I. Okayasu

H. Kuramoto, I. Okayasu, Y. Kamata, 2006, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.

Significance of p27 as a predicting marker for medroxyprogesterone acetate therapy against endometrial endometrioid adenocarcinoma

H. Kuramoto, I. Okayasu, J. Watanabe, 2005, International Journal of Gynecologic Cancer.

Mucosal high apoptotic activity and low p21WAF1/CIP1 expression and submucosal low proliferative activity in superficially spreading early gastric cancers: Comparison with the penetrating growth type

H. Mitomi, S. Tanabe, I. Okayasu, 2003, Pathology international.

Phase I trial of neoadjuvant preoperative chemotherapy with S-1 and irinotecan plus radiation in patients with locally advanced rectal cancer.

I. Okayasu, Masahiko Watanabe, W. Koizumi, 2007, International journal of radiation oncology, biology, physics.

Possible alternative carcinogenesis pathway featuring microsatellite instability in colorectal cancer stroma

Tsutomu Yoshida, I. Okayasu, K. Yamashita, 2003, British Journal of Cancer.

High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction

K. Saigenji, I. Okayasu, T. Mikami, 2009, British Journal of Cancer.

Invasive behavior of ulcerative colitis-associated carcinoma is related to reduced expression of CD44 extracellular domain: comparison with sporadic colon carcinoma

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2011, Diagnostic pathology.

Tumor budding, myofibroblast proliferation, and fibrosis in obstructing colon carcinoma: the roles of Hsp47 and basic fibroblast growth factor.

Takatoshi Nakamura, Shi‐Xu Jiang, I. Okayasu, 2013, Pathology, research and practice.

Mucosa‐associated bacteria in ulcerative colitis before and after antibiotic combination therapy

M. Sakamoto, Y. Benno, T. Ohkusa, 2005, Alimentary pharmacology & therapeutics.

SURVEILLANCE BY MAGNIFYING ENDOSCOPY IN PATIENTS WITH ULCERATIVE COLITIS

M. Sada, Kiyonori Kobayashi, K. Saigenji, 2005 .

Dye Spraying and Magnifying Endoscopy for Dysplasia and Cancer Surveillance in Ulcerative Colitis

H. Mitomi, M. Sada, Kiyonori Kobayashi, 2004, Diseases of the colon and rectum.

Intratumoral lymphangiogenesis of esophageal squamous cell carcinoma and relationship with regulatory factors and prognosis

S. Tanabe, I. Okayasu, Masahiko Watanabe, 2008, Pathology international.

Evaluation of prognostic factors for the response to S-1 in patients with stage II or III advanced gastric cancer who underwent gastrectomy

M. Azuma, I. Okayasu, Masahiko Watanabe, 2009, Pharmacogenetics and genomics.

β-Catenin mutations and aberrant nuclear expression during endometrial tumorigenesis

M. Saegusa, Tsutomu Yoshida, I. Okayasu, 2001, British Journal of Cancer.

Differential expression of N-cadherin and E-cadherin in normal human tissues.

T. Kameya, Yuichi Sato, I. Okayasu, 2006, Archives of histology and cytology.

Gastric Large Cell Neuroendocrine Carcinomas: A Distinct Clinicopathologic Entity

M. Saegusa, T. Kameya, Shi‐Xu Jiang, 2006, The American journal of surgical pathology.

Diagnostic findings of bronchial brush cytology for pulmonary large cell neuroendocrine carcinomas

M. Hattori, E. Ohno, H. Kuramoto, 2003, Cancer.

The role of the Epstein-Barr virus in the oncogenesis of EBV(+) gastric carcinomas

S. Mori, M. Saegusa, Y. Takano, 1999, Virchows Archiv.

Early genetic instability of both epithelial and stromal cells in esophageal squamous cell carcinomas, contrasted with Barrett's adenocarcinomas

Tsutomu Yoshida, S. Tanabe, I. Okayasu, 2007, Journal of Gastroenterology.

CITED2 is activated in ulcerative colitis and induces p53-dependent apoptosis in response to butyric acid

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2011, Journal of Gastroenterology.

The relationship of lymphocytic thyroiditis to the development of thyroid carcinoma

I. Okayasu, 1997, Endocrine pathology.

More frequent beta-catenin exon 3 mutations in gallbladder adenomas than in carcinomas indicate different lineages.

M. Saegusa, I. Okayasu, T. Mikami, 2001, Cancer research.

Telomerase Activity Significantly Correlates with Chromosome Alterations, Cell Differentiation, and Proliferation in Lung Adenocarcinomas

M. Oshimura, M. Fujiwara, I. Okayasu, 2000, Modern Pathology.

Possible associations among expression of p14ARF, p16INK4a, p21WAF1/CIP1, p27KIP1, and p53 accumulation and the balance of apoptosis and cell proliferation in ovarian carcinomas

M. Saegusa, I. Okayasu, D. Machida B, 2001, Cancer.

DCC expression is related to mucinous differentiation but not changes in expression of p21WAF1/Cip1 and p27Kip1, apoptosis, cell proliferation and human papillomavirus infection in uterine cervical adenocarcinomas

M. Saegusa, I. Okayasu, 1999, British Journal of Cancer.

p53 and p21(WAF1) expression in lymphocytic thyroiditis and thyroid tumors.

M. Fujiwara, I. Okayasu, T. Mikami, 1998, Clinical immunology and immunopathology.

Loss of DCC expression in astrocytomas: relation to p53 abnormalities, cell kinetics, and survival.

M. Saegusa, I. Okayasu, T. Mikami, 2001, Journal of clinical pathology.

Loss of DCC gene expression during ovarian tumorigenesis: relation to tumour differentiation and progression

M. Saegusa, I. Okayasu, D. Machida, 2000, British Journal of Cancer.

Loss of expression of the gene deleted in colon carcinoma (DCC) is closely related to histologic differentiation and lymph node metastasis in endometrial carcinoma

M. Saegusa, I. Okayasu, M. Hashimura, 1999, Cancer.

A case of adenocarcinoma of the small intestine in a Japanese patient with Crohn disease: a report with immunohistochemical and oncogenic analyses.

H. Mitomi, M. Sada, I. Okayasu, 1999, Scandinavian journal of gastroenterology.

Diagnostic and prognostic significance of cyclin A expression in low-grade astrocytomas: comparison with astrogliosis and high-grade tumours

M. Saegusa, I. Okayasu, A. Hara, 2007, Journal of Clinical Pathology.

Absence of human papillomavirus genomic sequences detected by the polymerase chain reaction in oesophageal and gastric carcinomas in Japan.

M. Saegusa, Y. Takano, I. Okayasu, 1997, Molecular pathology : MP.

Relationship between Fecal Bile Acids and the Occurrence of Colorectal Neoplasia in Experimental Murine Ulcerative Colitis

T. Ohkusa, I. Okayasu, K. Kajiura, 1998, Digestion.

Association of Helicobacter pylori‐dependent gastritis with gastric carcinomas in young Japanese patients: histopathological comparison of diffuse and intestinal type cancer cases

I. Okayasu, W. Koizumi, Y. Katoh, 2000, Histopathology.

Differential Diagnosis of Reactive Mesothelial Cells and Malignant Mesothelioma Cells Using the Cell Proliferation Markers Minichromosome Maintenance Protein 7, Geminin, Topoisomerase II Alpha and Ki-67

M. Saegusa, I. Okayasu, J. Watanabe, 2013, Acta Cytologica.

Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in Mongolian gerbils.

T. Ohkusa, N. Sato, I. Okayasu, 2003, Gut.

Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in Mongolian gerbils

T. Ohkusa, N. Sato, I. Okayasu, 2003 .

Significant Increase of Prostaglandin E‐Major Urinary Metabolite in Male Smokers: A Screening Study of Age and Gender Differences Using a Simple Radioimmunoassay

M. Fujiwara, I. Okayasu, I. Sárándi, 2014, Journal of clinical laboratory analysis.

Significant increase of colonic mutated crypts correlates with age in sporadic cancer and diverticulosis cases, with higher frequency in the left‐ than right‐side colorectum

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2006, Cancer science.

