D. Han

发表

Antitumor effect of the cinnamaldehyde derivative CB403 through the arrest of cell cycle progression in the G2/M phase.

Ha-won Jeong, D. Han, K. Son, 2003, Biochemical pharmacology.

Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell lines.

Ho Jae Lee, Ha-won Jeong, D. Han, 2002, Bioorganic & medicinal chemistry.

Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.

D. Han, B. Kwon, Dae-Seop Shin, 2009, Cancer research.

Synthesis and biological evaluation of dimeric cinnamaldehydes as potent antitumor agents.

D. Han, K. Son, Hwan-Mook Kim, 2006, Bioorganic & medicinal chemistry.

Obovatol inhibits colorectal cancer growth by inhibiting tumor cell proliferation and inducing apoptosis.

Yeong-Rim Kang, K. Bae, Hyelee Kim, 2008, Bioorganic & medicinal chemistry.

Inhibitory effect of 2'-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-kappa B activation in RAW 264.7 cells.

Sun Young Lee, J. Hong, H. Yoo, 2005, Biochemical pharmacology.

Synthesis and biological evaluation of cinnamyl compounds as potent antitumor agents.

Su-Hyung Hong, D. Han, K. Son, 2007, Bioorganic & medicinal chemistry letters.

2′-Benzoyloxycinnamaldehyde Induces Apoptosis in Human Carcinoma via Reactive Oxygen Species*

D. Han, K. Son, Hwan-Mook Kim, 2004, Journal of Biological Chemistry.

Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells.

D. Jeong, D. Han, B. Kwon, 2013, Bioorganic & medicinal chemistry letters.

Cosmomycin C inhibits signal transducer and activator of transcription 3 (STAT3) pathways in MDA-MB-468 breast cancer cell.

T. Oh, D. Han, K. Son, 2011, Bioorganic & medicinal chemistry.

Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway.

D. Han, K. Son, B. Kwon, 2006, Life sciences.

Association of Grb7 with Phosphoinositides and Its Role in the Regulation of Cell Migration*

J. Guan, D. Han, Tang-Long Shen, 2002, The Journal of Biological Chemistry.

Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.

Jennifer L. Harris, S. Kasibhatla, D. Han, 2016, ACS medicinal chemistry letters.

Biological evaluation of KRIBB3 analogs as a microtubule polymerization inhibitor.

D. Han, B. Kwon, Ki Deok Shin, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of KRIBB3 Analogues on a Proliferation of HCT-116 Colorectal Cancer Cells

D. Han, B. Kwon, Ki Deok Shin, 2010 .

KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells.

Yeong-Rim Kang, D. Han, K. Son, 2008, Biochemical pharmacology.

Role of Grb7 Targeting to Focal Contacts and Its Phosphorylation by Focal Adhesion Kinase in Regulation of Cell Migration*

J. Guan, D. Han, Tang-Long Shen, 2000, The Journal of Biological Chemistry.

Apoptosis induction of 2'-hydroxycinnamaldehyde as a proteasome inhibitor is associated with ER stress and mitochondrial perturbation in cancer cells.

Su-Hyung Hong, D. Han, K. Son, 2007, Biochemical pharmacology.

Design, synthesis, and structure-activity-relationship of phenyl imidazoles as potent Smoothened antagonists.

D. Han, T. Tuntland, N. Englund, 2012, Bioorganic & medicinal chemistry letters.

Synthesis, modeling, and crystallographic study of 3,4-disubstituted-1,2,5-oxadiazoles and evaluation of their ability to decrease STAT3 activity

A. Pedretti, F. Meneghetti, S. Villa, 2010 .

Analysis of FAK‐associated signaling pathways in the regulation of cell cycle progression

J. Guan, D. Han, Jihe Zhao, 2000, FEBS letters.

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist.

