P. Allen

S. Boncompagni, F. Protasi, C. Franzini-armstrong, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Kinetic studies of Ca2+ release from sarcoplasmic reticulum of normal and malignant hyperthermia susceptible pig muscles.

P. Allen, J. Ryan, N. Ikemoto, 1984, Biochimica et biophysica acta.

Myoplasmic Calcium Changes Precede Metabolic and Clinical Signs of Porcine Malignant Hyperthermia

P. Allen, J. Ryan, José R Lopez, 1994, Anesthesia and analgesia.

Effects of PARP inhibition on drug and Fas-induced apoptosis in leukaemic cells.

P. Allen, A. Newland, S. Kelsey, 1999, Advances in experimental medicine and biology.

Inhibition of FAS/FAS-ligand does not block chemotherapy-induced apoptosis in drug sensitive and resistant cells.

P. Allen, A. Newland, S. Kelsey, 1999, Advances in experimental medicine and biology.

The creatine kinase system in normal and diseased human myocardium.

R. Shemin, B. Lorell, J. Ingwall, 1985, The New England journal of medicine.

Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.

P. Allen, J. Kalil, V. Dzau, 2005, The American journal of pathology.

ENHANCED EXCITATION-COUPLED CALCIUM ENTRY IN MYOTUBES IS ASSOCIATED WITH EXPRESSION OF RYR 1 MH MUTATIONS

P. Allen, I. Pessah, José R Lopez, 2007 .

Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.

M. Komajda, P. Allen, L. Carrier, 1991, The Journal of clinical investigation.

Functional and Biochemical Properties of Ryanodine Receptor Type 1 Channels from Heterozygous R163C Malignant Hyperthermia-Susceptible Mice

P. Allen, I. Pessah, José R Lopez, 2011, Molecular Pharmacology.

Conformational activation of Ca2+ entry by depolarization of skeletal myotubes.

K. Beam, J. Fessenden, P. Allen, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Heart and Skeletal Muscle Are Targets of Dengue Virus Infection

Keith Mansfield, Irene Bosch, K. Martin, 2010, The Pediatric infectious disease journal.

Structural characterization of the RyR1-FKBP12 interaction.

Paul D Allen, Montserrat Samsó, Xiaohua Shen, 2006, Journal of molecular biology.

Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM

Montserrat Samsó, Terence Wagenknecht, T. Wagenknecht, 2005, Nature Structural &Molecular Biology.

Functional hyperactivity of monocytes after bone marrow transplantation: possible relevance for the development of post-transplant complications or relapse.

P. Allen, P. Collins, A. Goldstone, 1995, Bone marrow transplantation.

TRPCs: Influential Mediators in Skeletal Muscle

P. Allen, Eun Hui Lee, S. Jeong, 2020, Cells.

Identification of a region of RyR1 that participates in allosteric coupling with the alpha(1S) (Ca(V)1.1) II-III loop.

J. Nakai, K. Beam, P. Allen, 2002, The Journal of biological chemistry.

Inhibition of autophagy abrogates tumour necrosis factor α induced apoptosis in human T‐lymphoblastic leukaemic cells

P. Allen, R. Dourmashkin, A. Newland, 1997, British journal of haematology.

Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep+ hybrid amplicon vector

X. Breakefield, P. Allen, S. Camp, 2003, Gene Therapy.

Herpes Simplex Virus Type 1/Adeno-Associated Virus rep+ Hybrid Amplicon Vector Improves the Stability of Transgene Expression in Human Cells by Site-Specific Integration

X. Breakefield, P. Allen, S. Camp, 2002, Journal of Virology.

25-Dihydroxyvitamin D 3 Protects Human Leukemic Cells from Tumor Necrosis Factor-induced Apoptosis via Inactivation of Cytosolic Phospholipase A 2

Jiang, Stephen, P. Allen, 2006 .

Effects of dantrolene on myoplasmic free [Ca2+] measured in vivo in patients susceptible to malignant hyperthermia.

P. Allen, J. R. López, M. López, 1992, Anesthesiology.

Etoposide‐mediated deregulation of the G2M checkpoint in myeloid leukaemic cell lines results in loss of cell survival

P. Allen, M. Cummings, K. Higginbottom, 2002, British journal of haematology.

Understanding malignant hyperthermia: each move forward opens our eyes to the distance left to travel.