Bcl-2 expression and its association with cell kinetics in human gastric carcinomas and intestinal metaplasia

M. Saegusa, Y. Takano, I. Okayasu, 2005, Journal of Cancer Research and Clinical Oncology.

Enhanced cellular proliferative activity and cell death in chronic thyroiditis and thyroid papillary carcinoma

M. Fujiwara, M. Saegusa, I. Okayasu, 2005, Journal of Cancer Research and Clinical Oncology.

Correlations among total colonoscopic findings, clinical symptoms, and laboratory markers in ulcerative colitis

T. Ohkusa, Tsutomu Yoshida, Sumio Watanabe, 2008, Journal of gastroenterology and hepatology.

Appearance of specific mucins recognized by monoclonal antibodies in rat gastric mucosa healing from HCl-induced gastric mucosal damage

K. Saigenji, I. Okayasu, T. Ichikawa, 2004, Journal of Gastroenterology.

Gastric adenomas and superficial adenocarcinomas display distinct patterns of mucin carbohydrate and core protein expression

H. Mitomi, I. Okayasu, K. Hotta, 2000, Histopathology.

Colonic mucin-carbohydrate components in colorectal tumors and their possible relationship to MUC2, p53 and DCC immunoreactivities.

H. Mitomi, M. Saegusa, I. Okayasu, 2000, Pathology, research and practice.

Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: Relevance of cellularity and p27Kip1

I. Okayasu, Masahiko Watanabe, T. Mikami, 2006, Pathology international.

Case Report: Distinctive Diffuse Duodenitis Associated with Ulcerative Colitis

H. Mitomi, I. Okayasu, M. Igarashi, 1997, Digestive Diseases and Sciences.

Prognostic significance of nuclear DJ-1 expression in astrocytoma.

K. Fujii, Yuichi Sato, I. Okayasu, 2010, Anticancer research.

Association of chronic lymphocytic thyroiditis and thyroid papillary carcinoma. A study of surgical cases among Japanese, and white and African Americans

M. Fujiwara, I. Okayasu, N. Rose, 1995, Cancer.

Proteomics of tumor‐specific proteins in cerebrospinal fluid of patients with astrocytoma: Usefulness of gelsolin protein

Toshihide Matsumoto, Yuichi Sato, I. Okayasu, 2009, Pathology international.

Cyclooxygenase-2 and inducible nitric oxide synthase expression in human astrocytic gliomas: correlation with angiogenesis and prognostic significance

I. Okayasu, A. Hara, 2004, Acta Neuropathologica.

Significant high expression of cytokeratins 7, 8, 18, 19 in pulmonary large cell neuroendocrine carcinomas, compared to small cell lung carcinomas

Toshihide Matsumoto, Shi‐Xu Jiang, Yuichi Sato, 2010, Pathology international.

Expression of cell cycle regulatory proteins in the multistep process of oesophageal carcinogenesis: stepwise over‐expression of cyclin E and p53, reduction of p21WAF1/CIP1 and dysregulation of cyclin D1 and p27KIP1

I. Okayasu, N. Kobayashi, M. Ohbu, 2001 .

Submucosal Fibrosis and Basic-Fibroblast Growth Factor-Positive Neutrophils Correlate with Colonic Stenosis in Cases of Ulcerative Colitis

K. Yokoyama, M. Sada, Kiyonori Kobayashi, 2011, Digestion.

High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach

I. Okayasu, T. Mikami, Y. Sato, 2009, British Journal of Cancer.

Effectiveness of antibiotic combination therapy in patients with active ulcerative colitis: A randomized, controlled pilot trial with long-term follow-up

T. Ohkusa, Y. Takei, T. Ogihara, 2005, Scandinavian journal of gastroenterology.

Prediction of Response to 5′-Deoxy- 5-Fluorouridine (5′-DFUR) in Patients with Inoperable Advanced Gastric Cancer by Immunostaining of Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor

K. Saigenji, I. Okayasu, M. Kurihara, 1999, Oncology.

The Role of Vitamin A-Storing Cells (Stellate Cells) in Inflammation and Tumorigenesis

M. Fujiwara, Tsutomu Yoshida, I. Okayasu, 2018, Vitamin A.

Unique characteristics of rectal carcinoma cell lines derived from invasive carcinomas in ulcerative colitis patients

M. Fujiwara, I. Okayasu, K. Yamashita, 2004, Cancer science.

Transcriptional regulation of pro‐apoptotic Par‐4 by NF‐κB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis

M. Saegusa, I. Okayasu, M. Hashimura, 2010, The Journal of pathology.

Development of ulcerative colitis and its associated colorectal neoplasia as a model of the organ‐specific chronic inflammation‐carcinoma sequence

I. Okayasu, 2012, Pathology international.

What's Hot in the Red Journal This Month?

H. Tajiri, T. Ohkusa, N. Sato, 2010, The American Journal of Gastroenterology.

Apoptosis of colon cancer: Comparison with Ki-67 proliferative activity and expression of p53

H. Mitomi, M. Saegusa, Y. Takano, 2005, Journal of Cancer Research and Clinical Oncology.

Effect of Icatibant, a Bradykinin B2 Receptor Antagonist, on the Development of Experimental Ulcerative Colitis in Mice

H. Kitagawa, I. Okayasu, K. Wirth, 1999, Digestive Diseases and Sciences.

Thymic large cell neuroendocrine carcinoma: report of a resected case - a case report

Shi‐Xu Jiang, I. Okayasu, A. Iyoda, 2010, Journal of cardiothoracic surgery.

k‐ras Point Mutations in the Supernatants of Pancreatic Juice and Bile Are Reliable for Diagnosis of Pancreas and Biliary Tract Carcinomas Complementary to Cytologic Examination

I. Okayasu, K. Yamashita, H. Shinoda, 1999, Japanese journal of cancer research : Gann.

Telomerase activity significantly correlates with cell differentiation, proliferation and lymph node metastasis in colorectal carcinomas

M. Oshimura, M. Fujiwara, H. Mitomi, 1998, Journal of Cancer Research and Clinical Oncology.

Apoptosis of colon cancers assessed by in situ DNA nick end‐labeling method

M. Saegusa, Y. Takano, I. Okayasu, 1996, Pathology international.

Progesterone therapy for endometrial carcinoma reduces cell proliferation but does not alter apoptosis

M. Saegusa, I. Okayasu, 1998 .

Bcl‐2 EXPRESSION IS CORRELATED WITH A LOW APOPTOTIC INDEX AND ASSOCIATED WITH PROGESTERONE RECEPTOR IMMUNOREACTIVITY IN ENDOMETRIAL CARCINOMAS

M. Saegusa, I. Okayasu, M. Isono, 1996, The Journal of pathology.

Progesterone therapy for endometrial carcinoma reduces cell proliferation but does not alter apoptosis.

M. Saegusa, I. Okayasu, 1998, Cancer.

Down‐regulation of bcl‐2 expression is closely related to squamous differentiation and progesterone therapy in endometrial carcinomas

M. Saegusa, I. Okayasu, 1997, The Journal of pathology.

Crosstalk between NF‐κB/p65 and β‐catenin/TCF4/p300 signalling pathways through alterations in GSK‐3β expression during trans‐differentiation of endometrial carcinoma cells

M. Saegusa, I. Okayasu, M. Hamano, 2007, The Journal of pathology.

A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas.

