A. Woodhead

发表

Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design.

Paul G Wyatt, Valerio Berdini, V. Berdini, 2008, Journal of medicinal chemistry.

From fragment to clinical candidate--a historical perspective.

Gianni Chessari, G. Chessari, A. Woodhead, 2009, Drug discovery today.

Recent developments in fragment-based drug discovery.

M. Congreve, G. Chessari, A. Woodhead, 2008, Journal of medicinal chemistry.

Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.

Gianni Chessari, Brent Graham, Christopher W Murray, 2010, Journal of medicinal chemistry.

Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function

Andrew J. Woodhead, Gianni Chessari, Brent Graham, 2012, Nature chemical biology.

Identification of novel p38alpha MAP kinase inhibitors using fragment-based lead generation.

Christopher W Murray, Alessandro Padova, Jayne Curry, 2005, Journal of medicinal chemistry.

Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design.

Gianni Chessari, Brent Graham, Jose Cosme, 2010, Journal of medicinal chemistry.

CHAPTER 4 – Structural biology and anticancer drug design

Dominic Tisi, Gianni Chessari, Andrew James Woodhead, 2008 .

Masseter muscle rigidity and the role of DNA analysis to confirm malignant hyperthermia susceptibility

A. Woodhead, N. Pollock, K. Stowell, 2019, Anaesthesia and intensive care.

Recent Developments in Fragment-Based Drug Discovery

M. Congreve, G. Chessari, A. Woodhead, 2008 .

Fragment-to-Lead Medicinal Chemistry Publications in 2021.

W. Jahnke, I. D. de Esch, A. Woodhead, 2023, Journal of medicinal chemistry.

Hsp90 inhibition by AT13387 modulates growth factor and cytokine stimulated cell signalling in multiple cell lines.

C. Murray, L. Fazal, J. Lyons, 2007 .

Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.

M. Congreve, C. Murray, G. Chessari, 2010, Journal of medicinal chemistry.