Soohyun Kim

Soohyun Kim, Jaewoo Hong, P. Lin, 2019, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.

M. Netea, S. Girardin, E. Abraham, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Generation of monoclonal antibodies against recombinant AtSIZ1.

Soohyun Kim, Jaewoo Hong, Suyoung Bae, 2010, Hybridoma.

THP-1 Human Macrophages in Differentiated Mycobacterium tuberculosis IL-32 Is a Host Protective Cytokine against

E. Chan, C. Dinarello, Soohyun Kim, 2010 .

IL-32 Is a Host Protective Cytokine against Mycobacterium tuberculosis in Differentiated THP-1 Human Macrophages

Hua Huang, E. Chan, C. Dinarello, 2010, The Journal of Immunology.

Mutation Scan of a Type 1 Diabetes Candidate Gene

F. Pociot, C. Dinarello, Soohyun Kim, 2003, Annals of the New York Academy of Sciences.

Role of Dendritic Cell in Diabetic Nephropathy

Soohyun Kim, H. Lee, H. Jhun, 2021, International journal of molecular sciences.

Jeon, J. H. et al. A novel adipokine CTRP1 stimulates aldosterone production. FASEB J. 22, 1502-1511

Young Yang, Kun-Yong Kim, D. Yoon, 2008 .

A novel adipokine CTRP1 stimulates aldosterone production

Young Yang, Kun-Yong Kim, D. Yoon, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The Interleukin-1α Precursor is Biologically Active and is Likely a Key Alarmin in the IL-1 Family of Cytokines

C. Dinarello, Soohyun Kim, Eunsom Kim, 2013, Front. Immunol..

Characteristics of asthmatics with detectable IL-32γ in induced sputum.

Choon-Sik Park, Soohyun Kim, K. Min, 2017, Respiratory medicine.

Up-regulation of reactive oxygen species (ROS) and resistance to Fas-mediated apoptosis in the C33A cervical cancer cell line transfected with IL-18 receptor

D. Yoon, Soohyun Kim, Y. Cho, 2004, Clinical chemistry and laboratory medicine.

Increased Cytokine Production in Interleukin-18 Receptor α-deficient Cells Is Associated with Dysregulation of Suppressors of Cytokine Signaling*

C. Dinarello, Soohyun Kim, M. Nold, 2009, The Journal of Biological Chemistry.

Generation and characterization of mice transgenic for human IL‐18‐binding protein isoform a

Andrea Vondracek, G. Fantuzzi, C. Dinarello, 2003, Journal of leukocyte biology.

A simple method to screen ligands of peroxisome proliferator-activated receptor delta.

Young Yang, S. Paik, D. Yoon, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Neutrophil Proteinase 3 Induces Diabetes in a Mouse Model of Glucose Tolerance

Soohyun Kim, Jaewoo Hong, Suyoung Bae, 2012, Endocrine research.

Differences in signaling pathways by IL-1beta and IL-18.

C. Dinarello, Soohyun Kim, E. Lewis, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Identification of the most active interleukin‐32 isoform

D. Yoon, Chang-Kwon Lee, C. Dinarello, 2009, Immunology.

Proteinase 3-processed form of the recombinant IL-32 separate domain.

D. Yoon, C. Dinarello, Soohyun Kim, 2008, BMB reports.

Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function

H. Deeg, D. Stirewalt, C. Dinarello, 2008, Proceedings of the National Academy of Sciences.

IL-32–dependent effects of IL-1β on endothelial cell functions

N. Voelkel, C. Dinarello, Soohyun Kim, 2009, Proceedings of the National Academy of Sciences.

Activation of the interleukin‐32 pro‐inflammatory pathway in response to human papillomavirus infection and over‐expressionof interleukin‐32 controls the expression of the humanpapillomavirus oncogene

Young Yang, D. Yoon, Heejong Kim, 2011, Immunology.

Therapeutic benefits of recombinant alpha1-antitrypsin IgG1 Fc-fusion protein in experimental emphysema

E. Gelfand, I. Petrache, A. Joetham, 2021, Respiratory Research.

The Combination of Soluble IL-18Rα and IL-18Rβ Chains Inhibits IL-18-Induced IFN-γ

M. Tsang, C. Dinarello, Soohyun Kim, 2002 .

Role of S100A9 in the development of neutrophilic inflammation in asthmatics and in a murine model.