M. Saegusa, I. Okayasu, M. Hamano, 2007, Carcinogenesis.

Induction of p16INK4A mediated by β‐catenin in a TCF4‐independent manner: Implications for alterations in p16INK4A and pRb expression during trans‐differentiation of endometrial carcinoma cells

M. Saegusa, I. Okayasu, M. Hamano, 2006, International journal of cancer.

Upregulation of TCF4 expression as a transcriptional target of β-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells

M. Saegusa, I. Okayasu, M. Hamano, 2005, Laboratory Investigation.

Spraying of phenol red dye as a screening test for Helicobacter pylori infection in surgically resected stomach specimens

H. Mitomi, K. Saigenji, I. Okayasu, 2003, Journal of Gastroenterology.

L-Type amino acid transporter 1 (LAT1) expression in lymph node metastasis of gastric carcinoma: Its correlation with size of metastatic lesion and Ki-67 labeling.

Y. Murakumo, I. Okayasu, H. Endou, 2015, Pathology, research and practice.

High expression of L-type amino acid transporter 1 (LAT1) predicts poor prognosis in pancreatic ductal adenocarcinomas

I. Okayasu, H. Endou, W. Koizumi, 2012, Journal of Clinical Pathology.

T‐Cell Regulation in Autoimmune Thyroiditis

K. Beisel, I. Okayasu, Y. Kong, 1981, Immunological reviews.

p53, but not c-Ki-ras, mutation and down-regulation of p21WAF1/CIP1 and cyclin D1 are associated with malignant transformation in gastric hyperplastic polyps.

H. Mitomi, S. Tanabe, K. Saigenji, 2001, American journal of clinical pathology.

Cytogenetic Studies on Colon Carcinomas and Adenomas from Patients with Familial Polyposis Coli

T. Iwama, M. Miyaki, I. Okayasu, 1990 .

Apoptosis and cellular proliferation in oesophageal squamous cell carcinomas: differences between keratinizing and nonkeratinizing types

M. Saegusa, I. Okayasu, M. Ohbu, 2004, Virchows Archiv.

Epidemiological Study of Collagen Disease.

I. Okayasu, H. Kurihara, F. Yanagisawa, 1986 .

Increase in aspergillosis and severe mycotic infection in patients with leukemia and MDS: Comparison of the data from the Annual of the Pathological Autopsy Cases in Japan in 1989, 1993 and 1997

M. Okudaira, I. Okayasu, Toshikazu Yamazaki, 2003, Pathology international.

Microsatellite instability in chronic cholecystitis is indicative of an early stage in gallbladder carcinogenesis.

I. Okayasu, K. Yamashita, T. Mikami, 2003, American journal of clinical pathology.

Prediction of the effect of capecitabine in gastric cancer by immunohistochemical staining of thymidine phosphorylase and dihydropyrimidine dehydrogenase

J. Sakamoto, I. Hyodo, H. Kojima, 2008, Anti-cancer drugs.

Nasopharyngeal Carcinoma and Epstein-Barr Virus Infection in Japanese Patients

M. Hasegawa, I. Okayasu, K. Hirai, 1996 .

Frequent Ki-ras Mutations and Transforming Growth Factor-α Expression in Adenocarcinomas of the Small Intestine: Report of 7 Cases

H. Mitomi, Takatoshi Nakamura, M. Sada, 2004, Digestive Diseases and Sciences.

Significance of cell proliferation markers (Minichromosome maintenance protein 7, topoisomerase IIα and Ki‐67) in cavital fluid cytology: Can we differentiate reactive mesothelial cells from malignant cells?

I. Okayasu, J. Watanabe, K. Kawai, 2009, Diagnostic cytopathology.

Disruption of the p53–p53r2 DNA repair system in ulcerative colitis contributes to colon tumorigenesis

T. Ohkusa, Tsutomu Yoshida, I. Okayasu, 2006, International journal of cancer.

Significant increase of colonic mutated crypts in ulcerative colitis correlatively with duration of illness.

M. Fujiwara, Tsutomu Yoshida, I. Okayasu, 2002, Cancer research.

Advances in Brief Significant Increase of Colonic Mutated Crypts in Ulcerative Colitis Correlatively with Duration of Illness 1

M. Fujiwara, Tsutomu Yoshida, I. Okayasu, 2002 .

Squamous cell carcinoma arising from a seminal vesicular cyst: Possible relationship between chronic inflammation and tumor development

M. Saegusa, Tsutomu Yoshida, I. Okayasu, 2002, Pathology international.

Enhanced epithelial cell turnover associated with p53 accumulation and high p21WAF1/CIP1 expression in ulcerative colitis.

H. Mitomi, I. Okayasu, A. Kakita, 1999, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Significant correlation of morphological remodeling in ulcerative colitis with disease duration and between elevated p53 and p21WAF1 expression in rectal mucosa and neoplastic development

K. Saigenji, I. Okayasu, T. Mikami, 2005, Pathology international.

Prostaglandin E–Major Urinary Metabolite as a Reliable Surrogate Marker for Mucosal Inflammation in Ulcerative Colitis

H. Tajiri, M. Mitsunaga, M. Saruta, 2014, Inflammatory bowel diseases.

Expression of Tumor Suppressor Gene Product p14ARF in Endometrioid Adenocarcinoma of the Uterine Corpus

H. Kuramoto, I. Okayasu, J. Watanabe, 2004, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Comparative Histologic Assessment of Proctocolectomy Specimens from Japanese and American Patients with Ulcerative Colitis with or Without Dysplasia

M. Bronner, H. Mitomi, H. Kanazawa, 2005, International journal of surgical pathology.

New surrogate marker for ulcerative colitis (UC): PGE-major urinary metabolite (PGE-MUM)

M. Fujiwara, I. Okayasu, S. Arihiro, 2018 .

Prostaglandin E-Major Urinary Metabolite as a Biomarker for Inflammation in Ulcerative Colitis: Prostaglandins Revisited

M. Fujiwara, I. Okayasu, S. Arihiro, 2016, Digestion.

Prostaglandin E‐major urinary metabolite diagnoses mucosal healing in patients with ulcerative colitis in remission phase

M. Saruta, I. Okayasu, M. Ikegami, 2022, Journal of gastroenterology and hepatology.

Significant correlations of E-cadherin, catenin, and CD44 variant form expression with carcinoma cell differentiation and prognosis of extrahepatic bile duct carcinomas.

H. Mitomi, M. Saegusa, I. Okayasu, 2001, American journal of clinical pathology.

Clinical usefulness of EUS for active ulcerative colitis.

Kiyonori Kobayashi, K. Saigenji, I. Okayasu, 2007, Gastrointestinal endoscopy.

The gastric hypercellular microleiomyoma as a precursor lesion for clinical gastrointestinal stromal tumors.

T. Terada, I. Okayasu, T. Mikami, 1997, Human pathology.

Commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion: a possible pathogenic mechanism of ulcerative colitis.

H. Tajiri, T. Ohkusa, N. Sato, 2009, Journal of medical microbiology.

Stimulatory effect of estrogen on the growth of endometrial cancer cells is regulated by cell-cycle regulators

H. Kuramoto, I. Okayasu, J. Watanabe, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Autocrine and paracrine roles of VEGF/VEGFR-2 and VEGF-C/VEGFR-3 signaling in angiosarcomas of the scalp and face.

I. Okayasu, T. Mikami, M. Masuzawa, 2010, Human pathology.

Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice.

H. Kitagawa, H. Kitagawa, I. Okayasu, 1998, Cytokine.

Prediction of relapses after interferon‐alpha therapy by hepatitis C virus RNA in peripheral blood mononuclear cells

I. Okayasu, N. Yamamoto, C. Sato, 1995, Journal of medical virology.

Helicobacter pylori is a fragile bacteria when stored at low and ultra‐low temperatures

T. Ohkusa, N. Sato, I. Okayasu, 2004, Journal of gastroenterology and hepatology.

High expression of L‐type amino‐acid transporter 1 (LAT1) in gastric carcinomas: Comparison with non‐cancerous lesions

Yoshiyuki Suzuki, Tsutomu Yoshida, I. Okayasu, 2011, Pathology international.