P. Allen, R. Dirksen, J. R. López, 2019, British journal of anaesthesia.

Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak

C. Ward, T. Molinski, P. Allen, 2011, Proceedings of the National Academy of Sciences.

Leaky "feet" and sudden death.

P. Allen, 2002, Circulation research.

Maurocalcine and Peptide A Stabilize Distinct Subconductance States of Ryanodine Receptor Type 1, Revealing a Proportional Gating Mechanism*

Michel De Waard, Paul D Allen, M. Ronjat, 2003, The Journal of Biological Chemistry.

Homer Regulates Gain of Ryanodine Receptor Type 1 Channel Complex*

P. Worley, P. Allen, I. Pessah, 2002, The Journal of Biological Chemistry.

Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line.

J. Fessenden, P. Allen, I. Pessah, 2000, Biophysical journal.

Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug‐induced apoptosis in human leukaemic cells: a possible novel mechanism of regulating drug resistance

M. Macey, P. Allen, A. Newland, 1997, British journal of haematology.

Mononuclear Cells from Dedifferentiation of Mouse Myotubes Display Remarkable Regenerative Capability

D. Ingber, R. Mannix, Xiaoyin Xu, 2014, Stem cells.

Microarray gene expression profiles in dilated and hypertrophic cardiomyopathic end-stage heart failure.

George C Tseng, Paul D Allen, Lameh Fananapazir, 2002, Physiological genomics.

Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes*

P. Allen, H. Querfurth, José R Lopez, 2004, Journal of Biological Chemistry.

Molecular cloning and characterization of a human brain ryanodine receptor 1

J. Nakai, T. Kita, P. Allen, 1997, FEBS letters.

Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.

S. Izumo, P. Allen, Toshiyuki Takahashi, 1992, Circulation research.

N-terminal Region of FKBP12 Is Essential for Binding to the Skeletal Ryanodine Receptor*

D. H. Kim, S. Eom, P. Allen, 2004, Journal of Biological Chemistry.

Not all sudden death is the same.

P. Allen, 2003, Circulation research.

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis.

P. Allen, B. Bertrand, R. Tunwell, 1996, The Biochemical journal.

Site-Specific Integration Transgene Expression in Human Cells by Amplicon Vector Improves the Stability of Hybrid + rep 1 / Adeno-Associated Virus Herpes Simplex Virus Type

X. Breakefield, P. Allen, S. Camp, 2002 .

Abnormal intracellular calcium handling, a major cause of systolic and diastolic dysfunction in ventricular myocardium from patients with heart failure.

J. Gwathmey, P. Allen, W. Grossman, 1990, Circulation.

Ryanodine Receptor Type 1 (RyR1) Mutations C4958S and C4961S Reveal Excitation-coupled Calcium Entry (ECCE) Is Independent of Sarcoplasmic Reticulum Store Depletion*

K. Beam, P. Allen, I. Pessah, 2005, Journal of Biological Chemistry.

RyR1 and RyR3 isoforms provide distinct intracellular Ca2+ signals in HEK 293 cells.

Peter Lipp, Paul D Allen, Vincenzo Sorrentino, 2002, Journal of cell science.

RyR 1 and RyR 3 isoforms provide distinct intracellular Ca 2 + signals in HEK 293 cells

P. Lipp, M. Bootman, P. Allen, 2022 .

Expression of dihydropyridine receptor (Ca2+ channel) and calsequestrin genes in the myocardium of patients with end-stage heart failure.

W Grossman, F J Schoen, F. Schoen, 1992, The Journal of clinical investigation.

The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development

E. Lakatta, K. Boheler, M. Stern, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Dysfunction of Diastolic (Ca 2+ ) in Cardiomyocytes Isolated From Chagasic Patients

P. Allen, A. Mijares, R. Espinosa, 2011 .

Dysfunction of Diastolic [Ca] in Cardiomyocytes Isolated From Chagasic Patients

P. Allen, José R Lopez, A. Mijares, 2017 .

Influence of isoproterenol and ouabain on excitation-contraction coupling, cross-bridge function, and energetics in failing human myocardium.

N. Alpert, G. Hasenfuss, H. Just, 1996, Circulation.

Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes.

