Yasuaki Yamada

发表

Inactivation of p14 ARF in Adult T cell Leukemia/ Lymphoma

M. Tomonaga, T. Matsuyama, T. Kohno, 2007 .

Inactivation of p14ARF as a key event for the progression of adult T cell leukemia/lymphoma.

M. Tomonaga, T. Matsuyama, T. Kohno, 2007, Leukemia research.

Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency.

M. Kusunoki, Yasuaki Yamada, S. Kamihira, 2005, International journal of oncology.

Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma.

H. Koeffler, Yang Yang, H. Taguchi, 2006, Leukemia research.

Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL.

M. Tomonaga, N. Mori, Yasuaki Yamada, 2003, Biochemical and biophysical research communications.

The methylthioadenosine phosphorylase gene is frequently co‐deleted with the p16INK4a gene in acute type adult T‐cell leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1998, International journal of cancer.

Constitutive Activation of NF-κB in Primary Adult T-Cell Leukemia Cells

M. Tomonaga, N. Mori, N. Yamamoto, 1999 .

Constitutive Activation Of Nf- κ B In Primary Adult T-cell Leukemia Cells

M. Tomonaga, N. Mori, N. Yamamoto, 1999 .

Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma.

K. Ohshima, R. Ueda, K. Yamaguchi, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Frequency of eosinophilia in adult T‐cell leukemia/lymphoma

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1992, Cancer.

Relationships of diverse apoptotic death process patterns to mitochondrial membrane potential (Δψm) evaluated by three-parameter flow cytometric analysis

Yasuaki Yamada, S. Kamihira, K. Nagai, 2012, Cytotechnology.

Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1-transformed T cells.

K. Matsushima, Yasuaki Yamada, S. Kamihira, 2002, Blood.

Kunio transformed T cells − leukemia virus type 1 Frequent expression of CCR 4 in adult T-cell leukemia and human T-cell

K. Matsushima, Yasuaki Yamada, S. Kamihira, 2002 .

Title Screening for genetic heterogeneity in the interferon sensitivity determining region of the hepatitis C virus genome by polymerase chain reaction with melting curve analysis

Naoko, Sugahara, Yasuaki Yamada, 2017 .

Screening for genetic heterogeneity in the interferon sensitivity determining region of the hepatitis C virus genome by polymerase chain reaction with melting curve analysis

Yasuaki Yamada, S. Kamihira, K. Sugahara, 2008, Clinical chemistry and laboratory medicine.

Rapid Detection and Evaluation of Clinical Characteristics of Emerging Multiple-Drug-Resistant Gram-Negative Rods Carrying the Metallo-β-Lactamase GeneblaIMP

Yasuaki Yamada, S. Kamihira, S. Kohno, 1998, Antimicrobial Agents and Chemotherapy.

Resveratrol Induces Downregulation in Survivin Expression and Apoptosis in HTLV-1-Infected Cell Lines: A Prospective Agent for Adult T Cell Leukemia Chemotherapy

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2002, Nutrition and cancer.

Clinical and bacteriological characteristics of IMP-type metallo-beta-lactamase-producing Pseudomonas aeruginosa.

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Restricted expression of tumor necrosis factor-related apoptosis-inducing ligand receptor 4 in human peripheral blood lymphocytes.

Yasuaki Yamada, S. Kamihira, H. Harasawa, 2004, Cellular immunology.

Quorum Sensing System Lactones Do Not Increase Invasiveness of a MexAB‐OprM Efflux Mutant but Do Play a Partial Role in Pseudomonas aeruginosa Invasion

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2006, Microbiology and immunology.

Overexpression of caveolin-1 in adult T-cell leukemia.

K. Ohshima, Yuetsu Tanaka, B. Burgering, 2010, Blood.

Legionella pneumophila induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2010, Respiratory research.

Two sporadic cases of infections due to Klebsiella pneumoniae resistant to expanded-spectrum cephalosporins in Japan

Yasuaki Yamada, S. Kamihira, Y. Ishii, 1999, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

Genetic Analysis of Serotype 23F Streptococcus pneumoniae Isolates from Several Countries by Penicillin-Binding Protein Gene Fingerprinting and Pulsed-Field Gel Electrophoresis

Yasuaki Yamada, S. Kamihira, M. Kaku, 1999, Chemotherapy.

Genetic Relationship between Blood and Nonblood Isolates from Bacteremic Patients Determined by Pulsed-Field Gel Electrophoresis

Yasuaki Yamada, S. Kamihira, S. Kohno, 1998, Journal of Clinical Microbiology.