Expression of a specific mucin type recognized by monoclonal antibodies in the rat gastric mucosa regenerating from acetic acid-induced ulcer.

K. Saigenji, I. Okayasu, K. Hotta, 2001, Scandinavian journal of gastroenterology.

Apoptosis and proliferative activity of non‐Hodgkin's lymphomas: Comparison with expression of bcl‐2, p53 and c‐myc proteins

M. Saegusa, Y. Takano, I. Okayasu, 1997, Pathology international.

Telomere shortening in Barrett's mucosa and esophageal adenocarcinoma and its association with loss of heterozygosity

I. Okayasu, Masahiko Watanabe, T. Mikami, 2009, Scandinavian journal of gastroenterology.

Development of Pyothorax-Associated Pleural Lymphoma in Relation to Focal Cytokinemic Condition and Epstein-Barr Virus Infection

Y. Takano, I. Okayasu, M. Danbara, 1998, Acta Haematologica.

CD44 variant overexpression in gallbladder carcinoma associated with tumor dedifferentiation

M. Koike, H. Mitomi, M. Saegusa, 2001, Cancer.

Association of Bcl‐2 protein expression with gallbladder carcinoma differentiation and progression and its relation to apoptosis

M. Koike, I. Okayasu, T. Mikami, 1999, Cancer.

Apoptosis, proliferative activity and Bcl-2 expression in Epstein-Barr-virus-positive non-Hodgkin's lymphomas

M. Saegusa, Y. Takano, I. Okayasu, 2005, Journal of Cancer Research and Clinical Oncology.

CD44 expression in benign, premalignant, and malignant ovarian neoplasms: relation to tumour development and progression

M. Saegusa, I. Okayasu, M. Hashimura, 1999, The Journal of pathology.

Down‐regulation of CD44 standard and variant isoforms during the development and progression of uterine cervical tumours

M. Saegusa, I. Okayasu, M. Hashimura, 1999, The Journal of pathology.

Dysplasia and carcinoma development in a repeated dextran sulfate sodium‐induced colitis model

T. Ohkusa, Tsutomu Yoshida, I. Okayasu, 2002, Journal of gastroenterology and hepatology.

Association of D2-40 and MMP-1 expression with cyst formation in lung metastatic lesions of cutaneous angiosarcoma on the scalp: immunohistochemical analysis of 23 autopsy cases.

Y. Murakumo, K. Katsuoka, I. Okayasu, 2013, Human pathology.

Lymphatic Tumor Emboli Detected by D2-40 Immunostaining Can More Accurately Predict Lymph-node Metastasis

S. Tanabe, I. Okayasu, Masahiko Watanabe, 2011, World Journal of Surgery.

Primary central nervous system large B-cell lymphoma with prolific, mixed T-cell and macrophage infiltrates, mimicking multiple sclerosis

K. Fujii, K. Iwabuchi, I. Okayasu, 2010, Brain Tumor Pathology.

Detection of the Epstein‐Barr virus genome in cervical neoplasia is closely related to the degree of infiltrating lymphoid cells: A polymerase chain reaction and in situ hybridization approach

M. Saegusa, Y. Takano, I. Okayasu, 1997, Pathology international.

Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis

Tsutomu Yoshida, I. Okayasu, Y. Numata, 2008, Scandinavian journal of gastroenterology.

Expression of bcl‐2 protein in esophageal squamous cell carcinomas and its association with lymph node metastasis

M. Saegusa, I. Okayasu, A. Kakita, 1997, Cancer.

L-type Amino Acid Transporter 1 Expression Increases in Well-Differentiated but Decreases in Poorly Differentiated Endometrial Endometrioid Adenocarcinoma and Shows an Inverse Correlation With p53 Expression

I. Okayasu, H. Endou, H. Mizunuma, 2014, International Journal of Gynecologic Cancer.

Background submucosal cysts in early gastric cancer cases have unique clinicopathologic features suggestive of postgastritis and significant smoking association.

I. Okayasu, T. Mikami, T. Tsuruta, 2007, American journal of clinical pathology.

Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.

Y. Kanai, I. Okayasu, H. Endou, 2001, Biochimica et biophysica acta.

hASH1 expression is closely correlated with endocrine phenotype and differentiation extent in pulmonary neuroendocrine tumors

H. Asamura, K. Nagai, T. Kameya, 2004, Modern Pathology.

L-amino acid transporter 1 may be a prognostic marker for local progression of prostatic cancer under expectant management.

Y. Murakumo, I. Okayasu, H. Endou, 2015, Cancer biomarkers : section A of Disease markers.

[Epidemiology of visceral mycoses in patients with leukemia and MDS - Analysis of the data in annual of pathological autopsy cases in Japan in 1989, 1993, 1997 and 2001].

M. Okudaira, I. Okayasu, Toshikazu Yamazaki, 2006, Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology.

The possible role of bcl–2 expression in the progression of tumors of the uterine cervix

M. Saegusa, Y. Takano, I. Okayasu, 1995, Cancer.

Induction of experimental ulcerative colitis by Fusobacterium varium isolated from colonic mucosa of patients with ulcerative colitis

T. Ohkusa, T. Ogihara, I. Okayasu, 2003, Gut.

Chronic manganese poisoning: A neuropathological study with determination of manganese distribution in the brain

H. Watanabe, S. Ohno, I. Okayasu, 2004, Acta Neuropathologica.

Expression of RACK1 is a novel biomarker in pulmonary adenocarcinomas.

Toshihide Matsumoto, Shi‐Xu Jiang, Yuichi Sato, 2010, Lung cancer.

Hepatoid adenocarcinoma in Barrett’s esophagus associated with achalasia: First case report

K. Saigenji, I. Okayasu, N. Kobayashi, 2002, Pathology international.

Fusobacterium varium localized in the colonic mucosa of patients with ulcerative colitis stimulates species‐specific antibody

T. Ohkusa, N. Sato, I. Okayasu, 2002, Journal of gastroenterology and hepatology.

EFFECT OF PREGNANCY AND ITS RELATED HORMONES ON THE IN VITRO PROLIFERATIVE ACTIVITY OF MOUSE SPLEEN CELLS

I. Okayasu, S. Hatakeyama, K. Hirokawa, 1979 .

FETAL CASE OF XERODERMA PIGMENTOSUM

I. Okayasu, Y. Satoh, Y. Mitoh, 1978 .

Midkine expression in colorectal tumors: Correlation with Ki‐67 labeling in sporadic, but not ulcerative colitis‐associated ones

M. Fujiwara, I. Okayasu, T. Mikami, 2007, Pathology international.

β-Catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells

M. Saegusa, I. Okayasu, M. Hamano, 2004 .

Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells.

M. Saegusa, I. Okayasu, M. Hamano, 2004, The American journal of pathology.

Cytopathic effects and local immune responses in repeated neoadjuvant HSV-tk + ganciclovir gene therapy for prostate cancer

Y. Murakumo, T. Thompson, Masami Watanabe, 2020, Asian journal of urology.

A Kaposi-like variant of splenic angiosarcoma lacking association with human herpesvirus 8.

K. Iwabuchi, M. Saegusa, I. Okayasu, 2002, Archives of pathology & laboratory medicine.

Transcription factor Egr1 acts as an upstream regulator of β‐catenin signalling through up‐regulation of TCF4 and p300 expression during trans‐differentiation of endometrial carcinoma cells

M. Saegusa, I. Okayasu, J. Watanabe, 2008, The Journal of pathology.

Cyclin D2 overexpression and lack of p27 correlate positively and cyclin E inversely with a poor prognosis in gastric cancer cases.

