Charles R. Holst

发表

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

Manel Esteller, K. Chew, J. Herman, 2003, Cancer research.

Genetic and Epigenetic Changes in Mammary Epithelial Cells May Mimic Early Events in Carcinogenesis

Thea D. Tlsty, Jianmin Zhang, T. Tlsty, 2004, Journal of Mammary Gland Biology and Neoplasia.

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

Thea D. Tlsty, Martha R. Stampfer, L. Haupt, 2001, Nature.

High-Content, High-Throughput Analysis of Cell Cycle Perturbations Induced by the HSP90 Inhibitor XL888

M. Gerritsen, S. Crawley, Charles R. Holst, 2011, PLoS ONE.

p 16 INK 4 a Modulates p 53 in Primary Human Mammary Epithelial Cells

Jianmin Zhang, T. Tlsty, C. Pickering, 2006 .

p16INK4a modulates p53 in primary human mammary epithelial cells.

Jianmin Zhang, T. Tlsty, C. Pickering, 2006, Cancer research.

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

D. Davis, J. Trimmer, K. Hoff, 2018, PloS one.

Loss of Chromosomal Integrity in Human Mammary Epithelial Cells Subsequent to Escape from Senescence

L. Haupt, T. Tlsty, S. Romanov, 2001, Journal of mammary gland biology and neoplasia.

Discovery of XL413, a potent and selective CDC7 inhibitor.

Wei Xu, Charles R. Holst, J. Nuss, 2012, Bioorganic & medicinal chemistry letters.

human mammary cells spontaneously escape senescence and acquire genomic changes.

L. Haupt, T. Tlsty, M. Stampfer, 2022 .

p16 Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

T. Tlsty, Charles R. Holst, Veena Singla, 2006 .

Inactivation of p53 Function in Cultured Human Mammary Epithelial Cells Turns the Telomere-Length Dependent Senescence Barrier from Agonescence into Crisis

T. Tlsty, M. Stampfer, J. Garbe, 2007, Cell cycle.

Bi-allelic CCDC47 Variants Cause a Disorder Characterized by Woolly Hair, Liver Dysfunction, Dysmorphic Features, and Global Developmental Delay.

Ellen F. Macnamara, J. Lupski, E. Puffenberger, 2018, American journal of human genetics.

Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy

Euan A Ashley, Enrico Bertini, Matthew B Klein, 2019, PloS one.

Methylation of p 16 INK 4 a Promoters Occurs in Vivo in Histologically Normal Human Mammary Epithelia 1

K. Chew, J. Herman, S. Baylin, 2003 .

Secreted Sulfatases Sulf1 and Sulf2 Have Overlapping yet Essential Roles in Mouse Neonatal Survival

M. Tessier-Lavigne, G. Frantz, R. Carano, 2007, PloS one.

p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Jianmin Zhang, T. Tlsty, Charles R. Holst, 2006, PLoS biology.

Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors.

Charles R. Holst, J. Nuss, Xiang Wu, 2012, Journal of medicinal chemistry.

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

Lewis L Lanier, Paul H. Bessette, L. K. Ely, 2018, Nature Medicine.