Deoxycoformycin-Containing Combination Chemotherapy for Adult T-Cell Leukemia-Lymphoma: Japan Clinical Oncology Group Study (JCOG9109)

M. Tomonaga, Yasuaki Yamada, K. Tsukasaki, 2003, International journal of hematology.

Birth Cohort Effects on Incidence of Lung Cancers: A Population‐based Study in Nagasaki, Japan

Yasuaki Yamada, S. Kamihira, S. Kohno, 2000, Japanese journal of cancer research : Gann.

Osteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia

N. Maeda, Yasuaki Yamada, T. Ohashi, 2015, Retrovirology.

An Alternative Transcript Derived from the Trio Locus Encodes a Guanosine Nucleotide Exchange Factor with Mouse Cell-transforming Potential*

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2004, Journal of Biological Chemistry.

A Novel Alternative Splicing Isoform of Human T-Cell Leukemia Virus Type 1 bZIP Factor (HBZ-SI) Targets Distinct Subnuclear Localization

T. Koji, Yasuaki Yamada, S. Kamihira, 2006, Journal of Virology.

A novel role of serum cytochrome c as a tumor marker in patients with operable cancer

Yasuaki Yamada, S. Kamihira, M. Mine, 2009, Journal of Cancer Research and Clinical Oncology.

Adhesion-dependent growth of primary adult T cell leukemia cells with down-regulation of HTLV-I p40Tax protein: a novel in vitro model of the growth of acute ATL cells

H. Mano, M. Tomonaga, Yuetsu Tanaka, 2008, International journal of hematology.

Impact of visceral involvements and blood cell count abnormalities on survival in adult T-cell leukemia/lymphoma (ATLL).

M. Tomonaga, Yasuaki Yamada, Y. Takasaki, 2007, Leukemia research.

The possibility of a valuable resource of circulating DNA for single nucleotide polymorphisms genotyping: the application of a rapid and simple polymerase chain reaction with melting curve analysis for methyltetrahydrofolate reductase polymorphisms.

Yasuaki Yamada, S. Kamihira, K. Sugahara, 2007, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

Possible origin of adult T‐cell leukemia/lymphoma cells from human T lymphotropic virus type‐1‐infected regulatory T cells

M. Tomonaga, T. Matsuyama, T. Kohno, 2005, Cancer science.

Expression of CCR9 in HTLV‐1+ T cells and ATL cells expressing Tax

Yuetsu Tanaka, Yasuaki Yamada, K. Tsukasaki, 2007, International journal of cancer.

Impact of p53 aberration on the progression of Adult T-cell Leukemia/Lymphoma.

M. Tomonaga, Yasuaki Yamada, M. Tawara, 2006, Cancer letters.

The Current Status of Therapy for Adult T-cell Leukaemia-Lymphoma in Japan

M. Tomonaga, Yasuaki Yamada, 2003, Leukemia & lymphoma.

The conformational alteration of the mutated extracellular domain of Fas in an adult T cell leukemia cell line.

H. Isomoto, Yasuaki Yamada, M. Tawara, 2002, Biochemical and biophysical research communications.

Diversity of leukaemic cell morphology in ATL correlates with prognostic factors, aberrant immunophenotype and defective HTLV‐1 genotype

M. Tomonaga, Yasuaki Yamada, M. Tawara, 1999, British journal of haematology.

In vivo Retrovirus‐mediated Herpes Simplex Virus Thymidine Kinase Gene Therapy Approach for Adult T Cell Leukemia in a Rat Model

M. Tomonaga, Yuetsu Tanaka, M. Fujita, 1997, Japanese journal of cancer research : Gann.

Rat primary T cells expressing HTLV‐I tax gene transduced by a retroviral vector: In vitro and in vivo characterization

M. Tomonaga, M. Fujita, Yasuaki Yamada, 1996, International journal of cancer.

Molecular detection of pre‐atl state among healthy HTLV‐1 carriers in an endemic area of Japan

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1995, International journal of cancer.

Prognostic significance of the proportion of Ki‐67‐positive cells in adult t‐cell leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1991, Cancer.

Survey of Anti‐human T‐Cell Leukemia Virus Type I Antibody in Family Members of Patients with Adult T‐Cell Leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1990, Japanese journal of cancer research : Gann.

A lymphoproliferative disorder of Tγ cells with the phenotype of cytotoxic suppressor T‐cell

M. Tomonaga, Yasuaki Yamada, N. Sadamori, 1985 .

Preleukemic state of adult T cell leukemia: abnormal T lymphocytosis induced by human adult T cell leukemia-lymphoma virus

Yasuaki Yamada, S. Kamihira, M. Tagawa, 1985 .

Changes of adult T cell leukemia cell surface antigens at relapse or at exacerbation phase after chemotherapy defined by use of monoclonal antibodies

Yasuaki Yamada, S. Kamihira, S. Ikeda, 1984 .

