I. Cózar-Castellano

发表

Lessons From the First Comprehensive Molecular Characterization of Cell Cycle Control in Rodent Insulinoma Cell Lines

B. Sicari, A. F. Stewart, D. Scott, 2008, Diabetes.

Low-density lipoprotein cholesterol suppresses apoptosis in human multiple myeloma cells

I. Cózar-Castellano, G. Perdomo, J. Tirado-Vélez, 2011, Annals of Hematology.

Cellular Mechanism Through Which Parathyroid Hormone–Related Protein Induces Proliferation in Arterial Smooth Muscle Cells: Definition of an Arterial Smooth Muscle PTHrP/p27kip1 Pathway

B. Sicari, A. F. Stewart, I. Cózar-Castellano, 2006, Circulation research.

Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice

I. Cózar-Castellano, A. Moreno, C. D. Lobatón, 2017, Marine drugs.

Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice

I. Cózar-Castellano, A. García-Ocaña, G. Perdomo, 2015, Journal of Physiology and Biochemistry.

Tissue-Specific Deletion of the Retinoblastoma Protein in the Pancreatic β-Cell Has Limited Effects on β-Cell Replication, Mass, and Function

A. F. Stewart, I. Cózar-Castellano, R. Vasavada, 2007, Diabetes.

Evaluation of beta-cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21cip.

A. F. Stewart, I. Cózar-Castellano, Matthew T. Weinstock, 2006, Diabetes.

Evaluation of -Cell Replication in Mice Transgenic for Hepatocyte Growth Factor and Placental Lactogen Comprehensive Characterization of the G1/S Regulatory Proteins Reveals Unique Involvement of p21

A. F. Stewart, I. Cózar-Castellano, Matthew T. Weinstock, 2005 .

Growth factors and beta cell replication.

I. Cózar-Castellano, R. Vasavada, N. Fiaschi-Taesch, 2006, The international journal of biochemistry & cell biology.

Mutant parathyroid hormone-related protein, devoid of the nuclear localization signal, markedly inhibits arterial smooth muscle cell cycle and neointima formation by coordinate up-regulation of p15Ink4b and p27kip1.

A. F. Stewart, I. Cózar-Castellano, K. Takane, 2009, Endocrinology.

Genetic deficiency of apolipoprotein D in the mouse is associated with nonfasting hypertriglyceridemia and hyperinsulinemia.

I. Cózar-Castellano, M. Jiménez-Palomares, D. Sanchez, 2011, Metabolism: clinical and experimental.

High glucose levels reduce fatty acid oxidation and increase triglyceride accumulation in human placenta.

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2013, American journal of physiology. Endocrinology and metabolism.

Epoxypukalide Induces Proliferation and Protects against Cytokine-Mediated Apoptosis in Primary Cultures of Pancreatic β-Cells

I. Cózar-Castellano, M. Jiménez-Palomares, G. Perdomo, 2013, PloS one.

Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

I. Cózar-Castellano, M. Ganfornina, J. Darias, 2020, Marine drugs.

Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme

I. Cózar-Castellano, M. Pablos, G. Perdomo, 2022, Frontiers in Endocrinology.

Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice.

S. Najjar, I. Cózar-Castellano, M. Leissring, 2018, Metabolism: clinical and experimental.

Hepatocyte growth factor gene therapy for islet transplantation

I. Cózar-Castellano, R. Vasavada, A. García-Ocaña, 2004, Expert opinion on biological therapy.

Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice

I. Cózar-Castellano, M. Leissring, C. D. Lobatón, 2020, Metabolism: clinical and experimental.

Hepatocyte growth factor is elevated in amniotic fluid from obese women and regulates placental glucose and fatty acid metabolism.

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2015, Placenta.

Hepatocyte growth factor is elevated in amniotic fluid from obese 1 women and regulates placental glucose and fatty acid metabolism

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2015 .

hIscA: a protein implicated in the biogenesis of iron-sulfur clusters.

I. Cózar-Castellano, J. Ávila, P. Martín-Vasallo, 2004, Biochimica et biophysica acta.

The Cell Cycle Inhibitory Protein p21cip Is Not Essential for Maintaining β-Cell Cycle Arrest or β-Cell Function In Vivo

A. F. Stewart, I. Cózar-Castellano, M. Haught, 2006, Diabetes.

Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1.

A. F. Stewart, I. Cózar-Castellano, K. Takane, 2004, Diabetes.

Molecular control of cell cycle progression in the pancreatic beta-cell.

A. F. Stewart, I. Cózar-Castellano, K. Takane, 2006, Endocrine reviews.

Molecular engineering human hepatocytes into pancreatic beta cells for diabetes therapy

A. F. Stewart, I. Cózar-Castellano, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation

K. Kaestner, I. Cózar-Castellano, M. Leissring, 2022, Diabetologia.

Tissue-specific deletion of the retinoblastoma protein in the pancreatic beta-cell has limited effects on beta-cell replication, mass, and function.