P. V. van Diest, H. Mitomi, Y. Takano, 2000, The American journal of pathology.

Genetic instability on chromosome 17 in the epithelium of non‐polypoid colorectal carcinomas compared to polypoid lesions

Tsutomu Yoshida, K. Saigenji, I. Okayasu, 2006, Cancer science.

Bcl-2 expression and allelic loss of thep53 gene in gastric carcinomas

M. Saegusa, Y. Takano, I. Okayasu, 2005, Journal of Cancer Research and Clinical Oncology.

Upregulation of p16INK4A and Bax in p53 wild/p53-overexpressing crypts in ulcerative colitis-associated tumours

I. Okayasu, T. Mikami, N. Matsumoto, 2004, British Journal of Cancer.

High apoptotic activity and low epithelial cell proliferation with underexpression of p21(WAF1/CIP1) and p27Kip1 of mucinous carcinomas of the colorectum: comparison with well-differentiated type.

H. Mitomi, Takatoshi Nakamura, I. Okayasu, 2002, American journal of clinical pathology.

Cell kinetics, p53 and bcl-2 expression, and c-Ki-ras mutations in flat-elevated tubulovillous adenomas and adenocarcinomas of the colorectum: comparison with polypoid lesions.

H. Mitomi, M. Sada, I. Okayasu, 1999, Scandinavian journal of gastroenterology.

Ki-67, p53, and Bcl-2 expression of serrated adenomas of the colon.

H. Mitomi, M. Sada, I. Okayasu, 1997, The American journal of surgical pathology.

Prostaglandin E-major Urinary Metabolite as a Biomarker for Pediatric Ulcerative Colitis Activity

M. Fujiwara, H. Kishimoto, I. Okayasu, 2017, Journal of pediatric gastroenterology and nutrition.

Papillary thyroid carcinoma with heterotopic ossification is a special subtype with extensive progression.

I. Okayasu, T. Mikami, M. Okamoto, 2013, American journal of clinical pathology.

Mucosal remodeling in long‐standing ulcerative colitis with colorectal neoplasia: Significant alterations of NCAM+ or α‐SMA+ subepithelial myofibroblasts and interstitial cells

Tsutomu Yoshida, M. Sada, I. Okayasu, 2009, Pathology international.

Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug.

M. Saegusa, I. Okayasu, M. Hashimura, 2009, The American journal of pathology.

Apoptosis, cell proliferation and expression of Bcl-2 and Bax in gastric carcinomas: immunohistochemical and clinicopathological study.

M. Saegusa, I. Okayasu, Y. Koshida, 1997, British Journal of Cancer.

Correlation of telomere lengths in normal and cancers tissue in the large bowel.

M. Oshimura, K. Mafune, M. Fujiwara, 2000, Cancer letters.

Significant Correlation of Telomerase Activity in Thyroid Papillary Carcinomas with Cell Differentiation, Proliferation and Extrathyroidal Extension

M. Oshimura, M. Fujiwara, I. Okayasu, 1997, Japanese journal of cancer research : Gann.

Low frequency of promoter methylation of O6-methylguanine DNA methyltransferase and hMLH1 in ulcerative colitis-associated tumors: comparison with sporadic colonic tumors.

J. Jass, Tsutomu Yoshida, I. Okayasu, 2007, American journal of clinical pathology.

Enhanced cellular proliferation and p53 accumulation in gastric mucosa chronically infected with Helicobacter pylori.

H. Mitomi, S. Tanabe, K. Saigenji, 1997, American journal of clinical pathology.

Frequent nuclear β‐catenin accumulation and associated mutations in endometrioid‐type endometrial and ovarian carcinomas with squamous differentiation

M. Saegusa, I. Okayasu, 2001, The Journal of pathology.

Cytoglobin expression of rectal subepithelial myofibroblasts: significant alterations of cytoglobin+ stromal cells in long-standing ulcerative colitis.

M. Fujiwara, Tsutomu Yoshida, M. Sada, 2011, Histology and histopathology.

Bcl-2 is closely correlated with favorable prognostic factors and inversely associated with p53 protein accumulation in endometrial carcinomas: immunohistochemical and polymerase chain reaction/loss of heterozygosity findings

M. Saegusa, I. Okayasu, 2005, Journal of Cancer Research and Clinical Oncology.

Expression of cell cycle regulatory proteins in the multistep process of oesophageal carcinogenesis: stepwise over-expression of cyclin E and p53, reduction of p21(WAF1/CIP1) and dysregulation of cyclin D1 and p27(KIP1).

I. Okayasu, N. Kobayashi, M. Ohbu, 2001, Histopathology.

Bottom‐up cell proliferation with cyclin A and p27Kip1 expression in ulcerative colitis‐associated dysplasia

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2006, Pathology international.

A CASE OF GIANT INFLAMMATORY FIBROID POLYP OF THE COLION, TREATED BY ENDOSCOPIC POLYPECTOMY

H. Mitomi, K. Yokoyama, K. Saigenji, 1997 .

RECTAL GRANULAR‐CELL TUMOR DIFFICULT TO DISTINGUISH FROM CARCINOID TUMOR

K. Yokoyama, M. Sada, K. Saigenji, 2010, Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society.

Apoptosis in Gastric Carcinomas and Its Association with Cell Proliferation and Differentiation

M. Saegusa, Y. Takano, I. Okayasu, 1995, Japanese journal of cancer research : Gann.

Cyclin D1 overexpression in invasive breast cancers: correlation with cyclin-dependent kinase 4 and oestrogen receptor overexpression, and lack of correlation with mitotic activity

M. Saegusa, I. Okayasu, Y. Takano, 1999, Journal of Cancer Research and Clinical Oncology.

Age-dependent differences in tumor cell polarity in endometrial carcinomas

M. Saegusa, I. Okayasu, D. Machida, 2002, Journal of Cancer Research and Clinical Oncology.

Proposal for an Organ-Specific Chronic Inflammation–Remodeling–Carcinoma Sequence

Tsutomu Yoshida, I. Okayasu, M. Ichinoe, 2019, Gastrointestinal Disorders.

Mucosal Remodeling and Alteration of Stromal Microenvironment in Ulcerative Colitis as Related to Colorectal Tumorigenesis

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2011 .

Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender

Tsutomu Yoshida, I. Okayasu, T. Mikami, 2009, Journal of Gastroenterology.

High epithelial and stromal genetic instability of chromosome 17 in ulcerative colitis-associated carcinogenesis.

Tsutomu Yoshida, I. Okayasu, N. Matsumoto, 2003, Cancer research.

Reclassification of the current tumor, node, metastasis staging in pT3 renal cell carcinoma

I. Okayasu, S. Baba, M. Iwamura, 2008, International journal of urology : official journal of the Japanese Urological Association.

Vulnerable Sites and Changes in Mucin in the Rat Small Intestine After Non-steroidal Anti-inflammatory Drugs Administration

K. Saigenji, I. Okayasu, M. Kida, 2010, Digestive Diseases and Sciences.

Effects of indomethacin on the rat small intestinal mucosa: immunohistochemical and biochemical studies using anti-mucin monoclonal antibodies

K. Saigenji, I. Okayasu, T. Iwai, 2009, Journal of Gastroenterology.

Changes in the mucus barrier of the rat during 5-fluorouracil-induced gastrointestinal mucositis

K. Saigenji, I. Okayasu, T. Iwai, 2008, Scandinavian journal of gastroenterology.

TOLERANCE TO THYROGLOBULIN BY ACTIVATING SUPPRESSOR MECHANISMS *

K. Beisel, I. Okayasu, F. Audibert, 1982, Annals of the New York Academy of Sciences.

In vitro T-lymphocyte proliferative response to mouse thyroglobulin in experimental autoimmune thyroiditis.

