J. Sinnett-Smith

发表

Insulin reduces the requirement for EGFR transactivation in bombesin-induced DNA synthesis.

E. Rozengurt, C. Santiskulvong, J. Sinnett-Smith, 2004, Biochemical and biophysical research communications.

Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser552.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2016, American journal of physiology. Cell physiology.

Early signals underlying the induction of the c-fos and c-myc genes in quiescent fibroblasts: studies with bombesin and other growth factors.

E. Rozengurt, J. Sinnett-Smith, Enrique Rozengurt, 1988, Progress in nucleic acid research and molecular biology.

Protein Kinase D Mediates Mitogenic Signaling by Gq-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser744 and Ser748 Phosphorylation*

S. H. Young, E. Rozengurt, R. Waldron, 2009, Journal of Biological Chemistry.

Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells.

E. Rozengurt, J. Sinnett-Smith, Xiaohua Jiang, 2009, Biochemical and biophysical research communications.

G Protein-coupled Receptor Activation Rapidly Stimulates Focal Adhesion Kinase Phosphorylation at Ser-843

E. Rozengurt, J. Sinnett-Smith, R. Fan, 2005, Journal of Biological Chemistry.

Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain.

Á. Valverde, E. Rozengurt, J. Sinnett-Smith, 1994, Proceedings of the National Academy of Sciences of the United States of America.

[d-Arg1,d-Trp5,7,9,Leu11]Substance P Inhibits Bombesin-induced Mitogenic Signal Transduction Mediated by Both Gq and G12 in Swiss 3T3 Cells*

E. Rozengurt, C. Santiskulvong, J. Sinnett-Smith, 2000, The Journal of Biological Chemistry.

Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS).

D. Leopoldt, E. Rozengurt, J. Sinnett-Smith, 2001, Experimental cell research.

Protein Kinase D Potentiates DNA Synthesis and Cell Proliferation Induced by Bombesin, Vasopressin, or Phorbol Esters in Swiss 3T3 Cells*

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2001, The Journal of Biological Chemistry.

Large induction of c-Myc is not essential for the mitogenic response of Swiss 3T3 fibroblasts.

J. Moore, G. Evan, T. Littlewood, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

B. Aggarwal, K. Harikumar, Z. Tong, 2010, Molecular Cancer Therapeutics.

Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Ligation of HLA Class I Molecules Induces YAP Activation through Src in Human Endothelial Cells

E. Reed, E. Rozengurt, J. Sinnett-Smith, 2020, The Journal of Immunology.

Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway.

E. Rozengurt, J. Sinnett-Smith, L. Paolucci, 2000 .

Lysophosphatidic acid rapidly induces protein kinase D activation through a pertussis toxin-sensitive pathway.

E. Rozengurt, J. Sinnett-Smith, L. Paolucci, 2000, American journal of physiology. Cell physiology.

Intracellular Ca 2 oscillations generated via the Ca 2-sensing receptor are mediated by negative feedback by PKC at Thr 888

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2014 .

Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2014, American journal of physiology. Cell physiology.

TNF-α and LPA promote synergistic expression of COX-2 in human colonic myofibroblasts: role of LPA-mediated transactivation of upregulated EGFR

E. Rozengurt, J. Sinnett-Smith, James Yoo, 2013, BMC Gastroenterology.

PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2013, PloS one.

Ligation of HLA class I molecules induces Yes-Associated Protein (YAP) activation through Src in human endothelial cells

E. Reed, E. Rozengurt, J. Sinnett-Smith, 2021 .

Regulated Nucleocytoplasmic Transport of Protein Kinase D in Response to G Protein-coupled Receptor Activation*

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2001, The Journal of Biological Chemistry.

Vasoactive intestinal peptide synergistically stimulates DNA synthesis in mouse 3T3 cells: role of cAMP, Ca2+, and protein kinase C.

E. Rozengurt, J. Sinnett-Smith, R. Zurier, 1988, Experimental cell research.

Bombesin induction of c‐fos and c‐myc proto‐oncogenes in Swiss 3T3 cells: Significance for the mitogenic response

E. Rozengurt, J. Sinnett-Smith, 1987, Journal of cellular physiology.

Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2012, American journal of physiology. Gastrointestinal and liver physiology.

