C. Chien

发表

Involvement of c-Jun N-terminal kinase in G2/M arrest and FasL-mediated apoptosis induced by a novel indoloquinoline derivative, IQDMA, in K562 cells.

Yeh-long Chen, Sheng-Huei Yang, C. Chien, 2007, Leukemia research.

Induction of G2/M phase arrest and apoptosis by a novel indoloquinoline derivative, IQDMA, in K562 cells

Yeh-long Chen, Sheng-Huei Yang, C. Chien, 2006 .

Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDA, in chronic myeloid leukemia (K562) cells

Sheng-Huei Yang, C. Chien, Shinne‐ren Lin, 2006, Molecular and Cellular Biochemistry.

A novel indoloquinoline derivative, IQDMA, induces S-phase arrest and apoptosis in promyelocytic leukemia HL-60 cells

Yeh-long Chen, Sheng-Huei Yang, C. Chien, 2006, Cell Biology and Toxicology.

Endothelin-1 Expression Associated with Lipid Peroxidation and Nuclear Factor-&kgr;B Activation in Type 2 Diabetes Mellitus Patients with Angiopathy and Limb Amputation

Ching‐Jen Wang, Feng-Sheng Wang, Y. Kuo, 2016, Plastic and reconstructive surgery.

Antimetastatic potential of cardiotoxin III involves inactivation of PI3K/Akt and p38 MAPK signaling pathways in human breast cancer MDA-MB-231 cells.

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2012, Life sciences.

Furano-1,2-Naphthoquinone Inhibits Src and PI3K/Akt Signaling Pathways in Ca9-22 Human Oral Squamous Carcinoma Cells

Yeh-long Chen, C. Chien, Long-Sen Chang, 2014, Integrative cancer therapies.

Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells.

Sheng-Huei Yang, C. Chien, Shinne‐ren Lin, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Cardiotoxin III induces c‐jun N‐terminal kinase‐dependent apoptosis in HL‐60 human leukaemia cells

Sheng-Huei Yang, C. Chien, Long-Sen Chang, 2008, Cell biochemistry and function.

Involvement of c-jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by cardiotoxin III (Naja naja atra) in K562 leukemia cells.

Sheng-Huei Yang, C. Chien, Long-Sen Chang, 2007, Toxicon : official journal of the International Society on Toxinology.

MECHANISMS OF CARDIOTOXIN III‐INDUCED APOPTOSIS IN HUMAN COLORECTAL CANCER COLO205 CELLS

Sheng-Huei Yang, C. Chien, Shinne‐ren Lin, 2006, Clinical and experimental pharmacology & physiology.

Induction of apoptosis in human leukemia K562 cells by cardiotoxin III.

T. Hour, Sheng-Huei Yang, C. Chien, 2005, Life sciences.

Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells.

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2010, Toxicon : official journal of the International Society on Toxinology.

Adipose-Derived Stem Cell Modulation of T-Cell Regulation Correlates with Heme Oxgenase-1 Pathway Changes

Ching‐Jen Wang, Y. Kuo, C. Chien, 2016, Plastic and reconstructive surgery.

Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress

H. Dahms, C. Chien, Chien-Chih Chiu, 2018, International journal of molecular sciences.

Recipient Adipose-Derived Stem Cells Enhance Recipient Cell Engraftment and Prolong Allotransplant Survival in a Miniature Swine Hind-Limb Model

Y. Kuo, C. Chien, Chien-Chang Chen, 2017, Cell transplantation.

INVOLVEMENT OF BOTH ENDOPLASMIC RETICULUM‐ AND MITOCHONDRIA‐DEPENDENT PATHWAYS IN CARDIOTOXIN III‐INDUCED APOPTOSIS IN HL‐60 CELLS

Sheng-Huei Yang, C. Chien, Long-Sen Chang, 2008, Clinical and experimental pharmacology & physiology.

Cardiotoxin III‐induced apoptosis is mediated by Ca2+‐dependent caspase‐12 activation in K562 cells

Sheng-Huei Yang, C. Chien, Long-Sen Chang, 2008, Journal of biochemical and molecular toxicology.

Hyaluronic Acid–Povidone-Iodine Compound Facilitates Diabetic Wound Healing in a Streptozotocin-Induced Diabetes Rodent Model

Ching‐Jen Wang, Y. Kuo, C. Chien, 2019, Plastic and reconstructive surgery.

Novel indoloquinoline derivative, IQDMA, suppresses STAT5 phosphorylation and induces apoptosis in HL-60 cells.