I. Okayasu, N. Rose, C. David, 1981, Cellular immunology.

Transfer of experimental autoimmune thyroiditis to normal syngeneic mice by injection of mouse thyroglobulin-sensitized T lymphocytes after activation with concanavalin A.

I. Okayasu, 1985, Clinical immunology and immunopathology.

Characterization of resistance to murine experimental autoimmune thyroiditis: duration and afferent action of thyroglobulin- and TSH-induced suppression.

I. Okayasu, Y. Kong, A. A. Giraldo, 1993, Clinical immunology and immunopathology.

A combination of necrosis of autologous thyroid gland and injection of lipopolysaccharide induces autoimmune thyroiditis.

I. Okayasu, S. Hatakeyama, 1984, Clinical immunology and immunopathology.

The difference of susceptibility of target thyroid gland to autoimmune thyroiditis induced by a combination of implantation of thyroid gland and injection of lipopolysaccharide.

I. Okayasu, S. Hatakeyama, 1983, Clinical immunology and immunopathology.

The differences of susceptibility of the target thyroid gland to autoimmune thyroiditis and of antigenicity of thyroid gland for induction of experimental autoimmune thyroiditis.

I. Okayasu, 1986, Clinical Immunology and Immunopathology.

Cell Cannibalism and Nucleus-Fragmented Cells in Voided Urine

M. Hattori, I. Okayasu, Kazumasa Matsumoto, 2007, Acta Cytologica.

HPV type 16 in conjunctival and junctional papilloma, dysplasia, and squamous cell carcinoma.

M. Saegusa, Y. Takano, I. Okayasu, 1995, Journal of clinical pathology.

Genetic alterations of K‐ras may reflect prognosis in stage III colon cancer patients below 60 years of age

K. Yamashita, Takatoshi Nakamura, I. Okayasu, 2011, Journal of surgical oncology.

Case Report: Colitis in Chronic Granulomatous Disease Resembling Crohn's Disease (Comparative Analysis of CD68-Positive Cells Between Two Disease Entities)

H. Mitomi, I. Okayasu, T. Katsumata, 1999, Digestive Diseases and Sciences.

A STUDY ON SO‐CALLED SPLENIC AGENESIS SYNDROME–PATHOLOGICAL EXAMINATION OF TWENTY SEVEN AUTOPSY CASES

I. Okayasu, A. Kajita, W. Mori, 1974, Acta pathologica japonica.

DNA analysis of periampullary cancers.

I. Okayasu, H. Katagiri, M. Endo, 1990, The Bulletin of Tokyo Medical and Dental University.

Prognostic impact of perirenal fat or adrenal gland involvement in patients with pT3b renal cell carcinoma.

I. Okayasu, S. Baba, M. Iwamura, 2007, Urology.

Adult Urology Prognostic Impact of Perirenal Fat or Adrenal Gland Involvement in Patients with pT3b Renal Cell Carcinoma

I. Okayasu, S. Baba, M. Iwamura, 2007 .

Detection of Helicobacter pylori infection in early stage gastric cancer. A comparison between intestinal‐ and diffuse‐type gastric adenocarcinomas

T. Ohkusa, I. Okayasu, Yusuke Saito, 1995, Cancer.

Small gastrointestinal stromal tumor in the stomach: identification of precursor for clinical gastrointestinal stromal tumor using c-kit and α-smooth muscle actin expression.

Y. Murakumo, I. Okayasu, T. Mikami, 2013, Human pathology.

Up-regulation of cyclooxygenase-2 expression in lymphocytic thyroiditis and thyroid tumors: significant correlation with inducible nitric oxide synthase.

M. Fujiwara, I. Okayasu, T. Ichikawa, 2002, American journal of clinical pathology.

Promotion of colorectal neoplasia in experimental murine ulcerative colitis.

T. Ohkusa, I. Okayasu, J. Kanno, 1996, Gut.

Decreased expression of CD44, alpha-catenin, and deleted colon carcinoma and altered expression of beta-catenin in ulcerative colitis-associated dysplasia and carcinoma, as compared with sporadic colon neoplasms.

H. Mitomi, O. Tsuruta, I. Okayasu, 2000, Cancer.

Enzyme histochemical analysis of lymphatic vessels in colon carcinoma: occurrence of lymphangiogenesis within the tumor.

I. Okayasu, A. Kakita, N. Kobayashi, 2005, Hepato-gastroenterology.

Magnetometric evaluation for the effect of chrysotile on alveolar macrophages.

Y. Aizawa, I. Okayasu, M. Okada, 1998, The Tohoku journal of experimental medicine.

The more an ulcerative colitis is repeated, the more the risk of colorectal carcinogenesis is increased in mice.

I. Okayasu, H. Kudo, S. Sakamoto, 2002, Anticancer Research.

Hypomethylation of CD30 CpG islands with aberrant JunB expression drives CD30 induction in Hodgkin lymphoma and anaplastic large cell lymphoma

I. Okayasu, Toshiki Watanabe, M. Kadin, 2008, Laboratory Investigation.

Microsatellite instability in chronic cholecystitis is indicative of an early stage in gallbladder carcinogenesis.

I. Okayasu, K. Yamashita, T. Mikami, 2003, American journal of clinical pathology.

Preventive effect of fluvastatin on ulcerative colitis-associated carcinogenesis in mice.

I. Okayasu, T. Tajima, H. Kudo, 2006, Anticancer research.

[An infant autopsy case of ependymoblastoma with high serum alpha fetoprotein (author's transl)].

I. Okayasu, K. Amano, K. Kitamura, 1980, No shinkei geka. Neurological surgery.

CD44 expression in normal, hyperplastic, and malignant endometrium

M. Saegusa, I. Okayasu, M. Hashimura, 1998, The Journal of pathology.

A Case of amputation neuroma of the biliary tract with obstructive jaundice

I. Okayasu, Masaru Yoshida, N. Takahara, 1981, Gastroenterologia Japonica.

Effects of Long Term, Low Dose Ingestion of Fluoride on the Thyroid Gland in Rats

M. Hayashi, I. Okayasu, C. Date, 1986 .

The 5D4 antibody (anti‐cyclin D1/D2) related antigen: Cytoplasmic staining is correlated to the progression of gastric cancer

Y. Takano, I. Okayasu, A. Kakita, 1998, Pathology international.

Constitutive activity of nuclear transcription factor kappaB is observed in follicular lymphoma.

Tsutomu Yoshida, I. Okayasu, T. Tsuruta, 2010, Journal of clinical and experimental hematopathology : JCEH.

Immunohistochemical localization in rat gastrointestinal tract of a sialomucin species recognized by HCM31, a new anti-mucin monoclonal antibody

K. Saigenji, I. Okayasu, T. Ichikawa, 2002 .

Population changes in immunoglobulin-containing mononuclear cells in dextran sulfate sodium-induced coltitis

T. Ohkusa, Kyoichi Nakamura, I. Okayasu, 1996, Journal of Gastroenterology.

Heparin‐induced thrombocytopenia with multiple organized thrombi accompanied by unusual cholesterin deposition: Autopsy case after long‐term follow up

I. Okayasu, T. Mikami, M. Ichinoe, 2009, Pathology international.

Low epithelial cell proliferation and absence of oncoprotein expression in juvenile polyposis of the stomach, with or without tumors.

H. Mitomi, I. Okayasu, N. Kobayashi, 1997, The American journal of gastroenterology.

Proteomic study of sera from patients with bladder cancer: usefulness of S100A8 and S100A9 proteins.

Toshihide Matsumoto, Yuichi Sato, I. Okayasu, 2010, Cancer genomics & proteomics.

Simplified rapid non‐radioactive PCR‐SSCP method applied to K‐ras mutation analysis

I. Okayasu, K. Yamashita, H. Shinoda, 1996, Pathology international.

Sporadic TP53 transition mutations in chronic cholecystitis are possibly linked to gallbladder carcinogenesis.