Paul D Allen, P. Allen, H. Querfurth, 2004, The Journal of biological chemistry.

Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.

J. Nakai, K. Beam, F. Protasi, 2002, Biophysical journal.

Calcium Transients in 1B5 Myotubes Lacking Ryanodine Receptors Are Related to Inositol Trisphosphate Receptors*

M. Estrada, P. Allen, J. Liberona, 2001, The Journal of Biological Chemistry.

Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.

N. Alpert, G. Hasenfuss, P. Allen, 1992, Circulation research.

Modulation of CD13 expression during retinoic acid-induced differentiation of HL60 cells.

P. Allen, A. Newland, K. Razak, 1994, Leukemia research.

Best practice BioBanking of human heart tissue

R. Cooke, P. Allen, A. Keogh, 2015, Biophysical Reviews.

Blood-Based Biomarkers of Aggressive Prostate Cancer

J. Richie, G. Steele, P. Allen, 2012, PloS one.

Transmembrane Redox Sensor of Ryanodine Receptor Complex*

P. Allen, I. Pessah, W. Feng, 2000, The Journal of Biological Chemistry.

Impaired Orai1-mediated Resting Ca2+ Entry Reduces the Cytosolic [Ca2+] and Sarcoplasmic Reticulum Ca2+ Loading in Quiescent Junctophilin 1 Knock-out Myotubes*

H. Takeshima, P. Allen, Jianjie Ma, 2010, The Journal of Biological Chemistry.

Biochemical characterization of the Na+/K+-ATPase isoforms in human heart

P. Allen, P. Lechat, S. Decollogne, 1994 .

Cellular distribution and pharmacological sensitivity of low Km cyclic nucleotide phosphodiesterase isozymes in human cardiac muscle from normal and cardiomyopathic subjects.

R. Bentley, J. Etzler, P. Allen, 1990, Second messengers and phosphoproteins.

Gene Dose Influences Cellular and Calcium Channel Dysregulation in Heterozygous and Homozygous T4826I-RYR1 Malignant Hyperthermia-susceptible Muscle*

P. Allen, I. Pessah, José R Lopez, 2011, The Journal of Biological Chemistry.

Neuromuscular development in the avian paralytic mutant crooked neck dwarf (cn/cn): further evidence for the role of neuromuscular activity in motoneuron survival

P. Wenner, R. Oppenheim, D. McKemy, 1997, The Journal of comparative neurology.

Contractile protein function in failing and nonfailing human myocardium.

N. Alpert, G. Hasenfuss, H. Just, 1992, Basic research in cardiology.

Amino Acid Residues Gln4020 and Lys4021 of the Ryanodine Receptor Type 1 Are Required for Activation by 4-Chloro-m-cresol*

J. Fessenden, P. Allen, I. Pessah, 2006, Journal of Biological Chemistry.

FKBP12 Binding to RyR1 Modulates Excitation-Contraction Coupling in Mouse Skeletal Myotubes*

P. Allen, Eun Hui Lee, G. Ávila, 2003, Journal of Biological Chemistry.

Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca2+ release channel/ryanodine receptors

P. Allen, I. Pessah, H. Rochat, 2000, FEBS letters.

Homo-dimerization of RyR1 C-terminus via charged residues in random coils or in an α-helix

P. Allen, Eun Hui Lee, 2007, Experimental & Molecular Medicine.

Ryanodine receptor point mutant E4032A reveals an allosteric interaction with ryanodine

Yaming Wang, J. Fessenden, P. Allen, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Interplay between intra- and extracellular calcium ions.

D. H. Kim, P. Allen, Eun Hui Lee, 2006, Molecules and cells.

Alpha2delta1 dihydropyridine receptor subunit is a critical element for excitation-coupled calcium entry but not for formation of tetrads in skeletal myotubes.

K. Beam, C. Haarmann, C. Franzini-armstrong, 2008, Biophysical journal.

Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle

E. Ríos, P. Allen, Mónika Sztretye, 2013, The Journal of physiology.

Dynamics of transgene expression in human glioblastoma cells mediated by herpes simplex virus/adeno-associated virus amplicon vectors.

D. Louis, X. Breakefield, Yaming Wang, 2002, Human gene therapy.

Comparison of contractile state and myosin isozymes of rat right and left ventricular myocardium.