Yeh-long Chen, C. Chien, Long-Sen Chang, 2008, Chemico-biological interactions.

Phytochemical naphtho[1,2-b] furan-4,5‑dione induced topoisomerase II-mediated DNA damage response in human non-small-cell lung cancer.

Yeh-long Chen, C. Chien, Chien-Chih Chiu, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Furano‐1,2‐naphthoquinone inhibits EGFR signaling associated with G2/M cell cycle arrest and apoptosis in A549 cells

S. R. Lin, C. Chien, L. Chang, 2010, Cell biochemistry and function.

Naphtho[1,2-b]furan-4,5-dione induces apoptosis of oral squamous cell carcinoma: involvement of EGF receptor/PI3K/Akt signaling pathway.

Yeh-long Chen, C. Chien, Long-Sen Chang, 2010, European journal of pharmacology.

Naphtho[1,2-b]furan-4,5-dione disrupts Janus kinase-2 and induces apoptosis in breast cancer MDA-MB-231 cells.

Yeh-long Chen, C. Chien, Long-Sen Chang, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation.

Yeh-long Chen, C. Chien, Long-Sen Chang, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Naphtho[1,2-b]furan-4,5-dione inactivates EGFR and PI3K/Akt signaling pathways in human lung adenocarcinoma A549 cells.

Yeh-long Chen, C. Chien, Long-Sen Chang, 2010, Life sciences.

Half-sandwich Ru(η6-p-cymene) complexes featuring pyrazole appended ligands: Synthesis, DNA binding and in vitro cytotoxicity.

M. Tsai, C. Chien, R. Karvembu, 2019, Journal of inorganic biochemistry.

Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation.

C. Chien, Chih-Ming Lu, Long-Sen Chang, 2009, Life sciences.

JNK and ERK mitogen-activated protein kinases mediate THDA-induced apoptosis in K562 cells

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2008, Cell Biology and Toxicology.

Up-regulation of Bax and endonuclease G, and down-modulation of Bcl-XL involved in cardiotoxin III-induced apoptosis in K562 cells

C. Chien, Shinne‐ren Lin, Yi-Hsiung Lin, 2006, Experimental & Molecular Medicine.

Down-regulation of the JAK2/PI3K-mediated signaling activation is involved in Taiwan cobra cardiotoxin III-induced apoptosis of human breast MDA-MB-231 cancer cells.

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2010, Toxicon : official journal of the International Society on Toxinology.

Structural basis for targeting T:T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA.

C. Chien, S. Zimmerman, Cheng-Chung Chang, 2020, Journal of the American Chemical Society.

Structure-Based Stabilization of Non-native Protein–Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design

K. Kehn-Hall, U. Jeng, Shih-Chao Lin, 2020, Journal of medicinal chemistry.

Novel indoloquinoline derivative, IQDMA, inhibits STAT5 signaling associated with apoptosis in K562 cells

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2008, Journal of biochemical and molecular toxicology.

Induction of G2/M phase arrest and apoptosis by a novel indoloquinoline derivative, IQDMA, in K562 cells

C. Chien, Chih-Ming Lu, Shinne‐ren Lin, 2006 .

CARDIOTOXIN III INDUCES APOPTOSIS IN K562 CELLS THROUGH A MITOCHONDRIAL‐MEDIATED PATHWAY

C. Chien, Shinne‐ren Lin, Zchong‐Zcho Wu, 2005, Clinical and experimental pharmacology & physiology.

Cardiotoxin III induces apoptosis in T24 cells via reactive oxygen species‐independent mitochondrial death pathway

C. Chien, Shinne‐ren Lin, Mei-Chin Lu, 2004 .

Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3‐kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin III‐treated A549 cells

C. Chien, Shinne‐ren Lin, Jung-Chen Su, 2010, Clinical and experimental pharmacology & physiology.

Effects of cardiotoxin III on expression of genes and proteins related to G2/M arrest and apoptosis in K562 cells

C. Chien, Shinne‐ren Lin, Yung-Ning Yang, 2007, Molecular and Cellular Biochemistry.

Effects of cardiotoxin III on NF-kappaB function, proliferation, and apoptosis in human breast MCF-7 cancer cells.

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2009, Oncology research.

Inactivation of epidermal growth factor receptor and downstream pathways in oral squamous cell carcinoma Ca9-22 cells by cardiotoxin III from Naja naja atra.

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2009, Journal of natural products.