Ming-Jung Wu

发表

Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDA, in chronic myeloid leukemia (K562) cells

Sheng-Huei Yang, C. Chien, Shinne‐ren Lin, 2006, Molecular and Cellular Biochemistry.

Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists.

G. Hynd, D. Selley, Ming-Jung Wu, 2005, Bioorganic & medicinal chemistry.

Design, Synthesis and Biological Evaluations of a Novel Series of Enediynes Constituted with DNA Cleavage, Alkylating and DNA Binding Agents via Varies Spacers

Ming-Jung Wu, Y. Kuo, Chi-Fong Lin, 2007 .

Thermolysis of 2-(3-phenylsulfonylprop-1-ynyl)benzonitrile: an aza-Myers type cyclization to isoquinolines

Ming-Jung Wu, Chi-Fong Lin, Shangdong Chen, 1999 .

Synthesis and Biological Activities of Aryl Propargyl Sulfone

Ming-Jung Wu, Tsai-Hui Duh, Chi-Fong Lin, 1998 .

Allene-Eneyne Related Cycloaromatization: Design and Synthesis of New DNA-Cleaving Compounds

Ming-Jung Wu, Tsai-Hui Duh, Chi-Fong Lin, 1998 .

MOLECULAR DESIGN, CHEMICAL SYNTHESIS AND BIOLOGICAL STUDIES OF NOVEL ENEDIYNES RELATED TO DYNEMICIN A

Ming-Jung Wu, S. Hsu, Tsai-Hui Duh, 1996 .

Chemical synthesis, DNA cleavage and antitumor activity of molecules with (Z)-7-sulfonyl-3-hexene-1,5-diyne functionalities

Ming-Jung Wu, C. Ong, Chi-Fong Lin, 1996 .

A direct anionic cyclization of 2-alkynylbenzonitrile to 3-substituted-1(2H)-isoquinolones and 3-benzylideneisoindol-2-ones initiated by methoxide addition

Ming-Jung Wu, Chi-Fong Lin, Li‐Juan Chang, 1999 .

Substituent Effect on Anionic Cycloaromatization of 2‐(2‐Substituted ethynyl)benzonitriles and Related Molecules.

Ming-Jung Wu, Chi-Fong Lin, Wen-Der Lu, 2003 .

3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor.

Ming-Jung Wu, B. Martin, J. Wiley, 2003, Bioorganic & medicinal chemistry.

Design, synthesis, biological evaluation and molecular modeling studies of 1-aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)-hexen-1,5-diynes as a new class of potent antitumor agents.

Ying-Ting Lin, P. Lu, Ming-Jung Wu, 2013, European journal of medicinal chemistry.

Induction of G2/M phase arrest and apoptosis by a novel enediyne derivative, THDB, in chronic myeloid leukemia (HL-60) cells.

Sheng-Huei Yang, C. Chien, Shinne‐ren Lin, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Synthesis of benzofulvenes by palladium-catalyzed cyclization of 1,2 -dialkynylbenzenes

Ming-Jung Wu, Chia-Ying Lee, 2007 .

Solvent Effects on Aza‐anionic Cycloaromatization of 2‐(2‐Substituted‐ethynyl)benzonitriles

Ming-Jung Wu, P. Hsieh, Chi-Fong Lin, 2001 .

Synthesis of (.+-.)-11-nor-9-carboxy-.DELTA.9-tetrahydrocannabinol. New synthetic approaches to cannabinoids

Ming-Jung Wu, Xuehai Zhang, J. Huffman, 1991 .

Nucleophilic ring opening of tetrahydro-1,3-oxazines and 1,3-oxazolidines by alkynyl anions : a novel synthesis of β-aminoacetylenes

Ming-Jung Wu, Shu‐Hui Chen, Der-Shenq Yan, 1994 .

A Very Facile SNAr Reaction with Elimination of Methoxide

Ming-Jung Wu, J. Huffman, Jianzhong Lu, 1998 .

New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata.