S. Uh, Choon-Sik Park, Soohyun Kim, 2017, Clinical immunology.

EP TE D M AN U SC R IP T Role of S 100 A 9 in the development of neutrophilic inflammation in asthmatics and in a

S. Uh, Choon-Sik Park, Soohyun Kim, 2017 .

Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.

E. Gelfand, A. Joetham, C. Dinarello, 2004, American journal of respiratory cell and molecular biology.

IL-32γ overexpression accelerates streptozotocin (STZ)-induced type 1 diabetes.

D. Yoon, Soohyun Kim, Jaewoo Hong, 2014, Cytokine.

Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo

Jeong-Sun Kim, Soohyun Kim, Yong-Sung Kim, 2010, Proceedings of the National Academy of Sciences.

Induction of thymocyte apoptosis by systemic administration of concanavalin A in mice: role of TNF‐α, IFN‐γ and glucocorticoids

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2005 .

Interleukin-18 Binding Protein in Immune Regulation and Autoimmune Diseases

Seung Yong Park, Soohyun Kim, S. Park, 2022, Biomedicines.

Tetramethoxy Hydroxyflavone p7F Downregulates Inflammatory Mediators via the Inhibition of Nuclear Factor κB

D. Yoon, J. Ahn, C. Dinarello, 2004, Annals of the New York Academy of Sciences.

Recombinant Human Alpha-1 Antitrypsin-Fc Fusion Protein Reduces Mouse Myocardial Inflammatory Injury After Ischemia–Reperfusion Independent of Elastase Inhibition

Scott W. Rose, B. V. Van Tassell, A. Abbate, 2016, Journal of cardiovascular pharmacology.

Application of a novel cell-permeable peptide-driven protein delivery in mouse blastocysts.

Soohyun Kim, H. Lim, Soyoung Choi, 2013, Reproduction.

Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase

T. Welte, F. Laenger, C. Dinarello, 2013, Proceedings of the National Academy of Sciences.

Suppressing IL-32 in monocytes impairs the induction of the proinflammatory cytokines TNFalpha and IL-1beta.

E. Chan, D. Yoon, C. Dinarello, 2010, Cytokine.

Detection of expressed IL-32 in human stomach cancer using ELISA and immunostaining.

D. Yoon, Heejong Kim, Jung-hee Kim, 2008, Journal of microbiology and biotechnology.

HIV-1 Production Endogenous IL-32 Controls Cytokine and

C. Dinarello, Soohyun Kim, M. Nold, 2008 .

Identification of Constitutively Active Interleukin 33 (IL-33) Splice Variant*

Soohyun Kim, Jaewoo Hong, Suyoung Bae, 2011, The Journal of Biological Chemistry.

Interleukin-32γ Enhances the Production of IL-6 and IL-8 in Fibroblast-Like Synoviocytes Via Erk1/2 Activation

Soohyun Kim, Chang-Keun Lee, B. Yoo, 2010, Journal of Clinical Immunology.

Tumor necrosis factor alpha-induced interleukin-32 is positively regulated via the Syk/protein kinase Cdelta/JNK pathway in rheumatoid synovial fibroblasts.

Soohyun Kim, Hyung Sik Kim, S. Nah, 2009, Arthritis and rheumatism.

Role of IL-32 Gamma on Bone Metabolism in Autoimmune Arthritis

Soohyun Kim, Chang-Keun Lee, B. Yoo, 2018, Immune network.

Effect of interleukin-32gamma on differentiation of osteoclasts from CD14+ monocytes.

Soohyun Kim, Chang-Keun Lee, B. Yoo, 2010, Arthritis and rheumatism.

Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1β and by the induction of endogenous IL-1Ra

L. Joosten, M. Netea, C. Dinarello, 2015, Annals of the rheumatic diseases.

Regulation of Staphylococcus epidermidis-induced IFN-gamma in whole human blood: the role of endogenous IL-18, IL-12, IL-1, and TNF.

M. Netea, G. Fantuzzi, C. Dinarello, 2003, Cytokine.

Interleukin-32 induces the differentiation of monocytes into macrophage-like cells

L. Joosten, M. Netea, C. Dinarello, 2008, Proceedings of the National Academy of Sciences.

Mycobacterium tuberculosis Induces Interleukin-32 Production through a Caspase- 1/IL-18/Interferon-γ-Dependent Mechanism

L. Joosten, M. Netea, E. Chan, 2006, PLoS medicine.

IL-18 E42A mutant is resistant to the inhibitory effects of HPV-16 E6 and E7 oncogenes on the IL-18-mediated immune response.