Clinical, hematologic, and pathologic features of leukemic T‐cell lymphoma

Yasuaki Yamada, S. Kamihira, S. Ikeda, 1982, Cancer.

Adult T Cell Leukemia-Lymphoma in the Nagasaki District

Yasuaki Yamada, S. Kamihira, S. Ikeda, 1982 .

Risk of Adult T-cell Leukemia Developing Individuals with HTLV-I Infection

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1992 .

Dihydroflavonol BB-1, an extract of natural plant Blumea balsamifera, abrogates TRAIL resistance in leukemia cells.

Tatsushi Yoshida, T. Sakai, Yasuaki Yamada, 2006, Blood.

Human T-cell Leukemia Virus Type I Tax Protein Induces the Expression of Anti-Apoptotic Gene Bcl-xL in Human T-Cells through Nuclear Factor-κB and c-AMP Responsive Element Binding Protein Pathways

G. Cheng, M. Tomonaga, N. Mori, 2001, Virus Genes.

Clinical Relevance of Survivin as a Biomarker in Neoplasms, Especially in Adult T-Cell Leukemias and Acute Leukemias

H. Nagai, M. Tomonaga, Yasuaki Yamada, 2004, International journal of hematology.

Established IL‐2‐dependent double‐negative (CD4‐ CD8‐) TCRαβ/CD3+ ATL cells: induction of CD4 expression

M. Tomonaga, M. Fujita, Haruhiko Suzuki, 1994 .

Aberrant overexpression of membrane-associated mucin contributes to tumor progression in adult T-cell leukemia/lymphoma cells

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2011, Leukemia & lymphoma.

An ATL cell line with an IgH pseudo-rearranged band pattern by southern blotting: a pitfall of genetic diagnosis.

H. Nagai, Yasuaki Yamada, S. Kamihira, 2005, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

Involvement of p38 MAPK signaling pathway in IFN-γ and HTLV-I expression in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis

K. Eguchi, Yasuaki Yamada, S. Kohno, 2005, Journal of Neuroimmunology.

Elevated expression of CD30 in adult T-cell leukemia cell lines: possible role in constitutive NF-κB activation

N. Mori, Yasuaki Yamada, Toshiki Watanabe, 2005, Retrovirology.

Clinical and Oncologic Implications in Epigenetic Down-Regulation of CD26/ Dipeptidyl Peptidase IV in Adult T-Cell Leukemia Cells

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2004, International journal of hematology.

Expression of the c-Met proto-oncogene and its possible involvement in liver invasion in adult T-cell leukemia.

M. Tomonaga, Yuetsu Tanaka, T. Matsuyama, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Possible Attenuation of Fas-Mediated Signaling by Dominant Expression of Caspase-8 Aberrant Isoform in Adult T-cell Leukemia Cells

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2002, International journal of hematology.

Multiple γc‐receptor expression in adult T‐cell leukemia

M. Tomonaga, N. Mori, Yasuaki Yamada, 2002, European journal of haematology.

Circulating interleukin‐6 levels are elevated in adult T‐cell leukaemia/lymphoma patients and correlate with adverse clinical features and survival

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1998, British journal of haematology.

Soluble and membrane isoforms of Fas/CD95 in fresh adult T‐cell leukemia (ATL) cells and ATL‐cell lines

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1997, International journal of cancer.

A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 production.

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2007, Blood.

Elevated expression of CCL5/RANTES in adult T‐cell leukemia cells: Possible transactivation of the CCL5 gene by human T‐cell leukemia virus type I tax

K. Ohshima, A. Krensky, M. Tomonaga, 2004, International journal of cancer.

A T‐cell neoplasia showing clinicopathologic features of malignant histiocytosis with novel chromosomal abnormalities and N‐ras mutation

Yasuaki Yamada, M. Kikuchi, F. Takeshima, 1991, Cancer.

c‐Maf suppresses human T‐cell leukemia virus type 1 Tax by competing for CREB‐binding protein

Yuetsu Tanaka, Yasuaki Yamada, K. Tsukasaki, 2011, Cancer science.

Azithromycin inhibits nontypeable Haemophilus influenzae-induced MUC5AC expression and secretion via inhibition of activator protein-1 in human airway epithelial cells.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2010, European journal of pharmacology.

Foxp3 expression on normal and leukemic CD4+CD25+ T cells implicated in human T‐cell leukemia virus type‐1 is inconsistent with Treg cells

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2008, European journal of haematology.

Genetic diagnosis of community-acquired MRSA: a multiplex real-time PCR method for Staphylococcal cassette chromosome mec typing and detecting toxin genes.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2010, The Tohoku journal of experimental medicine.

Efficacy of linezolid against PVL-positive MRSA in a mouse model of hematogenous pulmonary infection

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2017 .

