J. Grim

发表

Regulation of cell proliferation in a stratified culture system of epithelial cells from prostate tissue

B. Clurman, M. Gustafson, Chang Xu, 2006, Cell and Tissue Research.

B. Clurman, J. Grim, 2003, Trends in cell biology.

Adenovirus-mediated delivery of p16 to p16-deficient human bladder cancer cells confers chemoresistance to cisplatin and paclitaxel.

R. Kratzke, D. Curiel, J. Grim, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

Rob Pieters, Christopher Winter, Giulio Draetta, 2007, The Journal of experimental medicine.

Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism

Patrick J. Paddison, Adam A. Margolin, B. Clurman, 2018, Proceedings of the National Academy of Sciences.

Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression

R. Kratzke, D. Curiel, J. Geradts, 1998, Oncogene.

Fbw7 dimerization determines the specificity and robustness of substrate degradation

B. Clurman, N. Zheng, M. Welcker, 2013, Genes & development.

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

B. Clurman, D. Russell, M. Welcker, 2008, The Journal of cell biology.

Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7.

John Calvin Reed, D. Curiel, C. Rancourt, 1998, Cancer research.

Mantle cell lymphoma relapsed after autologous stem cell transplantation: a single-center experience

J. Grim, N. Burwick, Z. Dong, 2020, Blood research.

Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis.

D. Curiel, J. Grim, R. Alvarez, 1996, Cancer gene therapy.

Gene therapy for ovarian carcinoma.

D. Curiel, C. Rancourt, M. Wang, 1998, Seminars in oncology.

Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects.

D. Curiel, C. Rancourt, J. Grim, 1998, Cancer research.

erbB-2 knockout employing an intracellular single-chain antibody (sFv) accomplishes specific toxicity in erbB-2-expressing lung cancer cells.

D. Curiel, J. Grim, A. Lieber, 1996, American journal of respiratory cell and molecular biology.

An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2

M. Kim, J. Grim, G. Siegal, 1997, Gene Therapy.

The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv

D. Curiel, J. Grim, R. Alvarez, 1998, Journal of Molecular Medicine.

Intracellular expression of the anti-erbB-2 sFv N29 fails to accomplish efficient target modulation.

D. Curiel, J. Grim, R. Alvarez, 1998, Biochemical and biophysical research communications.

Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody.

D. Curiel, J. Grim, R. Alvarez, 1995, Gynecologic oncology.

Cutaneous phaeohyphomycosis in a hematopoietic stem cell transplant patient caused by Alternaria rosae: First case report

J. Grim, J. Clarridge, A. Greenbaum, 2017, Transplant infectious disease : an official journal of the Transplantation Society.

Targeted therapy in gastroesophageal cancers: past, present and future

Janghee Woo, J. Grim, S. Cohen, 2015, Gastroenterology report.

Notch Activation Induces Endothelial Cell Cycle Arrest and Participates in Contact Inhibition: Role of p21Cip1 Repression

B. Clurman, A. Karsan, Laura L. Smith, 2004, Molecular and Cellular Biology.

Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer

B. Clurman, J. Delrow, K. Nakayama, 2012, Molecular and Cellular Biology.

Werner syndrome protein limits MYC-induced cellular senescence.

B. Clurman, D. Russell, R. Monnat, 2003, Genes & development.

A Nucleolar Isoform of the Fbw7 Ubiquitin Ligase Regulates c-Myc and Cell Size

B. Clurman, R. Eisenman, A. Orian, 2004, Current Biology.

Targeted Therapies For Intestinal Tumorigenesis

W. Grady, J. Grim, E. Chiorean, 2015 .

A (heat) shocking development: FBXW7 loss unleashes HSF1 to drive melanoma invasion and metastasis

J. Grim, E. Cho, 2015, Pigment cell & melanoma research.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice

B. Clurman, K. Loeb, J. Grim, 2019, Scientific Reports.

p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability

B. Clurman, M. Welcker, J. Grim, 2007, Oncogene.

Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models

J. Grim, 2013, Gut.

The Dynamic International Prognostic Scoring System for myelofibrosis predicts outcomes after hematopoietic cell transplantation.

H. Deeg, J. Radich, M. Sorror, 2012, Blood.

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice

B. Clurman, K. Loeb, J. Grim, 2019, Scientific Reports.

Targeted eradication of ErbB-2 over-expressing tumor cells employing expression of an intracellular antibody directed against the ErbB-2 oncoprotein

D. Curiel, F. Loechel, J. Grim, 1995 .

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors

B. Clurman, R. Sears, R. Pieters, 2007, The Journal of experimental medicine.