M. Warmuth, J. Williams, S. Peukert, 2010, ACS medicinal chemistry letters.

S-Benproperine, an Active Stereoisomer of Benproperine, Suppresses Cancer Migration and Tumor Metastasis by Targeting ARPC2

D. Han, B. Kwon, Sangku Lee, 2022, Pharmaceuticals.

Ureido-Pyridazinone Derivatives: Insights into the Structural and Conformational Properties for STAT3 Inhibition

A. Asai, F. Meneghetti, S. Villa, 2015 .

Cinnamaldehydes in Cancer Chemotherapy

Su-Hyung Hong, D. Han, B. Kwon, 2016, Phytotherapy research : PTR.

Blocking Tumor Cell Migration and Invasion with Biphenyl Isoxazole Derivative KRIBB3, a Synthetic Molecule That Inhibits Hsp27 Phosphorylation*

D. Han, K. Son, B. Kwon, 2005, Journal of Biological Chemistry.

Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino.

D. Han, K. Son, B. Kwon, 2005, Bioorganic & medicinal chemistry.

Anti-tumor activity of the farnesyl-protein transferase inhibitors arteminolides, isolated from Artemisa.

D. Han, K. Son, C. Lee, 2003, Bioorganic & medicinal chemistry.

Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells.

D. Han, B. Kwon, Seung-Nam Jung, 2015, Biochemical pharmacology.

Anti-tumor abietane diterpenes from the cones of Sequoia sempervirens.

D. Han, K. Son, B. Kwon, 2005, Bioorganic & medicinal chemistry letters.

The Natural Compound Cantharidin Induces Cancer Cell Death through Inhibition of Heat Shock Protein 70 (HSP70) and Bcl-2-associated Athanogene Domain 3 (BAG3) Expression by Blocking Heat Shock Factor 1 (HSF1) Binding to Promoters*

D. Han, B. Kwon, Byoung-Mog Kwon, 2013, The Journal of Biological Chemistry.

KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to the hsp70 Promoter*

D. Han, B. Kwon, Dae-Seop Shin, 2010, The Journal of Biological Chemistry.

KRIBB53 binds to OCT4 and enhances its degradation through the proteasome, causing apoptotic cell death of OCT4-positive testicular germ cell tumors

D. Han, B. Kwon, Joo Ae Kim, 2018, Carcinogenesis.

Identification of p130Cas as a Mediator of Focal Adhesion Kinase–promoted Cell Migration

S. Hanks, J. Guan, D. Han, 1998, The Journal of cell biology.

The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

J. Guan, D. Han, Tang-Long Shen, 2001, Oncogene.

Targeting HSF1 as a Therapeutic Strategy for Multiple Mechanisms of EGFR Inhibitor Resistance in EGFR Mutant Non-Small-Cell Lung Cancer

Bo-Kyung Kim, D. Han, B. Kwon, 2021, Cancers.

Ginkgetin inhibits the growth of DU−145 prostate cancer cells through inhibition of signal transducer and activator of transcription 3 activity

D. Han, C. Lee, B. Kwon, 2015, Cancer science.

Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3)

D. Jeong, S. Ryu, D. Han, 2006, Natural product research.

Confirmation of a linkage between H‐Ras and MMP‐13 expression as well as MMP‐9 by chemical genomic approach

Cheol‐Hee Kim, D. Han, K. Son, 2006, International journal of cancer.

EphB1 Associates with Grb7 and Regulates Cell Migration*

J. Guan, D. Han, H. Miao, 2002, The Journal of Biological Chemistry.

PPARγ agonists induce adipocyte differentiation by modulating the expression of Lipin-1, which acts as a PPARγ phosphatase.

So young Lee, D. Han, B. Kwon, 2016, The international journal of biochemistry & cell biology.

Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity.