Efficacy of linezolid against Panton-Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) in a mouse model of haematogenous pulmonary infection.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2009, International journal of antimicrobial agents.

In Vitro Activity of Telithromycin (HMR3647), a New Ketolide, against Clinical Isolates of Mycoplasma pneumoniaein Japan

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2000, Antimicrobial Agents and Chemotherapy.

In vivo efficacy of sivelestat in combination with pazufloxacin against Legionella pneumonia

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2010, Experimental lung research.

EFFECTS OF SPECIFIC NEUTROPHIL ELASTASE INHIBITOR, SIVELESTAT SODIUM HYDRATE, IN MURINE MODEL OF SEVERE PNEUMOCOCCAL PNEUMONIA

Yasuaki Yamada, Y. Hirakata, K. Yanagihara, 2007, Experimental lung research.

Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2009, Pulmonary pharmacology & therapeutics.

Paradoxical expression of IL-28B mRNA in peripheral blood in human T-cell leukemia virus Type-1 mono-infection and co-infection with hepatitis C Virus

Yasuaki Yamada, S. Kamihira, K. Nagai, 2012, Virology Journal.

Title Azithromycin , clarithromycin and telithromycin inhibit MUC 5 ACinduction by Chlamydophila pneumoniae in airway epithelial cells

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2017 .

Downregulation of Bcl-xL and activation of caspases during retinoic acid-induced apoptosis in an adult T-cell leukemia cell line.

M. Kuroki, Yasuaki Yamada, J. Suzumiya, 2003, The hematology journal : the official journal of the European Haematology Association.

Aberrant processing of Fas transcripts in adult T-cell leukemia: a possible role in tumor cell survival.

M. Tomonaga, Yasuaki Yamada, M. Tawara, 2003, Cancer letters.

Adult T-cell leukemia with an unusual phenotype, Leu-2a positive and Leu-3a negative

Yasuaki Yamada, Y. Tomonaga, S. Ikeda, 1985, Blut.

A Novel Plasmacytoid Dendritic Cell Line, CAL-1, Established from a Patient with Blastic Natural Killer Cell Lymphoma

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2005, International journal of hematology.

Significance of soluble interleukin‐2 receptor levels for evaluation of the progression of adult T‐cell leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1994, Cancer.

Homozygous Deletions of the p 15 ( MTS 2 ) and p 16 ( CDKN 2 / MTS 1 ) Genes in Adult T-cell Leukemia

M. Tomonaga, H. Koeffler, Yasuaki Yamada, 2000 .

High-resolution melting analysis for a reliable and two-step scanning of mutations in the tyrosine kinase domain of the chimerical bcr-abl gene

Yasuaki Yamada, S. Kamihira, K. Nagai, 2009, International journal of hematology.

Multidrug resistance protein expression of adult T-cell leukemia/lymphoma.

Yasuaki Yamada, Yan-Hua Wang, M. Takanashi, 2007, Leukemia research.

A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period

K. Jeang, A. Nishizono, Yuetsu Tanaka, 2014, Retrovirology.

Advantage of higher-avidity CTL specific for Tax against human T-lymphotropic virus-1 infected cells and tumors.

Yuetsu Tanaka, N. Araya, Yasuaki Yamada, 2011, Cellular immunology.

Nationwide survey of adult T-cell leukemia/lymphoma (ATL) in Japan.

M. Satake, K. Yamaguchi, Yasuaki Yamada, 2011, [Rinsho ketsueki] The Japanese journal of clinical hematology.

Activation of cyclin D1 and D2 promoters by human T‐cell leukemia virus type I tax protein is associated with IL‐2–independent growth of T cells

F. Kashanchi, M. Tomonaga, Yuetsu Tanaka, 2002, International journal of cancer.

Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness.

M. Tomonaga, N. Mori, N. Yamamoto, 2002, Blood.

Clinical and oncological significance of aberrant Fas (APO-1/CD95) isoform expression in adult T-cell leukemia

Yasuaki Yamada, S. Kamihira, T. Maeda, 2000, Indian Journal of Clinical Biochemistry.

Quantitative characterization and potential function of membrane Fas/APO‐1 (CD95) receptors on leukaemic cells from chronic B and T lymphoid leukaemias

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1997, British journal of haematology.

Constitutive Activation of NFk B in Primary Adult T-Cell Leukemia Cells

M. Tomonaga, N. Mori, N. Yamamoto, 1999 .

Antibodies against p40tax Gene Product of Human T‐Lymphotropic Virus Type‐I (HTLV‐I) under Various Conditions of HTLV‐I Infection

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1989, Japanese journal of cancer research : Gann.

Antimicrobial Susceptibility Testing ofBilophila wadsworthia Isolates Submitted for Routine Laboratory Examination

Yasuaki Yamada, S. Kamihira, S. Kohno, 1998, Journal of Clinical Microbiology.