CALL FOR PAPERS Cell Signaling: Proteins, Pathways and Mechanisms Positive cross talk between protein kinase D and -catenin in intestinal epithelial cells: impact on -catenin nuclear localization and phosphorylation at Ser

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2016 .

Platelet-derived growth factor treatment decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells.

M. Collins, E. Rozengurt, J. Sinnett-Smith, 1983, The Journal of biological chemistry.

CCKB/gastrin receptor mediates synergistic stimulation of DNA synthesis and cyclin D1, D3, and E expression in Swiss 3T3 cells

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2001 .

Characterization of a bombesin receptor on Swiss mouse 3T3 cells by affinity cross‐linking

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1988, Journal of cellular biochemistry.

Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2017, The Journal of Biological Chemistry.

Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate.

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1992, The Journal of biological chemistry.

Bombesin stimulation of fibroblast mitogenesis: specific receptors, signal transduction and early events.

E. Rozengurt, J. Sinnett-Smith, 1990, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Intracellular Ca 2 + oscillations generated via the Ca 2-sensing receptor are 1 mediated by negative feedback by PKC α at Thr 888 2 3 4

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2013 .

Vasopressin‐induced intracellular redistribution of protein kinase D in intestinal epithelial cells

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2003, Journal of cellular physiology.

Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.

C. Turner, E. Rozengurt, J. Sinnett-Smith, 1993, The Journal of biological chemistry.

Protein kinase D: a novel target for diacylglycerol and phorbol esters.

E. Rozengurt, J. Sinnett-Smith, J. Zugaza, 1997, Biochemical Society transactions.

Protein kinase D inhibits plasma membrane Na+/H+exchanger activity.

E. Rozengurt, J. Sinnett-Smith, M. Avkiran, 1999, American journal of physiology. Cell physiology.

Phorbol esters and diacylglycerol inhibit vasopressin-induced increases in cytoplasmic-free Ca2+ and 45Ca2+ efflux in Swiss 3T3 cells.

A. López-Rivas, E. Rozengurt, J. Sinnett-Smith, 1986, Experimental cell research.

Signal transduction in mitogenesis: further evidence for multiple pathways.

H. Mehmet, E. Rozengurt, J. Sinnett-Smith, 1988, Cold Spring Harbor symposia on quantitative biology.

Signalling mitogenesis in 3T3 cells: role of Ca2+-sensitive, phospholipid-dependent protein kinase.

E. Rozengurt, J. Sinnett-Smith, A. Rodríguez-Peña, 1985, Ciba Foundation symposium.

Bombesin receptor in membranes from Swiss 3T3 cells. Binding characteristics, affinity labelling and modulation by guanine nucleotides.

E. Rozengurt, J. Sinnett-Smith, W. Lehmann, 1990, The Biochemical journal.

Protein kinase D1 mediates class IIa histone deacetylase phosphorylation and nuclear extrusion in intestinal epithelial cells: role in mitogenic signaling.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2014, American journal of physiology. Cell physiology.

Vasopressin regulation of cell growth in Swiss 3T3 cells

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1993, Regulatory Peptides.

Statins Inhibit Inflammatory Cytokine Production by Macrophages and Acinar-to-Ductal Metaplasia of Pancreatic Cells

G. Eibl, O. Hines, E. Rozengurt, 2022, Gastro hep advances.

Diacylglycerol treatment rapidly decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells

E. Rozengurt, J. Sinnett-Smith, 1985, Journal of cellular physiology.

Production of PDGF‐like growth factor by breast cancer cell lines

J. Taylor‐Papadimitriou, E. Rozengurt, J. Sinnett-Smith, 1985, International journal of cancer.

Characterization of the Bombesin/Gastrin-Releasing Peptide Receptor in Swiss 3T3 Fibroblasts

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1993 .

Bombesin receptor from Swiss 3T3 cells Affinity chromatography and reconstitution into phospholipid vesicles

E. Rozengurt, J. Sinnett-Smith, A. Coffer, 1990, FEBS letters.

Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts.