I. Okayasu, K. Yamashita, N. Yanagisawa, 2010, Anticancer research.

Novel method for simultaneous analysis of p53 and K-ras mutations and p53 protein expression in single histologic sections.

I. Okayasu, K. Yamashita, H. Shinoda, 2001, Archives of pathology & laboratory medicine.

Markedly elevated cell turnover is characteristic of small, deeply invasive carcinomas of the colorectum

H. Mitomi, I. Okayasu, T. Katsumata, 1999, Cancer.

CURRENT OPINION OF ACTIVITY INDEX FOR COLONOSCOPIC AND HISTOLOGICAL FINDINGS IN ULCERATIVE COLITIS :A PROPOSAL OF NEW ACTIVITY ASSESSMENT BY CUMULATIVE METHOD OF SEVEN POINTS SCORES

T. Ohkusa, N. Sato, I. Okayasu, 2006 .

Unique and selective expression of L-amino acid transporter 1 in human tissue as well as being an aspect of oncofetal protein.

Tsutomu Yoshida, I. Okayasu, H. Endou, 2014, Histology and histopathology.

A microscopic adenocarcinoma of the stomach with pulmonary tumor thrombotic microangiopathy in a 17-year-old male.

I. Okayasu, A. Hara, M. Ichinoe, 2005, Pathology, research and practice.

Changes in Expression of Estrogen Receptors α and β in Relation to Progesterone Receptor and pS2 Status in Normal and Malignant Endometrium

M. Saegusa, I. Okayasu, 2000, Japanese journal of cancer research : Gann.

Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry

Tsutomu Yoshida, Yuichi Sato, I. Okayasu, 2017, Oncology letters.

L‐type amino‐acid transporter 1 as a novel biomarker for high‐grade malignancy in prostate cancer

Y. Kanai, I. Okayasu, H. Endou, 2009, Pathology international.

Mixed-histologic-type submucosal invasive gastric cancer as a risk factor for lymph node metastasis: feasibility of endoscopic submucosal dissection.

S. Tanabe, K. Saigenji, I. Okayasu, 2009, Endoscopy.

High microvascular density is correlated with high VEGF, iNOS and COX‐2 expression in penetrating growth‐type early gastric carcinomas

I. Okayasu, T. Mikami, M. Ichinoe, 2004, Histopathology.

Immunohistochemical Detection of Human Gastrointestinal Glutathione Peroxidase in Normal Tissues and Cultured Cells with Novel Mouse Monoclonal Antibodies

H. Mitomi, I. Okayasu, F. Obata, 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

AN AUTOPSY CASE OF CONGENITAL HEPATIC CELL TUMOR

I. Okayasu, W. Mori, M. Hatanaka, 1974, Acta pathologica japonica.

Telangiectatic Focal Nodular Hyperplasia of the Liver in the Perinatal Period: Case Report

I. Okayasu, M. Ohbu, Nobuyoshi Okamura, 2005, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

AN AUTOPSY CASE OF CONGENITAL GOITER

I. Okayasu, N. Miyagawa, W. Mori, 1973, Acta pathologica japonica.

Abstracts of selected papers presented at the 72nd General Meeting of the Japanese Society of Gastroenterology Niigata, Japan, March 27–29, 1986

K. Hatakeyama, M. Sugiura, H. Mieno, 1987, Gastroenterologia Japonica.

CASE REPORT: Parathyroid Hormone-Related Protein Production by Adenocarcinoma in Barrett's Esophagus Patient with Dermatomyositis

H. Mitomi, T. Kameya, M. Sada, 2001, Digestive Diseases and Sciences.

A case of diffuse cavernous hemangioma of the sigmoid colon.

I. Okayasu, S. Kume, Y. Mishima, 1987 .

Vitamin A Inhibits Development of Dextran Sulfate Sodium-Induced Colitis and Colon Cancer in a Mouse Model

Si-young Song, M. Saegusa, Tsutomu Yoshida, 2016, BioMed research international.

Role of group IIA phospholipase A2 in rat colitis induced by dextran sulfate sodium.

I. Okayasu, Katsutoshi Yamada, H. Arita, 2003, European journal of pharmacology.

Three novel synthetic retinoids, Re 80, Am 580 and Am 80, all exhibit anti-angiogenic activity in vivo.

I. Morita, S. Murota, I. Okayasu, 1993, European journal of pharmacology.

Positive correlation of expression of L-type amino-acid transporter 1 with colorectal tumor progression and prognosis: Higher expression in sporadic colorectal tumors compared with ulcerative colitis-associated neoplasia.

I. Okayasu, H. Endou, T. Mikami, 2020, Pathology, research and practice.

High expression of L-type amino acid transporter 1 as a prognostic marker in bile duct adenocarcinomas

Y. Murakumo, I. Okayasu, H. Endou, 2014, Cancer medicine.

HISTOPATHOLOGICAL AND MORPHOMETRICAL STUDY OF THE HUMAN EPIDIDYMIS AND TESTIS

I. Okayasu, S. Hatakeyama, H. Uchima, 1984, Acta pathologica japonica.

Pathological changes of the various organs occurring in fulminant hepatitis

I. Okayasu, W. Mori, 1975 .

A Rapid and Highly Sensitive In Situ mRNA Hybridization Method With Digoxigenin Labeled cRNA Probes

Shi‐Xu Jiang, Yuichi Sato, I. Okayasu, 2006 .

EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance

M. Saegusa, Tsutomu Yoshida, Shi‐Xu Jiang, 2008, International journal of cancer.

Possible association of active gastritis, featuring accelerated cell turnover and p53 overexpression, with cancer development at anastomoses after gastrojejunostomy. Comparison with gastroduodenostomy.

H. Mitomi, K. Saigenji, I. Okayasu, 2000, American journal of clinical pathology.

Is focal chronic autoimmune thyroiditis an age‐related disease? Differences in incidence and severity between Japanese and British

P. D. Lewis, I. Okayasu, S. Hatakeyama, 1991, The Journal of pathology.

Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer

Y. Murakumo, M. Saegusa, Tsutomu Yoshida, 2020, Journal of Clinical Pathology.

Mucosal microflora from patients with ulcerative colitis ( UC ) and toxicity of mucosal bacteria to Vero cell

T. Ohkusa, I. Okayasu, K. Morita, 2002 .

[8-month neoadjuvant hormonal therapy before radical prostatectomy for high-risk prostate cancer].

S. Egawa, I. Okayasu, S. Baba, 2006, Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.

A case of phlebosclerotic colitis : vasculitis as a possible origin

I. Okayasu, T. Mikami, K. Hatate, 2005 .

Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia.

M. Fujiwara, K. Kuwano, Y. Kaneko, 2017, Respiratory medicine.

A prospective randomized study of amoxycillin and omeprazole with and without metronidazole in the eradication treatment of Helicobacter pylori

S. Tanabe, K. Saigenji, I. Okayasu, 1998, Journal of gastroenterology and hepatology.

Selenium-Dependent Glutathione Peroxidase-GI Is Localized in Basal Granulated Cells of Rat Stomach

I. Okayasu, F. Obata, H. Imai, 2001 .

Correlation of apoptosis with tumour cell differentiation, progression, and HPV infection in cervical carcinoma.

M. Saegusa, Y. Takano, I. Okayasu, 1996, Journal of clinical pathology.

Up‐regulation of CD44 Variant Exon Expression in Endometrial Carcinomas: Analysis of mRNA and Protein Isoforms, and Relation to Clinicopathological Factors

M. Saegusa, I. Okayasu, 1998, Japanese journal of cancer research : Gann.

Cytotoxic evaluation of arsenic compounds in alveolar macrophages in hamsters

Y. Aizawa, M. Kotani, I. Okayasu, 2001 .

In vitro toxicity of gallium arsenide in alveolar macrophages evaluated by magnetometry, cytochemistry and morphology.