C. Liaw, Y. Wu, F. Chang, 2002, Journal of natural products.

Halocyclization of Methyl 2‐Alkynylbenzoates to Isocoumarins Using Cupric Halides

Ming-Jung Wu, Yu-Hsiang Lo, Chia-Ying Lee, 2008 .

Substituent effect on anionic cycloaromatization of 2-(2-substituted ethynyl)benzonitriles and related molecules

Ming-Jung Wu, Chi-Fong Lin, Wen-Der Lu, 2002 .

Palladium‐Catalyzed Cyclization of Enediynes to Benzopyranones

Ming-Jung Wu, Weichieh Chang, Yu-Hsiang Lo, 2008 .

Synthesis and antitumor activity of cis-dichloroplatinum(II) complexes of 1-(2-aminophenyl)-1,2,3,4-tetrahydroisoquinolines.

Ming-Jung Wu, Y. Kuo, Chen-Yuan Kuo, 2006, European journal of medicinal chemistry.

Palladium-catalyzed reactions of aryl iodides with trimethylsilylacetylenes and disubstituted alkynes: the synthesis of diarylacetylenes and triarylethylenes

Ming-Jung Wu, Chi-Fong Lin, Li-Mei Wei, 2001 .

Synthesis of carbazoles via an intramolecular cyclization of 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines and their related molecules.

Ming-Jung Wu, C. Chiu, Chi-Fong Lin, 2004, The Journal of organic chemistry.

Palladium-catalyzed coupling of aryl iodides with 2-alkynylbenzonitriles

Ming-Jung Wu, Chi-Fong Lin, Li-Mei Wei, 2000 .

Synthesis of 3-Halogenated Flavonoids via Electrophile-Promoted Cyclization of 2-(3-Aryl-2-propynoyl)anisoles

Ming-Jung Wu, Tsai-Hui Duh, Chi-Fong Lin, 2004 .

Synthesis of (15S,16S,21R)-4-deoxyrollicosin analog

Ming-Jung Wu, Yang-chang Wu, Jeng-Lin Lee, 2003 .

Bullatacin, a potent antitumor Annonaceous acetogenin, induces apoptosis through a reduction of intracellular cAMP and cGMP levels in human hepatoma 2.2.15 cells.

Ming-Jung Wu, H. Chiu, C. Tseng, 2003, Biochemical pharmacology.

Substituent effects on the cyclization mode of 7-sulfonyl-3-hepten-1,5-diynes and 11-sulfonylundeca-3,7-dien-1,5,9-triynes

Ming-Jung Wu, Chi-Fong Lin, Wen-Der Lu, 2004 .

Anionic cycloaromatization of 1-aryl-3-hexen-1,5-diynes initiated by methoxide addition: synthesis of phenanthridinones, benzo[c]phenanthridinones, and biaryls.

Ming-Jung Wu, Chi-Fong Lin, Wen-Der Lu, 2002, The Journal of organic chemistry.

Cytotoxicities, cell cycle and caspase evaluations of 1,6-diaryl-3(Z)-hexen-1,5-diynes, 2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines and their derivatives.

Ming-Jung Wu, Jeh-Jeng Wang, Ming-Chu Hsieh, 2005, Bioorganic & medicinal chemistry.

A novel constituent from Rollinia mucosa, rollicosin, and a new approach to develop annonaceous acetogenins as potential antitumor agents.

C. Liaw, Y. Wu, F. Chang, 2003, Journal of natural products.

Bioactive acetogenins from the seeds of Annona atemoya

F. Chang, Ming-Jung Wu, H. Chiu, 1999 .

Synthesis of 1,5-diphenylpent-3-en-1-yne derivatives utilizing an aqueous B-alkyl Suzuki cross coupling reaction

Y. Wu, F. Chang, Ming-Jung Wu, 2013 .

Design, syntheses, and biological evaluations of squamostolide and its related analogs.

Shinne‐ren Lin, Ming-Jung Wu, Chi-Fong Lin, 2005, Bioorganic & medicinal chemistry.