E. Rozengurt, J. Sinnett-Smith, James Yoo, 2011, Biochemical and biophysical research communications.

Interplay between fatty acids, SCD, mTORC1 and YAP/TAZ in promoting hepatocellular carcinoma

E. Rozengurt, J. Sinnett-Smith, J. Pisegna, 2022, Gastro Hep Advances.

EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin.

E. Rozengurt, C. Santiskulvong, J. Sinnett-Smith, 2001, American journal of physiology. Cell physiology.

Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.

E. Rozengurt, J. Sinnett-Smith, M. Coombs, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. I. Activation of protein kinase C and inhibition of epidermal growth factor binding

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1986, The Journal of cell biology.

Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival

G. Eibl, E. Rozengurt, J. Sinnett-Smith, 2018, Signal Transduction and Targeted Therapy.

Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.

E. Rozengurt, J. Sinnett-Smith, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Crosstalk between Insulin/Insulin-like Growth Factor-1 Receptors and G Protein-Coupled Receptor Signaling Systems: A Novel Target for the Antidiabetic Drug Metformin in Pancreatic Cancer

E. Rozengurt, J. Sinnett-Smith, K. Kisfalvi, 2010, Clinical Cancer Research.

in Pancreatic Cancer Systems: A Novel Target for the Antidiabetic Drug Metformin Receptors and G Protein-Coupled Receptor Signaling Crosstalk between Insulin/Insulin-like Growth Factor-1

E. Rozengurt, J. Sinnett-Smith, K. Kisfalvi, 2010 .

Early events elicited by bombesin and structurally related peptides in quiescent Swiss 3T3 cells. II. Changes in Na+ and Ca2+ fluxes, Na+/K+ pump activity, and intracellular pH

A. López-Rivas, E. Rozengurt, J. Sinnett-Smith, 1986, The Journal of cell biology.

Bombesin, Lysophosphatidic Acid, and Epidermal Growth Factor Rapidly Stimulate Focal Adhesion Kinase Phosphorylation at Ser-910

E. Rozengurt, J. Sinnett-Smith, E. Salazar, 2003, Journal of Biological Chemistry.

Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2016, The Journal of Biological Chemistry.

Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth.

G. Eibl, E. Rozengurt, J. Sinnett-Smith, 2009, Cancer research.

Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2007, Endocrinology.

Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.

S. H. Young, Aune Moro, G. Eibl, 2015, American journal of physiology. Cell physiology.

Prostaglandin E2 activates the mTORC1 pathway through an EP 4 /cAMP/ PKA- and EP 1 /Ca 2 -mediated mechanism in the human pancreatic carcinoma

S. H. Young, Aune Moro, G. Eibl, 2015 .

Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells

S. H. Young, H. Soares, G. Eibl, 2014, PloS one.

Protein kinase D (PKD) activation in intact cells through a protein kinase C‐dependent signal transduction pathway.

E. Rozengurt, J. Sinnett-Smith, J. Van Lint, 1996, The EMBO journal.

Expression and Characterization of PKD, a Phorbol Ester and Diacylglycerol-stimulated Serine Protein Kinase (*)

E. Rozengurt, J. Sinnett-Smith, J. Van Lint, 1995, The Journal of Biological Chemistry.

Different Patterns of Akt and ERK Feedback Activation in Response to Rapamycin, Active-Site mTOR Inhibitors and Metformin in Pancreatic Cancer Cells

H. Soares, E. Rozengurt, J. Sinnett-Smith, 2013, PloS one.

M1968 Metformin Disrupts Crosstalk Between G Protein-Coupled Receptor and Insulin Receptor Signaling Systems and Inhibits Pancreatic Cancer Growth

S. H. Young, G. Eibl, E. Rozengurt, 2010 .

Direct growth‐inhibitory effects of prostaglandin E2 in pancreatic cancer cells in vitro through an EP4/PKA‐mediated mechanism

G. Eibl, E. Rozengurt, J. Sinnett-Smith, 2017, Surgery.

Bombesin, Vasopressin, Endothelin, Bradykinin, and Platelet-derived Growth Factor Rapidly Activate Protein Kinase D through a Protein Kinase C-dependent Signal Transduction Pathway*

E. Rozengurt, R. Waldron, J. Sinnett-Smith, 1997, Journal of Biological Chemistry.

TNF-α induces upregulation of EGFR expression and signaling in human colonic myofibroblasts.