Y. Aizawa, I. Okayasu, M. Okada, 1999, The Tohoku journal of experimental medicine.

Significance of Nuclear p-Akt in Endometrial Carcinogenesis: Rapid Translocation of p-Akt Into the Nucleus by Estrogen, Possibly Resulting in Inhibition of Apoptosis

H. Kuramoto, I. Okayasu, J. Watanabe, 2010, International Journal of Gynecologic Cancer.

A new strategy for evaluation of the eradication treatment of Helicobacter pylori: validation of the analysis of mucin composition in human gastric juice.

K. Saigenji, I. Okayasu, W. Koizumi, 2001, Clinica chimica acta; international journal of clinical chemistry.

Pulmonary alveolar proteinosis: diagnosis using routinely processed smears of bronchoalveolar lavage fluid.

I. Okayasu, T. Mikami, M. Yokoyama, 1997, Journal of clinical pathology.

Periportal Stellate Cells in Subjects with Chronic Hepatitis C with a Varied Serum Alanine Aminotransferase Level

M. Fujiwara, I. Okayasu, M. Yamagata, 2004, Comparative hepatology.

Distinctive diffuse duodenitis associated with ulcerative colitis.

H. Mitomi, I. Okayasu, M. Igarashi, 1997, Digestive diseases and sciences.

Expression of CA2 and CA9 carbonic anhydrases in ulcerative colitis and ulcerative colitis-associated colorectal cancer.

Y. Murakumo, Tsutomu Yoshida, M. Sada, 2020, Pathology international.

A high frequency of detection of Helicobacter pylori in whitish exudate of gastric ulcer.

T. Ohkusa, I. Okayasu, K. Fujiki, 1991, Journal of clinical gastroenterology.

Changes in bacterial phagocytosis of macrophages in experimental ulcerative colitis.

I. Okayasu, A. Araki, T. Ohkusa, 1995, Digestion.

Bacterial invasion into the colonic mucosa in ulcerative colitis

T. Ohkusa, I. Okayasu, Y. Ozaki, 1993, Journal of gastroenterology and hepatology.

Inhibitory Effects of Bifidobacterium longum on Experimental Ulcerative Colitis Induced in Mice by Synthetic Dextran Sulfate Sodium

T. Ohkusa, M. Fujiwara, I. Okayasu, 2003, Digestion.

Antibiotic combination therapy in patients with chronic ulcerative colitis

T. Ohkusa, Y. Takei, T. Ogihara, 2003 .

Pancreatic alpha fetoprotein-producing acinar cell carcinoma : An autopsy case report

I. Okayasu, M. Kida, N. Yanagisawa, 2005 .

Cancer in collagen disease. A statistical analysis by reviewing the annual of pathological autopsy cases (nippon boken shuho) in Japan

I. Okayasu, H. Kurihara, F. Yanagisawa, 1984, Cancer.

ABNORMAL INTRACRANIAL VASCULAR NETWORKS (“MOYAMOYA” DISEASE), POSSIBLY DUE TO OCCLUSION OF BILATERAL INTERNAL CAROTID ARTERIES — A CASE REPORT WITH HISTOMETRICAL ANALYSIS —

I. Okayasu, Masaaki Yamamoto, A. Kajita, 1976, Acta pathologica japonica.

Effect of anti-Helicobacter pylori IgG antibody titer following eradication of Helicobacter pylori infection.

S. Tanabe, K. Saigenji, I. Okayasu, 2003, Hepato-Gastroenterology.

Significant Increase in Prostaglandin E-Main Urinary Metabolite by Laxative Administration: Comparison with Ulcerative Colitis

M. Fujiwara, I. Okayasu, Y. Kase, 2000, Digestion.

Utility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis

M. Saruta, Tsutomu Yoshida, I. Okayasu, 2023, Scientific reports.

Advances in Brief High Epithelial and Stromal Genetic Instability of Chromosome 17 in Ulcerative Colitis-associated Carcinogenesis 1

Tsutomu Yoshida, I. Okayasu, N. Matsumoto, 2003 .

Multiple carcinoid tumors of the stomach with hypergastrinemia.

I. Okayasu, H. Habu, T. Nosaka, 1992, The American journal of gastroenterology.

Down‐regulation of CD44 standard and variant isoforms during the development and progression of uterine cervical tumours

M. Saegusa, I. Okayasu, M. Hashimura, 1999, The Journal of pathology.

Cyclin D2, but not cyclin D1, overexpression closely correlates with gastric cancer progression and prognosis

Y. Takano, I. Okayasu, Y. Kato, 1999, The Journal of pathology.

A HISTOCHEMICAL and ELECTRON MICROSCOPICAL STUDY OF SO‐CALLED INTRAVENOUS FAT PIGMENT

I. Okayasu, Wataru Mori, Isao Okayasu, 1974, Acta pathologica japonica.

Up‐regulation and nuclear localization of β‐catenin in endometrial carcinoma in response to progesterone therapy

H. Kuramoto, M. Saegusa, Tsutomu Yoshida, 2003, Cancer science.

Down‐regulation of bcl‐2 expression is closely related to squamous differentiation and progesterone therapy in endometrial carcinomas

M. Saegusa, I. Okayasu, 1997, The Journal of pathology.

HISTOPATHOLOGICAL STUDY OF CONGENITAL CYSTIC KIDNEYS WITH SPECIAL REFERENCE TO THE MULTICYSTIC, DYSPLASTIC TYPE

I. Okayasu, A. Kajita, 1978, Acta pathologica japonica.

A new possible lung cancer marker: VGF detection from the conditioned medium of pulmonary large cell neuroendocrine carcinoma-derived cells using secretome analysis.

T. Kameya, Toshihide Matsumoto, Shi‐Xu Jiang, 2009, The International journal of biological markers.

A New Possible Lung Cancer Marker: VGF Detection from the Conditioned Medium of Pulmonary Large Cell Neuroendocrine Carcinoma–Derived Cells using Secretome Analysis

T. Kameya, Toshihide Matsumoto, Shi‐Xu Jiang, 2009 .

Clinical Significance of Human Papillomavirus Genotype by Linear Array Assay in Japanese Women With Uterine Cervical Lesions and Type 16 Physical Status by In Situ Hybridization

I. Okayasu, J. Watanabe, Y. Nishimura, 2009, International Journal of Gynecologic Cancer.

Obliterative arteritis with nitric oxide synthase and HLA-DR expression in Crohn's colitis.

H. Mitomi, I. Okayasu, T. Katsumata, 2001, Hepato-Gastroenterology.

Preventive effect of 1-(2-tetrahydrofuryl)-5-fluorouracil in combination with uracil on colonic carcinogenesis induced by 1,2-dimethylhydrazine in rats.

T. Iwama, I. Okayasu, H. Kudo, 1997, Cancer detection and prevention.

carcinoma . papilloma , dysplasia , and squamous cell HPV type 16 in conjunctival and junctional

M. Saegusa, Y. Takano, I. Okayasu, 2022 .

An aggressive desmoid tumor in a patient with familial adenomatous polyposis: immunohistochemical findings.

H. Mitomi, I. Okayasu, N. Arai, 1999 .

An aggressive desmoid tumor in a patient with familial adenomatous polyposis: immunohistochemical findings

H. Mitomi, I. Okayasu, N. Arai, 1999, American Journal of Gastroenterology.

Helicobacter pylori infection induces duodenitis and superficial duodenal ulcer in Mongolian gerbils

T. Ohkusa, N. Sato, I. Okayasu, 2003, Gut.

Genetic alterations of K‐ras may reflect prognosis in stage III colon cancer patients below 60 years of age

K. Yamashita, Takatoshi Nakamura, I. Okayasu, 2011, Journal of surgical oncology.