The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.

Yasuaki Yamada, S. Kamihira, M. Fukuda, 2004, Molecular cancer therapeutics.

The histone deacetylase inhibitor FR 901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells

Yasuaki Yamada, S. Kamihira, M. Fukuda, 2004 .

Adherence to and Penetration of Human Intestinal Caco-2 Epithelial Cell Monolayers by Pseudomonas aeruginosa

Yasuaki Yamada, S. Kamihira, S. Kohno, 1998, Infection and Immunity.

Immunoglobulin Classes of Antibody for Human T‐Lymphotropic Virus Type‐I (HTLV‐I) in Healthy Donors and HTLV‐I‐Associated Disorders

Yasuaki Yamada, M. Ichimaru, S. Momita, 1989, Vox sanguinis.

High Human T Cell Leukemia Virus Type-1(HTLV-1) Provirus Load in Patients with HTLV-1 Carriers Complicated with HTLV-1-unrelated disorders

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2010, Virology Journal.

Human T-Cell Leukemia Virus Type I Tax Activates Transcription of the Human Monocyte Chemoattractant Protein-1 Gene through Two Nuclear Factor-κB Sites

M. Tomonaga, N. Mori, N. Yamamoto, 2000 .

Human T-Cell Leukemia Virus Type I Tax Activates Transcription of the Human Monocyte Chemoattractant Protein-1 Gene through Two Nuclear Factor-k B Sites

M. Tomonaga, N. Mori, N. Yamamoto, 2000 .

Diagnostic Validity of Combining HTLV-1 Serology and Immunophenotyping in Adult T-Cell Leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1996 .

In vivo efficacy of doripenem (DRPM) against Pseudomonas aeruginosa in murine chronic respiratory tract infection model

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2011, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

In vivo efficacy and pharmacokinetics of tomopenem (CS-023), a novel carbapenem, against Pseudomonas aeruginosa in a murine chronic respiratory tract infection model.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2008, The Journal of antimicrobial chemotherapy.

Multiple immune abnormalities in a patient with idiopathic CD4+ T-lymphocytopenia.

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2009, Internal medicine.

A new G‐CSF‐supported combination chemotherapy, LSG15, for adult T‐cell leukaemia‐lymphoma: Japan Clinical Oncology Group Study 9303

M. Tomonaga, S. Hanada, A. Utsunomiya, 2001, British journal of haematology.

Aberrant p53 protein expression and function in a panel of hematopoietic cell lines with different p53 mutations

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2009, European journal of haematology.

Rapid and accurate detection of Pseudomonas aeruginosa by real-time polymerase chain reaction with melting curve analysis targeting gyrB gene.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2007, Diagnostic microbiology and infectious disease.

Usefulness of a comprehensive PCR-based assay for human herpes viral DNA in blood mononuclear cell samples.

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2005, Laboratory hematology : official publication of the International Society for Laboratory Hematology.

Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia.

K. Yamaguchi, K. Uozumi, A. Utsunomiya, 2005, Blood.

Interruption of p16 gene expression in adult T‐cell leukaemia/lymphoma: clinical correlation

M. Tomonaga, Yasuaki Yamada, Y. Takasaki, 2003, British journal of haematology.

Analysis of p18INK4C in adult T‐cell leukaemia and non‐Hodgkin's lymphoma

K. Spirin, Yasuaki Yamada, J. Said, 1997, British journal of haematology.

Immunological Aspects of Adult T-Cell Leukemia/Lymphoma (ATLL), a Possible Neoplasm of Regulatory T-Cells

Yasuaki Yamada, S. Kamihira, 2008 .

Lactacystin activates FLICE (caspase 8) protease and induces apoptosis in Fas‐ resistant adult T‐cell leukemia cell lines

M. Tomonaga, N. Mori, Yasuaki Yamada, 2000, European journal of haematology.

The State of the Art in the Pathogenesis of ATL and New Potential Targets Associated with HTLV-1 and ATL

Yasuaki Yamada, K. Murata, 2007, International reviews of immunology.

Serum Levels of Soluble Fas/APO-1 Receptor in HumanRetroviral Infection and Associated Diseases human retroviral infection and

Youichi, M. Tomonaga, Takahiro, 2007 .

Aberrant expression of caspase cascade regulatory genes in adult T‐cell leukaemia: survivin is an important determinant for prognosis

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 2001, British journal of haematology.

Soluble Fas (APO-1/CD95) Isoform in Adult T-Cell Leukemia

Yasuaki Yamada, S. Kamihira, Y. Yamada, 2001, Leukemia & lymphoma.