R. Edwards, E. Rozengurt, J. Sinnett-Smith, 2012, American journal of physiology. Gastrointestinal and liver physiology.

TNF-α potentiates lysophosphatidic acid-induced COX-2 expression via PKD in human colonic myofibroblasts.

E. Rozengurt, J. Sinnett-Smith, James Yoo, 2011, American journal of physiology. Gastrointestinal and liver physiology.

TNF-α Potentiates Lysophosphatidic Acid-Induced COX-2 Expression via the LPA1 Receptor, GIα and PKD in Human Colonic Myofibroblasts

E. Rozengurt, J. Sinnett-Smith, James Yoo, 2011 .

Protein kinase D1 promotes anchorage‐independent growth, invasion, and angiogenesis by human pancreatic cancer cells

B. Aggarwal, Z. Tong, B. Sung, 2011, Journal of cellular physiology.

CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway.

E. Rozengurt, R. Waldron, S. Guha, 2010, Biochemical and biophysical research communications.

Protein kinase D mediates synergistic expression of COX-2 induced by TNF-{alpha} and bradykinin in human colonic myofibroblasts.

E. Rozengurt, L. Slice, J. Sinnett-Smith, 2009, American journal of physiology. Cell physiology.

Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model

Aune Moro, G. Eibl, O. Hines, 2018, Scientific Reports.

Ectopic expression of the heterotrimeric G15 protein in pancreatic carcinoma and its potential in cancer signal transduction.

A. Scarpa, C. Bassi, E. Rozengurt, 2013, Cellular signalling.

Differential PKC-dependent and -independent PKD activation by G protein α subunits of the Gq family: selective stimulation of PKD Ser⁷⁴⁸ autophosphorylation by Gαq.

E. Rozengurt, R. Waldron, J. Sinnett-Smith, 2012, Cellular signalling.

Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2+ mobilization, and the actin cytoskeleton.

Á. Valverde, E. Rozengurt, J. Sinnett-Smith, 1993, The Journal of biological chemistry.

Protein kinase D (PKD): a novel target for diacylglycerol and phorbol esters.

Á. Valverde, E. Rozengurt, J. Sinnett-Smith, 1995, Mutation research.

Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice

Gang Li, Aune Moro, V. Go, 2017, PloS one.

Mitogenic signalling through the bombesin receptor: role of a guanine nucleotide regulatory protein

I. Fabregat, E. Rozengurt, J. Sinnett-Smith, 1990, Journal of Cell Science.

Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma.

J. Nemunaitis, C. Ricordi, E. Rozengurt, 2016, Current molecular medicine.

Protein Kinase D Potentiates DNA Synthesis Induced by Gq-coupled Receptors by Increasing the Duration of ERK Signaling in Swiss 3T3 Cells*

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2004, Journal of Biological Chemistry.

Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells.

A. López-Rivas, E. Rozengurt, J. Sinnett-Smith, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Sequential Protein Kinase C (PKC)-dependent and PKC-independent Protein Kinase D Catalytic Activation via Gq-coupled Receptors

E. Rozengurt, R. Waldron, J. Sinnett-Smith, 2008, Journal of Biological Chemistry.

Metformin Inhibits the Growth of Human Pancreatic Cancer Xenografts

Aune Moro, G. Eibl, E. Rozengurt, 2013, Pancreas.

Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal Crypts*

E. Rozengurt, J. Sinnett-Smith, N. Rozengurt, 2010, The Journal of Biological Chemistry.

Deficiency in hormone-sensitive lipase accelerates the development of pancreatic cancer in conditional KrasG12D mice

Jonathan C. King, Aune Moro, G. Eibl, 2018, BMC Cancer.

Protein kinase D2 potentiates MEK/ERK/RSK signaling, c‐Fos accumulation and DNA synthesis induced by bombesin in Swiss 3T3 cells

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2007, Journal of cellular physiology.

Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin

J. Nemunaitis, F. Brunicardi, E. Rozengurt, 2014, Front. Physiol..

Dissociation of c-fos induction from protein kinase C-independent mitogenesis in Swiss 3T3 cells.

J. Moore, G. Evan, H. Mehmet, 1989, Oncogene research.

Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells.