D. Yoon, D. Cho, C. Dinarello, 2005, Cancer letters.

Mononuclear and NK Cells Production in Human Peripheral Blood g IFN-Papillomavirus 16 Inhibit IL-18-Induced Both E6 and E7 Oncoproteins of Human

D. Yoon, Sue-N. Park, C. Dinarello, 2001 .

Interleukin-32γ attenuates ethanol-induced liver injury by the inhibition of cytochrome P450 2E1 expression and inflammatory responses.

D. Yoon, J. Hong, Dong Hun Lee, 2015, Clinical science.

Individual LPS responsiveness depends on the variation of toll-like receptor (TLR) expression level.

M. Netea, Young Yang, E. Abraham, 2007, Journal of microbiology and biotechnology.

Interleukin-32γ suppresses allergic airway inflammation in mouse models of asthma.

Soohyun Kim, Y. Cho, Tae-Bum Kim, 2014, American journal of respiratory cell and molecular biology.

A proinflammatory cytokine interleukin‐32β promotes the production of an anti‐inflammatory cytokine interleukin‐10

D. Yoon, Heejong Kim, Jeong-Woo Kang, 2009, Immunology.

Development of an interleukin (IL)-33 sandwich ELISA kit specific for mature IL-33

T. Kang, Soohyun Kim, Suyoung Bae, 2016, Journal of immunoassay & immunochemistry.

Differential Gene Regulation by Specific Gain-of-function JNK1 Proteins Expressed in Swiss 3T3 Fibroblasts*

L. Heasley, Soohyun Kim, Sun-Young Han, 2002, The Journal of Biological Chemistry.

Paradoxical effects of constitutive human IL-32γ in transgenic mice during experimental colitis

C. Dinarello, Soohyun Kim, Jaewoo Hong, 2010, Proceedings of the National Academy of Sciences.

Reconstitution of ST2 (IL-1R4) specific for IL-33 activity; no suppression by IL-1Ra though a common chain IL-1R3 (IL-1RAcP) shared with IL-1.

T. Kang, Soohyun Kim, Yong-Sung Kim, 2016, Cytokine.

Effect of lipopolysaccharide (LPS) on mouse model of steroid-induced avascular necrosis in the femoral head (ANFH).

Soohyun Kim, Jaewoo Hong, Siyoung Lee, 2014, Journal of microbiology and biotechnology.

The inhibitory function of Fc-ST2 depends on cell type; IL-1RAcP and ST2 are necessary but insufficient for IL-33 activity

Soohyun Kim, Jaewoo Hong, Y. Cho, 2013, Immunologic research.

The biology of human interleukin-32

C. Dinarello, Soohyun Kim, 2007 .

The Role of Endogenous Interleukin (IL)-18, IL-12, IL-1β, and Tumor Necrosis Factor-α in the Production of Interferon-γ Induced by Candida albicans in Human Whole-Blood Cultures

M. Netea, J. Meer, C. Dinarello, 2002 .

Differential Roles of Interleukin-18 (IL-18) and IL-12 for Induction of Gamma Interferon by Staphylococcal Cell Wall Components and Superantigens

M. Netea, C. Dinarello, Soohyun Kim, 2001, Infection and Immunity.

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8

B. Palmer, C. Garlanda, A. Mantovani, 2015, Proceedings of the National Academy of Sciences.

Effect of Recombinant α1-Antitrypsin Fc-Fused (AAT-Fc) Protein on the Inhibition of Inflammatory Cytokine Production and Streptozotocin-Induced Diabetes

C. Dinarello, Soohyun Kim, Jaewoo Hong, 2013, Molecular Medicine.

Peripheral Blood Neutrophil Activation Patterns Are Associated with Pulmonary Inflammatory Responses to Lipopolysaccharide in Humans1

E. Abraham, J. Nick, C. Dinarello, 2006, The Journal of Immunology.

Development of isoform-specific monoclonal antibodies against human IL-18 binding protein.

Soohyun Kim, Jaewoo Hong, Suyoung Bae, 2010, Hybridoma.

Elevated interleukin-32 expression in granulomatosis with polyangiitis.

Soohyun Kim, Yong-Beom Park, Jaewoo Hong, 2012, Rheumatology.

Characterizing antiviral mechanism of interleukin-32 and a circulating soluble isoform in viral infection.

Soohyun Kim, Sung‐Han Kim, Jaewoo Hong, 2012, Cytokine.