Discrepant expression of membrane and soluble isoforms of Fas (CD95/APO‐1) in adult T‐cell leukaemia: soluble Fas isoform is an independent risk factor for prognosis

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1999, British journal of haematology.

Fas Gene Mutation in the Progression of Adult T Cell Leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1999, The Journal of experimental medicine.

Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells.

M. Tomonaga, Yuetsu Tanaka, N. Mori, 2002, Blood.

Usefulness of Long Distance Inverse Polymerase Chain Reaction for the molecular detection of the 14 q 32 translocation in clinical setting

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2017 .

Usefulness of long‐distance inverse polymerase chain reaction for molecular detection of 14q32 translocation in a clinical setting

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2008, Scandinavian journal of clinical and laboratory investigation.

Expression of CD8β and alteration of cell surface phenotype in adult T‐cell leukaemia cells

M. Seto, M. Tomonaga, Yasuaki Yamada, 1997, British journal of haematology.

Expression and functional analyses of breast cancer resistance protein in lung cancer.

Yasuaki Yamada, S. Kamihira, K. Sugahara, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Characteristic expression of HTLV-1 basic zipper factor (HBZ) transcripts in HTLV-1 provirus-positive cells

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2008, Retrovirology.

Adult T cell leukaemia cells are of CD4+ CDw29+ T cell origin and secrete a B cell differentiation factor

Yasuaki Yamada, H. Shiku, Y. Yamada, 1989, British journal of haematology.

Matrix metalloproteinase‐9 and vascular endothelial growth factor: a possible link in adult T‐cell leukaemia cell invasion

M. Tomonaga, N. Mori, Yasuaki Yamada, 2002, British journal of haematology.

Successful Treatment With a Chimeric Anti-CD20 Monoclonal Antibody (IDEC-C2B8, Rituximab) for a Patient With Relapsed Mantle Cell Lymphoma Who Developed a Human Anti-Chimeric Antibody

M. Tomonaga, Yasuaki Yamada, M. Tawara, 2001, International journal of hematology.

Adult T‐cell leukemia cells over‐express the multidrug‐resistance‐protein (MRP) and lung‐resistance‐protein (LRP) genes

M. Tomonaga, H. Isomoto, Yasuaki Yamada, 1999, International journal of cancer.

Histone deacetylase inhibitors suppress telomerase reverse transcriptase mRNA expression in prostate cancer cells.

C. Tei, Yasuaki Yamada, S. Kamihira, 2002, International journal of cancer.

Overexpression of enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy

H. Mano, Yasuaki Yamada, S. Kamihira, 2011, Haematologica.

Survey of chemokine receptor expression reveals frequent co-expression of skin-homing CCR4 and CCR10 in adult T-cell leukemia/lymphoma

M. Tomonaga, Yasuaki Yamada, Y. Takasaki, 2006, Leukemia & lymphoma.

Primary T-cell lymphoma of the thyroid gland with chemokine receptors of Th1 phenotype complicating autoimmune thyroiditis.

K. Ohshima, M. Tomonaga, Yasuaki Yamada, 2007, Haematologica.

Long-term study of indolent adult T-cell leukemia-lymphoma.

M. Tomonaga, T. Kohno, Yasuaki Yamada, 2007, Blood.

Identification of Genes Associated with the Progression of Adult T Cell Leukemia (ATL)

Masao Tomonaga, M. Tomonaga, T. Matsuyama, 2000, Japanese journal of cancer research : Gann.

DISAPPEARANCE OF CD4 ANTIGEN IN A CASE OF ADULT T CELL LEUKAEMIA

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1992, British journal of haematology.

Apoptosis Induced by the Histone Deacetylase Inhibitor FR901228 in Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines and Primary Adult T-Cell Leukemia Cells

M. Tomonaga, Yuetsu Tanaka, N. Mori, 2004, Journal of Virology.

Leukemia Cells T-Cell Lines and Primary Adult T-Cell T-Cell Leukemia Virus Type 1-Infected Deacetylase Inhibitor FR 901228 in Human Apoptosis Induced by the Histone

M. Tomonaga, Yuetsu Tanaka, N. Mori, 2004 .

Possible association between adult T‐cell leukemia/Lymphoma and acute myeloid leukemia

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1998, Cancer.