P. Allen, A. Blaustein, O. H. Bing, 1987, Journal of molecular and cellular cardiology.

Ca2+ activation of RyR1 is not necessary for the initiation of skeletal-type excitation-contraction coupling.

K. Beam, P. Allen, I. Pessah, 2002, Biophysical journal.

Troponin T isoform expression in the normal and failing human left ventricle: a correlation with myofibrillar ATPase activity.

P. Allen, A. E. Oakeley, P. Anderson, 1992, Basic research in cardiology.

Erratum: Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with end-stage heart failure due to ischemic versus dilated cardiomyopathy (Circulation Research (1992) 71 (18-26))

A. Marks, S. Izumo, P. Allen, 1992 .

8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblastic leukemia cells to TNFalpha-induced apoptosis is via inactivation of NF-kappaB.

Y. Yin, P. Allen, A. Newland, 2001, Leukemia research.

Induction of surface tumor necrosis factor (TNF) expression and possible facilitation of surface TNF release from human monocytic cells by granulocyte-macrophage colony-stimulating factor or gamma interferon in combination with 1,25-dihydroxyvitamin D3.

M. Macey, P. Allen, A. Newland, 1993, Experimental hematology.

Measurements of [Ca2+]i in Skeletal Muscle of Malignant Hyperthermic Swine

P. Allen, José R Lopez, F. Sréter, 1985 .

Binding to Ia protects an immunogenic peptide from proteolytic degradation.

P. Allen, P. Allen, D. Donermeyer, 1989, Journal of immunology.

Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance

K. Beam, Yao Dong, P. Allen, 2023, The Journal of biological chemistry.

Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia

P. Allen, Xiaochen Liu, M. Shaw, 2020, The Journal of Biological Chemistry.

EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine.

P. Allen, J. Ryan, F. Sréter, 1992, Anesthesiology.

Measurement of Intra-SR [Ca 2+] Reveals Changes in SR Ca 2+ Permeability During Intracellular Ca 2+ Release in Skeletal Muscle

E. Ríos, P. Allen, Mónika Sztretye, 2011 .

Myosin-induced acute myocarditis is a T cell-mediated disease.

P. Allen, P. Allen, P M Allen, 1991, Journal of immunology.

Apparent magnetic energy-barrier distribution in horse-spleen ferritin : Evidence for multiple interacting magnetic entities per ferrihydrite nanoparticle

P. Allen, K. V. Rao, T. Pierre, 2001 .

Negative inotropic and relaxant effects of cocaine on myopathic human ventricular myocardium and epicardial coronary arteries in vitro.

P. Allen, K. Morgan, J. Morgan, 1993, Cardiovascular Research.

Enhanced Excitation-Coupled Calcium Entry in Myotubes Expressing Malignant Hyperthermia Mutation R163C Is Attenuated by Dantrolene

P. Allen, I. Pessah, M. Samsó, 2008, Molecular Pharmacology.

Ablation of Skeletal Muscle Triadin Impairs FKBP12/RyR1 Channel Interactions Essential for Maintaining Resting Cytoplasmic Ca2+*

T. Molinski, P. Allen, I. Pessah, 2010, The Journal of Biological Chemistry.

Adult muscle 'stem' cells can be sustained in culture as free-floating myospheres.

P. Allen, C. Vacanti, Zhong Yang, 2010, Experimental cell research.

Type 1 and type 3 ryanodine receptors generate different Ca(2+) release event activity in both intact and permeabilized myotubes.

F. Protasi, P. Allen, I. Pessah, 2001, Biophysical journal.

Expression of ryanodine receptor RyR3 produces Ca2+ sparks in dyspedic myotubes

F. Protasi, Yaming Wang, P. Allen, 2000, The Journal of physiology.

RyR 1 mediated Ca 2 + leak and Ca 2 + entry determine resting intracellular Ca 2 + in skeletal myotubes

T. Molinski, P. Allen, I. Pessah, 2010 .

Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor

K. Beam, T. Molinski, P. Allen, 2012, Proceedings of the National Academy of Sciences.

Unravelling the unseen metabolic changes in patients with malignant hyperthermia

P. Allen, V. Kaura, Leon Chang, 2021, Canadian Journal of Anesthesia/Journal canadien d'anesthésie.