Interleukin-32: a cytokine and inducer of TNFalpha.

D. Yoon, C. Dinarello, Soohyun Kim, 2005, Immunity.

Interleukin-18 and IL-18 Binding Protein

C. Dinarello, Soohyun Kim, G. Kaplanski, 2013, Front. Immunol..

Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)

Sinae Kim, Soohyun Kim, Siyoung Lee, 2017, Immune network.

Unique expression of a small IL-32 protein in the Jurkat leukemic T cell line.

Soohyun Kim, Jun-Ho Lee, Suyoung Bae, 2008, Cytokine.

Generation of anti-proteinase 3 monoclonal antibodies and development of immunological methods to detect endogenous proteinase 3.

Sangmin Kim, Soohyun Kim, Jaewoo Hong, 2010, Hybridoma.

Proteinase 3 is an IL-32 binding protein.

Aharon Rabinkov, C. Dinarello, Soohyun Kim, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Recombinant Fc-IL-18BPc isoform inhibits IL-18-induced cytokine production.

Soohyun Kim, Jaewoo Hong, Siyoung Lee, 2012, Hybridoma.

Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target

Soohyun Kim, Chang-Seon Song, Jaewoo Hong, 2021, Immune network.

SARS-CoV-2 Delta (B.1.617.2) Variant: A Unique T478K Mutation in Receptor Binding Motif (RBM) of Spike Gene

Soohyun Kim, Chang-Seon Song, H. Jhun, 2021, Immune network.

Interleukin-1 homologues IL-1F7b and IL-18 contain functional mRNA instability elements within the coding region responsive to lipopolysaccharide.

C. Dinarello, Soohyun Kim, F. Gamboni-Robertson, 2004, The Biochemical journal.

Suppression of innate inflammation and immunity by interleukin‐37

C. Dinarello, Soohyun Kim, M. Nold, 2016, European journal of immunology.

Overview of interleukin‐18: more than an interferon‐γ inducing factor

G. Fantuzzi, A. Puren, D. Yoon, 1998, Journal of leukocyte biology.

IL-32γ Induces the Maturation of Dendritic Cells with Th1- and Th17-Polarizing Ability through Enhanced IL-12 and IL-6 Production

D. Cho, Soohyun Kim, T. S. Kim, 2011, The Journal of Immunology.

Serum amyloid A predisposes inflammatory tumor microenvironment in triple negative breast cancer

Soohyun Kim, D. Son, R. M. Ignacio, 2019, Oncotarget.

Interleukin-32γ transgenic mice resist LPS-mediated septic shock.

Soohyun Kim, Suyoung Bae, Siyoung Lee, 2014, Journal of microbiology and biotechnology.

Interleukin‐32: A new proinflammatory cytokine involved in hepatitis C virus‐related liver inflammation and fibrosis

H. Tilg, A. Moschen, R. Bartenschlager, 2011, Hepatology.

IL-32γ and Streptococcus pyogenes cell wall fragments synergise for IL-1-dependent destructive arthritis via upregulation of TLR-2 and NOD2

L. Joosten, C. Dinarello, Soohyun Kim, 2010, Annals of the rheumatic diseases.

Rheumatoid Arthritis (ra)

Soohyun Kim, 2022 .

Interleukin-32 in Inflammatory Autoimmune Diseases

Soohyun Kim, 2014, Immune network.

Endogenous IL-32 Controls Cytokine and HIV-1 Production1

C. Dinarello, Soohyun Kim, M. Nold, 2008, The Journal of Immunology.

IL-32, a proinflammatory cytokine in rheumatoid arthritis.

Do-Young Yoon, Pilar Barrera, L. Joosten, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells.

H. Won, Soohyun Kim, W. Choi, 2011, Immunobiology.

Towards a role of interleukin-32 in atherosclerosis.

L. Joosten, M. Netea, C. Dinarello, 2013, Cytokine.

Both E6 and E7 Oncoproteins of Human Papillomavirus 16 Inhibit IL-18-Induced IFN-γ Production in Human Peripheral Blood Mononuclear and NK Cells1

D. Yoon, Sue-N. Park, C. Dinarello, 2001, The Journal of Immunology.

Intracellular interleukin (IL)-1 family cytokine processing enzyme

Soohyun Kim, Youngmin Lee, Hyunwoo Kim, 2016, Archives of pharmacal research.

Cloning and characterization of bovine interleukin-32 beta isoform.

Young Yang, D. Yoon, Soohyun Kim, 2010, Veterinary immunology and immunopathology.

