P. Cappella

发表

Multiparametric Cell Cycle Analysis by Automated Microscopy

Paolo Cappella, F. Gasparri, A. Galvani, 2006, Journal of biomolecular screening.

A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds

F. Gasparri, P. Cappella, Mario Mauri, 2015, PloS one.

In vivo imaging of early stage apoptosis by measuring real-time caspase-3/7 activation

P. Cappella, E. Pesenti, F. Stellari, 2011, Apoptosis.

PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer

Paola Storici, Cristina Alli, Maurizio Rocchetti, 2007, Molecular Cancer Therapeutics.

PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity

D. Ballinari, V. Croci, P. Cappella, 2006, Clinical Cancer Research.

Application of Click Chemistry Conditions for 5‐Bromo‐2′‐Deoxyuridine Determination Through Fenton and Related Reactions

F. Gasparri, P. Cappella, M. Pulici, 2015, Current protocols in cytometry.

Assessment of Cell Cycle Inhibitors by Flow Cytometry

P. Cappella, J. Moll, 2011 .

Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo.

P. Cappella, F. Sola, R. Alzani, 2010, Anticancer research.

Characterization of cyclin B1 expression in human cancer cell lines by a new three-parameter BrdUrd/cyclin B1/DNA analysis.

M. Faretta, P. Ubezio, E. Erba, 1998, Cytometry.

Miniaturizing bromodeoxyuridine incorporation enables the usage of flow cytometry for cell cycle analysis of adherent tissue culture cells for high throughput screening

P. Ubezio, M. Ciomei, P. Cappella, 2010, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors.

D. Ballinari, V. Croci, D. Volpi, 2010, Journal of medicinal chemistry.

1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.

Paola Storici, Maurizio Rocchetti, Enrico Pesenti, 2006, Journal of medicinal chemistry.

Potent and selective Aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition.

A. Vulpetti, F. Roletto, P. Cappella, 2005, Journal of medicinal chemistry.

CyTOF Mass Cytometry for Click Proliferation Assays

P. Cappella, V. Tosevski, E. Ulashchik, 2017, Current protocols in cytometry.

Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity.

V. Croci, D. Volpi, F. Roletto, 2010, Bioorganic & medicinal chemistry.

Synthesis of novel, simplified, C-7 substituted eleutheside analogues with potent microtubule-stabilizing activity

P. Cappella, Lorenzo Caggiano, Anna M. Costa, 2005 .

Interpreting cell cycle effects of drugs: the case of melphalan

Paolo Ubezio, Monica Lupi, Paolo Cappella, 2006, Cancer Chemotherapy and Pharmacology.

A novel method based on click chemistry, which overcomes limitations of cell cycle analysis by classical determination of BrdU incorporation, allowing multiplex antibody staining

F. Gasparri, P. Cappella, M. Pulici, 2008, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase.

Antonella Isacchi, Riccardo Colombo, Enrico Pesenti, 2010, Cancer research.

Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells.

R. Bosotti, A. Isacchi, P. Cappella, 2012, Gene.

NMS-P937, an Orally Available, Specific Small-Molecule Polo-like Kinase 1 Inhibitor with Antitumor Activity in Solid and Hematologic Malignancies

A. Isacchi, E. Felder, D. Ballinari, 2012, Molecular Cancer Therapeutics.

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients

E. Sartori, S. Calza, M. D’Incalci, 2017, Journal of Experimental & Clinical Cancer Research.

5-(2-amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors.

D. Ballinari, F. Fiorentini, M. Brasca, 2012, Bioorganic & medicinal chemistry letters.

Preclinical Development NMSP 937 , an Orally Available , Speci fi c Small-Molecule Polo-like Kinase 1 Inhibitor with Antitumor Activity in Solid and Hematologic Malignancies

A. Isacchi, E. Felder, D. Ballinari, 2012 .

GDF15 as a Novel Biomarker for Monitoring Danusertib Activity

P. Cappella, P. Carpinelli, 2012 .

Measuring the complexity of cell cycle arrest and killing of drugs: kinetics of phase-specific effects induced by taxol.

P Ubezio, P. Ubezio, P. Cappella, 1999, Cytometry.

Cell Proliferation Method: Click Chemistry Based on BrdU Coupling for Multiplex Antibody Staining

F. Gasparri, P. Cappella, M. Pulici, 2008, Current protocols in cytometry.

From “Click” to “Fenton” chemistry for 5‐bromo‐2′‐deoxyuridine determination

Paolo Cappella, F. Gasparri, P. Cappella, 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Cell cycle effects of gemcitabine

P Ubezio, M D'Incalci, M. Faretta, 2001, International journal of cancer.

Identification of Myb-binding Protein 1A (MYBBP1A) as a Novel Substrate for Aurora B Kinase

M. Modugno, A. Isacchi, P. Cappella, 2010, The Journal of Biological Chemistry.

Neuroinflammation, body temperature and behavioural changes in CD1 male mice undergoing acute restraint stress: An exploratory study

J. Roughan, G. Parati, V. Redaelli, 2021, PloS one.

Highly Multiplexed Phenotypic Imaging for Cell Proliferation Studies

Paolo Cappella, F. Gasparri, P. Cappella, 2014, Journal of biomolecular screening.

Quantitative assessment of the complex dynamics of G1, S, and G2-M checkpoint activities.

Paolo Ubezio, Monica Lupi, Valentina Colombo, 2009, Cancer research.