D. Jeong, S. Ryu, D. Han, 2012, Bioorganic & medicinal chemistry letters.

Association of Focal Adhesion Kinase with Grb7 and Its Role in Cell Migration*

J. Guan, D. Han, D. C. Han, 1999, The Journal of Biological Chemistry.

Identification of a novel interaction between integrin β1 and 14-3-3β

J. Guan, D. Han, L. G. Rodríguez, 2001, Oncogene.

2′‐Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation

Cheol‐Hee Kim, D. Han, B. Kwon, 2018, Cancer science.

Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells.

Cheol‐Hee Kim, D. Han, B. Kwon, 2018, Bioorganic & medicinal chemistry letters.

Fisetin, a dietary flavonoid, induces apoptosis of cancer cells by inhibiting HSF1 activity through blocking its binding to the hsp70 promoter.

Moonil Kim, D. Han, B. Kwon, 2015, Carcinogenesis.

Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis

S. Chi, D. Han, C. Lee, 2019, Biochemical pharmacology.

2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2.

S. Chi, D. Han, B. Kwon, 2018, Cancer letters.

Geranylnaringenin (CG902) inhibits constitutive and inducible STAT3 activation through the activation of SHP‐2 tyrosine phosphatase

D. Han, B. Kwon, O. Nash, 2017, Biochemical pharmacology.

8‐Epi‐xanthatin induces the apoptosis of DU145 prostate carcinoma cells through signal transducer and activator of transcription 3 inhibition and reactive oxygen species generation

S. Chi, D. Han, B. Kwon, 2020, Phytotherapy research : PTR.

Inhibition of STAT3 activation by KT-18618 via the disruption of the interaction between JAK3 and STAT3.

D. Han, C. Lee, B. Kwon, 2014, Biochemical pharmacology.

Phosphatase of regenerating liver‐3 promotes migration and invasion by upregulating matrix metalloproteinases‐7 in human colorectal cancer cells

Su-Hyung Hong, D. Han, C. Lee, 2012, International journal of cancer.

Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)

D. Han, B. Kwon, S. Yun, 2021, Molecules.

Ginkgetin induces G2-phase arrest in HCT116 colon cancer cells through the modulation of b‑Myb and miRNA34a expression.

Yeong-Rim Kang, D. Han, B. Kwon, 2017, International journal of oncology.

Ginkgetin induces G 2-phase arrest in HCT 116 colon cancer cells through the modulation of b-Myb and miRNA 34 a expression

Yeong-Rim Kang, D. Han, B. Kwon, 2022 .

Methyllucidone inhibits STAT3 activity by regulating the expression of the protein tyrosine phosphatase MEG2 in DU145 prostate carcinoma cells.

D. Han, B. Kwon, J. Y. Park, 2018, Bioorganic & Medicinal Chemistry Letters.

2-Hydroxycurcuminoid induces apoptosis of human tumor cells through the reactive oxygen species-mitochondria pathway.

Su-Hyung Hong, D. Han, B. Kwon, 2011, Bioorganic & medicinal chemistry letters.

2′-Benzoyloxycinnamaldehyde Inhibits Tumor Growth in H-ras12V Transgenic Mice via Downregulation of Metallothionein

Dae-Yeul Yu, D. Han, B. Kwon, 2009, Nutrition and cancer.

Artocarpus altilis (Parkinson) Fosberg Extracts and Geranyl Dihydrochalcone Inhibit STAT3 Activity in Prostate Cancer DU145 Cells

D. Han, C. Lee, B. Kwon, 2015, Phytotherapy research : PTR.

Inhibitory effect of obovatal on the migration and invasion of HT1080 cells via the inhibition of MMP-2.

D. Han, K. Son, B. Kwon, 2007, Bioorganic & medicinal chemistry.

Investigation of cell cycle arrest effects of actinomycin D at G1 phase using proteomic methods in B104-1-1 cells.

D. Han, K. Son, B. Kwon, 2005, The international journal of biochemistry & cell biology.

Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells.

D. Jeong, D. Han, B. Kwon, 2013, Bioorganic & medicinal chemistry letters.