaglia, P. Panina-Bordignon, 2006 .

Clostridium perfringens septicemia with massive hemolysis.

I. Ho, D. Cheng, M. Yen, 1989, Scandinavian Journal of Infectious Diseases.

Itm2a, a Target Gene of GATA-3, Plays a Minimal Role in Regulating the Development and Function of T Cells

S. Pai, I. Ho, Tzong-Shyuan Tai, 2014, PloS one.

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα

C. Schiffer, P. Thompson, I. Ho, 2017, Science Immunology.

The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis

I. Ho, N. Dwivedi, A. Nicholas, 2015, Arthritis & rheumatology.

PTPN22.6, a Dominant Negative Isoform of PTPN22 and Potential Biomarker of Rheumatoid Arthritis

M. Weinblatt, N. Shadick, I. Ho, 2012, PloS one.

Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis

E. Karlson, I. Ho, J. Sparks, 2019, bioRxiv.

Ets1 regulates the differentiation and function of iNKT cells through both Pointed domain-dependent and domain-independent mechanisms

P. Oettgen, I. Ho, Hsiao-Wei Tsao, 2020, Cellular & Molecular Immunology.

ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis

I. Ho, Seung-Yeol Park, V. Hsu, 2019, Nature Communications.