The IL-1 Family Member 7b Translocates to the Nucleus and Down-Regulates Proinflammatory Cytokines1

Sheetal Sharma, R. Gräf, C. Dinarello, 2008, The Journal of Immunology.

Proinflammatory Cytokines the Nucleus and Down-Regulates The IL-1 Family Member 7 b Translocates to and

Sheetal Sharma, R. Gräf, C. Dinarello, 2008 .

Identification of a Critical Ig-Like Domain in IL-18 Receptor α and Characterization of a Functional IL-18 Receptor Complex 1

D. Yoon, C. Dinarello, Soohyun Kim, 2003, The Journal of Immunology.

Rat interleukin-18 binding protein: cloning, expression, and characterization.

C. Dinarello, Soohyun Kim, S. Fuchs, 2002, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

The role of endogenous interleukin (IL)-18, IL-12, IL-1beta, and tumor necrosis factor-alpha in the production of interferon-gamma induced by Candida albicans in human whole-blood cultures.

M. Netea, C. Dinarello, Soohyun Kim, 2002, The Journal of infectious diseases.

Interleukin-1β deficiency results in reduced NF-κB levels in pregnant mice

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2000 .

Interleukin-1 b deﬁciency results in reduced NF- k B levels in pregnant mice

G. Fantuzzi, C. Dinarello, Soohyun Kim, 1999 .

NOD2 triggers an interleukin-32–dependent human dendritic cell program in leprosy

T. Graeber, G. Cheng, Soohyun Kim, 2012, Nature Medicine.

Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis

L. Joosten, E. Chan, I. Orme, 2015, Proceedings of the National Academy of Sciences.

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

C. Garlanda, C. Dinarello, Soohyun Kim, 2014, PLoS pathogens.

Interleukin-32 Gamma Stimulates Bone Formation by Increasing miR-29a in Osteoblastic Cells and Prevents the Development of Osteoporosis

Beom-Jun Kim, J. Koh, Soohyun Kim, 2017, Scientific Reports.

High level of interleukin-32 gamma in the joint of ankylosing spondylitis is associated with osteoblast differentiation

Soohyun Kim, Ye-Soo Park, Chang-Keun Lee, 2015, Arthritis Research & Therapy.

IL-32θ downregulates CCL5 expression through its interaction with PKCδ and STAT3.

D. Yoon, Y. Bak, Jeong-Woo Kang, 2014, Cellular signalling.

IL-37 protects against obesity-induced inflammation and insulin resistance

H. Tilg, L. Joosten, M. Netea, 2014, Nature Communications.

Monoclonal antibodies against recombinant AtHOS15.

Woe-Yeon Kim, D. Yun, Soohyun Kim, 2012, Hybridoma.

Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA.

D. Yoon, Dae-Yeul Yu, C. Dinarello, 2008, Journal of immunological methods.

The apoptotic effect of intercalating agents on HPV-negative cervical cancer C-33A cells

Young Yang, S. Paik, D. Yoon, 2007, Amino Acids.

The inhibitory function of Fc-ST2 depends on cell type; IL-1RAcP and ST2 are necessary but insufficient for IL-33 activity

Soohyun Kim, Jaewoo Hong, Y. Cho, 2013, Immunologic research.

Down modulation of IL‐18 expression by human papillomavirus type 16 E6 oncogene via binding to IL‐18

D. Yoon, Sue-N. Park, Jeong-Woo Kang, 2001, FEBS letters.

Binding Protein Collagen-Induced Arthritis by Murine IL-18 Mechanisms of Inhibition of

Andrea Vondracek, G. Senaldi, C. Dinarello, 2013 .

Anti-inflammatory effects of Artemisia princeps in antigen-stimulated T cells and regulatory T cells.

Soohyun Kim, K. Choi, Jaeho Bae, 2009, The Journal of pharmacy and pharmacology.

Interleukin-32A Cytokine and Inducer of TNFα

D. Yoon, C. Dinarello, Soohyun Kim, 2005 .

IL:32: A new pro-inflammatory cytokine involved in HCV-related liver inflammation and fibrosis

H. Tilg, A. Moschen, R. Bartenschlager, 2009 .

IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.

G. Fantuzzi, C. Dinarello, Soohyun Kim, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Correction: Corrigendum: IL-37 protects against obesity-induced inflammation and insulin resistance

H. Tilg, L. Joosten, M. Netea, 2015, Nature Communications.