Possible Involvement of Interferon Regulatory Factor 4 (IRF4) in a Clinical Subtype of Adult T‐Cell Leukemia

M. Tomonaga, Yuetsu Tanaka, T. Matsuyama, 2001, Japanese journal of cancer research : Gann.

Rapid isolation of viral integration site reveals frequent integration of HTLV-1 into expressed loci

M. Isobe, M. Tomonaga, Yasuaki Yamada, 2004, Journal of Human Genetics.

Interleukin-15 (IL-15) Can Replace the IL-2 Signal in IL-2–Dependent Adult T-Cell Leukemia (ATL) Cell Lines: Expression of IL-15 Receptor α on ATL Cells

M. Tomonaga, T. Kohno, Yasuaki Yamada, 1998 .

Infective dermatitis among patients with ATL in Japan

M. Tomonaga, Yasuaki Yamada, K. Tsukasaki, 1994, International journal of cancer.

Chromosomal imbalances in adult T-cell leukemia revealed by comparative genomic hybridization: gains at 14q32 and 2p16-22 in cell lines

Yusuke Nakamura, M. Isobe, M. Seto, 1999, Journal of Human Genetics.

A Relevant Reference Gene and Normalization for mRNA Real-Time PCR Quantification in Specimens with Distinct Cell Types and Variant Integrity

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2006 .

Microsatellite instability in adult T‐cell leukaemia

M. Tomonaga, H. Koeffler, Yasuaki Yamada, 1998, British journal of haematology.

Rapid, Simple, and Accurate Detection of K-ras Mutations From Body Fluids Using Real-Time PCR and DNA Melting Curve Analysis

Yasuaki Yamada, S. Kamihira, T. Kuroki, 2006 .

High IL-21 receptor expression and apoptosis induction by IL-21 in follicular lymphoma.

K. Makabe, I. Kumagai, Yasuaki Yamada, 2007, Cancer letters.

Activated t‐lymphocytes with polyclonal gammopathy in patients with human t‐lymphotropic virus type i—associated myelopathy

Yasuaki Yamada, H. Shiku, N. Ban, 1988, Annals of neurology.

A subtype of aggressive B-cell lymphoma with an unusual presentation of effusion without masses

Yasuaki Yamada, S. Kamihira, K. Sugahara, 2006, Leukemia & lymphoma.

Trends in HTLV‐1 prevalence and incidence of adult T‐cell leukemia/lymphoma in Nagasaki, Japan

K. Yamaguchi, Yasuaki Yamada, S. Kamihira, 2010, Journal of medical virology.

Elevation of serum KL-6 glycoprotein or surfactant protein-D in adult T-cell leukemia with distinct pulmonary complications.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2009, Tohoku journal of experimental medicine.

The incidence of adult T-cell leukemia/lymphoma among human T-lymphotropic virus type 1 carriers in Japan

M. Satake, K. Yamaguchi, Yasuaki Yamada, 2015, Leukemia & lymphoma.

- 1-Efficacy of ME 1036 against methicillin-resistant Staphylococcus aureus and vancomycin-insensitive S . aureus in a model of hematogenous pulmonary infection

Shintaro, Kurihara, Yasuaki Yamada, 2017 .

Efficacy of ME1036 against meticillin-resistant Staphylococcus aureus and vancomycin-insensitive S. aureus in a model of haematogenous pulmonary infection.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2008, International journal of antimicrobial agents.

CXCR7 is inducible by HTLV‐1 Tax and promotes growth and survival of HTLV‐1‐infected T cells

Yasuaki Yamada, O. Yoshie, K. Hieshima, 2009, International journal of cancer.

Relationship between whole-blood interferon-gamma production and extent of radiographic disease in patients with pulmonary tuberculosis.

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2003, Diagnostic microbiology and infectious disease.

Detection of adult T‐Cell leukemia‐associated antigen in T‐Cell malignancies in the Nagasaki district of Japan

Yasuaki Yamada, Y. Yamada, S. Ikeda, 1984, Cancer.

Acute myeloid leukaemia with t(9;11)(p22;q23) in a patient treated for adult T cell leukaemia

M. Tomonaga, Y. Yoshida, Yasuaki Yamada, 1994, British journal of haematology.

Paradoxical expression of IL-28B mRNA in peripheral blood in human T-cell leukemia virus Type-1 mono-infection and co-infection with hepatitis C Virus

Yasuaki Yamada, S. Kamihira, K. Nagai, 2012, Virology Journal.

HIV- and HHV-8-negative Primary Effusion Lymphoma Harboring the Dual Rearrangement of Antigen Receptor Genes and a Translocation of bcl-6

Yasuaki Yamada, S. Kamihira, Y. Hirakata, 2006 .

Automation of bone marrow aspirate examination using the XE‐2100 automated hematology analyzer

Yukio Hamaguchi, Yasuaki Yamada, S. Kamihira, 2004, Cytometry. Part B, Clinical cytometry.

Extensive analysis of the retinoblastoma gene in adult T cell leukemia/lymphoma (ATL)

M. Tomonaga, H. Koeffler, Yasuaki Yamada, 1997, Leukemia.

Constitutive activation of transcription factor AP-1 in primary adult T-cell leukemia cells.

M. Tomonaga, Yuetsu Tanaka, N. Mori, 2000, Blood.

Detailed deletion mapping of the long arm of chromosome 6 in adult T-cell leukemia.