Synthesis of (4R,15R,16R,21S)-Rollicosin and Its 4S Epimer

Ming-Jung Wu, Yang-chang Wu, C. Lee, 2008 .

New cytotoxic withanolides from Physalis peruviana

Chin‐Chung Wu, Y. Wu, F. Chang, 2009 .

JNK and ERK mitogen-activated protein kinases mediate THDA-induced apoptosis in K562 cells

C. Chien, Long-Sen Chang, Shinne‐ren Lin, 2008, Cell Biology and Toxicology.

Synthesis of 5′,11-dihydroxy-Δ8-tetrahydrocannabinol

Ming-Jung Wu, J. Huffman, D. Dai, 1997 .

Synthesis of (.+‐.)‐11‐Nor‐9‐carboxy‐δ9‐tetrahydrocannabinol: New Synthetic Approaches to Cannabinoids.

Ming-Jung Wu, J. Huffman, W. Pennington, 2010 .

Design and Synthesis of 1-(6-(2-(2-Arylethynyl)phenyl)hexyn-5-yl)piperidin-2-ones as Antitumor Agents that Induce Apoptotic Progress

Shinne‐ren Lin, Ming-Jung Wu, I-Hsiang Chen, 2008 .

Novel acyclic enediynes inhibit Cyclin A and Cdc25C expression and induce apoptosis phenomenon to show potent antitumor proliferation.

Shinne‐ren Lin, Ming-Jung Wu, I.-L. Lin, 2007, Bioorganic & medicinal chemistry.

Remarkable G2/M phase arrest and apoptotic effect performed by 2-(6-aryl-3-hexen-1,5-diynyl) benzonitrile antitumor agents.

Ming-Jung Wu, Ming-Chu Hsieh, Yu-Hsiang Lo, 2004, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel symmetry bis-enediynes.

Shinne‐ren Lin, Ming-Jung Wu, Li-Yi Chen, 2009, European journal of medicinal chemistry.

Synthesis, Double Cycloaromatization, and DNA-Cleaving Activities of (Z,Z)-11-Sulfonylundeca-3,7-diene-1,5,9-triyne System

Ming-Jung Wu, Chi-Fong Lin, 1997 .

Halocyclization of 2-Alkynylthioanisoles by Cupric Halides: Synthesis of 2-Substituted 3-Halobenzo[b]thiophenes.

Ming-Jung Wu, Wen-Der Lu, 2007 .

Catalytic activity-independent pathway is involved in phospholipase A(2)-induced apoptotic death of human leukemia U937 cells via Ca(2+)-mediated p38 MAPK activation and mitochondrial depolarization.

Shinne‐ren Lin, Ming-Jung Wu, Yi-Ling Chiou, 2009, Toxicology letters.

2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines as a new class of potent antitubulin agents.

Ying-Ting Lin, Ching-Chih Lin, Yi-Ren Hong, 2008, Journal of medicinal chemistry.

Membrane-bound conformation of Naja nigricollis toxin gamma affects its membrane-damaging activity.

Ming-Jung Wu, Pei-Hsiu Kao, L. Chang, 2009, Toxicon : official journal of the International Society on Toxinology.

Membrane-bound conformation and phospholipid components modulate membrane-damaging activity of Taiwan cobra cardiotoxins.

Shinne‐ren Lin, Ming-Jung Wu, Pei-Hsiu Kao, 2009, Toxicon : official journal of the International Society on Toxinology.

A route to 5-substituted dibenzofurans by anionic cycloaromatization of 2-(6-substituted 3-hexen-1,5-diynyl)phenyl tert-butyldimethyl ethers and related molecules.

Ming-Jung Wu, Chi-Fong Lin, Chia-Ying Lee, 2002, Angewandte Chemie.

Regioselective synthesis of (.+-.)-11-Nor-9-carboxy-.DELTA.9-THC

Ming-Jung Wu, Xuehai Zhang, J. Huffman, 1989 .

Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding.

Ming-Jung Wu, G. Griffin, B. Martin, 2000, Drug and alcohol dependence.