A. F. Stewart, I. Cózar-Castellano, R. Vasavada, 2007, Diabetes.

Manipulation of Transmembrane Transport by Synthetic K+ Ionophore Depsipeptides and Its Implications in Glucose-Stimulated Insulin Secretion in β-Cells.

I. Cózar-Castellano, M. Barboiu, T. Torroba, 2019, Chemistry.

Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice

I. Cózar-Castellano, G. Perdomo, A. Díaz-Marrero, 2015, Islets.

Na+, K+-ATPase Isozyme Diversity; Comparative Biochemistry and Physiological Implications of Novel Functional Interactions

A. Mobasheri, I. Cózar-Castellano, M. Brownleader, 2000, Bioscience reports.

Cembranoids from Eunicea sp. enhance insulin-producing cells proliferation

I. Cózar-Castellano, J. Darias, G. Perdomo, 2018 .

Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease

M. Garcia-Alloza, I. Cózar-Castellano, M. Jiménez-Palomares, 2015, Psychoneuroendocrinology.

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

A. F. Stewart, D. Scott, I. Cózar-Castellano, 2010, Diabetes.

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

I. Cózar-Castellano, G. Perdomo, J. Tirado-Vélez, 2012, PloS one.

Intestinal Fructose and Glucose Metabolism in Health and Disease

I. Cózar-Castellano, G. Perdomo, B. Merino, 2019, Nutrients.

Glucose and Fatty Acid Metabolism in Placental Explants From Pregnancies Complicated With Gestational Diabetes Mellitus

I. Cózar-Castellano, G. Perdomo, J. Bartha, 2015, Reproductive Sciences.

Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme

I. Cózar-Castellano, M. Leissring, G. Perdomo, 2021, Biomedicines.

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human β-Cell Replication and Function In Vivo

A. F. Stewart, I. Cózar-Castellano, G. Harb, 2009, Diabetes.

Cyclin C stimulates β-cell proliferation in rat and human pancreatic β-cells.

I. Cózar-Castellano, E. Bernal-Mizrachi, M. Jiménez-Palomares, 2015, American journal of physiology. Endocrinology and metabolism.

Evolutionary Origin of Insulin-Degrading Enzyme and Its Subcellular Localization and Secretion Mechanism: A Study in Microglial Cells

C. Lillo, I. Cózar-Castellano, D. Sanchez, 2022, Cells.

miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

I. Cózar-Castellano, P. Cidad, S. Albinsson, 2021, Molecular metabolism.

Molecular Control of Cell Cycle Progression in the Pancreatic β-Cell

A. F. Stewart, I. Cózar-Castellano, K. Takane, 2006 .

Effects of Fasting and Feeding on Transcriptional and Posttranscriptional Regulation of Insulin-Degrading Enzyme in Mice

I. Cózar-Castellano, M. Leissring, G. Perdomo, 2021, Cells.

Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models

M. Garcia-Alloza, I. Cózar-Castellano, M. Jiménez-Palomares, 2014, PloS one.

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice

T. Spires-Jones, M. Garcia-Alloza, I. Cózar-Castellano, 2013, Psychoneuroendocrinology.

Insulin degrading enzyme is up-regulated in pancreatic β cells by insulin treatment.

I. Cózar-Castellano, A. Moreno, C. D. Lobatón, 2018, Histology and histopathology.

Expression and cellular localization of Na,K‐ATPase isoforms in the rat ventral prostate

A. Mobasheri, C. Foster, I. Cózar-Castellano, 2003, BJU international.

Pancreatic beta-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and beta-cell functional immaturity.

I. Cózar-Castellano, M. Leissring, P. Cidad, 2019, American journal of physiology. Endocrinology and metabolism.

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

M. Garcia-Alloza, I. Cózar-Castellano, M. Jiménez-Palomares, 2012, American journal of physiology. Endocrinology and metabolism.

Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality

I. Cózar-Castellano, F. Medina, A. Lechuga-Sancho, 2015, International journal of endocrinology.

Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation.

A. F. Stewart, I. Cózar-Castellano, K. Takane, 2004, Endocrinology.

The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.

A. F. Stewart, I. Cózar-Castellano, M. Haught, 2006, Diabetes.

Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice.

I. Cózar-Castellano, T. Torroba, G. Perdomo, 2023, Diabetes, obesity & metabolism.

Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice.

S. Najjar, I. Cózar-Castellano, M. Leissring, 2018, Metabolism: clinical and experimental.

Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer’s disease and brain aging

I. Cózar-Castellano, M. Ganfornina, Jingtao Lilue, 2023, Journal of Neuroinflammation.

Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice

I. Cózar-Castellano, A. García-Ocaña, Viviana Sánchez-Encinales, 2015, Journal of Physiology and Biochemistry.

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation

I. Cózar-Castellano, J. Darias, J. M. de la Rosa, 2018, Marine drugs.