M. Tomonaga, H. Koeffler, Yasuaki Yamada, 1999, Blood.

Frequent Clonal Change at Crisis From Indolent Disease Integration Patterns of HTLV-I Provirus in Relation to the Clinical Course of

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1997 .

Vascular endothelial growth factor and cellular chemotaxis: a possible autocrine pathway in adult T-cell leukemia cell invasion.

M. Tomonaga, N. Mori, Yasuaki Yamada, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Expression of human inducible nitric oxide synthase gene in T-cell lines infected with human T-cell leukemia virus type-I and primary adult T-cell leukemia cells.

M. Tomonaga, N. Mori, N. Yamamoto, 1999, Blood.

Pathological roles of interleukin-15 in adult T-cell leukemia.

Yasuaki Yamada, S. Kamihira, Y. Yamada, 1999, Leukemia & lymphoma.

Features of the cytokines secreted by adult T cell leukemia (ATL) cells.

M. Tomonaga, T. Kohno, Yasuaki Yamada, 1996, Leukemia & lymphoma.

Breast cancer resistance protein directly confers SN-38 resistance of lung cancer cells.

L. Doyle, D. Ross, Yasuaki Yamada, 2001, Biochemical and biophysical research communications.

Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL)

M. Tomonaga, H. Sasaki, Yasuaki Yamada, 2002, Leukemia.

Expression of human inducible nitric oxide synthase gene in T-cell lines infected with human T-cell leukemia virus type-I and primary adult T-cell leukemia cells.

M. Tomonaga, N. Mori, N. Yamamoto, 1999, Blood.

Effect of Pseudomonas aeruginosa exotoxin A on endotoxin-induced tumour necrosis factor production in murine lung.

T. Kirikae, Yasuaki Yamada, S. Kamihira, 1999, Journal of medical microbiology.

Legionella pneumophila induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2010, Respiratory research.

Serum levels of soluble Fas/APO-1 receptor in human retroviral infection and associated diseases.

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1997, Internal medicine.

Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2009, Leukemia.

Apoptosis Induced by the Histone Deacetylase Inhibitor FR901228 in Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines and Primary Adult T-Cell Leukemia Cells

M. Tomonaga, Yuetsu Tanaka, N. Mori, 2004, Journal of Virology.

Poor outcome of autologous stem cell transplantation for adult T cell leukemia/lymphoma: a case report and review of the literature

M. Tomonaga, Yasuaki Yamada, K. Tsukasaki, 1999, Bone Marrow Transplantation.

A genomic analysis of adult T-cell leukemia

H. Aburatani, T. Nakamura, M. O'Neill, 2007, Oncogene.

Aberrant overexpression of membrane-associated mucin contributes to tumor progression in adult T-cell leukemia/lymphoma cells

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2011, Leukemia & lymphoma.

High-resolution melting analysis for a reliable and two-step scanning of mutations in the tyrosine kinase domain of the chimerical bcr-abl gene

Yasuaki Yamada, S. Kamihira, K. Nagai, 2009, International journal of hematology.

LBH589, a deacetylase inhibitor, induces apoptosis in adult T-cell leukemia/lymphoma cells via activation of a novel RAIDD-caspase-2 pathway

N. Mori, Yasuaki Yamada, S. Kamihira, 2011, Leukemia.

Interleukin-15 (IL-15) can replace the IL-2 signal in IL-2-dependent adult T-cell leukemia (ATL) cell lines: expression of IL-15 receptor alpha on ATL cells.

M. Tomonaga, T. Kohno, Yasuaki Yamada, 1998, Blood.

Detection of methylthioadenosine phosphorylase (MTAP) and p16 gene deletion in T cell acute lymphoblastic leukemia by real-time quantitative PCR assay

A. Yu, Yasuaki Yamada, J. Nishioka, 2000, Leukemia.

A novel role of serum cytochrome c as a tumor marker in patients with operable cancer

Yasuaki Yamada, S. Kamihira, M. Mine, 2009, Journal of Cancer Research and Clinical Oncology.

Frequent hepatic involvement in adult T cell leukemia: comparison with non-Hodgkin's lymphoma.

M. Tomonaga, Yasuaki Yamada, S. Kamihira, 1997, Leukemia & lymphoma.

Subinhibitory concentrations of telithromycin, clarithromycin and azithromycin reduce methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo.

Yasuaki Yamada, S. Kamihira, K. Yanagihara, 2008, The Journal of antimicrobial chemotherapy.

Rapid and high‐resolution detection of IgH gene rearrangements using PCR and melting curve analysis

Yasuaki Yamada, S. Kamihira, K. Tsukasaki, 2007, International journal of laboratory hematology.