E. Rozengurt, J. Sinnett-Smith, Xiaohua Jiang, 2007, Cellular signalling.

The lipid-associated 3D structure of SPA, a broad-spectrum neuropeptide antagonist with anticancer properties.

D. Keire, E. Rozengurt, J. Sinnett-Smith, 2006, Biophysical journal.

Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice

G. Eibl, E. Rozengurt, J. Sinnett-Smith, 2019, PloS one.

Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2017, Molecular Cancer Research.

Role of protein kinase D signaling in pancreatic cancer.

E. Rozengurt, S. Guha, J. Sinnett-Smith, 2010, Biochemical pharmacology.

Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells.

J. Gil, E. Rozengurt, J. Sinnett-Smith, 1991, Proceedings of the National Academy of Sciences of the United States of America.

G Protein-coupled Receptor-mediated Phosphorylation of the Activation Loop of Protein Kinase D

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2004, Journal of Biological Chemistry.

Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells.

E. Rozengurt, J. Sinnett-Smith, I. Zachary, 1991, The Journal of biological chemistry.

Protein Kinase D 1 mediates Class IIa Histone Deacetylase Phosphorylation and 1 Nuclear Extrusion in Intestinal Epithelial Cells : Role in Mitogenic Signaling 2 3

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2014 .

Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK.

E. Rozengurt, J. Sinnett-Smith, Enrique Rozengurt, 2013, Biochemical and biophysical research communications.

Solubilization of the bombesin receptor from Swiss 3T3 cell membranes

I. Fabregat, E. Rozengurt, J. Sinnett-Smith, 1990, FEBS letters.

Differential induction of c-fos and c-myc by cyclic AMP in Swiss 3T3 cells: significance for the mitogenic response.

J. Moore, G. Evan, H. Mehmet, 1988, Oncogene research.

TNF-α Induces Up-Regulation of EGFR Expression and Signaling in Human 4

R. Edwards, E. Rozengurt, J. Sinnett-Smith, 2012 .

Bombesin Stimulation of p 125 Focal Adhesion Kinase Tyrosine Phosphorylation

Á. Valverde, J. Sinnett-Smith, I. Zachary, 2001 .

G protein-coupled receptor-mediated phosphorylation of the activation loop of protein kinase D: dependence on plasma membrane translocation and protein kinase Cepsilon.

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2004, The Journal of biological chemistry.

Gastrointestinal peptide signalling in health and disease.

E. Rozengurt, S. Guha, J. Sinnett-Smith, 2002, The European journal of surgery. Supplement. : = Acta chirurgica. Supplement.

RNA interference reveals a differential role of FAK and Pyk2 in cell migration, leading edge formation and increase in focal adhesions induced by LPA in intestinal epithelial cells

E. Rozengurt, J. Sinnett-Smith, E. Zhukova, 2006, Journal of cellular physiology.

Intracellular Ca2+ oscillations generated via the Ca2+-sensing receptor are mediated by negative feedback by PKCα at Thr888.

S. H. Young, E. Rozengurt, J. Sinnett-Smith, 2014, American journal of physiology. Cell physiology.

Metformin disrupts crosstalk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth.

G. Eibl, E. Rozengurt, J. Sinnett-Smith, 2009, Cancer research.

[D-Arg(1),D-Trp(5,7,9),Leu(11)]Substance P inhibits bombesin-induced mitogenic signal transduction mediated by both G(q) and G(12) in Swiss 3T3cells.

E. Rozengurt, C. Santiskulvong, J. Sinnett-Smith, 2000, The Journal of biological chemistry.

Protein Kinase D Mediates Synergistic Expression of Cox-2 Induced by Tnf-␣ and Bradykinin in Human Colonic Myofibroblasts

E. Rozengurt, L. Slice, J. Sinnett-Smith, 2022 .

Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice

G. Eibl, E. Rozengurt, R. Waldron, 2023, Scientific reports.

Protein kinase D inhibits plasma membrane Na 1 /H 1 exchanger activity

E. Rozengurt, J. Sinnett-Smith, M. Avkiran, 1999 .

CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway.

E. Rozengurt, R. Waldron, S. Guha, 2010, Biochemical and biophysical research communications.